Rosmarinyl glucoside

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  • Identifiers

    CAS number
    910028-78-3

    Molecular formula
    C24H26O13

    SMILES
    C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

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  • Odor profile

    Fragrance
    Odorless 79.3%
    Savory 25.85%
    Vanilla 25.1%
    Milky 23.62%
    Balsamic 19.14%
    Burnt 17.57%
    Bitter 17.15%
    Phenolic 16.87%
    Dairy 16.5%
    Spicy 16.46%

     

    Flavor
    Bitter 70.73%
    Odorless 49.6%
    Bland 37.85%
    Very mild 28.18%
    Sweet-like 26.3%
    Mild 23.17%
    Parsley 19.23%
    Cedarleaf 19.09%
    Nitrile 18.94%
    Ethyl benzoate 18.87%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    8.12 (weak base)

    Molecular weight
    522.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2497°C

    Flash point

    • 311.75 ˚C est.

  • Synonyms

    • Rosmarinyl glucoside
    • 910028-78-3
    • Inoveol rosmarinic acid-glucoside
    • UNII-3LBK307OWD
    • 3LBK307OWD
    • Rosmarinic acid 4-O-beta-d-glucoside
    • 4-O-beta-d-Glucopyranosylrosmarinic acid
    • DTXSID20238363
    • ROSMARINIC ACID 4-O-.BETA.-D-GLUCOSIDE
    • 4-O-.BETA.-D-GLUCOPYRANOSYLROSMARINIC ACID
    • Benzenepropanoic acid, alpha-(((2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl)oxy)-4-(beta-d-glucopyranosyloxy)-3-hydroxy-, (alphaR)-
    • Benzenepropanoic acid, alpha-(((2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-4-(beta-d-glucopyranosyloxy)-3-hydroxy-, (alphaR)-
    • BENZENEPROPANOIC ACID, .ALPHA.-(((2E)-3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPEN-1-YL)OXY)-4-(.BETA.-D-GLUCOPYRANOSYLOXY)-3-HYDROXY-, (.ALPHA.R)-
    • BENZENEPROPANOIC ACID, .ALPHA.-(((2E)-3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY)-4-(.BETA.-D-GLUCOPYRANOSYLOXY)-3-HYDROXY-, (.ALPHA.R)-
    • RefChem:179930
    • DTXCID40160854
    • ROSMARINYL GLUCOSIDE [INCI]
    • (2R)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-3-[3-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propanoic acid
    • orb1680229
    • SCHEMBL26550567
    • AKOS032946711
    • FS-8382
    • Q27257535
    • (2R)-2-{[(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy}-3-[4-(beta-D-glucopyranosyloxy)-3-hydroxyphenyl]propanoic acid
    • 910028-78-3

  • Applications

    Rosmarinyl glucoside (CAS 910028-78-3) is used primarily as an aroma ingredient and a precursor in cosmetic and food-related formulations, delivering rosemary notes in perfumery and suitable for fragrance use in skincare and haircare products, where it may also function as a fragrance fixative. It is also considered as a precursor or aroma source for flavor formulations, enabling release or adjustment of rosemary-like notes in foods and beverages where appropriate. In household cleaning products, it can be added as a fragrance component to improve product scent. In industrial manufacturing, Rosmarinyl glucoside may serve as an intermediate for synthesizing rosmarinic acid–related derivatives or other natural aroma compounds, broadening the range of rosemary-derived fragrances. These uses depend on formulation limits and compliance with local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 316.65
    methanol 336.41
    isopropanol 182.5
    water 15.73
    ethyl acetate 66.62
    n-propanol 173.75
    acetone 679.81
    n-butanol 79.1
    acetonitrile 73.63
    DMF 556.47
    toluene 3.93
    isobutanol 41.38
    1,4-dioxane 283.99
    methyl acetate 88.16
    THF 816.46
    2-butanone 183.75
    n-pentanol 30.39
    sec-butanol 76.99
    n-hexane 0.29
    ethylene glycol 324.52
    NMP 225.77
    cyclohexane 1.23
    DMSO 3646.34
    n-butyl acetate 3.44
    n-octanol 10.45
    chloroform 2.86
    n-propyl acetate 9.29
    acetic acid 646.41
    dichloromethane 5.75
    cyclohexanone 90.54
    propylene glycol 280.29
    isopropyl acetate 25.07
    DMAc 496.23
    2-ethoxyethanol 339.42
    isopentanol 23.71
    n-heptane 0.6
    ethyl formate 54.73
    1,2-dichloroethane 11.66
    n-hexanol 8.83
    2-methoxyethanol 1003.2
    isobutyl acetate 1.51
    tetrachloromethane 0.64
    n-pentyl acetate 6.91
    transcutol 140.59
    n-heptanol 9.24
    ethylbenzene 0.85
    MIBK 17.91
    2-propoxyethanol 85.1
    tert-butanol 92.04
    MTBE 21.72
    2-butoxyethanol 42.93
    propionic acid 109.34
    o-xylene 2.05
    formic acid 542.56
    diethyl ether 53.77
    m-xylene 1.4
    p-xylene 0.8
    chlorobenzene 1.11
    dimethyl carbonate 58.32
    n-octane 0.47
    formamide 829.52
    cyclopentanone 276.37
    2-pentanone 108.22
    anisole 6.73
    cyclopentyl methyl ether 52.36
    gamma-butyrolactone 217.05
    1-methoxy-2-propanol 434.22
    pyridine 66.14
    3-pentanone 47.61
    furfural 80.96
    n-dodecane 0.35
    diethylene glycol 137.12
    diisopropyl ether 3.76
    tert-amyl alcohol 44.78
    acetylacetone 173.25
    n-hexadecane 0.39
    acetophenone 7.43
    methyl propionate 81.77
    isopentyl acetate 1.78
    trichloroethylene 10.38
    n-nonanol 10.26
    cyclohexanol 37.65
    benzyl alcohol 13.58
    2-ethylhexanol 1.87
    isooctanol 4.14
    dipropyl ether 10.38
    1,2-dichlorobenzene 0.53
    ethyl lactate 13.14
    propylene carbonate 22.32
    n-methylformamide 348.02
    2-pentanol 32.24
    n-pentane 0.77
    1-propoxy-2-propanol 36.38
    1-methoxy-2-propyl acetate 12.79
    2-(2-methoxypropoxy) propanol 24.13
    mesitylene 0.69
    ε-caprolactone 53.16
    p-cymene 0.4
    epichlorohydrin 173.64
    1,1,1-trichloroethane 2.39
    2-aminoethanol 343.74
    morpholine-4-carbaldehyde 257.02
    sulfolane 356.02
    2,2,4-trimethylpentane 0.15
    2-methyltetrahydrofuran 131.33
    n-hexyl acetate 8.37
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 59.08
    sec-butyl acetate 3.77
    tert-butyl acetate 17.25
    decalin 0.14
    glycerin 457.5
    diglyme 102.56
    acrylic acid 110.45
    isopropyl myristate 3.02
    n-butyric acid 91.14
    acetyl acetate 26.23
    di(2-ethylhexyl) phthalate 2.2
    ethyl propionate 10.23
    nitromethane 859.86
    1,2-diethoxyethane 25.72
    benzonitrile 3.38
    trioctyl phosphate 2.8
    1-bromopropane 4.33
    gamma-valerolactone 392.0
    n-decanol 7.58
    triethyl phosphate 1.46
    4-methyl-2-pentanol 5.36
    propionitrile 21.35
    vinylene carbonate 16.07
    1,1,2-trichlorotrifluoroethane 95.47
    DMS 6.62
    cumene 0.39
    2-octanol 5.44
    2-hexanone 15.73
    octyl acetate 6.48
    limonene 0.88
    1,2-dimethoxyethane 186.05
    ethyl orthosilicate 1.56
    tributyl phosphate 1.93
    diacetone alcohol 78.05
    N,N-dimethylaniline 3.84
    acrylonitrile 32.56
    aniline 18.25
    1,3-propanediol 426.52
    bromobenzene 0.59
    dibromomethane 2.82
    1,1,2,2-tetrachloroethane 10.34
    2-methyl-cyclohexyl acetate 1.63
    tetrabutyl urea 6.12
    diisobutyl methanol 1.16
    2-phenylethanol 5.09
    styrene 1.09
    dioctyl adipate 5.13
    dimethyl sulfate 79.08
    ethyl butyrate 3.85
    methyl lactate 95.06
    butyl lactate 8.56
    diethyl carbonate 1.63
    propanediol butyl ether 45.47
    triethyl orthoformate 3.37
    p-tert-butyltoluene 0.44
    methyl 4-tert-butylbenzoate 7.83
    morpholine 387.07
    tert-butylamine 14.73
    n-dodecanol 5.29
    dimethoxymethane 424.91
    ethylene carbonate 17.06
    cyrene 36.04
    2-ethoxyethyl acetate 17.56
    2-ethylhexyl acetate 1.04
    1,2,4-trichlorobenzene 1.17
    4-methylpyridine 24.38
    dibutyl ether 6.99
    2,6-dimethyl-4-heptanol 1.16
    DEF 88.67
    dimethyl isosorbide 18.39
    tetrachloroethylene 5.68
    eugenol 7.58
    triacetin 10.45
    span 80 22.26
    1,4-butanediol 110.65
    1,1-dichloroethane 5.91
    2-methyl-1-pentanol 8.75
    methyl formate 264.71
    2-methyl-1-butanol 24.03
    n-decane 0.68
    butyronitrile 17.43
    3,7-dimethyl-1-octanol 3.21
    1-chlorooctane 1.95
    1-chlorotetradecane 0.76
    n-nonane 0.63
    undecane 0.47
    tert-butylcyclohexane 0.07
    cyclooctane 0.44
    cyclopentanol 115.69
    tetrahydropyran 128.09
    tert-amyl methyl ether 15.45
    2,5,8-trioxanonane 69.53
    1-hexene 1.27
    2-isopropoxyethanol 98.54
    2,2,2-trifluoroethanol 151.16
    methyl butyrate 13.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction