Perfluorocyclohexylmethanol

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  • Identifiers

    CAS number
    28788-68-3

    Molecular formula
    C7H3F11O

    SMILES
    C(C1(C(C(C(C(C1(F)F)(F)F)(F)F)(F)F)(F)F)F)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 64.41%
    Fishy 22.0%
    Sweet 21.87%
    Woody 21.79%
    Cooling 19.35%
    Savory 14.13%
    Balsamic 14.01%
    Animal 13.56%
    Clean 13.29%
    Camphoreous 13.07%

     

    Flavor
    Bitter 36.34%
    Odorless 36.22%
    Sweet-like 20.94%
    Bland 20.41%
    Bouillon 18.97%
    Bloody 18.48%
    Mild 18.43%
    Nitrile 18.4%
    Rotten 18.37%
    Glue 18.21%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.9

    pKa est.
    4.63 (weak acid)

    Molecular weight
    312.08 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    153°C

    Flash point

    • 60.05 ˚C est.

  • Synonyms

    • (Perfluorocyclohexyl)methanol
    • 28788-68-3
    • Perfluorocyclohexylmethanol
    • Fiflow 145
    • Cyclohexanemethanol, 1,2,2,3,3,4,4,5,5,6,6-undecafluoro-
    • 8V0T4VPX7O
    • (1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexyl)methanol
    • alpha,alpha-Dihydroperfluorocyclohexylcarbinol
    • alpha,alpha-Dihydroperfluorocyclohexane carbinol
    • DTXSID30182964
    • .ALPHA.,.ALPHA.-DIHYDROPERFLUOROCYCLOHEXANE CARBINOL
    • .ALPHA.,.ALPHA.-DIHYDROPERFLUOROCYCLOHEXYLCARBINOL
    • 1,2,2,3,3,4,4,5,5,6,6-UNDECAFLUOROCYCLOHEXANEMETHANOL
    • RefChem:860242
    • DTXCID70105455
    • PERFLUOROCYCLOHEXYLMETHANOL [INCI]
    • 671-708-0
    • (undecafluorocyclohexyl)methanol
    • UNII-8V0T4VPX7O
    • MFCD00126873
    • (Hydroxymethyl)perfluorocyclohexane
    • SCHEMBL864061
    • SCHEMBL9247898
    • BBL101952
    • STL555749
    • AKOS016015608
    • FS-4856
    • NS00018894
    • A819591
    • F010676
    • Q27271049
    • [1,2,2,3,3,4,4,5,5,6,6-undecakis(fluoranyl)cyclohexyl]methanol
    • 28788-68-3

  • Applications

    Perfluorocyclohexylmethanol (CAS 28788-68-3) is primarily used as a fluorinated building block in the synthesis of fluorinated polymers and specialty chemicals; it serves as a reactive intermediate for surface-modification chemistries and as a fluorinated coupling agent to impart water and oil repellency in coatings, inks, and adhesives; it may function as a processing solvent or co-solvent in niche electronics, precision coatings, or cleaning formulations; it can be a precursor for the preparation of fluorinated surfactants or functional additives used to modify surface energy and compatibility in high-performance materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.58
    methanol 93.78
    isopropanol 36.72
    water 5.05
    ethyl acetate 72.51
    n-propanol 40.19
    acetone 120.73
    n-butanol 31.34
    acetonitrile 77.13
    DMF 162.27
    toluene 23.42
    isobutanol 26.63
    1,4-dioxane 81.26
    methyl acetate 84.04
    THF 207.23
    2-butanone 90.39
    n-pentanol 27.23
    sec-butanol 36.23
    n-hexane 4.26
    ethylene glycol 42.35
    NMP 269.2
    cyclohexane 10.11
    DMSO 487.72
    n-butyl acetate 37.76
    n-octanol 21.6
    chloroform 39.27
    n-propyl acetate 39.36
    acetic acid 55.27
    dichloromethane 63.01
    cyclohexanone 76.88
    propylene glycol 31.31
    isopropyl acetate 44.74
    DMAc 213.66
    2-ethoxyethanol 80.06
    isopentanol 27.36
    n-heptane 7.83
    ethyl formate 47.85
    1,2-dichloroethane 57.91
    n-hexanol 30.07
    2-methoxyethanol 126.63
    isobutyl acetate 15.59
    tetrachloromethane 11.78
    n-pentyl acetate 30.56
    transcutol 112.05
    n-heptanol 20.99
    ethylbenzene 14.28
    MIBK 39.7
    2-propoxyethanol 79.75
    tert-butanol 43.03
    MTBE 43.86
    2-butoxyethanol 46.03
    propionic acid 41.7
    o-xylene 22.74
    formic acid 71.26
    diethyl ether 61.65
    m-xylene 16.59
    p-xylene 14.92
    chlorobenzene 14.74
    dimethyl carbonate 60.4
    n-octane 4.02
    formamide 142.55
    cyclopentanone 123.41
    2-pentanone 68.83
    anisole 32.19
    cyclopentyl methyl ether 71.01
    gamma-butyrolactone 137.85
    1-methoxy-2-propanol 85.18
    pyridine 71.68
    3-pentanone 64.42
    furfural 97.01
    n-dodecane 3.13
    diethylene glycol 76.79
    diisopropyl ether 21.51
    tert-amyl alcohol 41.46
    acetylacetone 87.85
    n-hexadecane 3.45
    acetophenone 44.17
    methyl propionate 77.21
    isopentyl acetate 25.63
    trichloroethylene 62.86
    n-nonanol 21.59
    cyclohexanol 32.31
    benzyl alcohol 31.25
    2-ethylhexanol 19.42
    isooctanol 14.91
    dipropyl ether 34.77
    1,2-dichlorobenzene 15.62
    ethyl lactate 30.9
    propylene carbonate 56.82
    n-methylformamide 106.05
    2-pentanol 25.57
    n-pentane 7.31
    1-propoxy-2-propanol 49.88
    1-methoxy-2-propyl acetate 56.12
    2-(2-methoxypropoxy) propanol 49.78
    mesitylene 11.6
    ε-caprolactone 72.94
    p-cymene 14.65
    epichlorohydrin 131.63
    1,1,1-trichloroethane 29.22
    2-aminoethanol 45.53
    morpholine-4-carbaldehyde 147.53
    sulfolane 219.15
    2,2,4-trimethylpentane 3.86
    2-methyltetrahydrofuran 110.47
    n-hexyl acetate 36.08
    isooctane 2.44
    2-(2-butoxyethoxy)ethanol 58.41
    sec-butyl acetate 25.69
    tert-butyl acetate 44.29
    decalin 4.21
    glycerin 51.17
    diglyme 105.21
    acrylic acid 44.81
    isopropyl myristate 17.04
    n-butyric acid 36.36
    acetyl acetate 50.93
    di(2-ethylhexyl) phthalate 16.76
    ethyl propionate 44.74
    nitromethane 188.06
    1,2-diethoxyethane 50.5
    benzonitrile 29.41
    trioctyl phosphate 16.0
    1-bromopropane 34.49
    gamma-valerolactone 121.54
    n-decanol 17.08
    triethyl phosphate 23.09
    4-methyl-2-pentanol 16.55
    propionitrile 48.7
    vinylene carbonate 44.35
    1,1,2-trichlorotrifluoroethane 86.68
    DMS 46.03
    cumene 10.04
    2-octanol 15.5
    2-hexanone 43.96
    octyl acetate 23.51
    limonene 21.96
    1,2-dimethoxyethane 108.35
    ethyl orthosilicate 19.83
    tributyl phosphate 16.15
    diacetone alcohol 59.43
    N,N-dimethylaniline 29.61
    acrylonitrile 65.46
    aniline 30.32
    1,3-propanediol 47.84
    bromobenzene 13.45
    dibromomethane 45.21
    1,1,2,2-tetrachloroethane 54.1
    2-methyl-cyclohexyl acetate 25.07
    tetrabutyl urea 29.0
    diisobutyl methanol 13.03
    2-phenylethanol 32.94
    styrene 14.75
    dioctyl adipate 25.04
    dimethyl sulfate 104.95
    ethyl butyrate 35.37
    methyl lactate 61.65
    butyl lactate 25.42
    diethyl carbonate 25.37
    propanediol butyl ether 34.48
    triethyl orthoformate 25.68
    p-tert-butyltoluene 13.39
    methyl 4-tert-butylbenzoate 39.26
    morpholine 105.75
    tert-butylamine 24.72
    n-dodecanol 13.07
    dimethoxymethane 124.45
    ethylene carbonate 39.59
    cyrene 67.53
    2-ethoxyethyl acetate 46.6
    2-ethylhexyl acetate 22.05
    1,2,4-trichlorobenzene 22.45
    4-methylpyridine 54.21
    dibutyl ether 22.45
    2,6-dimethyl-4-heptanol 13.03
    DEF 88.89
    dimethyl isosorbide 85.06
    tetrachloroethylene 42.25
    eugenol 37.76
    triacetin 43.38
    span 80 32.59
    1,4-butanediol 25.37
    1,1-dichloroethane 33.05
    2-methyl-1-pentanol 24.76
    methyl formate 86.59
    2-methyl-1-butanol 28.26
    n-decane 5.01
    butyronitrile 36.4
    3,7-dimethyl-1-octanol 16.56
    1-chlorooctane 13.14
    1-chlorotetradecane 6.41
    n-nonane 4.58
    undecane 3.94
    tert-butylcyclohexane 2.9
    cyclooctane 5.22
    cyclopentanol 45.02
    tetrahydropyran 67.0
    tert-amyl methyl ether 43.94
    2,5,8-trioxanonane 84.4
    1-hexene 11.37
    2-isopropoxyethanol 50.71
    2,2,2-trifluoroethanol 44.01
    methyl butyrate 47.48

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction