Phenoxyethylparaben

Overview IFRA Request a quote

  • Identifiers

    CAS number
    55468-88-7

    Molecular formula
    C15H14O4

    SMILES
    C1=CC=C(C=C1)OCCOC(=O)C2=CC=C(C=C2)O

    Safety labels

  • Odor profile

    Fragrance
    Balsamic 61.17%
    Floral 61.17%
    Sweet 53.43%
    Phenolic 44.92%
    Honey 35.57%
    Powdery 34.12%
    Spicy 34.01%
    Aromatic 33.48%
    Vanilla 28.8%
    Animal 28.69%

     

    Flavor
    Balsam 62.32%
    Sweet 53.61%
    Bitter 50.35%
    Floral 48.77%
    Wintergreen 39.79%
    Herbal 36.67%
    Balsamic 35.06%
    Powdery 33.79%
    Faint 31.23%
    Flower 29.85%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.63 (neutral)

    Molecular weight
    258.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    438°C

    Flash point

    • 189.65 ˚C est.

  • Synonyms

    • Phenoxyethylparaben
    • 55468-88-7
    • 2-phenoxyethyl 4-hydroxybenzoate
    • 2-Phenoxyethyl p-hydroxybenzoate
    • MFCD00017631
    • Undebenzophene
    • phenoxyethyl paraben
    • EINECS 259-654-2
    • SCHEMBL160688
    • 2-phenoxyethyl4-hydroxybenzoate
    • DTXSID70204033
    • GGPOVLCFVFOVDF-UHFFFAOYSA-N
    • AKOS016402715
    • FP67915
    • DB-293317
    • 576E45366K
    • CS-0089090
    • NS00013973
    • D74821
    • Benzoic acid, 4-hydroxy-, 2-phenoxyethyl ester
    • P-HYDROXYBENZOIC ACID, PHENOXYETHYL ESTER
    • Q27261471
    • 55468-88-7

  • Applications

    Phenoxyethylparaben (CAS 55468-88-7) is primarily used as a preservative in cosmetics and personal care products to inhibit microbial growth in creams, lotions, shampoos, and makeup. It is also employed as a preservative in pharmaceutical formulations, particularly topical products, to extend shelf life. In some household cleaning products it may be used to maintain stability and reduce microbial contamination, and it can appear as an additive in polymer or coatings formulations to improve preservative performance in certain systems. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 37.47
    methanol 59.1
    isopropanol 24.06
    water 0.21
    ethyl acetate 121.76
    n-propanol 30.19
    acetone 190.18
    n-butanol 23.12
    acetonitrile 111.25
    DMF 200.49
    toluene 17.92
    isobutanol 17.15
    1,4-dioxane 160.26
    methyl acetate 133.66
    THF 422.35
    2-butanone 143.29
    n-pentanol 26.67
    sec-butanol 37.86
    n-hexane 0.85
    ethylene glycol 19.66
    NMP 140.91
    cyclohexane 0.91
    DMSO 1014.48
    n-butyl acetate 57.99
    n-octanol 11.96
    chloroform 150.51
    n-propyl acetate 74.42
    acetic acid 102.67
    dichloromethane 291.64
    cyclohexanone 123.26
    propylene glycol 24.67
    isopropyl acetate 60.53
    DMAc 343.18
    2-ethoxyethanol 124.63
    isopentanol 24.17
    n-heptane 1.72
    ethyl formate 53.72
    1,2-dichloroethane 214.05
    n-hexanol 19.62
    2-methoxyethanol 146.37
    isobutyl acetate 32.22
    tetrachloromethane 5.89
    n-pentyl acetate 28.85
    transcutol 604.38
    n-heptanol 11.36
    ethylbenzene 13.57
    MIBK 51.49
    2-propoxyethanol 79.94
    tert-butanol 50.52
    MTBE 58.36
    2-butoxyethanol 43.5
    propionic acid 57.63
    o-xylene 15.31
    formic acid 61.46
    diethyl ether 68.17
    m-xylene 11.75
    p-xylene 15.74
    chlorobenzene 34.39
    dimethyl carbonate 75.27
    n-octane 0.83
    formamide 234.33
    cyclopentanone 224.86
    2-pentanone 86.94
    anisole 69.69
    cyclopentyl methyl ether 80.49
    gamma-butyrolactone 291.47
    1-methoxy-2-propanol 99.33
    pyridine 107.25
    3-pentanone 79.85
    furfural 195.43
    n-dodecane 1.14
    diethylene glycol 82.01
    diisopropyl ether 14.58
    tert-amyl alcohol 55.06
    acetylacetone 176.87
    n-hexadecane 1.33
    acetophenone 73.17
    methyl propionate 105.19
    isopentyl acetate 53.06
    trichloroethylene 320.18
    n-nonanol 12.94
    cyclohexanol 25.11
    benzyl alcohol 44.26
    2-ethylhexanol 17.55
    isooctanol 11.59
    dipropyl ether 39.36
    1,2-dichlorobenzene 40.27
    ethyl lactate 44.76
    propylene carbonate 95.44
    n-methylformamide 112.21
    2-pentanol 20.1
    n-pentane 0.51
    1-propoxy-2-propanol 62.56
    1-methoxy-2-propyl acetate 86.29
    2-(2-methoxypropoxy) propanol 89.27
    mesitylene 8.4
    ε-caprolactone 108.91
    p-cymene 11.25
    epichlorohydrin 386.25
    1,1,1-trichloroethane 59.72
    2-aminoethanol 34.35
    morpholine-4-carbaldehyde 206.08
    sulfolane 388.89
    2,2,4-trimethylpentane 1.51
    2-methyltetrahydrofuran 145.34
    n-hexyl acetate 39.92
    isooctane 0.9
    2-(2-butoxyethoxy)ethanol 108.84
    sec-butyl acetate 47.19
    tert-butyl acetate 74.28
    decalin 2.06
    glycerin 56.38
    diglyme 267.4
    acrylic acid 64.04
    isopropyl myristate 21.17
    n-butyric acid 54.42
    acetyl acetate 78.67
    di(2-ethylhexyl) phthalate 20.7
    ethyl propionate 68.64
    nitromethane 405.25
    1,2-diethoxyethane 127.26
    benzonitrile 48.09
    trioctyl phosphate 13.37
    1-bromopropane 46.15
    gamma-valerolactone 224.8
    n-decanol 10.45
    triethyl phosphate 40.16
    4-methyl-2-pentanol 14.43
    propionitrile 62.58
    vinylene carbonate 85.57
    1,1,2-trichlorotrifluoroethane 172.8
    DMS 77.27
    cumene 10.08
    2-octanol 8.31
    2-hexanone 66.53
    octyl acetate 24.73
    limonene 16.64
    1,2-dimethoxyethane 224.14
    ethyl orthosilicate 35.68
    tributyl phosphate 22.29
    diacetone alcohol 91.67
    N,N-dimethylaniline 42.02
    acrylonitrile 104.06
    aniline 35.24
    1,3-propanediol 44.28
    bromobenzene 33.9
    dibromomethane 111.12
    1,1,2,2-tetrachloroethane 213.17
    2-methyl-cyclohexyl acetate 46.77
    tetrabutyl urea 30.81
    diisobutyl methanol 14.37
    2-phenylethanol 34.91
    styrene 18.66
    dioctyl adipate 43.07
    dimethyl sulfate 175.79
    ethyl butyrate 63.52
    methyl lactate 61.8
    butyl lactate 32.68
    diethyl carbonate 48.91
    propanediol butyl ether 44.17
    triethyl orthoformate 51.19
    p-tert-butyltoluene 10.29
    methyl 4-tert-butylbenzoate 61.49
    morpholine 172.98
    tert-butylamine 19.74
    n-dodecanol 8.62
    dimethoxymethane 192.49
    ethylene carbonate 65.16
    cyrene 79.6
    2-ethoxyethyl acetate 72.51
    2-ethylhexyl acetate 38.61
    1,2,4-trichlorobenzene 55.65
    4-methylpyridine 70.23
    dibutyl ether 32.25
    2,6-dimethyl-4-heptanol 14.37
    DEF 112.19
    dimethyl isosorbide 145.01
    tetrachloroethylene 100.86
    eugenol 54.87
    triacetin 91.1
    span 80 47.24
    1,4-butanediol 25.05
    1,1-dichloroethane 88.62
    2-methyl-1-pentanol 28.45
    methyl formate 98.43
    2-methyl-1-butanol 24.54
    n-decane 1.73
    butyronitrile 41.47
    3,7-dimethyl-1-octanol 15.89
    1-chlorooctane 9.64
    1-chlorotetradecane 4.53
    n-nonane 1.36
    undecane 1.38
    tert-butylcyclohexane 1.79
    cyclooctane 0.55
    cyclopentanol 34.98
    tetrahydropyran 98.25
    tert-amyl methyl ether 53.77
    2,5,8-trioxanonane 184.6
    1-hexene 7.23
    2-isopropoxyethanol 76.02
    2,2,2-trifluoroethanol 51.39
    methyl butyrate 81.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction