Pyrazine, (2-methylpropyl)-

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  • Identifiers

    CAS number
    29460-92-2

    Molecular formula
    C8H12N2

    SMILES
    CC(C)CC1=NC=CN=C1

  • Odor profile

    Fragrance
    Green 90.65%
    Fruity 60.5%
    Earthy 55.55%
    Vegetable 55.42%
    Nutty 50.87%
    Leafy 37.84%
    Woody 33.83%
    Roasted 33.66%
    Musty 33.13%
    Cocoa 31.01%

     

    Flavor
    Green 87.6%
    Herbal 48.85%
    Earthy 48.6%
    Pepper 46.87%
    Vegetable 38.21%
    Pea 35.3%
    Earth 34.23%
    Musty 32.73%
    Raw 31.85%
    Nutty 29.23%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    4.49 (weak acid)

    Molecular weight
    136.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    213°C

    Flash point

    • 81.06 ˚C est.

  • Synonyms

    • 2-ISOBUTYLPYRAZINE
    • 29460-92-2
    • 2-(2-methylpropyl)pyrazine
    • Isobutylpyrazine
    • Pyrazine, (2-methylpropyl)-
    • (2-Methylpropyl)pyrazine
    • Pyrazine, 2-(2-methylpropyl)-
    • 2-Isobutyl pyrazine
    • EINECS 249-647-2
    • 2-Isobutyl-pyrazine
    • MFCD00156150
    • SCHEMBL510583
    • CHEMBL317788
    • SCHEMBL24317804
    • SCHEMBL25619094
    • DTXSID80183668
    • AKOS006227754
    • AC-16632
    • DB-068120
    • NS00050465

  • Applications

    Pyrazine, (2-methylpropyl)-, CAS 29460-92-2, is primarily used as an odorant and fragrance ingredient in perfumery, often contributing dry, nutty-type notes characteristic of the pyrazine family; it may also serve as a fragrance component in cosmetics and personal care products; it can function as an odorant additive in household products such as cleaners and air fresheners; in industrial manufacturing it acts as an intermediate in the synthesis of specialty chemicals; and in polymers and plastics it may be employed as a precursor or additive to impart fragrance or to influence processing and material properties. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 75.55
    methanol 95.98
    isopropanol 47.2
    water 1.11
    ethyl acetate 33.46
    n-propanol 64.6
    acetone 57.95
    n-butanol 59.37
    acetonitrile 41.77
    DMF 152.51
    toluene 39.96
    isobutanol 56.08
    1,4-dioxane 85.36
    methyl acetate 38.47
    THF 145.69
    2-butanone 47.38
    n-pentanol 42.72
    sec-butanol 46.87
    n-hexane 9.32
    ethylene glycol 41.92
    NMP 181.38
    cyclohexane 24.67
    DMSO 145.16
    n-butyl acetate 86.39
    n-octanol 37.71
    chloroform 287.24
    n-propyl acetate 31.89
    acetic acid 132.81
    dichloromethane 220.18
    cyclohexanone 137.16
    propylene glycol 58.35
    isopropyl acetate 21.74
    DMAc 99.82
    2-ethoxyethanol 46.71
    isopentanol 48.91
    n-heptane 22.96
    ethyl formate 49.37
    1,2-dichloroethane 101.84
    n-hexanol 118.1
    2-methoxyethanol 88.74
    isobutyl acetate 27.9
    tetrachloromethane 49.57
    n-pentyl acetate 35.43
    transcutol 151.84
    n-heptanol 42.21
    ethylbenzene 23.89
    MIBK 26.1
    2-propoxyethanol 121.22
    tert-butanol 57.45
    MTBE 30.09
    2-butoxyethanol 58.34
    propionic acid 84.75
    o-xylene 33.93
    formic acid 46.53
    diethyl ether 23.75
    m-xylene 32.64
    p-xylene 35.77
    chlorobenzene 86.92
    dimethyl carbonate 23.34
    n-octane 6.22
    formamide 37.81
    cyclopentanone 148.04
    2-pentanone 36.15
    anisole 37.39
    cyclopentyl methyl ether 66.73
    gamma-butyrolactone 164.68
    1-methoxy-2-propanol 63.68
    pyridine 117.35
    3-pentanone 31.11
    furfural 187.66
    n-dodecane 5.76
    diethylene glycol 96.49
    diisopropyl ether 9.78
    tert-amyl alcohol 49.03
    acetylacetone 42.24
    n-hexadecane 6.37
    acetophenone 47.52
    methyl propionate 37.38
    isopentyl acetate 72.09
    trichloroethylene 229.65
    n-nonanol 33.74
    cyclohexanol 76.56
    benzyl alcohol 51.05
    2-ethylhexanol 73.04
    isooctanol 32.17
    dipropyl ether 51.41
    1,2-dichlorobenzene 86.01
    ethyl lactate 34.11
    propylene carbonate 121.79
    n-methylformamide 69.03
    2-pentanol 31.19
    n-pentane 8.77
    1-propoxy-2-propanol 98.07
    1-methoxy-2-propyl acetate 67.11
    2-(2-methoxypropoxy) propanol 70.91
    mesitylene 22.05
    ε-caprolactone 106.57
    p-cymene 38.93
    epichlorohydrin 128.6
    1,1,1-trichloroethane 106.04
    2-aminoethanol 65.75
    morpholine-4-carbaldehyde 140.1
    sulfolane 229.64
    2,2,4-trimethylpentane 8.57
    2-methyltetrahydrofuran 93.0
    n-hexyl acetate 52.43
    isooctane 5.42
    2-(2-butoxyethoxy)ethanol 80.65
    sec-butyl acetate 20.45
    tert-butyl acetate 27.81
    decalin 12.69
    glycerin 72.52
    diglyme 111.28
    acrylic acid 93.41
    isopropyl myristate 25.43
    n-butyric acid 95.25
    acetyl acetate 29.57
    di(2-ethylhexyl) phthalate 45.92
    ethyl propionate 26.16
    nitromethane 96.42
    1,2-diethoxyethane 43.45
    benzonitrile 86.67
    trioctyl phosphate 31.45
    1-bromopropane 57.22
    gamma-valerolactone 161.66
    n-decanol 28.49
    triethyl phosphate 37.6
    4-methyl-2-pentanol 22.3
    propionitrile 50.63
    vinylene carbonate 120.96
    1,1,2-trichlorotrifluoroethane 157.68
    DMS 45.41
    cumene 22.78
    2-octanol 25.14
    2-hexanone 35.3
    octyl acetate 36.74
    limonene 58.71
    1,2-dimethoxyethane 65.96
    ethyl orthosilicate 36.24
    tributyl phosphate 36.0
    diacetone alcohol 47.46
    N,N-dimethylaniline 37.49
    acrylonitrile 66.74
    aniline 64.49
    1,3-propanediol 64.2
    bromobenzene 88.77
    dibromomethane 152.05
    1,1,2,2-tetrachloroethane 197.96
    2-methyl-cyclohexyl acetate 60.56
    tetrabutyl urea 49.69
    diisobutyl methanol 35.64
    2-phenylethanol 78.65
    styrene 29.06
    dioctyl adipate 47.41
    dimethyl sulfate 46.95
    ethyl butyrate 50.76
    methyl lactate 44.04
    butyl lactate 49.11
    diethyl carbonate 42.73
    propanediol butyl ether 67.47
    triethyl orthoformate 45.97
    p-tert-butyltoluene 36.72
    methyl 4-tert-butylbenzoate 60.87
    morpholine 99.35
    tert-butylamine 41.3
    n-dodecanol 24.13
    dimethoxymethane 49.74
    ethylene carbonate 87.01
    cyrene 74.21
    2-ethoxyethyl acetate 42.73
    2-ethylhexyl acetate 61.69
    1,2,4-trichlorobenzene 105.56
    4-methylpyridine 97.61
    dibutyl ether 30.77
    2,6-dimethyl-4-heptanol 35.64
    DEF 53.92
    dimethyl isosorbide 123.4
    tetrachloroethylene 138.67
    eugenol 67.42
    triacetin 57.65
    span 80 81.51
    1,4-butanediol 34.43
    1,1-dichloroethane 94.79
    2-methyl-1-pentanol 39.23
    methyl formate 55.94
    2-methyl-1-butanol 50.61
    n-decane 8.05
    butyronitrile 59.16
    3,7-dimethyl-1-octanol 39.19
    1-chlorooctane 27.7
    1-chlorotetradecane 14.46
    n-nonane 7.57
    undecane 6.65
    tert-butylcyclohexane 11.47
    cyclooctane 8.5
    cyclopentanol 92.95
    tetrahydropyran 88.77
    tert-amyl methyl ether 27.87
    2,5,8-trioxanonane 101.46
    1-hexene 26.28
    2-isopropoxyethanol 35.37
    2,2,2-trifluoroethanol 46.13
    methyl butyrate 41.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction