Calcium Phosphate

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  • Identifiers

    CAS number
    7758-87-4

    Molecular formula
    Ca3O8P2

    SMILES
    [O-]P(=O)([O-])[O-].[O-]P(=O)([O-])[O-].[Ca+2].[Ca+2].[Ca+2]

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Odorless 79.98%
    Sweet 22.72%
    Clean 16.66%
    Bitter 13.19%
    Sour 13.14%
    Balsamic 12.85%
    Musk 12.74%
    Savory 12.49%
    Fatty 11.66%
    Milky 11.57%

     

    Flavor
    Odorless 63.42%
    Sour 24.49%
    Bland 21.59%
    Mousy 19.92%
    Formyl 19.45%
    Rotten 18.9%
    Soy 18.72%
    Mild 18.72%
    Yeast 18.21%
    Stinky 17.92%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    -2.53 (strong acid)

    Molecular weight
    310.18 g/mol

    Melting point expt.

    • >450
    • 1670 °C

    Flash point

    • 97.91 ˚C est.

    Solubility expt.

    • 7.7g/L
    • Practically insol in alcohol and acetic acid; sol in dilute hydrochloric acid, nitric acid
    • Solubility in cold water: 2 mg/100 cc
    • 2.5 mg/100 g water at 25 °C

  • Synonyms

    • Calcium phosphate
    • 7758-87-4
    • TRICALCIUM PHOSPHATE
    • Synthos
    • Tricalcium diphosphate
    • Calcium orthophosphate
    • Tricalcium orthophosphate
    • Phosphoric acid, calcium salt (2:3)
    • 10103-46-5
    • Tertiary calcium phosphate
    • Calcigenol simple
    • beta-TCP
    • Phosphoric acid, calcium salt
    • beta-Tricalcium phosphate
    • Calcium tertiary phosphate
    • Calcium phosphate (3:2)
    • tricalcium;diphosphate
    • FEMA No. 3081
    • tricalcium bis(phosphate)
    • alpha-Tricalcium phosphate
    • Calciresorb;TCP
    • UNII-97Z1WI3NDX
    • Calcium phosphates
    • EINECS 233-283-6
    • 97Z1WI3NDX
    • INS NO.341(III)
    • AI3-25607
    • CHEBI:9679
    • INS-341(III)
    • E-341(III)
    • K4C08XP666
    • Bonarka
    • Calciumphosphate
    • Natural whitlockite
    • tri-calcium phosphate
    • Ceredex
    • Vitoss
    • 21063-37-6
    • Calcium phosphate (Ca3(PO4)2)
    • Calcium orthophosphate, tri-(tert)
    • Tricalcium phosphate (Ca3(PO4)2)
    • MFCD00015984
    • calcio fosfato
    • Tricalcium bis(orthophosphate)
    • Phosphoric acid calcium(2+) salt (2:3)
    • Ca3(PO4)2
    • calcium-phosphate
    • alpha-TCP
    • tricalciumphosphate
    • Posture (TN)
    • CALCIGENOL
    • beta tricalcium phosphate
    • TRICALCII PHOSPHAS
    • CALCIUM PHOSPHATE (II)
    • CHEMBL2106566
    • DTXSID1049803
    • CHEBI:77635
    • DTXSID40893099
    • CALCIUM PHOSPHATE (MART.)
    • CALCIUM PHOSPHATE [WHO-DD]
    • TRICALCIUM PHOSPHATE [FHFI]
    • PRECIPITATED CALCIUM PHOSPHATE
    • AKOS015833108
    • Phosphoric acid, calcium salt (1:?)
    • CALCIUM PHOSPHATE (EP IMPURITY)
    • CX-0072
    • DB11348
    • FC41082
    • CALCIUM PHOSPHATE (EP MONOGRAPH)
    • CALCIUM PHOSPHATE, TRIBASIC [MI]
    • Calcium phosphate, tribasic (ca.37% Ca)
    • CALCIUM PHOSPHATE, TRIBASIC [HSDB]
    • CALCIUM PHOSPHATE, UNSPECIFIED FORM
    • CALCIUM PHOSPHATE,ANHYDROUS [VANDF]
    • DB-230078
    • C3736
    • CS-0013475
    • NS00082557
    • C08136
    • D00938
    • Q278387
    • Calcium phosphate, Reagent for transient & stable DNA transfections
    • Tricalcium phosphate hydrate, nanopowder, <200 nm particle size (BET)
    • alpha-tri-Calcium phosphate, puriss. p.a., >=75% alpha-phase basis (sinterted powder)
    • alpha-tri-Calcium phosphate, Reagent for transient & stable DNA transfections
    • beta-tri-Calcium phosphate, puriss. p.a., >=95% beta-phase basis (sintered powder)
    • beta-tri-Calcium phosphate, puriss. p.a., >=98% beta-phase basis (sintered Powder)
    • beta-tri-Calcium phosphate, puriss. p.a., >=98% beta-phase basis (unsintered powder)
    • 233-283-6

  • Applications

    Calcium Phosphate (CAS 7758-87-4) has diverse applications across pharmaceuticals, agriculture, food processing, cosmetics, and biomedical fields. In pharmaceuticals, it serves as an inert excipient, a binder in tablets, and a calcium supplement. In agriculture, it is used as a calcium and phosphorus source in fertilizers. In food processing, it functions as a dietary calcium fortificant and is sometimes employed as a leavening agent in baking powders. In cosmetics and personal care, it can act as an abrasive or texturizing filler in products such as toothpaste. In biomedicine, calcium phosphate materials are studied and used as biocompatible ceramics and coatings for bone repair and dental implants.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 355.28
    methanol 584.21
    isopropanol 301.76
    water 400.4
    ethyl acetate 69.93
    n-propanol 227.35
    acetone 249.16
    n-butanol 187.91
    acetonitrile 126.85
    DMF 820.69
    toluene 34.34
    isobutanol 141.23
    1,4-dioxane 167.59
    methyl acetate 89.37
    THF 301.88
    2-butanone 121.37
    n-pentanol 115.15
    sec-butanol 195.1
    n-hexane 30.21
    ethylene glycol 352.42
    NMP 314.91
    cyclohexane 42.37
    DMSO 949.44
    n-butyl acetate 38.44
    n-octanol 78.59
    chloroform 65.7
    n-propyl acetate 45.25
    acetic acid 130.31
    dichloromethane 92.17
    cyclohexanone 88.08
    propylene glycol 210.2
    isopropyl acetate 55.27
    DMAc 432.69
    2-ethoxyethanol 238.15
    isopentanol 129.52
    n-heptane 32.28
    ethyl formate 84.8
    1,2-dichloroethane 99.46
    n-hexanol 99.2
    2-methoxyethanol 525.33
    isobutyl acetate 21.3
    tetrachloromethane 29.5
    n-pentyl acetate 43.91
    transcutol 167.16
    n-heptanol 76.03
    ethylbenzene 19.28
    MIBK 71.42
    2-propoxyethanol 193.17
    tert-butanol 316.04
    MTBE 150.49
    2-butoxyethanol 121.33
    propionic acid 97.1
    o-xylene 38.0
    formic acid 267.36
    diethyl ether 187.24
    m-xylene 32.81
    p-xylene 21.63
    chlorobenzene 21.06
    dimethyl carbonate 89.67
    n-octane 18.01
    formamide 393.48
    cyclopentanone 134.43
    2-pentanone 116.23
    anisole 47.62
    cyclopentyl methyl ether 131.54
    gamma-butyrolactone 133.04
    1-methoxy-2-propanol 350.27
    pyridine 80.82
    3-pentanone 87.58
    furfural 124.44
    n-dodecane 12.8
    diethylene glycol 251.34
    diisopropyl ether 61.48
    tert-amyl alcohol 204.04
    acetylacetone 89.61
    n-hexadecane 13.18
    acetophenone 44.67
    methyl propionate 97.43
    isopentyl acetate 29.28
    trichloroethylene 67.33
    n-nonanol 69.33
    cyclohexanol 121.38
    benzyl alcohol 59.61
    2-ethylhexanol 47.07
    isooctanol 51.57
    dipropyl ether 77.92
    1,2-dichlorobenzene 22.04
    ethyl lactate 54.05
    propylene carbonate 54.54
    n-methylformamide 342.16
    2-pentanol 158.58
    n-pentane 68.4
    1-propoxy-2-propanol 127.47
    1-methoxy-2-propyl acetate 54.32
    2-(2-methoxypropoxy) propanol 84.06
    mesitylene 29.08
    ε-caprolactone 65.78
    p-cymene 21.31
    epichlorohydrin 134.77
    1,1,1-trichloroethane 40.79
    2-aminoethanol 318.07
    morpholine-4-carbaldehyde 257.94
    sulfolane 218.97
    2,2,4-trimethylpentane 18.28
    2-methyltetrahydrofuran 147.18
    n-hexyl acetate 50.79
    isooctane 16.45
    2-(2-butoxyethoxy)ethanol 114.46
    sec-butyl acetate 27.84
    tert-butyl acetate 61.41
    decalin 10.91
    glycerin 318.81
    diglyme 171.98
    acrylic acid 96.9
    isopropyl myristate 31.18
    n-butyric acid 88.56
    acetyl acetate 34.05
    di(2-ethylhexyl) phthalate 27.33
    ethyl propionate 47.99
    nitromethane 192.78
    1,2-diethoxyethane 72.45
    benzonitrile 33.4
    trioctyl phosphate 29.84
    1-bromopropane 69.54
    gamma-valerolactone 148.87
    n-decanol 57.22
    triethyl phosphate 28.02
    4-methyl-2-pentanol 80.45
    propionitrile 90.66
    vinylene carbonate 49.54
    1,1,2-trichlorotrifluoroethane 129.17
    DMS 35.99
    cumene 17.42
    2-octanol 61.11
    2-hexanone 57.5
    octyl acetate 39.88
    limonene 31.62
    1,2-dimethoxyethane 271.21
    ethyl orthosilicate 29.34
    tributyl phosphate 26.45
    diacetone alcohol 115.22
    N,N-dimethylaniline 64.8
    acrylonitrile 101.69
    aniline 70.68
    1,3-propanediol 289.12
    bromobenzene 15.56
    dibromomethane 76.14
    1,1,2,2-tetrachloroethane 84.65
    2-methyl-cyclohexyl acetate 27.36
    tetrabutyl urea 48.14
    diisobutyl methanol 39.96
    2-phenylethanol 50.93
    styrene 20.49
    dioctyl adipate 34.23
    dimethyl sulfate 147.35
    ethyl butyrate 36.61
    methyl lactate 120.02
    butyl lactate 44.78
    diethyl carbonate 25.42
    propanediol butyl ether 100.7
    triethyl orthoformate 33.73
    p-tert-butyltoluene 24.97
    methyl 4-tert-butylbenzoate 64.34
    morpholine 209.99
    tert-butylamine 209.02
    n-dodecanol 46.59
    dimethoxymethane 433.27
    ethylene carbonate 45.61
    cyrene 74.57
    2-ethoxyethyl acetate 48.34
    2-ethylhexyl acetate 23.43
    1,2,4-trichlorobenzene 24.94
    4-methylpyridine 75.0
    dibutyl ether 48.37
    2,6-dimethyl-4-heptanol 39.96
    DEF 171.93
    dimethyl isosorbide 91.38
    tetrachloroethylene 72.23
    eugenol 73.05
    triacetin 40.81
    span 80 69.9
    1,4-butanediol 135.59
    1,1-dichloroethane 67.39
    2-methyl-1-pentanol 72.41
    methyl formate 222.93
    2-methyl-1-butanol 116.36
    n-decane 18.88
    butyronitrile 80.87
    3,7-dimethyl-1-octanol 51.2
    1-chlorooctane 35.38
    1-chlorotetradecane 18.91
    n-nonane 19.81
    undecane 15.13
    tert-butylcyclohexane 10.93
    cyclooctane 21.65
    cyclopentanol 154.27
    tetrahydropyran 123.4
    tert-amyl methyl ether 127.03
    2,5,8-trioxanonane 139.34
    1-hexene 45.4
    2-isopropoxyethanol 139.79
    2,2,2-trifluoroethanol 107.86
    methyl butyrate 56.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction