Pyridine, 4-ethyl-3-methyl-

Overview IFRA Request a quote

  • Identifiers

    CAS number
    20815-29-6

    Molecular formula
    C8H11N

    SMILES
    CCC1=C(C=NC=C1)C

  • Odor profile

    Fragrance
    Green 74.99%
    Earthy 68.67%
    Nutty 53.01%
    Herbal 47.58%
    Sweet 45.66%
    Musty 44.13%
    Tobacco 42.9%
    Roasted 42.87%
    Animal 42.49%
    Leathery 38.18%

     

    Flavor
    Nutty 63.07%
    Woody 55.14%
    Earthy 54.11%
    Green 51.35%
    Spicy 48.46%
    Musty 42.55%
    Herbal 42.03%
    Tobacco 36.42%
    Citrus 36.33%
    Roasted 36.19%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    6.08 (neutral)

    Molecular weight
    121.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    194°C

    Flash point

    • 64.07 ˚C est.

  • Synonyms

    • 4-Ethyl-3-methylpyridine
    • 20815-29-6
    • 3-METHYL-4-ETHYL PYRIDINE
    • Pyridine, 4-ethyl-3-methyl-
    • 3-methyl-4-ethylpyridine
    • EINECS 244-057-1
    • DTXSID6066656
    • 3-Picoline, 4-ethyl-
    • 3-methyl 4-ethylpyridine
    • 4-ethyl-3-methyl-pyridine
    • SCHEMBL214076
    • DTXCID6036384
    • AKOS006281476
    • NS00026744
    • 244-057-1

  • Applications

    Pyridine, 4-ethyl-3-methyl- (CAS number: 20815-29-6) is used chiefly as an intermediate and building block in industrial synthesis: it serves in the production of pharmaceutical and agrochemical intermediates, enabling the construction of biologically active molecules; it also provides precursors for dyes and pigments as well as building blocks for specialty polymers. The compound can function as a ligand or precursor in metal-catalyzed processes, supporting various cross-coupling and polymerization reactions. In fragrance and flavor chemistry, substituted pyridines may be evaluated as odorant components or perfumery ingredients, subject to formulation constraints and regulations. Overall, applications depend on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 534.22
    methanol 691.28
    isopropanol 249.52
    water 1.26
    ethyl acetate 603.29
    n-propanol 441.74
    acetone 341.73
    n-butanol 436.77
    acetonitrile 516.72
    DMF 434.78
    toluene 420.29
    isobutanol 269.61
    1,4-dioxane 1096.75
    methyl acetate 434.05
    THF 781.86
    2-butanone 392.5
    n-pentanol 268.82
    sec-butanol 222.47
    n-hexane 70.54
    ethylene glycol 64.51
    NMP 394.4
    cyclohexane 127.62
    DMSO 429.3
    n-butyl acetate 783.76
    n-octanol 95.16
    chloroform 1851.48
    n-propyl acetate 320.97
    acetic acid 426.56
    dichloromethane 1983.33
    cyclohexanone 765.06
    propylene glycol 56.28
    isopropyl acetate 276.03
    DMAc 262.19
    2-ethoxyethanol 293.78
    isopentanol 327.7
    n-heptane 77.41
    ethyl formate 427.13
    1,2-dichloroethane 1227.68
    n-hexanol 490.28
    2-methoxyethanol 512.68
    isobutyl acetate 183.86
    tetrachloromethane 464.0
    n-pentyl acetate 241.99
    transcutol 1093.53
    n-heptanol 141.53
    ethylbenzene 127.88
    MIBK 199.09
    2-propoxyethanol 594.5
    tert-butanol 305.67
    MTBE 375.14
    2-butoxyethanol 242.33
    propionic acid 326.67
    o-xylene 187.23
    formic acid 204.31
    diethyl ether 744.19
    m-xylene 206.87
    p-xylene 153.81
    chlorobenzene 673.1
    dimethyl carbonate 129.0
    n-octane 23.57
    formamide 264.1
    cyclopentanone 584.51
    2-pentanone 355.11
    anisole 269.7
    cyclopentyl methyl ether 457.77
    gamma-butyrolactone 717.19
    1-methoxy-2-propanol 265.9
    pyridine 929.01
    3-pentanone 332.93
    furfural 687.21
    n-dodecane 14.15
    diethylene glycol 285.49
    diisopropyl ether 140.33
    tert-amyl alcohol 255.02
    acetylacetone 294.17
    n-hexadecane 16.83
    acetophenone 206.77
    methyl propionate 359.98
    isopentyl acetate 496.16
    trichloroethylene 1676.9
    n-nonanol 87.74
    cyclohexanol 311.56
    benzyl alcohol 198.32
    2-ethylhexanol 263.11
    isooctanol 112.51
    dipropyl ether 382.81
    1,2-dichlorobenzene 482.66
    ethyl lactate 84.04
    propylene carbonate 399.36
    n-methylformamide 384.58
    2-pentanol 211.62
    n-pentane 76.31
    1-propoxy-2-propanol 363.82
    1-methoxy-2-propyl acetate 395.64
    2-(2-methoxypropoxy) propanol 174.29
    mesitylene 122.98
    ε-caprolactone 609.54
    p-cymene 113.08
    epichlorohydrin 941.11
    1,1,1-trichloroethane 1015.07
    2-aminoethanol 160.74
    morpholine-4-carbaldehyde 541.86
    sulfolane 640.67
    2,2,4-trimethylpentane 37.76
    2-methyltetrahydrofuran 694.69
    n-hexyl acetate 235.9
    isooctane 29.18
    2-(2-butoxyethoxy)ethanol 265.69
    sec-butyl acetate 180.76
    tert-butyl acetate 261.58
    decalin 50.32
    glycerin 88.79
    diglyme 524.22
    acrylic acid 252.93
    isopropyl myristate 89.2
    n-butyric acid 597.72
    acetyl acetate 286.79
    di(2-ethylhexyl) phthalate 91.37
    ethyl propionate 256.5
    nitromethane 629.8
    1,2-diethoxyethane 649.08
    benzonitrile 380.48
    trioctyl phosphate 64.1
    1-bromopropane 732.95
    gamma-valerolactone 837.13
    n-decanol 67.62
    triethyl phosphate 120.48
    4-methyl-2-pentanol 115.03
    propionitrile 497.37
    vinylene carbonate 464.45
    1,1,2-trichlorotrifluoroethane 439.89
    DMS 194.63
    cumene 88.84
    2-octanol 84.05
    2-hexanone 271.04
    octyl acetate 114.67
    limonene 185.08
    1,2-dimethoxyethane 571.47
    ethyl orthosilicate 135.21
    tributyl phosphate 90.91
    diacetone alcohol 211.48
    N,N-dimethylaniline 138.58
    acrylonitrile 506.83
    aniline 457.61
    1,3-propanediol 265.88
    bromobenzene 730.49
    dibromomethane 1310.02
    1,1,2,2-tetrachloroethane 1135.52
    2-methyl-cyclohexyl acetate 202.31
    tetrabutyl urea 104.34
    diisobutyl methanol 121.42
    2-phenylethanol 305.71
    styrene 199.29
    dioctyl adipate 115.5
    dimethyl sulfate 167.29
    ethyl butyrate 395.27
    methyl lactate 98.06
    butyl lactate 127.84
    diethyl carbonate 229.44
    propanediol butyl ether 117.17
    triethyl orthoformate 236.57
    p-tert-butyltoluene 106.63
    methyl 4-tert-butylbenzoate 148.2
    morpholine 1023.02
    tert-butylamine 230.04
    n-dodecanol 53.83
    dimethoxymethane 405.53
    ethylene carbonate 422.93
    cyrene 147.48
    2-ethoxyethyl acetate 359.25
    2-ethylhexyl acetate 417.3
    1,2,4-trichlorobenzene 508.58
    4-methylpyridine 791.13
    dibutyl ether 200.98
    2,6-dimethyl-4-heptanol 121.42
    DEF 448.64
    dimethyl isosorbide 347.79
    tetrachloroethylene 954.06
    eugenol 163.19
    triacetin 154.19
    span 80 152.99
    1,4-butanediol 86.29
    1,1-dichloroethane 997.04
    2-methyl-1-pentanol 230.2
    methyl formate 275.71
    2-methyl-1-butanol 289.11
    n-decane 24.53
    butyronitrile 536.16
    3,7-dimethyl-1-octanol 109.64
    1-chlorooctane 105.74
    1-chlorotetradecane 41.16
    n-nonane 24.77
    undecane 17.66
    tert-butylcyclohexane 48.64
    cyclooctane 41.44
    cyclopentanol 261.44
    tetrahydropyran 958.46
    tert-amyl methyl ether 259.39
    2,5,8-trioxanonane 314.08
    1-hexene 221.51
    2-isopropoxyethanol 187.7
    2,2,2-trifluoroethanol 141.59
    methyl butyrate 341.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction