Sodium cacodylate

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  • Identifiers

    CAS number
    124-65-2

    Molecular formula
    C2H6AsNaO2

    SMILES
    C[As](=O)(C)[O-].[Na+]

  • Odor profile

    Fragrance
    Odorless 39.45%
    Sweet 38.95%
    Pungent 24.8%
    Sharp 23.83%
    Creamy 23.8%
    Buttery 23.44%
    Ethereal 22.22%
    Nutty 22.0%
    Fruity 21.25%
    Musty 21.1%

     

    Flavor
    Pungent 29.07%
    Odorless 25.93%
    Sulfurous 22.95%
    Sharp 22.55%
    Mousy 22.1%
    Sour 21.48%
    Ethereal 21.06%
    Soy 20.52%
    Vinegar 20.21%
    Acetoin 19.87%

     

  • Properties

    pKa est.
    6.05 (neutral)

    Molecular weight
    159.98 g/mol

    Flash point

    • 101.07 ˚C est.

  • Synonyms

    • SODIUM CACODYLATE
    • Sodium dimethylarsinate
    • 124-65-2
    • Arsicodile
    • Cacodylic acid sodium salt
    • Dimethylarsinic acid sodium salt
    • Alkarsodyl
    • Sodium dimethylarsonate
    • Sodium dimethyl arsinate
    • Arsecodile
    • Arsycodile
    • Bolate
    • Cacodylate de sodium
    • Bolls-eye
    • Sodium salt of cacodylic acid
    • ((Dimethylarsino)oxy)sodium As-oxide
    • ((Dimethylarsino)oxy)sodium-As-oxide
    • Rad-E-Cate 25
    • Hydroxydimethylarsine oxide, sodium salt
    • CHEBI:62956
    • UN1688
    • Arsinic acid, As,As-dimethyl-, sodium salt (1:1)
    • OC4237N148
    • Arsysodila
    • Chemaid
    • Bophy
    • Dutch-treat
    • Rad-E-Cate
    • Sodium dimethylarsinate (0.1M buffer soln., pH 7.0)
    • Caswell No. 133A
    • Rad-E-Cate 16
    • Kakodylan dodny
    • Kakodylan dodny [Czech]
    • Dimethylarsinat sodny [Czech]
    • Dimethylarsinat sodny
    • Cacodylate de sodium [French]
    • NSC-1910
    • CCRIS 7929
    • HSDB 731
    • Sodium cacodylate [NF]
    • NSC 1910
    • EINECS 204-708-2
    • Arsinic acid, dimethyl-, sodium salt
    • EPA Pesticide Chemical Code 012502
    • Broadsides
    • Sodium, ((dimethylarsino)oxy)-, As-oxide
    • Arsine oxide, hydroxydimethyl-, sodium salt
    • UNII-OC4237N148
    • Cacodylic acid sodium salt hydrate
    • sodium;dimethylarsinate
    • sodium dimethyl arsonide
    • Arsine oxide, dimethylhydroxy-, sodium salt
    • SCHEMBL43010
    • SODIUM CACODYLATE [MI]
    • CHEMBL2079844
    • DTXSID3034408
    • SODIUM CACODYLATE [HSDB]
    • SODIUM CACODYLATE [MART.]
    • SODIUM CACODYLATE [WHO-DD]
    • AKOS016010300
    • Sodium cacodylate [UN1688] [Poison]
    • NS00079363
    • Q26840782

  • Applications

    Sodium cacodylate is primarily used as a buffering agent in biochemical and histological sample preparation, particularly for electron microscopy. It is commonly employed in fixation protocols (often with osmium tetroxide or glutaraldehyde) to preserve cellular ultrastructure. In histology and microscopy workflows it helps maintain pH during processing and staining. It also appears in analytical laboratory reagents as a buffering option for various assays, with use restricted to controlled environments due to its arsenic content and applicable safety regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 248.49
    methanol 502.09
    isopropanol 156.72
    water 314.97
    ethyl acetate 66.87
    n-propanol 147.61
    acetone 262.93
    n-butanol 104.99
    acetonitrile 175.35
    DMF 433.53
    toluene 37.03
    isobutanol 94.16
    1,4-dioxane 180.16
    methyl acetate 99.33
    THF 257.81
    2-butanone 125.43
    n-pentanol 67.7
    sec-butanol 104.65
    n-hexane 27.88
    ethylene glycol 221.47
    NMP 285.63
    cyclohexane 39.53
    DMSO 329.55
    n-butyl acetate 46.9
    n-octanol 61.49
    chloroform 123.97
    n-propyl acetate 52.4
    acetic acid 209.04
    dichloromethane 114.94
    cyclohexanone 130.96
    propylene glycol 159.66
    isopropyl acetate 42.64
    DMAc 287.04
    2-ethoxyethanol 161.89
    isopentanol 65.72
    n-heptane 28.04
    ethyl formate 81.5
    1,2-dichloroethane 87.44
    n-hexanol 77.77
    2-methoxyethanol 323.43
    isobutyl acetate 35.11
    tetrachloromethane 38.8
    n-pentyl acetate 42.64
    transcutol 225.29
    n-heptanol 54.26
    ethylbenzene 22.38
    MIBK 49.92
    2-propoxyethanol 165.48
    tert-butanol 124.21
    MTBE 59.54
    2-butoxyethanol 97.69
    propionic acid 129.82
    o-xylene 36.53
    formic acid 255.37
    diethyl ether 103.86
    m-xylene 32.52
    p-xylene 30.16
    chlorobenzene 37.65
    dimethyl carbonate 61.3
    n-octane 12.56
    formamide 295.39
    cyclopentanone 179.48
    2-pentanone 87.68
    anisole 54.27
    cyclopentyl methyl ether 105.98
    gamma-butyrolactone 160.66
    1-methoxy-2-propanol 195.83
    pyridine 106.61
    3-pentanone 85.82
    furfural 156.58
    n-dodecane 9.8
    diethylene glycol 199.7
    diisopropyl ether 30.21
    tert-amyl alcohol 81.83
    acetylacetone 91.51
    n-hexadecane 10.05
    acetophenone 60.44
    methyl propionate 84.0
    isopentyl acetate 37.88
    trichloroethylene 99.5
    n-nonanol 54.18
    cyclohexanol 94.67
    benzyl alcohol 60.87
    2-ethylhexanol 43.54
    isooctanol 37.66
    dipropyl ether 64.57
    1,2-dichlorobenzene 36.64
    ethyl lactate 54.52
    propylene carbonate 75.2
    n-methylformamide 235.62
    2-pentanol 70.18
    n-pentane 37.77
    1-propoxy-2-propanol 109.9
    1-methoxy-2-propyl acetate 62.33
    2-(2-methoxypropoxy) propanol 87.47
    mesitylene 24.07
    ε-caprolactone 93.2
    p-cymene 26.12
    epichlorohydrin 128.14
    1,1,1-trichloroethane 60.87
    2-aminoethanol 217.77
    morpholine-4-carbaldehyde 260.77
    sulfolane 192.08
    2,2,4-trimethylpentane 11.58
    2-methyltetrahydrofuran 123.85
    n-hexyl acetate 58.06
    isooctane 8.78
    2-(2-butoxyethoxy)ethanol 115.07
    sec-butyl acetate 32.25
    tert-butyl acetate 45.57
    decalin 13.89
    glycerin 232.48
    diglyme 188.56
    acrylic acid 137.2
    isopropyl myristate 31.59
    n-butyric acid 92.33
    acetyl acetate 49.5
    di(2-ethylhexyl) phthalate 36.53
    ethyl propionate 52.74
    nitromethane 241.69
    1,2-diethoxyethane 71.66
    benzonitrile 53.89
    trioctyl phosphate 31.14
    1-bromopropane 56.82
    gamma-valerolactone 193.77
    n-decanol 42.36
    triethyl phosphate 33.82
    4-methyl-2-pentanol 38.26
    propionitrile 93.52
    vinylene carbonate 73.63
    1,1,2-trichlorotrifluoroethane 146.84
    DMS 54.4
    cumene 21.02
    2-octanol 38.37
    2-hexanone 61.59
    octyl acetate 42.56
    limonene 36.41
    1,2-dimethoxyethane 213.65
    ethyl orthosilicate 32.68
    tributyl phosphate 32.06
    diacetone alcohol 78.58
    N,N-dimethylaniline 61.6
    acrylonitrile 119.59
    aniline 71.32
    1,3-propanediol 171.69
    bromobenzene 28.51
    dibromomethane 89.9
    1,1,2,2-tetrachloroethane 97.27
    2-methyl-cyclohexyl acetate 43.94
    tetrabutyl urea 53.28
    diisobutyl methanol 29.71
    2-phenylethanol 60.84
    styrene 26.03
    dioctyl adipate 45.91
    dimethyl sulfate 91.56
    ethyl butyrate 44.59
    methyl lactate 93.0
    butyl lactate 51.34
    diethyl carbonate 33.94
    propanediol butyl ether 104.36
    triethyl orthoformate 40.22
    p-tert-butyltoluene 26.91
    methyl 4-tert-butylbenzoate 65.6
    morpholine 200.41
    tert-butylamine 91.52
    n-dodecanol 35.28
    dimethoxymethane 224.43
    ethylene carbonate 63.77
    cyrene 94.32
    2-ethoxyethyl acetate 55.68
    2-ethylhexyl acetate 33.53
    1,2,4-trichlorobenzene 45.39
    4-methylpyridine 85.24
    dibutyl ether 42.58
    2,6-dimethyl-4-heptanol 29.71
    DEF 119.32
    dimethyl isosorbide 118.86
    tetrachloroethylene 82.61
    eugenol 80.75
    triacetin 66.35
    span 80 88.35
    1,4-butanediol 88.99
    1,1-dichloroethane 74.02
    2-methyl-1-pentanol 44.14
    methyl formate 172.46
    2-methyl-1-butanol 68.97
    n-decane 14.59
    butyronitrile 74.11
    3,7-dimethyl-1-octanol 44.9
    1-chlorooctane 31.58
    1-chlorotetradecane 17.27
    n-nonane 14.62
    undecane 11.44
    tert-butylcyclohexane 12.22
    cyclooctane 16.27
    cyclopentanol 127.1
    tetrahydropyran 125.0
    tert-amyl methyl ether 52.52
    2,5,8-trioxanonane 149.89
    1-hexene 42.77
    2-isopropoxyethanol 94.17
    2,2,2-trifluoroethanol 130.99
    methyl butyrate 61.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction