Phosphorus trichloride

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  • Identifiers

    CAS number
    7719-12-2

    Molecular formula
    Cl3P

    SMILES
    P(Cl)(Cl)Cl

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 53.69%
    Fishy 43.7%
    Sweet 26.97%
    Ripe 21.35%
    Cheesy 18.96%
    Oily 16.5%
    Animal 15.77%
    Fresh 14.46%
    Musty 13.87%
    Clean 13.41%

     

    Flavor
    Odorless 37.9%
    Sulfurous 24.14%
    Sulfury 23.8%
    Fishy 22.58%
    Meaty 21.34%
    Glue 18.73%
    Bloody 18.69%
    Rotten 18.46%
    Mousy 18.25%
    Bouillon 18.17%

     

    Odor impact est.
    High

    Odor threshold

    • Phosphorus trichloride ... can be detected at about 0.5 mg/cu m.

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    -14.43 (strong acid)

    Molecular weight
    137.33 g/mol

    Melting point expt.

    • -170 °F (EPA, 1998)
    • -93.6 °C
    • -112 °C
    • -170 °F

    Boiling point

    • 169 °F at 760 mmHg (EPA, 1998)
    • 76.1 °C
    • 76 °C
    • 169 °F

    Flash point

    • 47.92 ˚C est.

    Solubility expt.

    • Reacts with water (NIOSH, 2024)
    • Reacts with water, ethanol; soluble in benzene, chloroform, ether
    • Soluble in carbon tetrachloride
    • Solubility in water: reaction
    • Reacts

  • Synonyms

    • PHOSPHORUS TRICHLORIDE
    • Phosphorous trichloride
    • trichlorophosphane
    • Trichlorophosphine
    • 7719-12-2
    • Phosphorous chloride
    • PCl3
    • Phosphorus(III) chloride
    • Phosphine, trichloro-
    • Phosphorus chloride (PCl3)
    • Fosfortrichloride
    • Phosphortrichlorid
    • Trojchlorek fosforu
    • Phosphorus chloride (Cl6P2)
    • Fosforo(tricloruro di)
    • Phosphore(trichlorure de)
    • trichloridophosphorus
    • M97C0A6S8U
    • Chloride of phosphorus
    • HSDB 1031
    • EINECS 231-749-3
    • UNII-M97C0A6S8U
    • CHEBI:30334
    • EC 231-749-3
    • (PCl3)
    • [PCl3]
    • Phosphorustrichloride
    • Phosphorus trichloride, ReagentPlus(R), 99%
    • Fosfortrichloride [Dutch]
    • MFCD00011438
    • Phosphortrichlorid [German]
    • Trojchlorek fosforu [Polish]
    • Fosforo(tricloruro di) [Italian]
    • Phosphore(trichlorure de) [French]
    • Phosphorus Chloride; Phosphorous Chloride; Phosphorus Chloride (Cl6P2); Phosphorus Trichloride; Trichlorophosphine;
    • phosphoroustrichloride
    • UN1809
    • phosphorus-trichloride
    • phosphorous tri-chloride
    • Phosphorus(III)chloride
    • Phosphorous(III) chloride
    • Phosphorus trichloride, CP
    • phosphorous (III) chloride
    • phosphorus (III) trichloride
    • DTXSID5029687
    • PHOSPHORUS (III) CHLORIDE
    • PHOSPHORUS CHLORIDE(PCL3)
    • PHOSPHORUS CHLORIDE(CL6P2)
    • PHOSPHORUS TRICHLORIDE [MI]
    • PHOSPHORUS TRICHLORIDE [HSDB]
    • AKOS015904450
    • UN 1809
    • BP-31000
    • NS00113734
    • P1611
    • Phosphorus trichloride [UN1809] [Poison]
    • Phosphorus trichloride, purum, >=97.0% (AT)
    • Q409707
    • Phosphorus trichloride, 99.999% trace metals basis
    • 231-749-3

  • Applications

    Phosphorus trichloride (CAS 7719-12-2) serves as a versatile intermediate in organophosphorus chemistry: it is converted to phosphorus oxychloride (POCl3), which is a key feedstock for manufacturing a broad range of organophosphorus compounds, including flame retardants and polymer stabilizers; it also functions as a chlorinating agent in organic synthesis, enabling alcohol-to-alkyl chloride transformations. POCl3 derived from PCl3 is widely used in semiconductor manufacturing for silicon diffusion processes, and thus PCl3 underpins electronics applications. Additionally, phosphorus trichloride is employed as a starting material for agrochemical synthesis, producing organophosphorus pesticides and related catalysts.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 300.82
    methanol 337.27
    isopropanol 290.94
    water 16.13
    ethyl acetate 200.91
    n-propanol 246.78
    acetone 394.17
    n-butanol 265.67
    acetonitrile 155.78
    DMF 799.61
    toluene 190.02
    isobutanol 195.55
    1,4-dioxane 414.33
    methyl acetate 182.16
    THF 784.75
    2-butanone 252.9
    n-pentanol 167.3
    sec-butanol 248.32
    n-hexane 112.34
    ethylene glycol 124.0
    NMP 582.84
    cyclohexane 168.79
    DMSO 720.37
    n-butyl acetate 158.37
    n-octanol 159.45
    chloroform 472.63
    n-propyl acetate 135.95
    acetic acid 222.78
    dichloromethane 423.5
    cyclohexanone 344.37
    propylene glycol 130.99
    isopropyl acetate 170.39
    DMAc 556.67
    2-ethoxyethanol 253.26
    isopentanol 211.41
    n-heptane 114.36
    ethyl formate 156.42
    1,2-dichloroethane 311.74
    n-hexanol 197.57
    2-methoxyethanol 467.2
    isobutyl acetate 101.43
    tetrachloromethane 194.63
    n-pentyl acetate 162.52
    transcutol 354.66
    n-heptanol 167.29
    ethylbenzene 105.86
    MIBK 189.75
    2-propoxyethanol 304.84
    tert-butanol 352.23
    MTBE 282.72
    2-butoxyethanol 238.62
    propionic acid 150.48
    o-xylene 154.76
    formic acid 118.69
    diethyl ether 344.11
    m-xylene 159.68
    p-xylene 131.9
    chlorobenzene 176.26
    dimethyl carbonate 158.7
    n-octane 64.02
    formamide 180.13
    cyclopentanone 432.24
    2-pentanone 277.49
    anisole 189.47
    cyclopentyl methyl ether 400.6
    gamma-butyrolactone 367.97
    1-methoxy-2-propanol 410.53
    pyridine 289.96
    3-pentanone 216.89
    furfural 361.22
    n-dodecane 45.19
    diethylene glycol 270.7
    diisopropyl ether 157.33
    tert-amyl alcohol 268.91
    acetylacetone 277.11
    n-hexadecane 49.37
    acetophenone 167.58
    methyl propionate 214.89
    isopentyl acetate 140.31
    trichloroethylene 406.79
    n-nonanol 141.8
    cyclohexanol 274.91
    benzyl alcohol 151.65
    2-ethylhexanol 136.5
    isooctanol 137.62
    dipropyl ether 226.36
    1,2-dichlorobenzene 171.36
    ethyl lactate 97.44
    propylene carbonate 201.57
    n-methylformamide 272.6
    2-pentanol 235.3
    n-pentane 155.93
    1-propoxy-2-propanol 251.96
    1-methoxy-2-propyl acetate 177.12
    2-(2-methoxypropoxy) propanol 166.0
    mesitylene 131.37
    ε-caprolactone 255.54
    p-cymene 100.46
    epichlorohydrin 380.47
    1,1,1-trichloroethane 293.36
    2-aminoethanol 170.94
    morpholine-4-carbaldehyde 480.31
    sulfolane 514.48
    2,2,4-trimethylpentane 68.63
    2-methyltetrahydrofuran 440.94
    n-hexyl acetate 178.61
    isooctane 64.79
    2-(2-butoxyethoxy)ethanol 220.55
    sec-butyl acetate 109.07
    tert-butyl acetate 207.86
    decalin 68.88
    glycerin 184.58
    diglyme 372.42
    acrylic acid 143.83
    isopropyl myristate 103.45
    n-butyric acid 215.02
    acetyl acetate 133.78
    di(2-ethylhexyl) phthalate 91.11
    ethyl propionate 136.09
    nitromethane 282.64
    1,2-diethoxyethane 197.82
    benzonitrile 148.64
    trioctyl phosphate 84.87
    1-bromopropane 253.02
    gamma-valerolactone 424.2
    n-decanol 113.2
    triethyl phosphate 96.36
    4-methyl-2-pentanol 147.28
    propionitrile 147.86
    vinylene carbonate 182.75
    1,1,2-trichlorotrifluoroethane 304.32
    DMS 125.38
    cumene 86.39
    2-octanol 148.14
    2-hexanone 167.65
    octyl acetate 124.1
    limonene 145.6
    1,2-dimethoxyethane 393.11
    ethyl orthosilicate 102.23
    tributyl phosphate 81.29
    diacetone alcohol 237.5
    N,N-dimethylaniline 190.08
    acrylonitrile 168.13
    aniline 204.95
    1,3-propanediol 229.97
    bromobenzene 181.93
    dibromomethane 344.21
    1,1,2,2-tetrachloroethane 394.96
    2-methyl-cyclohexyl acetate 123.39
    tetrabutyl urea 125.2
    diisobutyl methanol 118.1
    2-phenylethanol 156.08
    styrene 128.48
    dioctyl adipate 126.0
    dimethyl sulfate 255.59
    ethyl butyrate 140.32
    methyl lactate 157.38
    butyl lactate 128.92
    diethyl carbonate 98.69
    propanediol butyl ether 188.97
    triethyl orthoformate 127.9
    p-tert-butyltoluene 113.77
    methyl 4-tert-butylbenzoate 204.62
    morpholine 449.63
    tert-butylamine 278.37
    n-dodecanol 95.77
    dimethoxymethane 566.48
    ethylene carbonate 158.04
    cyrene 177.84
    2-ethoxyethyl acetate 166.17
    2-ethylhexyl acetate 127.37
    1,2,4-trichlorobenzene 192.16
    4-methylpyridine 298.25
    dibutyl ether 153.37
    2,6-dimethyl-4-heptanol 118.1
    DEF 333.14
    dimethyl isosorbide 277.77
    tetrachloroethylene 306.2
    eugenol 188.5
    triacetin 153.6
    span 80 185.76
    1,4-butanediol 112.11
    1,1-dichloroethane 293.82
    2-methyl-1-pentanol 136.43
    methyl formate 218.06
    2-methyl-1-butanol 195.29
    n-decane 67.66
    butyronitrile 168.28
    3,7-dimethyl-1-octanol 123.91
    1-chlorooctane 124.96
    1-chlorotetradecane 70.27
    n-nonane 71.06
    undecane 53.12
    tert-butylcyclohexane 71.04
    cyclooctane 87.38
    cyclopentanol 318.45
    tetrahydropyran 400.04
    tert-amyl methyl ether 249.61
    2,5,8-trioxanonane 283.1
    1-hexene 166.27
    2-isopropoxyethanol 190.0
    2,2,2-trifluoroethanol 120.72
    methyl butyrate 161.76

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction