Phosphorus pentafluoride

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  • Identifiers

    CAS number
    7647-19-0

    Molecular formula
    F5P

    SMILES
    FP(F)(F)(F)F

    Safety labels

    Compressed Gas
    Compressed Gas

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 55.78%
    Sweet 23.43%
    Fishy 22.17%
    Savory 19.77%
    Sulfurous 19.15%
    Meaty 18.38%
    Clean 15.21%
    Cooling 15.2%
    Fresh 14.77%
    Green 14.61%

     

  • Properties

    XLogP3-AA
    2.7

    pKa est.
    -2.25 (strong acid)

    Molecular weight
    125.9657778 g/mol

    Melting point expt.

    • -93.8 °C

    Boiling point

    • -84.6 °C

    Flash point

    • 2.17 ˚C est.

  • Synonyms

    • PHOSPHORUS PENTAFLUORIDE
    • Pentafluorophosphorane
    • 7647-19-0
    • Phosphorane, pentafluoro-
    • Phosphorus fluoride (PF5)
    • Pentafluorophosphorus
    • Phosphorus(V) fluoride
    • Phosphorus, fluoride, penta-
    • UN2198
    • HSDB 1254
    • EINECS 231-602-3
    • 0OU1ESO71L
    • pentafluoro-lambda5-phosphane
    • pentafluoridophosphorus
    • Phosphorus pentafluoride, compressed
    • pentafluoro-lambda(5)-phosphane
    • DTXSID9064760
    • CHEBI:30202
    • [PF5]
    • PHOSPHORUS PENTAFLUORIDE [MI]
    • UN-2198
    • PF5
    • (PF5)
    • UNII-0OU1ESO71L
    • Pentafluorophosphorane #
    • Phosphorane, pentafluoro
    • Phosphorus, fluoride, penta
    • DTXCID9047883
    • MFCD00040326
    • AKOS015960671
    • pentakis(fluoranyl)-$l^{5}-phosphane
    • UN 2198
    • InChI=1/F5P/c1-6(2,3,4)
    • DB-231675
    • A838720
    • Q414652
    • Phosphorus pentafluoride, compressed [UN2198] [Poison gas]
    • 231-602-3

  • Applications

    Phosphorus pentafluoride (CAS 7647-19-0) is primarily used as a strong fluorinating agent to introduce fluorine into organic substrates, enabling the formation of organofluorine compounds, often as intermediates in the synthesis of fluorinated products for pharmaceuticals, specialty chemicals, and materials. It also serves as a precursor for the synthesis of other phosphorus-fluoride species and related fluorinating reagents. In electronics and semiconductor manufacturing, PF5 participates in surface treatments and fluorination/etching or deposition processes involving fluorine to prepare surfaces or form fluorinated coatings. In polymer chemistry, it can be employed to fluorinate monomers or modify polymers to create fluorinated materials. Additionally, PF5 is used in both research and production at laboratory and industrial scales as a strong Lewis acid and fluorinating reagent for specialized organic transformations, subject to safety regulations and processing conditions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 313.48
    methanol 507.81
    isopropanol 298.35
    water 137.03
    ethyl acetate 100.16
    n-propanol 224.45
    acetone 279.28
    n-butanol 185.38
    acetonitrile 204.03
    DMF 688.63
    toluene 43.81
    isobutanol 149.69
    1,4-dioxane 180.04
    methyl acetate 118.67
    THF 320.77
    2-butanone 138.48
    n-pentanol 113.25
    sec-butanol 205.29
    n-hexane 39.86
    ethylene glycol 227.26
    NMP 331.24
    cyclohexane 48.92
    DMSO 861.96
    n-butyl acetate 59.81
    n-octanol 80.37
    chloroform 150.0
    n-propyl acetate 63.79
    acetic acid 168.3
    dichloromethane 175.79
    cyclohexanone 111.58
    propylene glycol 169.94
    isopropyl acetate 76.87
    DMAc 408.93
    2-ethoxyethanol 213.76
    isopentanol 130.97
    n-heptane 44.28
    ethyl formate 104.62
    1,2-dichloroethane 147.51
    n-hexanol 102.51
    2-methoxyethanol 423.43
    isobutyl acetate 33.65
    tetrachloromethane 53.76
    n-pentyl acetate 60.82
    transcutol 190.32
    n-heptanol 79.2
    ethylbenzene 30.35
    MIBK 86.21
    2-propoxyethanol 186.2
    tert-butanol 318.43
    MTBE 167.51
    2-butoxyethanol 122.8
    propionic acid 130.25
    o-xylene 53.49
    formic acid 209.04
    diethyl ether 211.65
    m-xylene 44.87
    p-xylene 37.01
    chlorobenzene 40.12
    dimethyl carbonate 93.3
    n-octane 21.26
    formamide 327.76
    cyclopentanone 167.55
    2-pentanone 126.88
    anisole 67.58
    cyclopentyl methyl ether 139.11
    gamma-butyrolactone 182.13
    1-methoxy-2-propanol 323.43
    pyridine 111.07
    3-pentanone 106.24
    furfural 153.19
    n-dodecane 16.04
    diethylene glycol 208.23
    diisopropyl ether 75.25
    tert-amyl alcohol 208.93
    acetylacetone 123.45
    n-hexadecane 16.74
    acetophenone 64.24
    methyl propionate 116.11
    isopentyl acetate 50.02
    trichloroethylene 125.3
    n-nonanol 70.36
    cyclohexanol 122.69
    benzyl alcohol 69.36
    2-ethylhexanol 59.55
    isooctanol 60.29
    dipropyl ether 107.55
    1,2-dichlorobenzene 43.61
    ethyl lactate 69.96
    propylene carbonate 84.41
    n-methylformamide 309.43
    2-pentanol 152.28
    n-pentane 76.34
    1-propoxy-2-propanol 137.35
    1-methoxy-2-propyl acetate 78.52
    2-(2-methoxypropoxy) propanol 99.32
    mesitylene 40.99
    ε-caprolactone 89.97
    p-cymene 38.39
    epichlorohydrin 162.05
    1,1,1-trichloroethane 90.36
    2-aminoethanol 252.5
    morpholine-4-carbaldehyde 258.46
    sulfolane 278.5
    2,2,4-trimethylpentane 26.67
    2-methyltetrahydrofuran 164.33
    n-hexyl acetate 69.26
    isooctane 21.32
    2-(2-butoxyethoxy)ethanol 121.25
    sec-butyl acetate 42.04
    tert-butyl acetate 86.75
    decalin 16.61
    glycerin 235.86
    diglyme 200.69
    acrylic acid 126.48
    isopropyl myristate 43.69
    n-butyric acid 114.87
    acetyl acetate 59.37
    di(2-ethylhexyl) phthalate 39.47
    ethyl propionate 69.32
    nitromethane 256.59
    1,2-diethoxyethane 92.42
    benzonitrile 55.38
    trioctyl phosphate 38.46
    1-bromopropane 112.03
    gamma-valerolactone 177.74
    n-decanol 57.26
    triethyl phosphate 45.56
    4-methyl-2-pentanol 85.06
    propionitrile 130.52
    vinylene carbonate 76.06
    1,1,2-trichlorotrifluoroethane 152.44
    DMS 58.85
    cumene 29.31
    2-octanol 68.1
    2-hexanone 70.2
    octyl acetate 50.86
    limonene 51.39
    1,2-dimethoxyethane 282.53
    ethyl orthosilicate 46.76
    tributyl phosphate 37.28
    diacetone alcohol 132.73
    N,N-dimethylaniline 79.5
    acrylonitrile 149.26
    aniline 81.28
    1,3-propanediol 232.85
    bromobenzene 35.73
    dibromomethane 145.51
    1,1,2,2-tetrachloroethane 140.98
    2-methyl-cyclohexyl acetate 49.48
    tetrabutyl urea 63.04
    diisobutyl methanol 54.21
    2-phenylethanol 64.61
    styrene 32.87
    dioctyl adipate 50.27
    dimethyl sulfate 154.18
    ethyl butyrate 61.75
    methyl lactate 119.41
    butyl lactate 64.17
    diethyl carbonate 45.7
    propanediol butyl ether 118.58
    triethyl orthoformate 55.1
    p-tert-butyltoluene 41.99
    methyl 4-tert-butylbenzoate 90.26
    morpholine 218.28
    tert-butylamine 233.4
    n-dodecanol 48.08
    dimethoxymethane 385.68
    ethylene carbonate 67.41
    cyrene 91.89
    2-ethoxyethyl acetate 65.81
    2-ethylhexyl acetate 41.15
    1,2,4-trichlorobenzene 49.86
    4-methylpyridine 101.72
    dibutyl ether 63.01
    2,6-dimethyl-4-heptanol 54.21
    DEF 177.47
    dimethyl isosorbide 127.51
    tetrachloroethylene 114.93
    eugenol 93.0
    triacetin 68.16
    span 80 85.83
    1,4-butanediol 109.75
    1,1-dichloroethane 122.12
    2-methyl-1-pentanol 78.32
    methyl formate 204.2
    2-methyl-1-butanol 126.89
    n-decane 23.49
    butyronitrile 112.87
    3,7-dimethyl-1-octanol 61.77
    1-chlorooctane 47.57
    1-chlorotetradecane 25.85
    n-nonane 24.48
    undecane 18.77
    tert-butylcyclohexane 16.91
    cyclooctane 23.55
    cyclopentanol 158.34
    tetrahydropyran 143.07
    tert-amyl methyl ether 138.0
    2,5,8-trioxanonane 158.69
    1-hexene 64.59
    2-isopropoxyethanol 133.0
    2,2,2-trifluoroethanol 109.91
    methyl butyrate 80.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction