Bromodichloromethane

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  • Identifiers

    CAS number
    75-27-4

    Molecular formula
    CHBrCl2

    SMILES
    C(Cl)(Cl)Br

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 44.61%
    Fishy 37.07%
    Green 25.75%
    Cheesy 24.95%
    Ripe 22.05%
    Meaty 21.21%
    Oily 19.8%
    Musty 18.45%
    Sweet 18.45%
    Fruity 18.25%

     

    Flavor
    Odorless 34.12%
    Sulfurous 26.69%
    Fishy 25.94%
    Meaty 23.93%
    Sulfury 23.81%
    Ammoniacal 23.58%
    Glue 19.19%
    Bloody 19.01%
    Onion 18.51%
    Rotten 18.51%

     

    Odor impact est.
    High

    Odor threshold

    • Odor threshold low: 1680 mg/cu m odor high 1680 mg/cu m. /Bromochloromethane/

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    5.11 (weak acid)

    Molecular weight
    163.83 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -67 °F (NTP, 1992)
    • -57 °C

    Boiling point

    • 189 °F at 760 mmHg (NTP, 1992)
    • 90 °C

    Flash point

    • 24.33 ˚C est.

    Solubility expt.

    • 5 to 10 mg/mL at 66 °F (NTP, 1992)
    • Very soluble in ethanol, ethyl ether, benzene and acetone; slightly soluble in carbon tetrachloride.
    • Very soluble in organic solvents; miscible with chloroform
    • In water, 3.968X10+3 mg/L at 30 °C
    • Solubility in water, g/100ml at 20 °C: 0.45 (poor)

  • Synonyms

    • BROMODICHLOROMETHANE
    • 75-27-4
    • Dichlorobromomethane
    • Methane, bromodichloro-
    • bromo(dichloro)methane
    • Dichloromonobromomethane
    • Monobromodichloromethane
    • BDCM
    • CHBrCl2
    • NCI-C55243
    • NSC 8018
    • Bromodichlormethane
    • CCRIS 819
    • Bromo-Dichloro-Methane
    • HSDB 4160
    • EINECS 200-856-7
    • UNII-7LN464CH2O
    • BRN 1697005
    • 7LN464CH2O
    • DTXSID1020198
    • CHEBI:34591
    • AI3-18134
    • NSC-8018
    • DTXCID30198
    • BROMODICHLOROMETHANE [MI]
    • NSC8018
    • BROMODICHLOROMETHANE [HSDB]
    • BROMODICHLOROMETHANE [IARC]
    • 4-01-00-00076 (Beilstein Handbook Reference)
    • Bromodichloromethane 100 microg/mL in Methanol
    • BROMODICHLOROMETHANE (IARC)
    • dichloromethylbromide
    • Bromodichloromethane (stabilized with Ethanol)
    • Bromodichoromethane
    • MFCD00000824
    • methane, bromodichloro
    • WLN: GYGE
    • SCHEMBL75683
    • BIDD:ER0623
    • Bromodichloromethane, >=97%
    • CHEMBL346231
    • Tox21_200806
    • AKOS015902362
    • Bromodichloromethane, analytical standard
    • CAS-75-27-4
    • NCGC00091480-01
    • NCGC00091480-02
    • NCGC00258360-01
    • B1011
    • NS00007535
    • F17746
    • EN300-1702819
    • Q417426
    • Bromodichloromethane, amylene stabilized, analytical standard
    • 64 - Trihalomethanes (THMs) & Nutrients in Recreational Water
    • 103 - Trihalomethanes (THMs) & Nutrients in Recreational Water
    • 200-856-7

  • Applications

    Bromodichloromethane (CAS 75-27-4) is primarily used as a solvent and reaction medium in chemical manufacturing, and serves as an intermediate in the synthesis of other brominated compounds and specialty products. In laboratory settings, it is employed as an analytical solvent and a standard reagent for chromatography methods (GC/LC) and sample preparation. It is also considered a starting material or intermediate in routes to brominated chemicals and materials for polymers/plastics. It may be evaluated for research or pilot-scale development applications, all subject to safety considerations and local regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 93.53
    methanol 95.61
    isopropanol 86.61
    water 7.75
    ethyl acetate 129.73
    n-propanol 83.72
    acetone 299.62
    n-butanol 91.12
    acetonitrile 128.13
    DMF 442.9
    toluene 148.41
    isobutanol 74.58
    1,4-dioxane 321.44
    methyl acetate 151.16
    THF 413.45
    2-butanone 184.57
    n-pentanol 91.05
    sec-butanol 88.56
    n-hexane 43.71
    ethylene glycol 53.24
    NMP 535.49
    cyclohexane 85.35
    DMSO 491.9
    n-butyl acetate 143.66
    n-octanol 94.81
    chloroform 244.33
    n-propyl acetate 124.81
    acetic acid 155.36
    dichloromethane 247.34
    cyclohexanone 276.62
    propylene glycol 39.9
    isopropyl acetate 111.14
    DMAc 407.19
    2-ethoxyethanol 158.97
    isopentanol 89.02
    n-heptane 75.08
    ethyl formate 103.83
    1,2-dichloroethane 190.54
    n-hexanol 98.89
    2-methoxyethanol 205.14
    isobutyl acetate 97.87
    tetrachloromethane 92.12
    n-pentyl acetate 122.95
    transcutol 387.81
    n-heptanol 83.75
    ethylbenzene 91.6
    MIBK 133.83
    2-propoxyethanol 166.39
    tert-butanol 118.52
    MTBE 150.34
    2-butoxyethanol 129.96
    propionic acid 75.89
    o-xylene 137.38
    formic acid 71.71
    diethyl ether 163.65
    m-xylene 123.76
    p-xylene 119.79
    chlorobenzene 149.0
    dimethyl carbonate 105.33
    n-octane 36.68
    formamide 120.5
    cyclopentanone 326.87
    2-pentanone 175.29
    anisole 171.6
    cyclopentyl methyl ether 238.29
    gamma-butyrolactone 263.18
    1-methoxy-2-propanol 161.14
    pyridine 256.27
    3-pentanone 162.34
    furfural 312.56
    n-dodecane 29.68
    diethylene glycol 155.19
    diisopropyl ether 98.75
    tert-amyl alcohol 109.19
    acetylacetone 241.59
    n-hexadecane 32.95
    acetophenone 185.82
    methyl propionate 128.73
    isopentyl acetate 129.09
    trichloroethylene 312.08
    n-nonanol 90.98
    cyclohexanol 138.41
    benzyl alcohol 128.86
    2-ethylhexanol 97.03
    isooctanol 77.46
    dipropyl ether 165.01
    1,2-dichlorobenzene 144.16
    ethyl lactate 76.25
    propylene carbonate 144.32
    n-methylformamide 150.26
    2-pentanol 84.18
    n-pentane 52.21
    1-propoxy-2-propanol 155.65
    1-methoxy-2-propyl acetate 150.27
    2-(2-methoxypropoxy) propanol 152.96
    mesitylene 102.85
    ε-caprolactone 202.5
    p-cymene 101.8
    epichlorohydrin 266.31
    1,1,1-trichloroethane 192.24
    2-aminoethanol 64.26
    morpholine-4-carbaldehyde 421.55
    sulfolane 388.36
    2,2,4-trimethylpentane 37.85
    2-methyltetrahydrofuran 278.55
    n-hexyl acetate 130.2
    isooctane 30.65
    2-(2-butoxyethoxy)ethanol 182.12
    sec-butyl acetate 100.86
    tert-butyl acetate 141.48
    decalin 46.55
    glycerin 73.18
    diglyme 331.05
    acrylic acid 88.89
    isopropyl myristate 91.05
    n-butyric acid 96.82
    acetyl acetate 118.47
    di(2-ethylhexyl) phthalate 80.69
    ethyl propionate 112.46
    nitromethane 267.06
    1,2-diethoxyethane 216.52
    benzonitrile 149.54
    trioctyl phosphate 64.71
    1-bromopropane 119.66
    gamma-valerolactone 351.98
    n-decanol 78.17
    triethyl phosphate 89.58
    4-methyl-2-pentanol 68.86
    propionitrile 87.23
    vinylene carbonate 137.34
    1,1,2-trichlorotrifluoroethane 235.73
    DMS 114.68
    cumene 80.2
    2-octanol 75.17
    2-hexanone 160.37
    octyl acetate 97.87
    limonene 144.47
    1,2-dimethoxyethane 322.05
    ethyl orthosilicate 93.9
    tributyl phosphate 72.27
    diacetone alcohol 157.59
    N,N-dimethylaniline 179.14
    acrylonitrile 107.53
    aniline 141.34
    1,3-propanediol 88.31
    bromobenzene 151.83
    dibromomethane 176.87
    1,1,2,2-tetrachloroethane 248.33
    2-methyl-cyclohexyl acetate 124.66
    tetrabutyl urea 123.5
    diisobutyl methanol 90.53
    2-phenylethanol 124.57
    styrene 111.52
    dioctyl adipate 117.74
    dimethyl sulfate 182.94
    ethyl butyrate 140.14
    methyl lactate 90.8
    butyl lactate 94.34
    diethyl carbonate 95.94
    propanediol butyl ether 115.93
    triethyl orthoformate 120.7
    p-tert-butyltoluene 102.95
    methyl 4-tert-butylbenzoate 167.07
    morpholine 293.77
    tert-butylamine 94.04
    n-dodecanol 72.05
    dimethoxymethane 266.41
    ethylene carbonate 114.48
    cyrene 185.02
    2-ethoxyethyl acetate 149.02
    2-ethylhexyl acetate 122.0
    1,2,4-trichlorobenzene 175.8
    4-methylpyridine 241.14
    dibutyl ether 132.59
    2,6-dimethyl-4-heptanol 90.53
    DEF 244.11
    dimethyl isosorbide 273.92
    tetrachloroethylene 203.51
    eugenol 159.74
    triacetin 152.32
    span 80 144.1
    1,4-butanediol 59.57
    1,1-dichloroethane 154.56
    2-methyl-1-pentanol 88.14
    methyl formate 141.1
    2-methyl-1-butanol 83.34
    n-decane 41.42
    butyronitrile 100.08
    3,7-dimethyl-1-octanol 97.41
    1-chlorooctane 86.42
    1-chlorotetradecane 53.22
    n-nonane 41.75
    undecane 34.01
    tert-butylcyclohexane 42.87
    cyclooctane 48.38
    cyclopentanol 144.95
    tetrahydropyran 251.18
    tert-amyl methyl ether 149.27
    2,5,8-trioxanonane 271.91
    1-hexene 80.26
    2-isopropoxyethanol 140.49
    2,2,2-trifluoroethanol 100.01
    methyl butyrate 138.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Carob bean extract 1 9000-40-2 Ceratonia siliqua L., fam. Leguminoseae 0.1%