Sciadopitysin

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  • Identifiers

    CAS number
    521-34-6

    Molecular formula
    C33H24O10

    SMILES
    COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)OC)O)OC

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 49.1%
    Sweet 36.0%
    Odorless 34.41%
    Fruity 34.13%
    Vanilla 29.39%
    Burnt 27.58%
    Spicy 26.83%
    Powdery 25.96%
    Balsamic 25.63%
    Animal 24.25%

     

    Flavor
    Bitter 96.04%
    Odorless 20.44%
    Bland 19.99%
    Parsley 19.51%
    Cedarleaf 19.35%
    Sweet-like 19.21%
    Lovage 18.89%
    Very strong 18.45%
    Indole 18.4%
    Nitrile 18.29%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.0

    pKa est.
    8.59 (weak base)

    Molecular weight
    580.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2281°C

    Flash point

    • 289.2 ˚C est.

  • Synonyms

    • Sciadopitysin
    • 521-34-6
    • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one
    • Amentoflavone-7,4',4'''-trimethyl ether
    • WL44VY201L
    • DTXSID30200096
    • NSC-45108
    • CHEBI:9050
    • 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4H-chromen-4-one
    • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4H-chromen-4-one
    • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)chromen-4-one
    • RefChem:181880
    • DTXCID30122587
    • 208-311-5
    • NSC45108
    • MFCD00017448
    • 5,7-Dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4-benzopyrone
    • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-2-(4-methoxyphenyl)chromen-4-one
    • C33H24O10
    • 7,4',4'''-Trimethylamentoflavone
    • EINECS 208-311-5
    • NSC 45108
    • Sciadopitysin (Standard)
    • UNII-WL44VY201L
    • jm5b01461, Compound 88
    • orb1301256
    • SCHEMBL1158050
    • SCHEMBL30996894
    • HY-N2119R
    • WLZ4718
    • BDBM429270
    • HY-N2119
    • LMPK12040006
    • AKOS030231209
    • Amentoflavone-7,4'4'''trimethylether
    • EBC-616757
    • FS65450
    • NCGC00163619-01
    • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-
    • AC-34337
    • AS-79283
    • DB-052078
    • CS-0018639
    • NS00032432
    • AA-504/21125014
    • Q27108253
    • 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1- benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4- benzopyrone
    • 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
    • 521-34-6

  • Applications

    Sciadopitysin, a biflavonoid, is primarily studied as a natural product with potential applications across several industries. It is commonly evaluated as an antioxidant and stabilizer in cosmetics and personal care formulations; investigated as a bioactive intermediate or lead compound in pharmaceutical research; explored as a functional additive in polymer and coating systems to improve oxidative stability; and examined in agricultural or plant-protection research for its bioactivity in plant extracts.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.13
    methanol 0.26
    isopropanol 0.13
    water 0.0
    ethyl acetate 0.21
    n-propanol 0.28
    acetone 0.41
    n-butanol 0.16
    acetonitrile 0.09
    DMF 7.79
    toluene 0.03
    isobutanol 0.15
    1,4-dioxane 1.29
    methyl acetate 0.51
    THF 3.09
    2-butanone 0.8
    n-pentanol 0.09
    sec-butanol 0.19
    n-hexane 0.0
    ethylene glycol 0.33
    NMP 11.5
    cyclohexane 0.0
    DMSO 11.96
    n-butyl acetate 0.13
    n-octanol 0.03
    chloroform 0.53
    n-propyl acetate 0.16
    acetic acid 1.23
    dichloromethane 0.53
    cyclohexanone 1.02
    propylene glycol 0.55
    isopropyl acetate 0.12
    DMAc 11.35
    2-ethoxyethanol 1.05
    isopentanol 0.09
    n-heptane 0.0
    ethyl formate 0.27
    1,2-dichloroethane 0.31
    n-hexanol 0.03
    2-methoxyethanol 2.95
    isobutyl acetate 0.07
    tetrachloromethane 0.03
    n-pentyl acetate 0.11
    transcutol 1.79
    n-heptanol 0.04
    ethylbenzene 0.01
    MIBK 0.1
    2-propoxyethanol 0.92
    tert-butanol 0.12
    MTBE 0.09
    2-butoxyethanol 0.5
    propionic acid 0.85
    o-xylene 0.02
    formic acid 0.93
    diethyl ether 0.09
    m-xylene 0.01
    p-xylene 0.02
    chlorobenzene 0.05
    dimethyl carbonate 0.65
    n-octane 0.0
    formamide 1.31
    cyclopentanone 2.69
    2-pentanone 0.28
    anisole 0.09
    cyclopentyl methyl ether 0.25
    gamma-butyrolactone 3.92
    1-methoxy-2-propanol 1.71
    pyridine 0.87
    3-pentanone 0.27
    furfural 3.06
    n-dodecane 0.0
    diethylene glycol 1.04
    diisopropyl ether 0.01
    tert-amyl alcohol 0.15
    acetylacetone 0.55
    n-hexadecane 0.0
    acetophenone 0.2
    methyl propionate 0.54
    isopentyl acetate 0.11
    trichloroethylene 1.24
    n-nonanol 0.04
    cyclohexanol 0.13
    benzyl alcohol 0.15
    2-ethylhexanol 0.03
    isooctanol 0.03
    dipropyl ether 0.09
    1,2-dichlorobenzene 0.06
    ethyl lactate 0.33
    propylene carbonate 0.74
    n-methylformamide 2.01
    2-pentanol 0.07
    n-pentane 0.0
    1-propoxy-2-propanol 0.62
    1-methoxy-2-propyl acetate 0.5
    2-(2-methoxypropoxy) propanol 0.8
    mesitylene 0.01
    ε-caprolactone 1.1
    p-cymene 0.01
    epichlorohydrin 3.94
    1,1,1-trichloroethane 0.1
    2-aminoethanol 0.52
    morpholine-4-carbaldehyde 8.29
    sulfolane 11.44
    2,2,4-trimethylpentane 0.0
    2-methyltetrahydrofuran 0.61
    n-hexyl acetate 0.11
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 0.76
    sec-butyl acetate 0.08
    tert-butyl acetate 0.13
    decalin 0.0
    glycerin 2.17
    diglyme 2.06
    acrylic acid 1.38
    isopropyl myristate 0.04
    n-butyric acid 0.5
    acetyl acetate 0.18
    di(2-ethylhexyl) phthalate 0.1
    ethyl propionate 0.18
    nitromethane 3.54
    1,2-diethoxyethane 0.25
    benzonitrile 0.09
    trioctyl phosphate 0.06
    1-bromopropane 0.08
    gamma-valerolactone 8.82
    n-decanol 0.03
    triethyl phosphate 0.16
    4-methyl-2-pentanol 0.03
    propionitrile 0.16
    vinylene carbonate 0.78
    1,1,2-trichlorotrifluoroethane 8.01
    DMS 0.27
    cumene 0.01
    2-octanol 0.02
    2-hexanone 0.19
    octyl acetate 0.07
    limonene 0.02
    1,2-dimethoxyethane 1.82
    ethyl orthosilicate 0.12
    tributyl phosphate 0.08
    diacetone alcohol 0.49
    N,N-dimethylaniline 0.08
    acrylonitrile 0.4
    aniline 0.15
    1,3-propanediol 0.71
    bromobenzene 0.04
    dibromomethane 0.16
    1,1,2,2-tetrachloroethane 1.11
    2-methyl-cyclohexyl acetate 0.11
    tetrabutyl urea 0.15
    diisobutyl methanol 0.02
    2-phenylethanol 0.08
    styrene 0.01
    dioctyl adipate 0.14
    dimethyl sulfate 2.78
    ethyl butyrate 0.15
    methyl lactate 1.22
    butyl lactate 0.26
    diethyl carbonate 0.12
    propanediol butyl ether 0.46
    triethyl orthoformate 0.21
    p-tert-butyltoluene 0.01
    methyl 4-tert-butylbenzoate 0.3
    morpholine 2.27
    tert-butylamine 0.03
    n-dodecanol 0.02
    dimethoxymethane 1.75
    ethylene carbonate 0.47
    cyrene 1.42
    2-ethoxyethyl acetate 0.38
    2-ethylhexyl acetate 0.08
    1,2,4-trichlorobenzene 0.15
    4-methylpyridine 0.34
    dibutyl ether 0.06
    2,6-dimethyl-4-heptanol 0.02
    DEF 0.84
    dimethyl isosorbide 1.5
    tetrachloroethylene 0.44
    eugenol 0.35
    triacetin 0.41
    span 80 0.49
    1,4-butanediol 0.19
    1,1-dichloroethane 0.12
    2-methyl-1-pentanol 0.06
    methyl formate 1.37
    2-methyl-1-butanol 0.13
    n-decane 0.0
    butyronitrile 0.09
    3,7-dimethyl-1-octanol 0.03
    1-chlorooctane 0.01
    1-chlorotetradecane 0.0
    n-nonane 0.0
    undecane 0.0
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 0.34
    tetrahydropyran 0.38
    tert-amyl methyl ether 0.09
    2,5,8-trioxanonane 1.37
    1-hexene 0.01
    2-isopropoxyethanol 0.44
    2,2,2-trifluoroethanol 0.66
    methyl butyrate 0.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction