Polyglyceryl-2 Diisostearate

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  • Identifiers

    CAS number
    67938-21-0

    Molecular formula
    C42H82O7

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)OCC(COCC(COC(=O)CCCCCCCCCCCCCCC(C)C)O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 68.68%
    Fatty 48.76%
    Odorless 40.61%
    Oily 37.08%
    Alcoholic 21.7%
    Creamy 19.03%
    Milky 17.29%
    Sweet 17.02%
    Buttery 16.97%
    Savory 15.68%

     

    Flavor
    Waxy 42.17%
    Mild 42.01%
    Bland 40.41%
    Fatty 36.03%
    Oily 35.84%
    Odorless 30.63%
    Faint 29.38%
    Slightly waxy 23.46%
    Bay oil 22.27%
    Beer 22.22%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    14.9

    pKa est.
    10.33 (weak base)

    Molecular weight
    699.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    896°C

    Flash point

    • 268.18 ˚C est.

  • Synonyms

    • Diglyceryl diisostearate
    • DG195GP57P
    • DERMOL DGDIS
    • MATSUNATE DI
    • RISOREX PGIS22
    • CITHROL PG 22IS
    • EINECS 267-821-6
    • SALACOS 42V
    • COSMOL 42V
    • MATSUNATE MI-220
    • SUNSOFT Q-192B
    • DIGLYCERIN DIISOSTEARATE
    • S-FACE IS-202 P
    • Isooctadecanoic acid, diester with diglycerol
    • EC 267-821-6
    • Isooctadecanoic acid, diester with oxybis(propenediol)
    • Di(isooctadecanoic) acid, diester with oxydi(propanediol)
    • ISOOCTADECANOIC ACID, DIESTER WITH OXYBIS(PROPANEDIOL)
    • Isooctadecanoic acid, diester with oxybis[propanediol]
    • RefChem:866530
    • Isooctadecanoic acid, diester with oxybispropanediol
    • 67938-21-0
    • UNII-DG195GP57P
    • SCHEMBL29374796
    • LDDUCKDUDZVHLN-UHFFFAOYSA-N
    • DTXSID301021513
    • Q27276371
    • Di(isooctadecanoic) acid, diester with oxydi(propanedio
    • 67938-21-0

  • Applications

    Polyglyceryl-2 Diisostearate (CAS 67938-21-0) is a nonionic ester primarily used as an emollient and surfactant in cosmetics and personal care, helping to form stable oil-in-water emulsions and provide slip and conditioning in creams, lotions, and hair-care products. It is also employed in household cleaning formulations as a mild surfactant/emulsifier to enhance wetting and spreading. In industrial formulations, it can act as a processing aid and lubricant in coatings, inks, and adhesives, improving dispersion and compatibility. Additionally, it may serve as a plasticizer or compatibility agent in certain polymer systems and as an excipient/emulsifier in topical pharmaceutical preparations. These roles are typical, subject to formulation constraints and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.49
    methanol 2.23
    isopropanol 1.26
    water 0.05
    ethyl acetate 12.93
    n-propanol 2.44
    acetone 10.04
    n-butanol 2.29
    acetonitrile 2.76
    DMF 22.62
    toluene 7.46
    isobutanol 2.09
    1,4-dioxane 14.57
    methyl acetate 10.73
    THF 46.8
    2-butanone 14.61
    n-pentanol 3.06
    sec-butanol 2.82
    n-hexane 0.95
    ethylene glycol 0.41
    NMP 113.03
    cyclohexane 2.2
    DMSO 30.97
    n-butyl acetate 11.8
    n-octanol 5.86
    chloroform 53.11
    n-propyl acetate 14.42
    acetic acid 13.21
    dichloromethane 48.01
    cyclohexanone 44.12
    propylene glycol 1.13
    isopropyl acetate 12.65
    DMAc 75.6
    2-ethoxyethanol 10.14
    isopentanol 2.76
    n-heptane 1.04
    ethyl formate 7.84
    1,2-dichloroethane 22.24
    n-hexanol 2.43
    2-methoxyethanol 8.38
    isobutyl acetate 10.23
    tetrachloromethane 10.23
    n-pentyl acetate 26.62
    transcutol 69.24
    n-heptanol 4.42
    ethylbenzene 6.02
    MIBK 10.91
    2-propoxyethanol 9.69
    tert-butanol 2.54
    MTBE 7.33
    2-butoxyethanol 16.88
    propionic acid 8.32
    o-xylene 8.53
    formic acid 3.98
    diethyl ether 4.38
    m-xylene 6.38
    p-xylene 7.87
    chlorobenzene 12.48
    dimethyl carbonate 9.49
    n-octane 0.74
    formamide 6.19
    cyclopentanone 53.68
    2-pentanone 12.55
    anisole 11.14
    cyclopentyl methyl ether 25.22
    gamma-butyrolactone 62.14
    1-methoxy-2-propanol 9.1
    pyridine 19.21
    3-pentanone 15.07
    furfural 47.0
    n-dodecane 0.42
    diethylene glycol 3.98
    diisopropyl ether 3.0
    tert-amyl alcohol 5.42
    acetylacetone 26.07
    n-hexadecane 0.51
    acetophenone 21.07
    methyl propionate 14.71
    isopentyl acetate 13.7
    trichloroethylene 62.02
    n-nonanol 6.4
    cyclohexanol 7.11
    benzyl alcohol 7.34
    2-ethylhexanol 3.66
    isooctanol 4.93
    dipropyl ether 7.61
    1,2-dichlorobenzene 19.2
    ethyl lactate 11.0
    propylene carbonate 36.59
    n-methylformamide 8.53
    2-pentanol 2.36
    n-pentane 0.53
    1-propoxy-2-propanol 12.11
    1-methoxy-2-propyl acetate 20.11
    2-(2-methoxypropoxy) propanol 22.49
    mesitylene 4.59
    ε-caprolactone 51.58
    p-cymene 4.9
    epichlorohydrin 49.26
    1,1,1-trichloroethane 32.37
    2-aminoethanol 1.3
    morpholine-4-carbaldehyde 52.43
    sulfolane 138.51
    2,2,4-trimethylpentane 1.16
    2-methyltetrahydrofuran 27.95
    n-hexyl acetate 26.92
    isooctane 0.47
    2-(2-butoxyethoxy)ethanol 24.9
    sec-butyl acetate 13.77
    tert-butyl acetate 22.1
    decalin 2.09
    glycerin 2.77
    diglyme 57.99
    acrylic acid 7.76
    isopropyl myristate 7.44
    n-butyric acid 14.47
    acetyl acetate 13.95
    di(2-ethylhexyl) phthalate 9.49
    ethyl propionate 15.15
    nitromethane 27.76
    1,2-diethoxyethane 19.48
    benzonitrile 8.33
    trioctyl phosphate 6.25
    1-bromopropane 10.01
    gamma-valerolactone 81.62
    n-decanol 3.73
    triethyl phosphate 14.85
    4-methyl-2-pentanol 2.28
    propionitrile 3.33
    vinylene carbonate 28.74
    1,1,2-trichlorotrifluoroethane 54.16
    DMS 17.3
    cumene 4.97
    2-octanol 4.46
    2-hexanone 14.49
    octyl acetate 10.42
    limonene 8.04
    1,2-dimethoxyethane 22.86
    ethyl orthosilicate 14.14
    tributyl phosphate 8.92
    diacetone alcohol 20.64
    N,N-dimethylaniline 12.1
    acrylonitrile 4.67
    aniline 6.76
    1,3-propanediol 2.22
    bromobenzene 15.26
    dibromomethane 24.81
    1,1,2,2-tetrachloroethane 63.28
    2-methyl-cyclohexyl acetate 18.34
    tetrabutyl urea 14.17
    diisobutyl methanol 3.03
    2-phenylethanol 6.24
    styrene 5.86
    dioctyl adipate 16.04
    dimethyl sulfate 33.94
    ethyl butyrate 15.75
    methyl lactate 10.71
    butyl lactate 23.41
    diethyl carbonate 9.66
    propanediol butyl ether 14.93
    triethyl orthoformate 18.31
    p-tert-butyltoluene 5.21
    methyl 4-tert-butylbenzoate 34.84
    morpholine 19.68
    tert-butylamine 1.72
    n-dodecanol 2.31
    dimethoxymethane 13.8
    ethylene carbonate 22.72
    cyrene 31.48
    2-ethoxyethyl acetate 36.47
    2-ethylhexyl acetate 12.92
    1,2,4-trichlorobenzene 29.13
    4-methylpyridine 17.8
    dibutyl ether 10.39
    2,6-dimethyl-4-heptanol 3.03
    DEF 23.82
    dimethyl isosorbide 54.48
    tetrachloroethylene 36.41
    eugenol 24.17
    triacetin 46.26
    span 80 18.47
    1,4-butanediol 1.45
    1,1-dichloroethane 17.79
    2-methyl-1-pentanol 4.35
    methyl formate 8.31
    2-methyl-1-butanol 3.51
    n-decane 1.12
    butyronitrile 3.36
    3,7-dimethyl-1-octanol 5.88
    1-chlorooctane 6.25
    1-chlorotetradecane 1.63
    n-nonane 1.01
    undecane 0.64
    tert-butylcyclohexane 1.58
    cyclooctane 1.15
    cyclopentanol 8.2
    tetrahydropyran 16.99
    tert-amyl methyl ether 11.46
    2,5,8-trioxanonane 33.44
    1-hexene 2.77
    2-isopropoxyethanol 8.9
    2,2,2-trifluoroethanol 9.93
    methyl butyrate 21.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction