Percoll

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  • Identifiers

    CAS number
    65455-52-9

    Molecular formula
    C186H243N29O26S6

    SMILES
    CCCN(CCC)C1=CC=C(C=C1)C=C(C#N)C(=O)NCC(C)CO.CCCN(CCC)C1=CC2=C(C=C1)C=C(C=C2)C=C(C#N)S(=O)(=O)NCC(C)CO.CCN(CC)C1=CC=C(C=C1)C=C(C#N)C(=O)NCC(C)CO.CCN(CC)C1=CC2=C(C=C1)C=C(C=C2)C=C(C#N)S(=O)(=O)NCC(C)CO.CC(CNC(=O)C(=CC1=CC=C(C=C1)N(C)C)C#N)CO.CC(CNS(=O)(=O)C(=CC1=CC2=C(C=C1)C=C(C=C2)NCCN3CCOCC3)C#N)CO.CC(CNS(=O)(=O)C(=CC1=CC2=C(C=C1)C=C(C=C2)N3CCCCC3)C#N)CO.CC(CNS(=O)(=O)C(=CC1=CC2=C(C=C1)C=C(C=C2)N3CCN(CC3)C)C#N)CO.CC(CNS(=O)(=O)C(=CC1=CC2=C(C=C1)C=C(C=C2)N3CCOCC3)C#N)CO

    Safety labels

  • Odor profile

    Fragrance
    Cooling 36.15%
    Savory 35.36%
    Meaty 31.99%
    Odorless 31.59%
    Mint 27.69%
    Citrus 27.58%
    Grapefruit 27.18%
    Fishy 26.37%
    Animal 25.3%
    Spicy 24.56%

     

    Flavor
    Bitter 62.53%
    Odorless 34.8%
    Bland 26.19%
    Mild 21.94%
    Nitrile 19.85%
    Cedarleaf 19.2%
    Sweet-like 19.14%
    Heather 18.51%
    Oriental 18.47%
    Lovage 18.33%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.58 (neutral)

    Molecular weight
    3493.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1023°C

    Flash point

    • 244.07 ˚C est.

  • Synonyms

    • Percoll
    • 65455-52-9
    • RefChem:860182
    • DTXSID501043474
    • Percoll(R) PLUS
    • 97404-52-9
    • 97404-52-9

  • Applications

    Percoll is used primarily as a density-gradient medium for centrifugation to separate and purify cells, organelles (e.g., mitochondria, nuclei) and other subcellular components; applications span biotechnology and pharmaceutical R&D and biologics production, where it supports purification workflows in biological sample processing; it is also used in clinical laboratories for sample preparation in diagnostic workflows to isolate cells or viruses; and it is commonly employed in teaching laboratories to demonstrate density-gradient separation techniques.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 49.05
    methanol 127.93
    isopropanol 15.1
    water 5.03
    ethyl acetate 26.8
    n-propanol 29.59
    acetone 68.1
    n-butanol 17.77
    acetonitrile 29.32
    DMF 133.38
    toluene 7.87
    isobutanol 17.43
    1,4-dioxane 25.66
    methyl acetate 34.28
    THF 51.13
    2-butanone 41.66
    n-pentanol 26.01
    sec-butanol 14.22
    n-hexane 0.34
    ethylene glycol 42.69
    NMP 150.11
    cyclohexane 0.47
    DMSO 230.43
    n-butyl acetate 17.97
    n-octanol 6.38
    chloroform 76.48
    n-propyl acetate 26.66
    acetic acid 165.93
    dichloromethane 91.14
    cyclohexanone 65.96
    propylene glycol 48.97
    isopropyl acetate 17.06
    DMAc 210.83
    2-ethoxyethanol 71.39
    isopentanol 14.26
    n-heptane 0.28
    ethyl formate 41.73
    1,2-dichloroethane 49.13
    n-hexanol 12.95
    2-methoxyethanol 84.85
    isobutyl acetate 18.96
    tetrachloromethane 8.32
    n-pentyl acetate 16.67
    transcutol 79.89
    n-heptanol 10.24
    ethylbenzene 5.02
    MIBK 18.02
    2-propoxyethanol 46.73
    tert-butanol 12.77
    MTBE 5.55
    2-butoxyethanol 36.91
    propionic acid 59.34
    o-xylene 6.16
    formic acid 147.8
    diethyl ether 5.27
    m-xylene 6.63
    p-xylene 7.38
    chlorobenzene 18.98
    dimethyl carbonate 27.31
    n-octane 0.27
    formamide 151.94
    cyclopentanone 89.42
    2-pentanone 26.13
    anisole 14.23
    cyclopentyl methyl ether 14.51
    gamma-butyrolactone 112.39
    1-methoxy-2-propanol 49.74
    pyridine 40.29
    3-pentanone 21.2
    furfural 108.22
    n-dodecane 0.27
    diethylene glycol 61.01
    diisopropyl ether 1.94
    tert-amyl alcohol 12.66
    acetylacetone 52.68
    n-hexadecane 0.3
    acetophenone 31.62
    methyl propionate 31.13
    isopentyl acetate 17.18
    trichloroethylene 111.12
    n-nonanol 6.71
    cyclohexanol 13.61
    benzyl alcohol 31.77
    2-ethylhexanol 7.43
    isooctanol 9.19
    dipropyl ether 4.24
    1,2-dichlorobenzene 21.28
    ethyl lactate 31.73
    propylene carbonate 65.07
    n-methylformamide 92.93
    2-pentanol 6.93
    n-pentane 0.24
    1-propoxy-2-propanol 25.13
    1-methoxy-2-propyl acetate 27.72
    2-(2-methoxypropoxy) propanol 29.14
    mesitylene 3.92
    ε-caprolactone 54.63
    p-cymene 4.17
    epichlorohydrin 99.96
    1,1,1-trichloroethane 28.17
    2-aminoethanol 60.24
    morpholine-4-carbaldehyde 95.1
    sulfolane 162.36
    2,2,4-trimethylpentane 0.35
    2-methyltetrahydrofuran 23.58
    n-hexyl acetate 15.29
    isooctane 0.23
    2-(2-butoxyethoxy)ethanol 36.42
    sec-butyl acetate 14.94
    tert-butyl acetate 17.12
    decalin 0.58
    glycerin 71.89
    diglyme 63.36
    acrylic acid 73.55
    isopropyl myristate 5.99
    n-butyric acid 53.67
    acetyl acetate 31.92
    di(2-ethylhexyl) phthalate 16.47
    ethyl propionate 19.04
    nitromethane 172.29
    1,2-diethoxyethane 15.99
    benzonitrile 29.45
    trioctyl phosphate 9.9
    1-bromopropane 11.16
    gamma-valerolactone 117.18
    n-decanol 5.05
    triethyl phosphate 12.79
    4-methyl-2-pentanol 5.96
    propionitrile 20.35
    vinylene carbonate 64.06
    1,1,2-trichlorotrifluoroethane 126.4
    DMS 25.43
    cumene 4.35
    2-octanol 5.28
    2-hexanone 24.88
    octyl acetate 9.37
    limonene 4.36
    1,2-dimethoxyethane 52.01
    ethyl orthosilicate 10.91
    tributyl phosphate 11.23
    diacetone alcohol 33.16
    N,N-dimethylaniline 12.92
    acrylonitrile 34.72
    aniline 18.44
    1,3-propanediol 48.14
    bromobenzene 16.57
    dibromomethane 41.44
    1,1,2,2-tetrachloroethane 81.01
    2-methyl-cyclohexyl acetate 18.47
    tetrabutyl urea 15.91
    diisobutyl methanol 3.83
    2-phenylethanol 23.62
    styrene 5.89
    dioctyl adipate 15.61
    dimethyl sulfate 60.97
    ethyl butyrate 16.2
    methyl lactate 44.47
    butyl lactate 25.95
    diethyl carbonate 14.6
    propanediol butyl ether 32.48
    triethyl orthoformate 12.96
    p-tert-butyltoluene 3.65
    methyl 4-tert-butylbenzoate 28.16
    morpholine 38.29
    tert-butylamine 4.23
    n-dodecanol 3.72
    dimethoxymethane 48.24
    ethylene carbonate 48.7
    cyrene 57.21
    2-ethoxyethyl acetate 31.16
    2-ethylhexyl acetate 12.94
    1,2,4-trichlorobenzene 28.27
    4-methylpyridine 32.29
    dibutyl ether 3.89
    2,6-dimethyl-4-heptanol 3.83
    DEF 39.88
    dimethyl isosorbide 48.91
    tetrachloroethylene 50.9
    eugenol 36.21
    triacetin 33.72
    span 80 25.5
    1,4-butanediol 42.34
    1,1-dichloroethane 30.77
    2-methyl-1-pentanol 20.03
    methyl formate 79.25
    2-methyl-1-butanol 15.42
    n-decane 0.4
    butyronitrile 19.22
    3,7-dimethyl-1-octanol 6.45
    1-chlorooctane 2.61
    1-chlorotetradecane 1.2
    n-nonane 0.33
    undecane 0.32
    tert-butylcyclohexane 0.55
    cyclooctane 0.21
    cyclopentanol 21.59
    tetrahydropyran 14.01
    tert-amyl methyl ether 6.16
    2,5,8-trioxanonane 46.21
    1-hexene 2.17
    2-isopropoxyethanol 42.85
    2,2,2-trifluoroethanol 74.83
    methyl butyrate 30.22

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction