Quinoxyfen

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  • Identifiers

    CAS number
    124495-18-7

    Molecular formula
    C15H8Cl2FNO

    SMILES
    C1=CC(=CC=C1OC2=C3C(=CC(=CC3=NC=C2)Cl)Cl)F

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Fruity 49.98%
    Floral 40.74%
    Animal 36.91%
    Phenolic 34.63%
    Sweet 28.05%
    Grape 25.57%
    Burnt 25.09%
    Powdery 22.62%
    Musk 21.91%
    Neroli 21.86%

     

    Flavor
    Bitter 82.67%
    Odorless 25.55%
    Mild 22.7%
    Very strong 21.77%
    Indole 21.19%
    Nitrile 20.49%
    Orange flower 19.71%
    Sweet-like 19.71%
    Moth ball 19.6%
    Scallion 19.58%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    6.87 (neutral)

    Molecular weight
    308.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    411°C

    Melting point expt.

    • 105-106 °C
    • MP: 100-106 °C /Technical/

    Flash point

    • 187.17 ˚C est.
    • > 199 °F (>93 °C) (Closed cup) /Quintec Fungicide/

    Solubility expt.

    • In acetone 116, dichloromethane 589, ethyl acetate 179, methanol 21.5, n-octanol 37.9, toluene 272, hexane 9.64, xylene 200 (all in g/L, 20 °C)
    • In water, 0.128 (pH 5); 0.047 (pH 7); 0.036 (pH 9) (all in g/L, 20 °C)
    • In water, 116 ug/L at 20 °C (pH 6.45)

  • Synonyms

    • Quinoxyfen
    • 124495-18-7
    • 5,7-dichloro-4-(4-fluorophenoxy)quinoline
    • Quinoline, 5,7-dichloro-4-(4-fluorophenoxy)-
    • QUINTEC
    • DE 795
    • HSDB 7946
    • PPC78J1VCW
    • DTXSID2034881
    • DE-795
    • DTXCID0014881
    • 5,7-dichloro-4-quinolyl 4-fluorophenyl ether
    • CHEBI:82040
    • RefChem:872074
    • 602-997-3
    • Legend; DE 795
    • (5,7-Dichloro-4-quinolyl) (4-fluorophenyl) ether
    • MFCD03265638
    • Quinoxyfen 10 microg/mL in Cyclohexane
    • Quinoxyfen 10 microg/mL in Acetonitrile
    • Quinoxyfen [ISO]
    • Quinoxyfen [ISO:BSI:ANSI]
    • UNII-PPC78J1VCW
    • quinoxifen
    • QUINOXYFEN [MI]
    • SCHEMBL22257
    • orb1705494
    • orb3025135
    • CHEMBL1869863
    • EX-A7271
    • MSK21139
    • Tox21_300844
    • AKOS025243116
    • KS-5368
    • NCGC00163706-01
    • NCGC00163706-02
    • NCGC00163706-03
    • NCGC00163706-04
    • NCGC00254747-01
    • DB-062253
    • HY-120734
    • CAS-124495-18-7
    • CS-0078946
    • NS00010580
    • Q0093
    • Quinoxyfen, PESTANAL(R), analytical standard
    • A11970
    • C18892
    • Q961155
    • 124495-18-7

  • Applications

    Quinoxyfen (CAS 124495-18-7) is a fungicidal active ingredient used in agriculture to control powdery mildew on a range of crops, notably grapes, fruit trees, strawberries, cucumbers, and ornamentals. It is typically applied as a foliar spray in field or greenhouse settings and formulated in products as emulsifiable concentrates or wettable powders. It is commonly integrated into pest management programs, with use subject to local regulations, label directions, and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 31.45
    methanol 17.68
    isopropanol 19.07
    water 0.01
    ethyl acetate 84.9
    n-propanol 38.15
    acetone 41.55
    n-butanol 35.24
    acetonitrile 51.69
    DMF 20.68
    toluene 29.54
    isobutanol 23.98
    1,4-dioxane 121.14
    methyl acetate 79.2
    THF 201.29
    2-butanone 90.25
    n-pentanol 39.96
    sec-butanol 36.23
    n-hexane 1.36
    ethylene glycol 4.78
    NMP 19.75
    cyclohexane 1.64
    DMSO 48.07
    n-butyl acetate 76.04
    n-octanol 13.49
    chloroform 139.93
    n-propyl acetate 84.02
    acetic acid 34.38
    dichloromethane 170.04
    cyclohexanone 68.86
    propylene glycol 7.28
    isopropyl acetate 47.68
    DMAc 67.62
    2-ethoxyethanol 111.52
    isopentanol 32.83
    n-heptane 3.17
    ethyl formate 50.92
    1,2-dichloroethane 63.63
    n-hexanol 27.75
    2-methoxyethanol 94.76
    isobutyl acetate 44.65
    tetrachloromethane 4.15
    n-pentyl acetate 43.8
    transcutol 544.6
    n-heptanol 15.02
    ethylbenzene 23.6
    MIBK 33.44
    2-propoxyethanol 88.78
    tert-butanol 15.98
    MTBE 34.96
    2-butoxyethanol 54.18
    propionic acid 24.81
    o-xylene 16.26
    formic acid 10.72
    diethyl ether 49.86
    m-xylene 14.7
    p-xylene 23.54
    chlorobenzene 26.65
    dimethyl carbonate 23.06
    n-octane 1.27
    formamide 25.17
    cyclopentanone 57.95
    2-pentanone 55.4
    anisole 78.04
    cyclopentyl methyl ether 51.81
    gamma-butyrolactone 70.78
    1-methoxy-2-propanol 58.0
    pyridine 123.35
    3-pentanone 43.71
    furfural 105.14
    n-dodecane 1.65
    diethylene glycol 63.44
    diisopropyl ether 12.38
    tert-amyl alcohol 27.27
    acetylacetone 68.19
    n-hexadecane 1.92
    acetophenone 63.12
    methyl propionate 47.53
    isopentyl acetate 64.32
    trichloroethylene 160.26
    n-nonanol 15.53
    cyclohexanol 31.49
    benzyl alcohol 55.19
    2-ethylhexanol 26.25
    isooctanol 15.23
    dipropyl ether 50.94
    1,2-dichlorobenzene 25.15
    ethyl lactate 34.09
    propylene carbonate 46.68
    n-methylformamide 23.26
    2-pentanol 24.33
    n-pentane 1.1
    1-propoxy-2-propanol 63.05
    1-methoxy-2-propyl acetate 93.62
    2-(2-methoxypropoxy) propanol 87.22
    mesitylene 7.25
    ε-caprolactone 83.8
    p-cymene 16.32
    epichlorohydrin 166.95
    1,1,1-trichloroethane 32.61
    2-aminoethanol 15.39
    morpholine-4-carbaldehyde 82.09
    sulfolane 39.37
    2,2,4-trimethylpentane 1.73
    2-methyltetrahydrofuran 101.07
    n-hexyl acetate 44.13
    isooctane 0.83
    2-(2-butoxyethoxy)ethanol 124.09
    sec-butyl acetate 59.0
    tert-butyl acetate 39.66
    decalin 2.55
    glycerin 13.45
    diglyme 244.53
    acrylic acid 21.83
    isopropyl myristate 24.38
    n-butyric acid 42.43
    acetyl acetate 52.96
    di(2-ethylhexyl) phthalate 24.6
    ethyl propionate 68.68
    nitromethane 67.47
    1,2-diethoxyethane 196.78
    benzonitrile 59.22
    trioctyl phosphate 14.26
    1-bromopropane 46.48
    gamma-valerolactone 118.78
    n-decanol 12.63
    triethyl phosphate 32.65
    4-methyl-2-pentanol 15.11
    propionitrile 50.92
    vinylene carbonate 54.48
    1,1,2-trichlorotrifluoroethane 82.35
    DMS 54.97
    cumene 13.95
    2-octanol 11.67
    2-hexanone 70.36
    octyl acetate 27.5
    limonene 20.03
    1,2-dimethoxyethane 205.11
    ethyl orthosilicate 33.06
    tributyl phosphate 22.54
    diacetone alcohol 39.82
    N,N-dimethylaniline 35.05
    acrylonitrile 57.49
    aniline 39.38
    1,3-propanediol 33.3
    bromobenzene 28.89
    dibromomethane 84.85
    1,1,2,2-tetrachloroethane 88.49
    2-methyl-cyclohexyl acetate 50.57
    tetrabutyl urea 29.54
    diisobutyl methanol 16.12
    2-phenylethanol 49.88
    styrene 28.64
    dioctyl adipate 42.44
    dimethyl sulfate 20.95
    ethyl butyrate 80.09
    methyl lactate 24.31
    butyl lactate 39.48
    diethyl carbonate 54.8
    propanediol butyl ether 43.81
    triethyl orthoformate 61.19
    p-tert-butyltoluene 13.15
    methyl 4-tert-butylbenzoate 41.85
    morpholine 138.58
    tert-butylamine 9.7
    n-dodecanol 10.48
    dimethoxymethane 57.49
    ethylene carbonate 43.72
    cyrene 57.06
    2-ethoxyethyl acetate 102.38
    2-ethylhexyl acetate 54.5
    1,2,4-trichlorobenzene 34.46
    4-methylpyridine 74.9
    dibutyl ether 47.27
    2,6-dimethyl-4-heptanol 16.12
    DEF 52.24
    dimethyl isosorbide 140.73
    tetrachloroethylene 45.26
    eugenol 55.03
    triacetin 66.55
    span 80 51.37
    1,4-butanediol 16.12
    1,1-dichloroethane 44.71
    2-methyl-1-pentanol 43.98
    methyl formate 21.1
    2-methyl-1-butanol 36.2
    n-decane 2.36
    butyronitrile 52.64
    3,7-dimethyl-1-octanol 19.41
    1-chlorooctane 11.26
    1-chlorotetradecane 5.85
    n-nonane 1.83
    undecane 1.94
    tert-butylcyclohexane 2.27
    cyclooctane 0.67
    cyclopentanol 24.35
    tetrahydropyran 107.11
    tert-amyl methyl ether 38.17
    2,5,8-trioxanonane 170.46
    1-hexene 13.73
    2-isopropoxyethanol 72.56
    2,2,2-trifluoroethanol 12.52
    methyl butyrate 78.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction