Rebaudioside I

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1220616-34-1

    Molecular formula
    C50H80O28

    SMILES
    C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)(C)C(=O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 70.71%
    Sweet 32.33%
    Cooling 22.92%
    Woody 22.22%
    Spicy 18.05%
    Clean 17.29%
    Milky 16.35%
    Mint 16.21%
    Warm 16.21%
    Alcoholic 16.19%

     

    Flavor
    Bitter 55.94%
    Sweet 45.53%
    Odorless 39.76%
    Fatty 35.03%
    Sweet-like 30.92%
    Bland 25.18%
    Cauliflower 21.47%
    Alkaline 21.0%
    Very slight 20.88%
    Cedarleaf 20.65%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -4.4

    pKa est.
    2.59 (strong acid)

    Molecular weight
    1129.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    4410°C

    Flash point

    • 200.9 ˚C est.

  • Synonyms

    • REBAUDIOSIDE I
    • 1220616-34-1
    • Fema No. 4937
    • 1U83C5T5N8
    • UNII-1U83C5T5N8
    • KAUR-16-EN-18-oic acid, 13-((o-beta-D-glucopyranosyl-(1->2)-O-(beta-D-glucopyranosyl-(1->3))-beta-D-glucopyranosyl)oxy)-, 3-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester, (4alpha)-
    • RefChem:45986
    • orb1707848
    • SCHEMBL29363473
    • DTXSID901347268
    • HY-N6889
    • AKOS040740896
    • OR46451
    • DA-67135
    • MS-31993
    • CS-0100497
    • F93956
    • Q63392189
    • KAUR-16-EN-18-OIC ACID, 13-((O-.BETA.-D-GLUCOPYRANOSYL-(1->2)-O-(.BETA.-D-GLUCOPYRANOSYL-(1->3))-.BETA.-D-GLUCOPYRANOSYL)OXY)-, 3-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-
    • 1220616-34-1

  • Applications

    Rebaudioside I, a high-intensity steviol glycoside (CAS 1220616-34-1), is used primarily as a sugar substitute in food and beverage formulations to reduce sugar and calories. Application areas include food processing and beverages; confectionery and dairy products; pharmaceutical taste masking in oral dosage forms; and nutrition/dietary supplement products.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.27
    methanol 31.8
    isopropanol 1.19
    water 0.68
    ethyl acetate 4.19
    n-propanol 2.12
    acetone 5.52
    n-butanol 1.07
    acetonitrile 2.69
    DMF 74.14
    toluene 0.82
    isobutanol 0.74
    1,4-dioxane 10.73
    methyl acetate 5.01
    THF 20.12
    2-butanone 3.77
    n-pentanol 0.66
    sec-butanol 0.83
    n-hexane 0.03
    ethylene glycol 10.98
    NMP 88.42
    cyclohexane 0.07
    DMSO 77.05
    n-butyl acetate 1.27
    n-octanol 0.75
    chloroform 4.46
    n-propyl acetate 1.49
    acetic acid 52.18
    dichloromethane 5.18
    cyclohexanone 5.21
    propylene glycol 8.12
    isopropyl acetate 2.08
    DMAc 61.96
    2-ethoxyethanol 11.01
    isopentanol 0.53
    n-heptane 0.06
    ethyl formate 4.64
    1,2-dichloroethane 2.47
    n-hexanol 0.56
    2-methoxyethanol 34.09
    isobutyl acetate 0.6
    tetrachloromethane 0.59
    n-pentyl acetate 2.02
    transcutol 16.63
    n-heptanol 0.95
    ethylbenzene 0.25
    MIBK 1.14
    2-propoxyethanol 9.77
    tert-butanol 0.72
    MTBE 0.63
    2-butoxyethanol 7.18
    propionic acid 6.81
    o-xylene 0.57
    formic acid 94.15
    diethyl ether 1.3
    m-xylene 0.52
    p-xylene 0.27
    chlorobenzene 0.82
    dimethyl carbonate 13.64
    n-octane 0.04
    formamide 65.42
    cyclopentanone 14.24
    2-pentanone 2.71
    anisole 1.34
    cyclopentyl methyl ether 3.53
    gamma-butyrolactone 28.81
    1-methoxy-2-propanol 16.53
    pyridine 7.41
    3-pentanone 2.52
    furfural 32.8
    n-dodecane 0.02
    diethylene glycol 16.36
    diisopropyl ether 0.23
    tert-amyl alcohol 0.62
    acetylacetone 10.01
    n-hexadecane 0.03
    acetophenone 2.4
    methyl propionate 6.96
    isopentyl acetate 0.84
    trichloroethylene 8.11
    n-nonanol 0.8
    cyclohexanol 0.9
    benzyl alcohol 2.04
    2-ethylhexanol 0.29
    isooctanol 0.54
    dipropyl ether 0.9
    1,2-dichlorobenzene 0.97
    ethyl lactate 3.66
    propylene carbonate 10.88
    n-methylformamide 35.59
    2-pentanol 0.5
    n-pentane 0.04
    1-propoxy-2-propanol 5.12
    1-methoxy-2-propyl acetate 5.87
    2-(2-methoxypropoxy) propanol 4.71
    mesitylene 0.27
    ε-caprolactone 7.41
    p-cymene 0.23
    epichlorohydrin 17.92
    1,1,1-trichloroethane 1.23
    2-aminoethanol 9.99
    morpholine-4-carbaldehyde 65.84
    sulfolane 64.48
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 3.83
    n-hexyl acetate 1.88
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 6.93
    sec-butyl acetate 0.78
    tert-butyl acetate 1.81
    decalin 0.03
    glycerin 30.78
    diglyme 16.48
    acrylic acid 17.22
    isopropyl myristate 0.43
    n-butyric acid 5.85
    acetyl acetate 5.75
    di(2-ethylhexyl) phthalate 0.89
    ethyl propionate 1.77
    nitromethane 71.63
    1,2-diethoxyethane 2.46
    benzonitrile 1.48
    trioctyl phosphate 0.68
    1-bromopropane 0.54
    gamma-valerolactone 44.45
    n-decanol 0.47
    triethyl phosphate 1.13
    4-methyl-2-pentanol 0.27
    propionitrile 1.41
    vinylene carbonate 13.27
    1,1,2-trichlorotrifluoroethane 42.26
    DMS 4.03
    cumene 0.15
    2-octanol 0.46
    2-hexanone 1.1
    octyl acetate 0.9
    limonene 0.33
    1,2-dimethoxyethane 10.84
    ethyl orthosilicate 0.92
    tributyl phosphate 0.6
    diacetone alcohol 5.0
    N,N-dimethylaniline 1.18
    acrylonitrile 4.25
    aniline 1.9
    1,3-propanediol 8.48
    bromobenzene 0.7
    dibromomethane 1.82
    1,1,2,2-tetrachloroethane 5.14
    2-methyl-cyclohexyl acetate 0.99
    tetrabutyl urea 1.15
    diisobutyl methanol 0.2
    2-phenylethanol 1.58
    styrene 0.32
    dioctyl adipate 1.13
    dimethyl sulfate 35.84
    ethyl butyrate 1.41
    methyl lactate 18.65
    butyl lactate 3.19
    diethyl carbonate 1.06
    propanediol butyl ether 7.29
    triethyl orthoformate 1.54
    p-tert-butyltoluene 0.24
    methyl 4-tert-butylbenzoate 4.3
    morpholine 13.64
    tert-butylamine 0.21
    n-dodecanol 0.27
    dimethoxymethane 29.95
    ethylene carbonate 7.24
    cyrene 11.84
    2-ethoxyethyl acetate 5.91
    2-ethylhexyl acetate 0.67
    1,2,4-trichlorobenzene 1.61
    4-methylpyridine 3.7
    dibutyl ether 0.43
    2,6-dimethyl-4-heptanol 0.2
    DEF 8.2
    dimethyl isosorbide 10.09
    tetrachloroethylene 4.07
    eugenol 4.26
    triacetin 6.04
    span 80 4.85
    1,4-butanediol 2.73
    1,1-dichloroethane 1.24
    2-methyl-1-pentanol 0.35
    methyl formate 30.49
    2-methyl-1-butanol 0.59
    n-decane 0.06
    butyronitrile 0.85
    3,7-dimethyl-1-octanol 0.39
    1-chlorooctane 0.24
    1-chlorotetradecane 0.07
    n-nonane 0.05
    undecane 0.03
    tert-butylcyclohexane 0.02
    cyclooctane 0.05
    cyclopentanol 2.05
    tetrahydropyran 2.69
    tert-amyl methyl ether 0.74
    2,5,8-trioxanonane 9.91
    1-hexene 0.1
    2-isopropoxyethanol 3.86
    2,2,2-trifluoroethanol 25.25
    methyl butyrate 2.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction