Dichlorotetrafluoroethane

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  • Identifiers

    CAS number
    76-14-2

    Molecular formula
    C2Cl2F4

    SMILES
    C(C(F)(F)Cl)(F)(F)Cl

    Safety labels

    Compressed Gas
    Compressed Gas

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 54.9%
    Sweet 24.94%
    Fishy 24.13%
    Woody 23.23%
    Balsamic 19.7%
    Cooling 18.42%
    Dry 17.13%
    Clean 17.02%
    Animal 16.52%
    Amber 14.33%

     

    Flavor
    Odorless 33.14%
    Sulfurous 21.31%
    Bland 20.35%
    Mild 18.63%
    Sulfury 18.09%
    Glue 17.85%
    Bloody 17.84%
    Sweet-like 17.71%
    Bouillon 17.57%
    Skunky 17.42%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.8

    pKa est.
    2.56 (strong acid)

    Molecular weight
    170.92 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -137 °F (USCG, 1999)
    • -92.53 °C
    • -94 °C
    • -137 °F

    Boiling point

    • 38.8 °F at 760 mmHg (USCG, 1999)
    • 3.5 °C
    • 4.1 °C
    • 38 °F

    Flash point

    • 1.72 ˚C est.

    Solubility expt.

    • 0.01 % (NIOSH, 2024)
    • Souble in alcohol, ether
    • 0.013% in water
    • In water, 130 mg/L at 25 °C
    • Solubility in water at 25 °C: none
    • 0.01%

  • Synonyms

    • Dichlorotetrafluoroethane
    • 1,2-Dichlorotetrafluoroethane
    • 76-14-2
    • Cryofluorane
    • 1,2-Dichloro-1,1,2,2-tetrafluoroethane
    • CFC-114
    • Refrigerant 114
    • Frigiderm
    • FREON 114
    • Halocarbon 114
    • Propellant 114
    • Fluorocarbon 114
    • Fluorane 114
    • Genetron 114
    • Genetron 316
    • Arcton 33
    • Criofluorano
    • Cryfluorane
    • Cryofluorane [INN]
    • Arcton 114
    • Frigen 114
    • Ethane, 1,2-dichloro-1,1,2,2-tetrafluoro-
    • Caswell No. 326A
    • Ledon 114
    • F 114 (halocarbon)
    • R 114 (halocarbon)
    • Ucon 114
    • Cryofluoranum [INN-Latin]
    • sym-Dichlorotetrafluoroethane
    • tetrafluordichlorethan
    • Criofluorano [INN-Spanish]
    • Cryofluorane (INN)
    • CCRIS 8973
    • HSDB 146
    • Chlorofluorocarbon 114
    • CFC 114
    • FKW 114
    • Ethane, 1,2-dichlorotetrafluoro-
    • UNII-6B5VVT93AR
    • F 114
    • EINECS 200-937-7
    • FC 114
    • Refrigerant R114
    • Dichlorotetrafluoroethane [NF]
    • NSC-760428
    • BRN 1740333
    • Isotron 114
    • 1,1,2,2-Tetrafluoro-1,2-dichloroethane
    • R 114
    • CRYOFLUORANE [MI]
    • s-Dichlorotetrafluoroethane
    • 6B5VVT93AR
    • (CF2Cl)2
    • CRYOFLUORANE [MART.]
    • Dichlorotetrafluoroethane (NF)
    • 1,2-Dichloro-1,1,2,2-tetrafluoro-ethane
    • DTXSID8026434
    • P-114
    • 4-01-00-00137 (Beilstein Handbook Reference)
    • Dichloro-1,1,2,2-tetrafluoroethane
    • DICHLOROTETRAFLUOROETHANE [II]
    • 1,2-DICHLOROTETRAFLUORO-ETHANE
    • NSC 760428
    • TETRAFLUORDICHLORETHAN [WHO-DD]
    • DICHLOROTETRAFLUOROETHANE [HSDB]
    • DICHLOROTETRAFLUOROETHANE [VANDF]
    • Cryofluoranum (INN-Latin)
    • Criofluorano (INN-Spanish)
    • CRYOFLUORANE (MART.)
    • Cryofluoranum [Latin]
    • Cryofluoranum
    • Cryoflurane
    • DICHLOROTETRAFLUOROETHANE (II)
    • UN1958
    • EPA Pesticide Chemical Code 326200
    • Cryofluoran
    • FREON-114
    • 1,2-Dichlorotetrafluoroethane Solution, 2000 microg/mL in Methanol
    • Dwuchloroczterofluoroetan [Polish]
    • Genetron114
    • Fluorocarbon-114
    • EINECS 215-300-9
    • Caswell No 326A
    • Freon114
    • Halon242
    • CClF2CClF2
    • dichlortetrafluoroethane
    • Dwuchloroczterofluoroetan
    • Halon 242
    • Flon-114
    • SCHEMBL865
    • symDichlorotetrafluoroethane
    • 1,2dichlorotetrafluoroethane
    • UNII-WG83EP1472
    • Ethane, 1,2dichlorotetrafluoro
    • CFC114
    • CHEMBL325436
    • DTXCID906434
    • FRON 114
    • REFRIGERANT GAS R-114
    • DTXSID5041857
    • HMS3264G16
    • Pharmakon1600-01502370
    • 1,2-DICHLOROPERFLUOROETHANE
    • MFCD00000778
    • NSC760428
    • 1,1,2,2Tetrafluoro1,2dichloroethane
    • 1,2Dichloro1,1,2,2tetrafluoroethane
    • AKOS015915972
    • CCG-213721
    • FD84702
    • Dichlorotetrafluoroethane (ACGIH:OSHA)
    • Ethane, 1,2dichloro1,1,2,2tetrafluoro
    • 1,2-Dichlorotetrafluoroethane, >=99.5%
    • DB-056030
    • 76-14-2; 1320-37-2(mixedisomers)
    • D0417
    • NS00041206
    • D03790
    • AB01563180_01
    • Q420380
    • SR-01000944235
    • SR-01000944235-1
    • 1,2-Dichlorotetrafluoroethane 100 microg/mL in Methanol

  • Applications

    Dichlorotetrafluoroethane (CAS 76-14-2) is used primarily as a refrigerant in older HVAC/R systems; it has historically served as a blowing agent for polyurethane foams used in insulation and appliance components; it may be used as a solvent or cleaning medium in certain industrial formulations or degreasing processes for precision parts; it acts as a chemical intermediate or building block in the synthesis of fluorinated polymers and other specialty chemicals; its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 50.24
    methanol 84.69
    isopropanol 32.08
    water 17.98
    ethyl acetate 24.34
    n-propanol 32.25
    acetone 70.18
    n-butanol 23.1
    acetonitrile 40.07
    DMF 234.79
    toluene 9.29
    isobutanol 20.42
    1,4-dioxane 43.11
    methyl acetate 33.16
    THF 82.96
    2-butanone 39.44
    n-pentanol 18.8
    sec-butanol 25.79
    n-hexane 5.96
    ethylene glycol 38.61
    NMP 211.41
    cyclohexane 13.83
    DMSO 503.41
    n-butyl acetate 20.17
    n-octanol 17.6
    chloroform 25.64
    n-propyl acetate 18.35
    acetic acid 45.2
    dichloromethane 40.54
    cyclohexanone 42.9
    propylene glycol 22.64
    isopropyl acetate 17.23
    DMAc 192.93
    2-ethoxyethanol 58.9
    isopentanol 18.2
    n-heptane 13.04
    ethyl formate 26.24
    1,2-dichloroethane 36.72
    n-hexanol 18.75
    2-methoxyethanol 85.41
    isobutyl acetate 7.8
    tetrachloromethane 7.16
    n-pentyl acetate 18.15
    transcutol 94.11
    n-heptanol 15.39
    ethylbenzene 7.18
    MIBK 18.92
    2-propoxyethanol 46.73
    tert-butanol 32.29
    MTBE 24.77
    2-butoxyethanol 31.96
    propionic acid 26.48
    o-xylene 12.61
    formic acid 59.28
    diethyl ether 34.28
    m-xylene 8.56
    p-xylene 7.95
    chlorobenzene 6.52
    dimethyl carbonate 24.59
    n-octane 5.83
    formamide 115.59
    cyclopentanone 58.97
    2-pentanone 31.15
    anisole 17.09
    cyclopentyl methyl ether 35.92
    gamma-butyrolactone 62.75
    1-methoxy-2-propanol 61.02
    pyridine 40.74
    3-pentanone 31.18
    furfural 57.77
    n-dodecane 3.49
    diethylene glycol 50.17
    diisopropyl ether 12.02
    tert-amyl alcohol 27.54
    acetylacetone 37.13
    n-hexadecane 3.75
    acetophenone 24.21
    methyl propionate 32.88
    isopentyl acetate 14.41
    trichloroethylene 34.78
    n-nonanol 16.73
    cyclohexanol 26.7
    benzyl alcohol 20.39
    2-ethylhexanol 13.94
    isooctanol 12.35
    dipropyl ether 28.72
    1,2-dichlorobenzene 7.54
    ethyl lactate 19.76
    propylene carbonate 24.83
    n-methylformamide 98.47
    2-pentanol 19.98
    n-pentane 10.79
    1-propoxy-2-propanol 37.74
    1-methoxy-2-propyl acetate 27.91
    2-(2-methoxypropoxy) propanol 38.67
    mesitylene 7.81
    ε-caprolactone 35.81
    p-cymene 11.42
    epichlorohydrin 50.17
    1,1,1-trichloroethane 12.28
    2-aminoethanol 41.84
    morpholine-4-carbaldehyde 127.36
    sulfolane 130.0
    2,2,4-trimethylpentane 3.93
    2-methyltetrahydrofuran 43.68
    n-hexyl acetate 19.79
    isooctane 2.7
    2-(2-butoxyethoxy)ethanol 43.81
    sec-butyl acetate 11.02
    tert-butyl acetate 18.14
    decalin 3.77
    glycerin 37.07
    diglyme 82.28
    acrylic acid 30.07
    isopropyl myristate 10.81
    n-butyric acid 22.24
    acetyl acetate 15.2
    di(2-ethylhexyl) phthalate 10.95
    ethyl propionate 18.77
    nitromethane 104.51
    1,2-diethoxyethane 32.35
    benzonitrile 16.15
    trioctyl phosphate 10.29
    1-bromopropane 22.77
    gamma-valerolactone 68.05
    n-decanol 13.46
    triethyl phosphate 14.53
    4-methyl-2-pentanol 12.2
    propionitrile 27.52
    vinylene carbonate 20.94
    1,1,2-trichlorotrifluoroethane 51.05
    DMS 20.53
    cumene 6.39
    2-octanol 11.98
    2-hexanone 20.09
    octyl acetate 13.75
    limonene 17.14
    1,2-dimethoxyethane 78.98
    ethyl orthosilicate 13.66
    tributyl phosphate 11.14
    diacetone alcohol 31.99
    N,N-dimethylaniline 24.94
    acrylonitrile 38.09
    aniline 18.84
    1,3-propanediol 35.02
    bromobenzene 5.38
    dibromomethane 31.74
    1,1,2,2-tetrachloroethane 35.34
    2-methyl-cyclohexyl acetate 15.99
    tetrabutyl urea 25.61
    diisobutyl methanol 12.56
    2-phenylethanol 17.67
    styrene 8.16
    dioctyl adipate 16.8
    dimethyl sulfate 53.43
    ethyl butyrate 20.18
    methyl lactate 32.45
    butyl lactate 19.79
    diethyl carbonate 13.85
    propanediol butyl ether 29.29
    triethyl orthoformate 18.29
    p-tert-butyltoluene 10.98
    methyl 4-tert-butylbenzoate 30.66
    morpholine 66.05
    tert-butylamine 24.28
    n-dodecanol 11.06
    dimethoxymethane 91.17
    ethylene carbonate 17.74
    cyrene 38.56
    2-ethoxyethyl acetate 22.98
    2-ethylhexyl acetate 12.25
    1,2,4-trichlorobenzene 10.25
    4-methylpyridine 32.29
    dibutyl ether 17.2
    2,6-dimethyl-4-heptanol 12.56
    DEF 67.67
    dimethyl isosorbide 54.44
    tetrachloroethylene 26.94
    eugenol 28.79
    triacetin 25.8
    span 80 27.4
    1,4-butanediol 22.13
    1,1-dichloroethane 18.33
    2-methyl-1-pentanol 13.87
    methyl formate 65.94
    2-methyl-1-butanol 18.53
    n-decane 5.78
    butyronitrile 21.83
    3,7-dimethyl-1-octanol 14.83
    1-chlorooctane 10.42
    1-chlorotetradecane 5.48
    n-nonane 5.97
    undecane 4.33
    tert-butylcyclohexane 2.99
    cyclooctane 6.51
    cyclopentanol 33.4
    tetrahydropyran 34.86
    tert-amyl methyl ether 25.58
    2,5,8-trioxanonane 65.34
    1-hexene 10.36
    2-isopropoxyethanol 34.28
    2,2,2-trifluoroethanol 29.69
    methyl butyrate 24.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction