Sodium hypophosphite

Overview IFRA Request a quote

  • Identifiers

    CAS number
    7681-53-0

    Molecular formula
    NaO2P

    SMILES
    [O-]P=O.[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 84.31%
    Sharp 21.9%
    Pungent 21.46%
    Sour 20.66%
    Burnt 14.63%
    Cheesy 13.61%
    Caramellic 13.45%
    Ethereal 13.0%
    Fermented 11.78%
    Milky 11.59%

     

    Flavor
    Odorless 59.62%
    Pungent 37.13%
    Vinegar 31.75%
    Sour 30.65%
    Mustard 28.58%
    Formyl 26.4%
    Mousy 22.59%
    Rotten 21.67%
    Sulfur 21.67%
    Soy 21.34%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    -1.75 (strong acid)

    Molecular weight
    85.962 g/mol

    Melting point expt.

    • Melting point equals 392 °F (decomposes into toxic and explosive phosphine gas)
    • Decomposes above 238 °C (OECD Guideline 102)

    Flash point

    • 32.85 ˚C est.

    Solubility expt.

    • White, colorless, deliquescent granules; saline taste. Soluble in 1 part water, 0.15 part boiling water; freely soluble in glycerol and in boiling alcohol; soluble in cold alcohol, slightly soluble in absolute alcohol. Insoluble in ether. Solubility of anhydrous NaH2PO2 at 25 °C in ethylene glycol: 33.0 g/100g; in propylene glycol: 9.7 g/100g. /Sodium hypophosphite monohydrate/
    • In water, 909 g/L at 30 °C and pH 5.8 to 5.9
    • Soluble in water
    • Slightly soluble in alcohol
    • Slightly soluble in ammonia and ammonium hydroxide

  • Synonyms

    • SODIUM HYPOPHOSPHITE
    • Sodium phosphinate
    • 7681-53-0
    • 8TU1537O43
    • RefChem:887621
    • DTXCID701012093
    • 231-669-9
    • DTXSID30873901
    • Hypophosphorous acid monosodium salt
    • Monosodium hypophosphite
    • Natriumhypophosphit
    • Phosphinic acid monosodium salt
    • Phosphinic acid, sodium salt
    • Sodium hydrogen phosphite (NaH2PO2)
    • Sodium hydrophosphite
    • Sodium hypophosphite (NaH2PO2)
    • Sodium phosphinate (NaH2PO2)
    • Sodium phosphenite
    • NaO2P
    • sodium;oxido(oxo)phosphanium
    • SCHEMBL41451
    • CHEMBL2146115
    • SODIUM HYPOPHOSPHITE [MI]
    • CHEBI:234148
    • ZGKNDXOLMOFEJH-UHFFFAOYSA-M
    • SODIUM HYPOPHOSPHITE [FCC]
    • SODIUM HYPOPHOSPHITE [HSDB]
    • SODIUM HYPOPHOSPHITE [WHO-DD]
    • AKOS025244065
    • Q2090740
    • 7681-53-0

  • Applications

    Sodium hypophosphite is used primarily as a reducing agent in electroless nickel plating baths to deposit nickel-phosphorus (Ni-P) coatings on complex substrates. It also serves as a heat stabilizer in PVC and other polymers, helping improve thermal stability and reduce hydrochloric acid release at elevated temperatures. In specialty chemical synthesis, it acts as a source of hypophosphite for preparing phosphorus-containing intermediates. These applications are common in industrial manufacturing and surface-treatment formulations, and are subject to local regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1054.46
    methanol 1640.05
    isopropanol 916.66
    water 372.7
    ethyl acetate 264.71
    n-propanol 670.36
    acetone 955.92
    n-butanol 627.95
    acetonitrile 468.05
    DMF 3338.12
    toluene 97.61
    isobutanol 451.95
    1,4-dioxane 672.73
    methyl acetate 350.86
    THF 1172.71
    2-butanone 449.27
    n-pentanol 429.7
    sec-butanol 587.24
    n-hexane 56.41
    ethylene glycol 846.09
    NMP 1022.42
    cyclohexane 53.18
    DMSO 2607.07
    n-butyl acetate 138.46
    n-octanol 224.79
    chloroform 198.24
    n-propyl acetate 181.87
    acetic acid 569.64
    dichloromethane 285.16
    cyclohexanone 311.19
    propylene glycol 578.81
    isopropyl acetate 183.21
    DMAc 1379.56
    2-ethoxyethanol 796.17
    isopentanol 460.53
    n-heptane 52.87
    ethyl formate 286.24
    1,2-dichloroethane 297.65
    n-hexanol 285.3
    2-methoxyethanol 1550.55
    isobutyl acetate 105.5
    tetrachloromethane 66.36
    n-pentyl acetate 152.52
    transcutol 795.08
    n-heptanol 210.91
    ethylbenzene 67.09
    MIBK 273.47
    2-propoxyethanol 600.66
    tert-butanol 1081.82
    MTBE 510.15
    2-butoxyethanol 398.4
    propionic acid 332.07
    o-xylene 99.36
    formic acid 696.27
    diethyl ether 528.53
    m-xylene 95.31
    p-xylene 71.14
    chlorobenzene 84.89
    dimethyl carbonate 291.85
    n-octane 30.12
    formamide 1026.28
    cyclopentanone 527.37
    2-pentanone 421.84
    anisole 224.02
    cyclopentyl methyl ether 433.99
    gamma-butyrolactone 498.41
    1-methoxy-2-propanol 1104.93
    pyridine 301.91
    3-pentanone 263.85
    furfural 488.13
    n-dodecane 29.69
    diethylene glycol 683.05
    diisopropyl ether 174.96
    tert-amyl alcohol 649.45
    acetylacetone 348.05
    n-hexadecane 30.57
    acetophenone 167.69
    methyl propionate 325.89
    isopentyl acetate 114.89
    trichloroethylene 279.61
    n-nonanol 200.91
    cyclohexanol 343.84
    benzyl alcohol 217.79
    2-ethylhexanol 137.92
    isooctanol 153.77
    dipropyl ether 211.33
    1,2-dichlorobenzene 84.09
    ethyl lactate 172.4
    propylene carbonate 199.16
    n-methylformamide 1160.39
    2-pentanol 482.72
    n-pentane 102.08
    1-propoxy-2-propanol 408.15
    1-methoxy-2-propyl acetate 185.45
    2-(2-methoxypropoxy) propanol 297.07
    mesitylene 76.39
    ε-caprolactone 242.34
    p-cymene 52.66
    epichlorohydrin 595.59
    1,1,1-trichloroethane 157.76
    2-aminoethanol 864.71
    morpholine-4-carbaldehyde 930.56
    sulfolane 665.72
    2,2,4-trimethylpentane 41.28
    2-methyltetrahydrofuran 557.87
    n-hexyl acetate 185.16
    isooctane 42.0
    2-(2-butoxyethoxy)ethanol 454.23
    sec-butyl acetate 117.32
    tert-butyl acetate 236.07
    decalin 27.31
    glycerin 839.01
    diglyme 680.17
    acrylic acid 346.02
    isopropyl myristate 104.33
    n-butyric acid 320.87
    acetyl acetate 134.18
    di(2-ethylhexyl) phthalate 90.51
    ethyl propionate 173.26
    nitromethane 885.81
    1,2-diethoxyethane 291.95
    benzonitrile 154.6
    trioctyl phosphate 87.46
    1-bromopropane 186.52
    gamma-valerolactone 624.45
    n-decanol 166.53
    triethyl phosphate 72.39
    4-methyl-2-pentanol 265.59
    propionitrile 313.96
    vinylene carbonate 183.52
    1,1,2-trichlorotrifluoroethane 443.11
    DMS 131.42
    cumene 54.42
    2-octanol 177.76
    2-hexanone 236.7
    octyl acetate 138.24
    limonene 81.21
    1,2-dimethoxyethane 1008.49
    ethyl orthosilicate 74.47
    tributyl phosphate 86.75
    diacetone alcohol 414.77
    N,N-dimethylaniline 214.1
    acrylonitrile 385.41
    aniline 210.16
    1,3-propanediol 869.04
    bromobenzene 66.51
    dibromomethane 194.95
    1,1,2,2-tetrachloroethane 261.05
    2-methyl-cyclohexyl acetate 88.63
    tetrabutyl urea 154.42
    diisobutyl methanol 118.99
    2-phenylethanol 172.58
    styrene 83.32
    dioctyl adipate 124.58
    dimethyl sulfate 465.21
    ethyl butyrate 118.65
    methyl lactate 336.4
    butyl lactate 151.62
    diethyl carbonate 78.76
    propanediol butyl ether 368.73
    triethyl orthoformate 98.75
    p-tert-butyltoluene 61.32
    methyl 4-tert-butylbenzoate 195.68
    morpholine 826.93
    tert-butylamine 633.7
    n-dodecanol 137.18
    dimethoxymethane 1344.49
    ethylene carbonate 164.62
    cyrene 243.29
    2-ethoxyethyl acetate 189.04
    2-ethylhexyl acetate 85.37
    1,2,4-trichlorobenzene 99.8
    4-methylpyridine 299.29
    dibutyl ether 165.19
    2,6-dimethyl-4-heptanol 118.99
    DEF 637.25
    dimethyl isosorbide 343.41
    tetrachloroethylene 211.29
    eugenol 255.89
    triacetin 149.95
    span 80 259.51
    1,4-butanediol 433.91
    1,1-dichloroethane 231.38
    2-methyl-1-pentanol 292.57
    methyl formate 777.81
    2-methyl-1-butanol 406.13
    n-decane 39.13
    butyronitrile 306.43
    3,7-dimethyl-1-octanol 161.96
    1-chlorooctane 96.11
    1-chlorotetradecane 54.59
    n-nonane 37.33
    undecane 33.66
    tert-butylcyclohexane 29.8
    cyclooctane 28.65
    cyclopentanol 462.39
    tetrahydropyran 443.83
    tert-amyl methyl ether 395.83
    2,5,8-trioxanonane 551.68
    1-hexene 134.53
    2-isopropoxyethanol 488.2
    2,2,2-trifluoroethanol 320.16
    methyl butyrate 232.08

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction