Pyromellitic Acid

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  • Identifiers

    CAS number
    89-05-4

    Molecular formula
    C10H6O8

    SMILES
    C1=C(C(=CC(=C1C(=O)O)C(=O)O)C(=O)O)C(=O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 63.89%
    Sour 42.17%
    Burnt 27.6%
    Phenolic 26.44%
    Nutty 26.29%
    Winey 25.24%
    Balsamic 25.01%
    Clean 23.97%
    Sharp 22.9%
    Aromatic 19.88%

     

    Flavor
    Odorless 63.97%
    Nutty 46.14%
    Very mild 37.28%
    Sour 36.92%
    Mild 36.22%
    Phenolic 32.28%
    Faint 29.15%
    Musty 25.55%
    Caramellic 24.8%
    Urine 22.89%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    0.98 (strong acid)

    Molecular weight
    254.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    469°C

    Melting point expt.

    • 276 °C

    Flash point

    • 294.81 ˚C est.

    Solubility expt.

    • 14000 mg/L (at 16 °C)

  • Synonyms

    • PYROMELLITIC ACID
    • 89-05-4
    • 1,2,4,5-Benzenetetracarboxylic acid
    • Benzene-1,2,4,5-tetracarboxylic acid
    • D9UXG2U6ZU
    • DTXSID8044466
    • NSC-6369
    • DTXCID6024466
    • CHEBI:45165
    • RefChem:177858
    • 201-879-5
    • USAF XR-20
    • MFCD00002471
    • 1,2,4,5-Tetracarboxybenzene
    • 1,2,4,5-Benzene-tetracarboxylic acid
    • C10H6O8
    • NSC 6369
    • EINECS 201-879-5
    • UNII-D9UXG2U6ZU
    • BRN 1887659
    • AI3-28523
    • bmse000771
    • EC 201-879-5
    • 1,4,5-Tetracarboxybenzene
    • SCHEMBL22443
    • 4-09-00-03804 (Beilstein Handbook Reference)
    • WLN: QVR BVQ DVQ EVQ
    • PYROMELLITIC ACID [MI]
    • SCHEMBL8838390
    • CHEMBL1235346
    • 1,2,4,5-benzenetetracarboxylic
    • NSC6369
    • BDBM512625
    • 1,4,5-Benzenetetracarboxylic acid
    • 1,2,4,5-benzenetetracarboxylicacid
    • Tox21_302030
    • EBC-14369
    • SBB060548
    • AKOS004114682
    • 1,2,4,5-benzene tetracarboxylic acid
    • DB02749
    • CAS-89-05-4
    • NCGC00255745-01
    • AC-10249
    • AS-14280
    • DB-078292
    • 1,2,4,5-Benzenetetracarboxylic acid, 96%
    • B0039
    • CS-0128778
    • NS00007494
    • ST50825959
    • EN300-24939
    • AE-562/43282615
    • F212113
    • Q3453375
    • Z203045292
    • InChI=1/C10H6O8/c11-7(12)3-1-4(8(13)14)6(10(17)18)2-5(3)9(15)16/h1-2H,(H,11,12)(H,13,14)(H,15,16)(H,17,18
    • 89-05-4

  • Applications

    Pyromellitic acid is a tetrafunctional aromatic carboxylic acid used mainly as a building block in polymer chemistry: it acts as a multifunctional monomer or crosslinking unit for high-temperature polymers such as polyimides and aromatic polyesters. It is a key intermediate for the production of pyromellitic dianhydride (PMDA), a widely used dianhydride monomer for polyimide resins and high-temperature coatings. It is employed in specialty coatings and electronic materials as part of resin formulations due to its rigid benzene core and multiple carboxyl groups. It can function as a chelating agent in metal-containing formulations to stabilize metal ions. It is used in the synthesis of advanced materials and specialty adhesives in industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 40.01
    methanol 111.06
    isopropanol 16.69
    water 31.66
    ethyl acetate 1.58
    n-propanol 19.49
    acetone 2.97
    n-butanol 6.68
    acetonitrile 0.96
    DMF 133.78
    toluene 0.51
    isobutanol 5.28
    1,4-dioxane 8.38
    methyl acetate 3.17
    THF 14.15
    2-butanone 5.63
    n-pentanol 2.5
    sec-butanol 12.5
    n-hexane 0.27
    ethylene glycol 47.34
    NMP 52.35
    cyclohexane 0.3
    DMSO 316.41
    n-butyl acetate 0.85
    n-octanol 3.42
    chloroform 0.18
    n-propyl acetate 0.39
    acetic acid 1.33
    dichloromethane 0.6
    cyclohexanone 1.41
    propylene glycol 21.74
    isopropyl acetate 0.64
    DMAc 96.59
    2-ethoxyethanol 21.32
    isopentanol 2.38
    n-heptane 0.48
    ethyl formate 1.28
    1,2-dichloroethane 1.03
    n-hexanol 3.02
    2-methoxyethanol 84.0
    isobutyl acetate 0.04
    tetrachloromethane 0.17
    n-pentyl acetate 0.98
    transcutol 13.45
    n-heptanol 3.56
    ethylbenzene 0.32
    MIBK 0.59
    2-propoxyethanol 17.81
    tert-butanol 11.2
    MTBE 3.9
    2-butoxyethanol 8.93
    propionic acid 4.2
    o-xylene 0.92
    formic acid 19.52
    diethyl ether 9.09
    m-xylene 0.32
    p-xylene 0.15
    chlorobenzene 0.05
    dimethyl carbonate 4.48
    n-octane 0.24
    formamide 65.47
    cyclopentanone 3.96
    2-pentanone 2.09
    anisole 0.96
    cyclopentyl methyl ether 4.35
    gamma-butyrolactone 4.66
    1-methoxy-2-propanol 46.16
    pyridine 4.07
    3-pentanone 3.55
    furfural 2.81
    n-dodecane 0.11
    diethylene glycol 22.32
    diisopropyl ether 0.79
    tert-amyl alcohol 11.17
    acetylacetone 0.98
    n-hexadecane 0.12
    acetophenone 0.78
    methyl propionate 6.09
    isopentyl acetate 0.36
    trichloroethylene 0.39
    n-nonanol 3.0
    cyclohexanol 2.28
    benzyl alcohol 1.02
    2-ethylhexanol 0.89
    isooctanol 1.37
    dipropyl ether 3.23
    1,2-dichlorobenzene 0.08
    ethyl lactate 1.46
    propylene carbonate 0.64
    n-methylformamide 47.1
    2-pentanol 4.08
    n-pentane 0.62
    1-propoxy-2-propanol 9.83
    1-methoxy-2-propyl acetate 2.09
    2-(2-methoxypropoxy) propanol 4.64
    mesitylene 0.24
    ε-caprolactone 1.55
    p-cymene 0.36
    epichlorohydrin 4.37
    1,1,1-trichloroethane 0.08
    2-aminoethanol 52.36
    morpholine-4-carbaldehyde 20.66
    sulfolane 16.09
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 5.37
    n-hexyl acetate 1.38
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 7.0
    sec-butyl acetate 0.17
    tert-butyl acetate 0.81
    decalin 0.08
    glycerin 33.86
    diglyme 13.8
    acrylic acid 3.79
    isopropyl myristate 0.48
    n-butyric acid 1.4
    acetyl acetate 0.22
    di(2-ethylhexyl) phthalate 0.49
    ethyl propionate 0.96
    nitromethane 3.66
    1,2-diethoxyethane 2.93
    benzonitrile 0.16
    trioctyl phosphate 0.66
    1-bromopropane 0.86
    gamma-valerolactone 5.05
    n-decanol 1.97
    triethyl phosphate 0.74
    4-methyl-2-pentanol 0.91
    propionitrile 1.36
    vinylene carbonate 0.51
    1,1,2-trichlorotrifluoroethane 5.07
    DMS 1.18
    cumene 0.19
    2-octanol 2.02
    2-hexanone 0.54
    octyl acetate 0.91
    limonene 0.58
    1,2-dimethoxyethane 17.11
    ethyl orthosilicate 0.69
    tributyl phosphate 0.44
    diacetone alcohol 3.34
    N,N-dimethylaniline 1.85
    acrylonitrile 1.97
    aniline 1.67
    1,3-propanediol 27.53
    bromobenzene 0.04
    dibromomethane 0.37
    1,1,2,2-tetrachloroethane 0.77
    2-methyl-cyclohexyl acetate 0.29
    tetrabutyl urea 1.55
    diisobutyl methanol 0.57
    2-phenylethanol 1.05
    styrene 0.22
    dioctyl adipate 0.57
    dimethyl sulfate 11.25
    ethyl butyrate 0.65
    methyl lactate 9.91
    butyl lactate 1.74
    diethyl carbonate 0.45
    propanediol butyl ether 6.05
    triethyl orthoformate 0.84
    p-tert-butyltoluene 0.41
    methyl 4-tert-butylbenzoate 2.48
    morpholine 21.28
    tert-butylamine 5.18
    n-dodecanol 1.22
    dimethoxymethane 58.92
    ethylene carbonate 0.41
    cyrene 2.77
    2-ethoxyethyl acetate 1.71
    2-ethylhexyl acetate 0.3
    1,2,4-trichlorobenzene 0.13
    4-methylpyridine 1.57
    dibutyl ether 1.14
    2,6-dimethyl-4-heptanol 0.57
    DEF 12.95
    dimethyl isosorbide 4.2
    tetrachloroethylene 1.03
    eugenol 2.4
    triacetin 1.01
    span 80 2.67
    1,4-butanediol 7.24
    1,1-dichloroethane 0.18
    2-methyl-1-pentanol 1.02
    methyl formate 11.5
    2-methyl-1-butanol 3.8
    n-decane 0.26
    butyronitrile 0.62
    3,7-dimethyl-1-octanol 1.04
    1-chlorooctane 0.62
    1-chlorotetradecane 0.19
    n-nonane 0.27
    undecane 0.17
    tert-butylcyclohexane 0.05
    cyclooctane 0.18
    cyclopentanol 4.83
    tetrahydropyran 3.73
    tert-amyl methyl ether 5.3
    2,5,8-trioxanonane 8.03
    1-hexene 0.51
    2-isopropoxyethanol 4.88
    2,2,2-trifluoroethanol 2.07
    methyl butyrate 0.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction