Cellulase

Overview IFRA Request a quote

  • Identifiers

    CAS number
    9012-54-8

    Molecular formula
    C18H32O16

    SMILES
    C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)O)O

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 74.49%
    Sweet 44.75%
    Alcoholic 23.09%
    Caramellic 19.41%
    Woody 18.48%
    Clean 16.15%
    Cooling 16.1%
    Savory 15.53%
    Milky 15.43%
    Vanilla 15.3%

     

    Flavor
    Sweet 79.91%
    Odorless 55.8%
    Bitter 44.97%
    Sweet-like 32.56%
    Fatty 22.63%
    Cauliflower 22.08%
    Very slight 21.85%
    Soup 20.45%
    Alkaline 20.43%
    Mentholic 19.83%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -6.9

    pKa est.
    3.18 (weak acid)

    Molecular weight
    504.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    4746°C

    Flash point

    • 290.52 ˚C est.

  • Synonyms

    • Cellulase
    • 9012-54-8
    • (2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • Endo-1,4-beta-Glucanase
    • Cellulysin
    • Endoglucanase
    • (2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-((2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxyoxan-3-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol
    • RefChem:388872
    • GlyTouCan:G14338VK
    • Endo 1,4 beta Glucanase
    • Cellulase, aspergillus niger
    • Cellulase, trichoderma viride
    • DTXSID2049638
    • G14338VK
    • beta 1,4 Glucan 4 Glucanohydrolase
    • beta-1,4-Glucan-4-Glucanohydrolase
    • 7Q170212NX
    • EC 3.2.1.4
    • 1,4-(1,3;1,4)-beta-D-Glucan-4-glucanohydrolase
    • 232-734-4
    • beta-cellotriose
    • Cellulase from Trichoderma reesei
    • Cellulase from Trichoderma reesei ATCC 26921
    • Fungalcellulase
    • Cellulase, enzyme blend
    • Cellulase(Carrier for dextrine)
    • CHEBI:41753
    • FYGDTMLNYKFZSV-CSHPIKHBSA-N
    • MFCD00081510
    • DB01697
    • DA-51762
    • NS00070416
    • Cellulase from Aspergillus niger(Carrier for starch)
    • Q26840894
    • Beta-D-Glucopyranosyl-(1->4)-Beta-D-Glucopyranosyl-(1->4)-Beta-D-Glucopyranose
    • (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-2-(hydroxymethyl)-4,5,6-tris(oxidanyl)oxan-3-yl]oxy-4,5-bis(oxidanyl)oxan-3-yl]oxy-oxane-3,4,5-triol
    • 9012-54-8

  • Applications

    Cellulase (CAS 9012-54-8) is an enzyme that catalyzes the hydrolysis of cellulose and is used across several industrial sectors. In household cleaning, it is employed as a detergent additive to help remove plant-based soils. In textile processing, cellulase enables bio-polishing of cotton fabrics by preferentially removing microfibrils and improving hand feel. In the paper and pulp industry, it supports fiber modification, deinking, and gentle biobleaching steps to enhance pulp quality. In bioconversion, cellulase is a key component of enzymatic saccharification processes that convert cellulose to glucose for subsequent fermentation to biofuels or biochemicals. In food processing, it can aid juice and puree clarification and improve yield from plant materials. In agriculture, cellulase-based feed additives may enhance the digestibility of high-cellulose ingredients in animal diets. Subject to formulation and regulatory limits, these applications reflect typical use-cases.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.79
    methanol 17.07
    isopropanol 1.22
    water 83.71
    ethyl acetate 0.61
    n-propanol 1.96
    acetone 1.44
    n-butanol 1.24
    acetonitrile 0.7
    DMF 40.1
    toluene 0.25
    isobutanol 0.54
    1,4-dioxane 3.39
    methyl acetate 0.61
    THF 3.6
    2-butanone 0.85
    n-pentanol 0.5
    sec-butanol 0.73
    n-hexane 0.03
    ethylene glycol 27.96
    NMP 45.09
    cyclohexane 0.15
    DMSO 149.38
    n-butyl acetate 0.29
    n-octanol 0.56
    chloroform 0.18
    n-propyl acetate 0.22
    acetic acid 19.07
    dichloromethane 0.27
    cyclohexanone 1.89
    propylene glycol 14.68
    isopropyl acetate 0.32
    DMAc 27.03
    2-ethoxyethanol 7.58
    isopentanol 0.44
    n-heptane 0.12
    ethyl formate 1.06
    1,2-dichloroethane 0.34
    n-hexanol 0.49
    2-methoxyethanol 27.32
    isobutyl acetate 0.08
    tetrachloromethane 0.09
    n-pentyl acetate 0.44
    transcutol 11.66
    n-heptanol 0.73
    ethylbenzene 0.08
    MIBK 0.28
    2-propoxyethanol 5.21
    tert-butanol 0.52
    MTBE 0.18
    2-butoxyethanol 4.19
    propionic acid 2.98
    o-xylene 0.25
    formic acid 115.41
    diethyl ether 0.51
    m-xylene 0.17
    p-xylene 0.07
    chlorobenzene 0.08
    dimethyl carbonate 2.48
    n-octane 0.07
    formamide 83.56
    cyclopentanone 3.05
    2-pentanone 0.78
    anisole 0.22
    cyclopentyl methyl ether 1.31
    gamma-butyrolactone 5.09
    1-methoxy-2-propanol 11.6
    pyridine 1.78
    3-pentanone 0.71
    furfural 6.65
    n-dodecane 0.04
    diethylene glycol 14.96
    diisopropyl ether 0.11
    tert-amyl alcohol 0.5
    acetylacetone 1.66
    n-hexadecane 0.04
    acetophenone 0.52
    methyl propionate 1.49
    isopentyl acetate 0.18
    trichloroethylene 0.45
    n-nonanol 0.54
    cyclohexanol 1.16
    benzyl alcohol 0.71
    2-ethylhexanol 0.22
    isooctanol 0.37
    dipropyl ether 0.51
    1,2-dichlorobenzene 0.08
    ethyl lactate 1.2
    propylene carbonate 1.59
    n-methylformamide 17.73
    2-pentanol 0.5
    n-pentane 0.07
    1-propoxy-2-propanol 2.72
    1-methoxy-2-propyl acetate 1.38
    2-(2-methoxypropoxy) propanol 2.8
    mesitylene 0.11
    ε-caprolactone 2.16
    p-cymene 0.12
    epichlorohydrin 2.27
    1,1,1-trichloroethane 0.07
    2-aminoethanol 18.48
    morpholine-4-carbaldehyde 32.0
    sulfolane 22.57
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 1.14
    n-hexyl acetate 0.45
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 5.03
    sec-butyl acetate 0.12
    tert-butyl acetate 0.29
    decalin 0.03
    glycerin 53.43
    diglyme 8.42
    acrylic acid 6.97
    isopropyl myristate 0.16
    n-butyric acid 2.2
    acetyl acetate 0.59
    di(2-ethylhexyl) phthalate 0.33
    ethyl propionate 0.3
    nitromethane 14.07
    1,2-diethoxyethane 1.04
    benzonitrile 0.26
    trioctyl phosphate 0.32
    1-bromopropane 0.13
    gamma-valerolactone 12.09
    n-decanol 0.38
    triethyl phosphate 0.36
    4-methyl-2-pentanol 0.17
    propionitrile 0.35
    vinylene carbonate 1.8
    1,1,2-trichlorotrifluoroethane 10.45
    DMS 0.76
    cumene 0.05
    2-octanol 0.36
    2-hexanone 0.24
    octyl acetate 0.33
    limonene 0.22
    1,2-dimethoxyethane 3.53
    ethyl orthosilicate 0.31
    tributyl phosphate 0.23
    diacetone alcohol 1.8
    N,N-dimethylaniline 0.34
    acrylonitrile 0.85
    aniline 0.85
    1,3-propanediol 12.95
    bromobenzene 0.05
    dibromomethane 0.15
    1,1,2,2-tetrachloroethane 0.47
    2-methyl-cyclohexyl acetate 0.25
    tetrabutyl urea 0.64
    diisobutyl methanol 0.15
    2-phenylethanol 0.57
    styrene 0.08
    dioctyl adipate 0.38
    dimethyl sulfate 8.78
    ethyl butyrate 0.32
    methyl lactate 7.2
    butyl lactate 1.19
    diethyl carbonate 0.23
    propanediol butyl ether 5.56
    triethyl orthoformate 0.45
    p-tert-butyltoluene 0.12
    methyl 4-tert-butylbenzoate 1.2
    morpholine 6.51
    tert-butylamine 0.19
    n-dodecanol 0.26
    dimethoxymethane 8.77
    ethylene carbonate 1.28
    cyrene 5.86
    2-ethoxyethyl acetate 1.18
    2-ethylhexyl acetate 0.15
    1,2,4-trichlorobenzene 0.14
    4-methylpyridine 0.83
    dibutyl ether 0.27
    2,6-dimethyl-4-heptanol 0.15
    DEF 3.78
    dimethyl isosorbide 3.87
    tetrachloroethylene 0.5
    eugenol 1.48
    triacetin 1.33
    span 80 3.0
    1,4-butanediol 3.87
    1,1-dichloroethane 0.1
    2-methyl-1-pentanol 0.21
    methyl formate 8.85
    2-methyl-1-butanol 0.51
    n-decane 0.07
    butyronitrile 0.3
    3,7-dimethyl-1-octanol 0.21
    1-chlorooctane 0.14
    1-chlorotetradecane 0.05
    n-nonane 0.07
    undecane 0.05
    tert-butylcyclohexane 0.01
    cyclooctane 0.09
    cyclopentanol 1.69
    tetrahydropyran 1.13
    tert-amyl methyl ether 0.31
    2,5,8-trioxanonane 6.48
    1-hexene 0.05
    2-isopropoxyethanol 2.12
    2,2,2-trifluoroethanol 12.38
    methyl butyrate 0.4

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction