Diethyl Sulfide

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    352-93-2

    Molecular formula
    C4H10S

    SMILES
    CCSCC

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Sulfurous 86.22%
    Meaty 73.49%
    Onion 67.73%
    Garlic 66.35%
    Vegetable 60.5%
    Alliaceous 60.43%
    Savory 55.35%
    Coffee 42.6%
    Cooked 42.09%
    Cabbage 38.78%

     

    Flavor
    Sulfurous 67.6%
    Onion 56.82%
    Garlic 43.77%
    Meaty 43.0%
    Sulfury 42.41%
    Cabbage 35.63%
    Green 34.76%
    Vegetable 34.53%
    Ethereal 32.11%
    Fishy 32.1%

     

    Odor impact est.
    High

    Odor threshold

    • Odor Threshold Low: 0.0008 [mmHg]. Odor Threshold High: 0.0054 [mmHg]. [HSDB] Odor threshold from CHEMINFO

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    8.4 (weak base)

    Molecular weight
    90.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -103.9 °C
    • -102.05 °C

    Boiling point

    • 92.1 °C
    • 90.00 to 93.00 °C. @ 760.00 mm Hg

    Flash point

    • -3.74 ˚C est.
    • -6.7 °C
    • -10 °C (14 °F) closed cup

    Solubility expt.

    • Soluble in ethanol, diethyl ether; slightly soluble in carbon tetrachloride.
    • Soluble in oxygenated solvents.
    • Miscible with alcohol, ether
    • In water, 3130 mg/L at 25 °C
    • 3.13 mg/mL at 20 °C
    • insoluble in water; miscible in alcohol and oil

  • Synonyms

    • Diethyl sulfide
    • Ethyl sulfide
    • 352-93-2
    • Ethyl thioether
    • ethylsulfanylethane
    • 3-Thiapentane
    • Thioethyl ether
    • Ethylthioethane
    • Diethylthioether
    • Diethyl sulphide
    • 1,1-Thiobisethane
    • 1,1'-THIOBISETHANE
    • Diethyl thioether
    • Ethyl monosulfide
    • Ethane, 1,1'-thiobis-
    • Diethylsulfid
    • Sulfodor
    • Sulfodor [Czech]
    • 1-(Ethylsulfanyl)ethane
    • 1,1'-thiodiethane
    • (ethylsulfanyl)ethane
    • Diethylsulfid [Czech]
    • ethylsulfanyl-ethane
    • NSC 75157
    • HSDB 5563
    • EINECS 206-526-9
    • UN2375
    • DTXSID5027146
    • CHEBI:27710
    • AI3-18785
    • 9191Y76OTC
    • (C2H5)2S
    • 1,1'-sulfanediyldiethane
    • MFCD00009270
    • NSC-75157
    • ETHYL SULFIDE [MI]
    • DIETHYL SULFIDE [FHFI]
    • DIETHYL SULFIDE [HSDB]
    • DTXCID507146
    • FEMA NO. 3825
    • THIOBISETHANE, 1,1'-
    • EC 206-526-9
    • Sulfodor (Czech)
    • Diethylsulfid (Czech)
    • diethylsulfide
    • Ethylsulfide
    • ethyl sulfides
    • Diethyl sulfane
    • UNII-9191Y76OTC
    • 3Thiapentane
    • (ethylthio)ethane
    • 1,1'Thiobisethane
    • Ethyl sulfide, 8CI
    • 1,1"-Thiobisethane
    • Ethane,1'-thiobis-
    • Ethane, 1,1'thiobis
    • 1,1'-Thiobis-Ethane
    • Diethyl sulfide, 98%
    • Diethyl sulfide [UN2375] [Flammable liquid]
    • 1-(Ethylsulfanyl)ethane #
    • 1,1'-Thiobisethane, 9CI
    • Diethyl sulfide, 98%, FG
    • CHEMBL117181
    • WLN: 2S2
    • CHEBI:23996
    • FEMA 3825
    • NSC75157
    • Diethyl sulfide, analytical standard
    • Tox21_200927
    • AKOS015843725
    • UN 2375
    • USEPA/OPP Pesticide Code: 125101
    • NCGC00248878-01
    • NCGC00258481-01
    • CAS-352-93-2
    • DB-048771
    • Diethyl sulfide, puriss., >=99.0% (GC)
    • E0176
    • NS00005184
    • EN300-97334
    • C02272
    • W13859
    • Diethyl sulfide [UN2375] [Flammable liquid]
    • A822711
    • Q420998
    • 206-526-9

  • Applications

    Diethyl sulfide, also known as thioethoxyethane, CAS number 352-93-2, is a volatile organosulfur compound with a pungent garlic-onion odour whose versatility spans laboratory synthesis and large-scale manufacturing: it functions as a hydrophobic, moisture-resistant solvent in alkylations, free-radical polymerisations and metal extraction; serves as a pivotal intermediate for generating sulfonium salts used in Corey-Chaykovsky epoxidations to access highly pure epoxides and aziridines; is blended into hydrocarbon fuels as a tracer and calibration standard for sulfur-specific detectors; finds roles in pesticide formulations, crude-oil desulfurisation and speciality adhesive systems; and, owing to its distinctive smell, is employed in sensory science for olfaction studies, leak-detector testing, imparting subtle onion notes to flavour blends at trace levels, and masking or balancing fragrances in certain industrial perfume bases.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 367.73
    methanol 214.7
    isopropanol 285.38
    water 0.09
    ethyl acetate 809.51
    n-propanol 399.99
    acetone 669.03
    n-butanol 500.86
    acetonitrile 476.2
    DMF 326.5
    toluene 570.63
    isobutanol 276.69
    1,4-dioxane 1246.76
    methyl acetate 540.65
    THF 2281.49
    2-butanone 741.87
    n-pentanol 289.57
    sec-butanol 385.23
    n-hexane 421.97
    ethylene glycol 34.17
    NMP 786.43
    cyclohexane 985.72
    DMSO 532.12
    n-butyl acetate 1810.75
    n-octanol 302.66
    chloroform 2112.55
    n-propyl acetate 537.16
    acetic acid 377.95
    dichloromethane 1592.64
    cyclohexanone 1627.11
    propylene glycol 67.3
    isopropyl acetate 467.18
    DMAc 281.14
    2-ethoxyethanol 264.87
    isopentanol 362.16
    n-heptane 1007.48
    ethyl formate 440.51
    1,2-dichloroethane 925.87
    n-hexanol 738.67
    2-methoxyethanol 415.99
    isobutyl acetate 287.43
    tetrachloromethane 696.25
    n-pentyl acetate 647.34
    transcutol 1175.72
    n-heptanol 322.42
    ethylbenzene 235.63
    MIBK 354.97
    2-propoxyethanol 695.99
    tert-butanol 375.63
    MTBE 560.67
    2-butoxyethanol 383.65
    propionic acid 369.66
    o-xylene 307.43
    formic acid 52.24
    diethyl ether 1064.26
    m-xylene 288.21
    p-xylene 285.86
    chlorobenzene 766.5
    dimethyl carbonate 116.11
    n-octane 242.05
    formamide 83.47
    cyclopentanone 1552.28
    2-pentanone 732.29
    anisole 354.03
    cyclopentyl methyl ether 1179.34
    gamma-butyrolactone 1372.85
    1-methoxy-2-propanol 340.44
    pyridine 1147.78
    3-pentanone 581.2
    furfural 962.19
    n-dodecane 103.2
    diethylene glycol 256.43
    diisopropyl ether 344.76
    tert-amyl alcohol 411.97
    acetylacetone 528.45
    n-hexadecane 121.59
    acetophenone 306.13
    methyl propionate 428.98
    isopentyl acetate 1041.3
    trichloroethylene 1602.92
    n-nonanol 276.08
    cyclohexanol 710.55
    benzyl alcohol 218.49
    2-ethylhexanol 690.22
    isooctanol 260.03
    dipropyl ether 1548.73
    1,2-dichlorobenzene 623.9
    ethyl lactate 135.68
    propylene carbonate 763.64
    n-methylformamide 218.44
    2-pentanol 388.87
    n-pentane 407.93
    1-propoxy-2-propanol 800.14
    1-methoxy-2-propyl acetate 712.7
    2-(2-methoxypropoxy) propanol 265.0
    mesitylene 207.91
    ε-caprolactone 1275.09
    p-cymene 376.29
    epichlorohydrin 1119.94
    1,1,1-trichloroethane 1303.69
    2-aminoethanol 94.1
    morpholine-4-carbaldehyde 712.23
    sulfolane 1224.98
    2,2,4-trimethylpentane 125.45
    2-methyltetrahydrofuran 1860.28
    n-hexyl acetate 642.94
    isooctane 99.55
    2-(2-butoxyethoxy)ethanol 416.98
    sec-butyl acetate 331.11
    tert-butyl acetate 494.95
    decalin 230.52
    glycerin 83.34
    diglyme 863.49
    acrylic acid 263.61
    isopropyl myristate 290.24
    n-butyric acid 691.17
    acetyl acetate 460.04
    di(2-ethylhexyl) phthalate 171.96
    ethyl propionate 420.61
    nitromethane 545.9
    1,2-diethoxyethane 1145.84
    benzonitrile 492.96
    trioctyl phosphate 159.37
    1-bromopropane 1040.95
    gamma-valerolactone 1325.47
    n-decanol 199.19
    triethyl phosphate 315.24
    4-methyl-2-pentanol 184.05
    propionitrile 546.96
    vinylene carbonate 621.02
    1,1,2-trichlorotrifluoroethane 584.26
    DMS 293.68
    cumene 152.8
    2-octanol 249.72
    2-hexanone 539.01
    octyl acetate 331.62
    limonene 820.57
    1,2-dimethoxyethane 638.65
    ethyl orthosilicate 326.48
    tributyl phosphate 230.34
    diacetone alcohol 351.84
    N,N-dimethylaniline 200.09
    acrylonitrile 472.5
    aniline 442.09
    1,3-propanediol 182.79
    bromobenzene 877.14
    dibromomethane 1378.82
    1,1,2,2-tetrachloroethane 1321.93
    2-methyl-cyclohexyl acetate 556.83
    tetrabutyl urea 264.1
    diisobutyl methanol 414.33
    2-phenylethanol 379.82
    styrene 322.52
    dioctyl adipate 322.59
    dimethyl sulfate 162.79
    ethyl butyrate 1060.07
    methyl lactate 126.39
    butyl lactate 328.51
    diethyl carbonate 519.24
    propanediol butyl ether 232.81
    triethyl orthoformate 702.95
    p-tert-butyltoluene 362.54
    methyl 4-tert-butylbenzoate 286.49
    morpholine 1232.27
    tert-butylamine 328.2
    n-dodecanol 160.21
    dimethoxymethane 344.24
    ethylene carbonate 586.11
    cyrene 244.14
    2-ethoxyethyl acetate 592.33
    2-ethylhexyl acetate 1006.29
    1,2,4-trichlorobenzene 651.91
    4-methylpyridine 902.9
    dibutyl ether 887.41
    2,6-dimethyl-4-heptanol 414.33
    DEF 599.09
    dimethyl isosorbide 651.78
    tetrachloroethylene 1002.36
    eugenol 241.92
    triacetin 367.32
    span 80 359.48
    1,4-butanediol 68.51
    1,1-dichloroethane 1029.62
    2-methyl-1-pentanol 252.05
    methyl formate 185.91
    2-methyl-1-butanol 361.27
    n-decane 211.88
    butyronitrile 774.0
    3,7-dimethyl-1-octanol 349.57
    1-chlorooctane 445.96
    1-chlorotetradecane 166.91
    n-nonane 252.5
    undecane 138.05
    tert-butylcyclohexane 179.04
    cyclooctane 359.65
    cyclopentanol 670.15
    tetrahydropyran 2010.96
    tert-amyl methyl ether 498.49
    2,5,8-trioxanonane 513.89
    1-hexene 676.98
    2-isopropoxyethanol 208.97
    2,2,2-trifluoroethanol 113.53
    methyl butyrate 563.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Pineapple pulp Ananas comosus (L.) Merr., fam. Bromeliaceae 0.1%