Sodium Glycinate

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  • Identifiers

    CAS number
    6000-44-8

    Molecular formula
    C2H4NNaO2

    SMILES
    C(C(=O)[O-])N.[Na+]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 79.19%
    Sweet 24.32%
    Fishy 18.92%
    Savory 18.91%
    Buttery 14.43%
    Caramellic 13.58%
    Meaty 13.06%
    Cooked 12.88%
    Milky 12.56%
    Sour 12.3%

     

    Flavor
    Odorless 63.93%
    Sour 26.48%
    Mild 26.43%
    Acidic 21.73%
    Faint 21.15%
    Mousy 21.07%
    Yeast 21.01%
    Bland 20.63%
    Very mild 20.22%
    Sweet-like 19.85%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.24 (weak acid)

    Molecular weight
    97.05 g/mol

    Flash point

    • 89.43 ˚C est.

  • Synonyms

    • Sodium glycinate
    • Glycine, monosodium salt
    • Sodium glycine
    • Sodium aminoacetate
    • Sodium glycocollate
    • Glycine, sodium salt (1:1)
    • F6B979BV8Z
    • ORISTAR SGLY
    • DTXSID50884211
    • RefChem:183897
    • DTXCID701023666
    • 227-842-3
    • 6000-44-8
    • sodium 2-aminoacetate
    • Glycine sodium salt
    • sodium;2-aminoacetate
    • GLYCINE, SODIUM SALT
    • MFCD00062543
    • Sodum glycinate
    • EINECS 227-842-3
    • C2H4NNaO2
    • UNII-F6B979BV8Z
    • Glycine Sodium Hydrate
    • H2NCH2COONa
    • sodium 2-azanylethanoate
    • SCHEMBL27196
    • Glycine sodium salt anhydrous
    • Aminoacetic acid;Aminoethanoic acid
    • AKOS001127703
    • CS-W016662
    • HY-W015946
    • AS-12443
    • DA-57973
    • NS00082765
    • EN300-18908
    • D70403
    • G-4900
    • A832567
    • F240909
    • Q27277708
    • 6000-44-8

  • Applications

    Sodium Glycinate, CAS 6000-44-8, is used as a buffering agent and metal chelating agent in cosmetic and personal care formulations, helping to stabilize pH and mitigate metal-catalyzed degradation. It also serves as a source of glycine for chemical synthesis and can function as an intermediate in industrial manufacturing processes, including polymers and plastics, where it may act as a processing aid or stabilizer. In household cleaners, it can aid metal ion sequestration, improving formulation stability and performance. It is sometimes evaluated as an excipient in pharmaceutical formulations and may be used as a component in various formulation additives, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.86
    methanol 27.55
    isopropanol 5.33
    water 148.94
    ethyl acetate 1.58
    n-propanol 5.46
    acetone 9.67
    n-butanol 4.68
    acetonitrile 5.63
    DMF 91.7
    toluene 0.69
    isobutanol 3.7
    1,4-dioxane 6.98
    methyl acetate 3.59
    THF 5.07
    2-butanone 4.2
    n-pentanol 3.09
    sec-butanol 3.78
    n-hexane 0.38
    ethylene glycol 24.07
    NMP 77.78
    cyclohexane 0.47
    DMSO 133.13
    n-butyl acetate 2.11
    n-octanol 2.14
    chloroform 0.98
    n-propyl acetate 1.46
    acetic acid 33.75
    dichloromethane 2.18
    cyclohexanone 7.68
    propylene glycol 13.15
    isopropyl acetate 1.19
    DMAc 68.9
    2-ethoxyethanol 13.01
    isopentanol 4.22
    n-heptane 0.45
    ethyl formate 8.26
    1,2-dichloroethane 2.42
    n-hexanol 2.48
    2-methoxyethanol 26.61
    isobutyl acetate 0.75
    tetrachloromethane 0.38
    n-pentyl acetate 2.24
    transcutol 25.92
    n-heptanol 2.28
    ethylbenzene 0.64
    MIBK 1.96
    2-propoxyethanol 7.93
    tert-butanol 6.7
    MTBE 2.57
    2-butoxyethanol 7.75
    propionic acid 10.49
    o-xylene 1.41
    formic acid 84.59
    diethyl ether 1.37
    m-xylene 0.81
    p-xylene 1.05
    chlorobenzene 0.84
    dimethyl carbonate 3.14
    n-octane 0.25
    formamide 73.99
    cyclopentanone 8.03
    2-pentanone 2.71
    anisole 2.1
    cyclopentyl methyl ether 1.99
    gamma-butyrolactone 12.8
    1-methoxy-2-propanol 12.12
    pyridine 4.99
    3-pentanone 2.14
    furfural 27.63
    n-dodecane 0.19
    diethylene glycol 16.99
    diisopropyl ether 0.61
    tert-amyl alcohol 6.12
    acetylacetone 5.14
    n-hexadecane 0.2
    acetophenone 3.85
    methyl propionate 2.45
    isopentyl acetate 2.15
    trichloroethylene 2.71
    n-nonanol 1.99
    cyclohexanol 3.45
    benzyl alcohol 4.03
    2-ethylhexanol 1.73
    isooctanol 1.93
    dipropyl ether 1.22
    1,2-dichlorobenzene 1.27
    ethyl lactate 3.65
    propylene carbonate 6.61
    n-methylformamide 37.19
    2-pentanol 2.2
    n-pentane 0.37
    1-propoxy-2-propanol 5.33
    1-methoxy-2-propyl acetate 3.31
    2-(2-methoxypropoxy) propanol 11.88
    mesitylene 0.82
    ε-caprolactone 7.46
    p-cymene 1.0
    epichlorohydrin 6.98
    1,1,1-trichloroethane 0.65
    2-aminoethanol 20.28
    morpholine-4-carbaldehyde 49.92
    sulfolane 42.3
    2,2,4-trimethylpentane 0.31
    2-methyltetrahydrofuran 3.29
    n-hexyl acetate 2.6
    isooctane 0.17
    2-(2-butoxyethoxy)ethanol 13.01
    sec-butyl acetate 0.85
    tert-butyl acetate 1.77
    decalin 0.28
    glycerin 31.01
    diglyme 22.53
    acrylic acid 18.87
    isopropyl myristate 1.25
    n-butyric acid 7.3
    acetyl acetate 1.79
    di(2-ethylhexyl) phthalate 3.53
    ethyl propionate 1.33
    nitromethane 44.68
    1,2-diethoxyethane 3.61
    benzonitrile 3.16
    trioctyl phosphate 2.34
    1-bromopropane 0.85
    gamma-valerolactone 24.04
    n-decanol 1.63
    triethyl phosphate 2.24
    4-methyl-2-pentanol 1.59
    propionitrile 2.57
    vinylene carbonate 8.39
    1,1,2-trichlorotrifluoroethane 15.7
    DMS 3.23
    cumene 0.76
    2-octanol 1.51
    2-hexanone 1.95
    octyl acetate 1.91
    limonene 1.32
    1,2-dimethoxyethane 15.91
    ethyl orthosilicate 1.93
    tributyl phosphate 2.64
    diacetone alcohol 6.17
    N,N-dimethylaniline 3.5
    acrylonitrile 5.83
    aniline 2.39
    1,3-propanediol 17.36
    bromobenzene 0.58
    dibromomethane 1.24
    1,1,2,2-tetrachloroethane 2.55
    2-methyl-cyclohexyl acetate 2.16
    tetrabutyl urea 5.33
    diisobutyl methanol 1.44
    2-phenylethanol 3.03
    styrene 0.75
    dioctyl adipate 2.93
    dimethyl sulfate 12.63
    ethyl butyrate 1.83
    methyl lactate 8.18
    butyl lactate 5.02
    diethyl carbonate 1.61
    propanediol butyl ether 11.09
    triethyl orthoformate 2.02
    p-tert-butyltoluene 0.96
    methyl 4-tert-butylbenzoate 6.7
    morpholine 8.5
    tert-butylamine 3.16
    n-dodecanol 1.32
    dimethoxymethane 10.81
    ethylene carbonate 5.39
    cyrene 14.7
    2-ethoxyethyl acetate 3.99
    2-ethylhexyl acetate 1.55
    1,2,4-trichlorobenzene 1.63
    4-methylpyridine 4.81
    dibutyl ether 1.34
    2,6-dimethyl-4-heptanol 1.44
    DEF 10.41
    dimethyl isosorbide 12.5
    tetrachloroethylene 2.28
    eugenol 8.3
    triacetin 5.27
    span 80 9.29
    1,4-butanediol 9.88
    1,1-dichloroethane 0.87
    2-methyl-1-pentanol 3.05
    methyl formate 27.64
    2-methyl-1-butanol 4.08
    n-decane 0.26
    butyronitrile 2.84
    3,7-dimethyl-1-octanol 2.05
    1-chlorooctane 0.62
    1-chlorotetradecane 0.37
    n-nonane 0.26
    undecane 0.22
    tert-butylcyclohexane 0.24
    cyclooctane 0.25
    cyclopentanol 4.07
    tetrahydropyran 2.19
    tert-amyl methyl ether 2.43
    2,5,8-trioxanonane 20.54
    1-hexene 0.7
    2-isopropoxyethanol 6.28
    2,2,2-trifluoroethanol 17.43
    methyl butyrate 2.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction