Copper Gluconate

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  • Identifiers

    CAS number
    527-09-3

    Molecular formula
    C12H22CuO14

    SMILES
    C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cu+2]

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 84.06%
    Sweet 25.23%
    Caramellic 24.64%
    Buttery 18.19%
    Bitter 16.1%
    Sharp 15.07%
    Milky 14.98%
    Savory 14.02%
    Clean 14.01%
    Burnt 12.84%

     

    Flavor
    0%
    0%
    0%
    0%
    0%
    0%
    0%
    0%
    0%
    0%

     

    Odor impact est.
    Odorless

  • Properties

    pKa est.
    -348458.44 (strong acid)

    Molecular weight
    453.84 g/mol

    Melting point expt.

    • 155-157 °C /D-form/

    Flash point

    • 252.57 ˚C est.

    Solubility expt.

    • Light blue to bluish-green, odorless crystals and crystalline powder. Astringent taste. 30 g soluble in 100 ml water at 25 °C; slightly sol in alcohol; practically insol in most org solvents. /Hydrate/
    • Sol in water; insol in acetone, alcohol, ether

  • Synonyms

    • Copper gluconate
    • Copper(II) gluconate
    • 527-09-3
    • Copper(II)gluconate
    • CUPRIC GLUCONATE
    • Copper D-gluconate (1:2)
    • Copper(2+) D-gluconate, (1:2)
    • UNII-RV823G6G67
    • CCRIS 3652
    • HSDB 261
    • Bis(D-gluconato-O1,O2)copper
    • Gluconic acid, copper(2+) salt
    • Bis(D-gluconato)copper
    • CUPRUM GLUCONICUM
    • RV823G6G67
    • Copper gluconate (USP)
    • Copper gluconate [USP]
    • Copper, bis(D-gluconato-O1,O2)-
    • EINECS 208-408-2
    • COPPER (AS GLUCONATE)
    • copper;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
    • DTXSID4035960
    • Copper(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
    • Gluconic acid, copper(2+) salt (2:1), D-
    • Copper, bis (D-gluconato-O(sup 1),O(sup 2))-
    • Copper(II) D-gluconate
    • 13005-35-1
    • Copper di-D-gluconate
    • COPPER GLUCONATE (MART.)
    • COPPER GLUCONATE [MART.]
    • Gluconates
    • Gluconic Acid Copper(II) Salt
    • Gluconate, Copper
    • COPPER GLUCONATE (USP MONOGRAPH)
    • COPPER GLUCONATE [USP MONOGRAPH]
    • Cupric gluconate monohydrate
    • Copper, bis(D-gluconato)-
    • Pleo Cup
    • D-Gluconic acid copper (II) salt
    • Chelates of copper gluconate
    • SCHEMBL23076
    • CUPRIC GLUCONATE [MI]
    • COPPER GLUCONATE [FCC]
    • COPPER GLUCONATE [HSDB]
    • COPPER GLUCONATE [VANDF]
    • CUPRIC GLUCONATE [VANDF]
    • DTXCID2015960
    • CHEBI:31431
    • COPPER GLUCONATE [WHO-DD]
    • Copper,bis(D-gluconato-kO1,kO2)-
    • AKOS015901520
    • CS-W011576
    • DB11246
    • HY-W010860
    • MG07603
    • AS-14692
    • Copper, bis(D-gluconato-kappaO1,kappaO2)-
    • G0275
    • NS00079813
    • Gluconic acid, copper(2+) salt (2:1) D-
    • D02395
    • Q3109285
    • 208-408-2

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.09
    methanol 6.5
    isopropanol 0.32
    water 197.87
    ethyl acetate 0.12
    n-propanol 0.41
    acetone 0.34
    n-butanol 0.24
    acetonitrile 0.08
    DMF 18.63
    toluene 0.05
    isobutanol 0.14
    1,4-dioxane 0.47
    methyl acetate 0.09
    THF 0.5
    2-butanone 0.15
    n-pentanol 0.13
    sec-butanol 0.2
    n-hexane 0.04
    ethylene glycol 23.47
    NMP 22.44
    cyclohexane 0.12
    DMSO 179.5
    n-butyl acetate 0.08
    n-octanol 0.17
    chloroform 0.06
    n-propyl acetate 0.05
    acetic acid 2.94
    dichloromethane 0.1
    cyclohexanone 0.33
    propylene glycol 5.95
    isopropyl acetate 0.09
    DMAc 10.57
    2-ethoxyethanol 2.34
    isopentanol 0.13
    n-heptane 0.14
    ethyl formate 0.2
    1,2-dichloroethane 0.16
    n-hexanol 0.21
    2-methoxyethanol 10.63
    isobutyl acetate 0.01
    tetrachloromethane 0.08
    n-pentyl acetate 0.1
    transcutol 3.7
    n-heptanol 0.27
    ethylbenzene 0.04
    MIBK 0.09
    2-propoxyethanol 1.95
    tert-butanol 0.34
    MTBE 0.06
    2-butoxyethanol 1.28
    propionic acid 0.59
    o-xylene 0.12
    formic acid 65.37
    diethyl ether 0.14
    m-xylene 0.08
    p-xylene 0.03
    chlorobenzene 0.01
    dimethyl carbonate 0.66
    n-octane 0.06
    formamide 52.51
    cyclopentanone 0.53
    2-pentanone 0.18
    anisole 0.06
    cyclopentyl methyl ether 0.38
    gamma-butyrolactone 0.78
    1-methoxy-2-propanol 4.7
    pyridine 0.2
    3-pentanone 0.2
    furfural 1.33
    n-dodecane 0.02
    diethylene glycol 9.35
    diisopropyl ether 0.06
    tert-amyl alcohol 0.27
    acetylacetone 0.46
    n-hexadecane 0.02
    acetophenone 0.14
    methyl propionate 0.35
    isopentyl acetate 0.05
    trichloroethylene 0.13
    n-nonanol 0.17
    cyclohexanol 0.35
    benzyl alcohol 0.16
    2-ethylhexanol 0.11
    isooctanol 0.14
    dipropyl ether 0.24
    1,2-dichlorobenzene 0.03
    ethyl lactate 0.48
    propylene carbonate 0.28
    n-methylformamide 6.73
    2-pentanol 0.17
    n-pentane 0.07
    1-propoxy-2-propanol 1.2
    1-methoxy-2-propyl acetate 0.46
    2-(2-methoxypropoxy) propanol 1.03
    mesitylene 0.09
    ε-caprolactone 0.34
    p-cymene 0.07
    epichlorohydrin 0.39
    1,1,1-trichloroethane 0.03
    2-aminoethanol 9.86
    morpholine-4-carbaldehyde 9.88
    sulfolane 11.73
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.18
    n-hexyl acetate 0.1
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 1.69
    sec-butyl acetate 0.03
    tert-butyl acetate 0.13
    decalin 0.03
    glycerin 39.97
    diglyme 3.16
    acrylic acid 1.34
    isopropyl myristate 0.04
    n-butyric acid 0.41
    acetyl acetate 0.13
    di(2-ethylhexyl) phthalate 0.08
    ethyl propionate 0.1
    nitromethane 2.7
    1,2-diethoxyethane 0.21
    benzonitrile 0.03
    trioctyl phosphate 0.11
    1-bromopropane 0.06
    gamma-valerolactone 1.69
    n-decanol 0.12
    triethyl phosphate 0.2
    4-methyl-2-pentanol 0.09
    propionitrile 0.05
    vinylene carbonate 0.25
    1,1,2-trichlorotrifluoroethane 4.46
    DMS 0.21
    cumene 0.04
    2-octanol 0.12
    2-hexanone 0.06
    octyl acetate 0.06
    limonene 0.12
    1,2-dimethoxyethane 1.28
    ethyl orthosilicate 0.17
    tributyl phosphate 0.08
    diacetone alcohol 1.03
    N,N-dimethylaniline 0.21
    acrylonitrile 0.12
    aniline 0.13
    1,3-propanediol 4.84
    bromobenzene 0.01
    dibromomethane 0.07
    1,1,2,2-tetrachloroethane 0.23
    2-methyl-cyclohexyl acetate 0.07
    tetrabutyl urea 0.26
    diisobutyl methanol 0.12
    2-phenylethanol 0.17
    styrene 0.03
    dioctyl adipate 0.07
    dimethyl sulfate 4.5
    ethyl butyrate 0.11
    methyl lactate 2.84
    butyl lactate 0.41
    diethyl carbonate 0.07
    propanediol butyl ether 1.79
    triethyl orthoformate 0.17
    p-tert-butyltoluene 0.09
    methyl 4-tert-butylbenzoate 0.48
    morpholine 0.91
    tert-butylamine 0.14
    n-dodecanol 0.09
    dimethoxymethane 3.41
    ethylene carbonate 0.17
    cyrene 2.19
    2-ethoxyethyl acetate 0.2
    2-ethylhexyl acetate 0.04
    1,2,4-trichlorobenzene 0.04
    4-methylpyridine 0.11
    dibutyl ether 0.08
    2,6-dimethyl-4-heptanol 0.12
    DEF 1.32
    dimethyl isosorbide 1.42
    tetrachloroethylene 0.32
    eugenol 0.61
    triacetin 0.29
    span 80 1.02
    1,4-butanediol 1.42
    1,1-dichloroethane 0.03
    2-methyl-1-pentanol 0.07
    methyl formate 2.74
    2-methyl-1-butanol 0.13
    n-decane 0.04
    butyronitrile 0.04
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.05
    1-chlorotetradecane 0.02
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.01
    cyclooctane 0.09
    cyclopentanol 0.42
    tetrahydropyran 0.16
    tert-amyl methyl ether 0.12
    2,5,8-trioxanonane 2.66
    1-hexene 0.04
    2-isopropoxyethanol 0.62
    2,2,2-trifluoroethanol 4.21
    methyl butyrate 0.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction