Pterolactam

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  • Identifiers

    CAS number
    38072-88-7

    Molecular formula
    C5H9NO2

    SMILES
    COC1CCC(=O)N1

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 40.82%
    Odorless 37.43%
    Nutty 37.37%
    Roasted 33.05%
    Caramellic 30.84%
    Popcorn 27.72%
    Burnt 26.35%
    Spicy 23.55%
    Savory 20.35%
    Meaty 20.23%

     

    Flavor
    Bitter 55.71%
    Odorless 23.5%
    Cauliflower 21.66%
    Sweet-like 21.47%
    Roasted 21.41%
    Others 20.91%
    Bouillon 20.84%
    Alkaline 20.79%
    Cooked beef juice 20.78%
    Taco 20.68%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    7.73 (neutral)

    Molecular weight
    115.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    274°C

    Melting point expt.

    • 56 - 67 °C

    Flash point

    • 115.88 ˚C est.

  • Synonyms

    • 5-Methoxypyrrolidin-2-one
    • Pterolactam
    • 38072-88-7
    • 2-Pyrrolidinone, 5-methoxy-, (+)-
    • RefChem:177112
    • VULIHENHKGDFAB-UHFFFAOYSA-N
    • 5-Methoxy-2-pyrrolidinone
    • 63853-74-7
    • MFCD00192270
    • (+)-5-Methoxypyrrolidin-2-one
    • 5-methoxy-2-oxo pyrrolidine
    • 5-Methoxybutyrolactam
    • 5-methoxypyrrolidinone
    • 5-methoxy pyrrolidin-2-one
    • 5-Methoxy-2-pyrrolidinone #
    • SCHEMBL441623
    • orb1681829
    • SCHEMBL2036945
    • SCHEMBL2040550
    • SCHEMBL2043440
    • DTXSID20959021
    • CHEBI:173415
    • HY-N1567
    • NBA07288
    • AKOS006272183
    • FG-0405
    • 2-Methoxy-3,4-dihydro-2H-pyrrol-5-ol
    • SY198539
    • DB-296228
    • CS-0017116
    • CS-0255733
    • EN300-204153
    • 5-Methoxy-2-oxopyrrolidine; 5-Methoxy-2-pyrrolidone;
    • 38072-88-7

  • Applications

    Pterolactam (CAS 38072-88-7) is commonly evaluated as an intermediate or building block in chemical synthesis, particularly for the preparation of heterocyclic compounds and pharmaceutical scaffolds; it can serve as a precursor or comonomer in specialty polymers and polyamides; it can function as a reactive monomer or functional additive in coatings and adhesives to introduce amide functionality; it has been explored as a feedstock for high‑performance polymers used in electronics-related materials; and, subject to formulation constraints and local regulations, it is considered for use in general industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 647.6
    methanol 1319.7
    isopropanol 352.99
    water 806.84
    ethyl acetate 126.27
    n-propanol 300.13
    acetone 357.5
    n-butanol 206.9
    acetonitrile 330.77
    DMF 1231.96
    toluene 26.2
    isobutanol 186.68
    1,4-dioxane 220.31
    methyl acetate 179.96
    THF 277.36
    2-butanone 149.43
    n-pentanol 118.62
    sec-butanol 174.9
    n-hexane 1.72
    ethylene glycol 505.19
    NMP 560.29
    cyclohexane 2.21
    DMSO 701.72
    n-butyl acetate 36.36
    n-octanol 34.45
    chloroform 300.19
    n-propyl acetate 41.38
    acetic acid 1184.42
    dichloromethane 307.1
    cyclohexanone 130.56
    propylene glycol 406.45
    isopropyl acetate 60.47
    DMAc 856.11
    2-ethoxyethanol 322.56
    isopentanol 137.26
    n-heptane 1.7
    ethyl formate 208.5
    1,2-dichloroethane 105.53
    n-hexanol 61.97
    2-methoxyethanol 739.94
    isobutyl acetate 26.26
    tetrachloromethane 37.74
    n-pentyl acetate 31.76
    transcutol 312.68
    n-heptanol 32.56
    ethylbenzene 9.19
    MIBK 52.36
    2-propoxyethanol 191.45
    tert-butanol 241.34
    MTBE 74.12
    2-butoxyethanol 100.49
    propionic acid 359.34
    o-xylene 21.19
    formic acid 1695.26
    diethyl ether 60.29
    m-xylene 21.69
    p-xylene 16.26
    chlorobenzene 55.26
    dimethyl carbonate 77.95
    n-octane 0.95
    formamide 1171.65
    cyclopentanone 226.05
    2-pentanone 102.17
    anisole 50.51
    cyclopentyl methyl ether 71.63
    gamma-butyrolactone 325.3
    1-methoxy-2-propanol 382.44
    pyridine 175.28
    3-pentanone 58.2
    furfural 388.01
    n-dodecane 1.2
    diethylene glycol 280.05
    diisopropyl ether 12.44
    tert-amyl alcohol 150.57
    acetylacetone 120.89
    n-hexadecane 1.33
    acetophenone 57.54
    methyl propionate 125.21
    isopentyl acetate 31.21
    trichloroethylene 257.03
    n-nonanol 28.56
    cyclohexanol 87.46
    benzyl alcohol 90.46
    2-ethylhexanol 24.73
    isooctanol 25.22
    dipropyl ether 17.8
    1,2-dichlorobenzene 49.13
    ethyl lactate 54.85
    propylene carbonate 153.54
    n-methylformamide 813.9
    2-pentanol 88.38
    n-pentane 2.75
    1-propoxy-2-propanol 97.83
    1-methoxy-2-propyl acetate 61.54
    2-(2-methoxypropoxy) propanol 85.96
    mesitylene 12.28
    ε-caprolactone 126.14
    p-cymene 9.47
    epichlorohydrin 264.47
    1,1,1-trichloroethane 92.61
    2-aminoethanol 578.02
    morpholine-4-carbaldehyde 441.69
    sulfolane 273.74
    2,2,4-trimethylpentane 2.52
    2-methyltetrahydrofuran 140.8
    n-hexyl acetate 44.12
    isooctane 1.71
    2-(2-butoxyethoxy)ethanol 106.1
    sec-butyl acetate 26.68
    tert-butyl acetate 47.17
    decalin 1.87
    glycerin 534.45
    diglyme 185.23
    acrylic acid 443.92
    isopropyl myristate 14.92
    n-butyric acid 309.87
    acetyl acetate 94.94
    di(2-ethylhexyl) phthalate 27.82
    ethyl propionate 37.76
    nitromethane 994.74
    1,2-diethoxyethane 49.68
    benzonitrile 95.67
    trioctyl phosphate 17.06
    1-bromopropane 46.0
    gamma-valerolactone 347.61
    n-decanol 19.96
    triethyl phosphate 20.82
    4-methyl-2-pentanol 42.02
    propionitrile 148.06
    vinylene carbonate 166.72
    1,1,2-trichlorotrifluoroethane 356.1
    DMS 44.06
    cumene 8.78
    2-octanol 19.85
    2-hexanone 41.48
    octyl acetate 23.18
    limonene 12.95
    1,2-dimethoxyethane 226.22
    ethyl orthosilicate 18.64
    tributyl phosphate 19.9
    diacetone alcohol 104.26
    N,N-dimethylaniline 38.85
    acrylonitrile 238.87
    aniline 107.2
    1,3-propanediol 518.39
    bromobenzene 40.08
    dibromomethane 131.8
    1,1,2,2-tetrachloroethane 168.09
    2-methyl-cyclohexyl acetate 25.25
    tetrabutyl urea 28.72
    diisobutyl methanol 14.54
    2-phenylethanol 56.87
    styrene 13.71
    dioctyl adipate 26.98
    dimethyl sulfate 146.89
    ethyl butyrate 28.66
    methyl lactate 147.12
    butyl lactate 38.72
    diethyl carbonate 22.8
    propanediol butyl ether 109.27
    triethyl orthoformate 23.53
    p-tert-butyltoluene 9.59
    methyl 4-tert-butylbenzoate 55.56
    morpholine 297.83
    tert-butylamine 94.29
    n-dodecanol 14.47
    dimethoxymethane 267.04
    ethylene carbonate 114.38
    cyrene 100.62
    2-ethoxyethyl acetate 53.54
    2-ethylhexyl acetate 22.28
    1,2,4-trichlorobenzene 66.67
    4-methylpyridine 170.03
    dibutyl ether 15.95
    2,6-dimethyl-4-heptanol 14.54
    DEF 180.09
    dimethyl isosorbide 97.87
    tetrachloroethylene 115.22
    eugenol 65.75
    triacetin 56.4
    span 80 64.27
    1,4-butanediol 212.33
    1,1-dichloroethane 130.21
    2-methyl-1-pentanol 79.63
    methyl formate 461.7
    2-methyl-1-butanol 133.63
    n-decane 1.86
    butyronitrile 155.03
    3,7-dimethyl-1-octanol 30.26
    1-chlorooctane 10.1
    1-chlorotetradecane 4.32
    n-nonane 1.6
    undecane 1.43
    tert-butylcyclohexane 2.17
    cyclooctane 0.99
    cyclopentanol 157.16
    tetrahydropyran 93.58
    tert-amyl methyl ether 52.45
    2,5,8-trioxanonane 133.33
    1-hexene 8.64
    2-isopropoxyethanol 142.81
    2,2,2-trifluoroethanol 519.49
    methyl butyrate 59.99

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction