D-Gluconic acid, delta-lactone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    54910-68-8

    Molecular formula
    C6H10O6

    SMILES
    C(C1C(C(C(C(=O)O1)O)O)O)O

  • Odor profile

    Fragrance
    Odorless 73.32%
    Caramellic 38.21%
    Sweet 35.67%
    Burnt 22.27%
    Clean 17.19%
    Milky 16.9%
    Woody 16.71%
    Sharp 16.27%
    Buttery 15.74%
    Malty 14.25%

     

    Flavor
    Sweet 70.29%
    Bitter 54.63%
    Odorless 48.82%
    Sweet-like 29.41%
    Very mild 24.98%
    Very slight 22.3%
    Cauliflower 22.07%
    Fenugreek 21.87%
    Caramel 21.63%
    Extremely sweet 20.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.0

    pKa est.
    4.39 (weak acid)

    Molecular weight
    178.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    977°C

    Flash point

    • 194.99 ˚C est.

  • Synonyms

    • D-Gluconic acid, delta-lactone
    • 3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one
    • 54910-68-8
    • Aldono-1,5-lactone
    • 52393-78-9
    • D-Gluconic acid, .delta.-lactone
    • Gluconic acid, .delta.-lactone, D-
    • D-glucono-delta-lactone
    • NSC 34393
    • delta-D-Mannonolactone
    • .delta.-Gluconolactone
    • 7506-65-2
    • D-Gluconic acid-1,5-lactone
    • D-(+)-Gluconic acid d-lactone
    • NSC34393
    • 1-Desoxyhexoson
    • 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one (non-preferred name)
    • NCGC00095002-01
    • an aldono-1,5-lactone
    • glucono-.delta.-lactone
    • Galactonic acid, 8CI,
    • Gluconic .delta.-lactone
    • D-.delta.-Gluconolactone
    • D-Glucono-.delta.-lactone
    • Gluconic acid-1,5-lactone
    • D-Gluconic .delta.-lactone
    • Oprea1_179629
    • SCHEMBL333412
    • SCHEMBL24637666
    • CHEBI:74105
    • BBL029193
    • NSC407014
    • STL146330
    • AKOS004119900
    • D-(+)-Gluconic acid-.delta. lactone
    • NSC-407014
    • SB45667
    • NCGC00095002-02
    • NCGC00095002-03
    • VS-09144
    • NS00006459
    • EN300-189501
    • 3,4,5-trihydroxy-6-hydroxymethyltetrahydropyran-2-one
    • Q27144414
    • 9A619B74-0102-4BA8-8133-87EB9FA4AEC6

  • Applications

    D-Gluconic acid, delta-lactone, CAS 54910-68-8, is primarily used as a slow-release acidulant in food processing to control acidity and is commonly used as a coagulation aid in tofu production; in cosmetics and personal care, it serves as a pH adjuster and mild acidulant in formulations; in cleaning and detergents, it acts as a chelating agent via hydrolysis to gluconic acid, supporting metal ion chelation and enhanced cleaning performance; in pharmaceuticals, it is used as an excipient and pH adjuster in a range of formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.66
    methanol 22.49
    isopropanol 1.31
    water 485.64
    ethyl acetate 0.56
    n-propanol 0.93
    acetone 0.96
    n-butanol 0.77
    acetonitrile 0.7
    DMF 111.63
    toluene 0.27
    isobutanol 0.58
    1,4-dioxane 4.28
    methyl acetate 0.4
    THF 1.81
    2-butanone 0.55
    n-pentanol 0.81
    sec-butanol 0.93
    n-hexane 0.11
    ethylene glycol 93.45
    NMP 85.66
    cyclohexane 0.51
    DMSO 886.26
    n-butyl acetate 0.49
    n-octanol 1.1
    chloroform 0.27
    n-propyl acetate 0.3
    acetic acid 2.67
    dichloromethane 0.67
    cyclohexanone 2.05
    propylene glycol 18.89
    isopropyl acetate 0.47
    DMAc 59.94
    2-ethoxyethanol 13.51
    isopentanol 0.7
    n-heptane 0.65
    ethyl formate 0.6
    1,2-dichloroethane 0.9
    n-hexanol 1.17
    2-methoxyethanol 33.04
    isobutyl acetate 0.14
    tetrachloromethane 0.21
    n-pentyl acetate 0.53
    transcutol 13.74
    n-heptanol 1.47
    ethylbenzene 0.23
    MIBK 0.55
    2-propoxyethanol 7.92
    tert-butanol 1.67
    MTBE 0.49
    2-butoxyethanol 5.47
    propionic acid 1.54
    o-xylene 0.72
    formic acid 121.66
    diethyl ether 0.56
    m-xylene 0.5
    p-xylene 0.27
    chlorobenzene 0.14
    dimethyl carbonate 2.54
    n-octane 0.27
    formamide 101.73
    cyclopentanone 1.82
    2-pentanone 0.6
    anisole 0.57
    cyclopentyl methyl ether 1.29
    gamma-butyrolactone 3.26
    1-methoxy-2-propanol 15.13
    pyridine 1.08
    3-pentanone 0.74
    furfural 7.19
    n-dodecane 0.16
    diethylene glycol 33.77
    diisopropyl ether 0.32
    tert-amyl alcohol 1.34
    acetylacetone 1.91
    n-hexadecane 0.17
    acetophenone 1.13
    methyl propionate 1.3
    isopentyl acetate 0.38
    trichloroethylene 0.73
    n-nonanol 1.07
    cyclohexanol 1.86
    benzyl alcohol 1.62
    2-ethylhexanol 0.82
    isooctanol 1.02
    dipropyl ether 1.12
    1,2-dichlorobenzene 0.3
    ethyl lactate 2.35
    propylene carbonate 1.29
    n-methylformamide 23.53
    2-pentanol 0.68
    n-pentane 0.18
    1-propoxy-2-propanol 4.77
    1-methoxy-2-propyl acetate 2.12
    2-(2-methoxypropoxy) propanol 6.33
    mesitylene 0.58
    ε-caprolactone 2.1
    p-cymene 0.59
    epichlorohydrin 2.01
    1,1,1-trichloroethane 0.15
    2-aminoethanol 29.38
    morpholine-4-carbaldehyde 55.28
    sulfolane 39.97
    2,2,4-trimethylpentane 0.11
    2-methyltetrahydrofuran 0.95
    n-hexyl acetate 0.63
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 8.46
    sec-butyl acetate 0.2
    tert-butyl acetate 0.67
    decalin 0.17
    glycerin 94.37
    diglyme 14.4
    acrylic acid 3.72
    isopropyl myristate 0.38
    n-butyric acid 1.03
    acetyl acetate 0.58
    di(2-ethylhexyl) phthalate 0.89
    ethyl propionate 0.45
    nitromethane 6.34
    1,2-diethoxyethane 1.36
    benzonitrile 0.56
    trioctyl phosphate 0.86
    1-bromopropane 0.24
    gamma-valerolactone 9.11
    n-decanol 0.89
    triethyl phosphate 1.01
    4-methyl-2-pentanol 0.53
    propionitrile 0.37
    vinylene carbonate 1.48
    1,1,2-trichlorotrifluoroethane 16.16
    DMS 1.05
    cumene 0.26
    2-octanol 0.8
    2-hexanone 0.39
    octyl acetate 0.56
    limonene 0.91
    1,2-dimethoxyethane 7.01
    ethyl orthosilicate 0.92
    tributyl phosphate 0.6
    diacetone alcohol 3.53
    N,N-dimethylaniline 1.42
    acrylonitrile 0.99
    aniline 0.8
    1,3-propanediol 13.6
    bromobenzene 0.12
    dibromomethane 0.37
    1,1,2,2-tetrachloroethane 1.16
    2-methyl-cyclohexyl acetate 0.59
    tetrabutyl urea 1.79
    diisobutyl methanol 0.88
    2-phenylethanol 1.52
    styrene 0.18
    dioctyl adipate 0.78
    dimethyl sulfate 13.41
    ethyl butyrate 0.66
    methyl lactate 9.48
    butyl lactate 1.51
    diethyl carbonate 0.47
    propanediol butyl ether 7.3
    triethyl orthoformate 0.95
    p-tert-butyltoluene 0.61
    methyl 4-tert-butylbenzoate 3.01
    morpholine 6.05
    tert-butylamine 0.75
    n-dodecanol 0.74
    dimethoxymethane 11.59
    ethylene carbonate 1.03
    cyrene 14.24
    2-ethoxyethyl acetate 1.0
    2-ethylhexyl acetate 0.35
    1,2,4-trichlorobenzene 0.43
    4-methylpyridine 0.77
    dibutyl ether 0.51
    2,6-dimethyl-4-heptanol 0.88
    DEF 6.23
    dimethyl isosorbide 9.03
    tetrachloroethylene 1.15
    eugenol 4.07
    triacetin 1.66
    span 80 5.06
    1,4-butanediol 9.91
    1,1-dichloroethane 0.18
    2-methyl-1-pentanol 0.62
    methyl formate 7.79
    2-methyl-1-butanol 0.68
    n-decane 0.24
    butyronitrile 0.33
    3,7-dimethyl-1-octanol 0.75
    1-chlorooctane 0.36
    1-chlorotetradecane 0.22
    n-nonane 0.26
    undecane 0.19
    tert-butylcyclohexane 0.09
    cyclooctane 0.4
    cyclopentanol 1.65
    tetrahydropyran 0.92
    tert-amyl methyl ether 0.76
    2,5,8-trioxanonane 14.98
    1-hexene 0.13
    2-isopropoxyethanol 4.97
    2,2,2-trifluoroethanol 8.91
    methyl butyrate 0.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction