Oleic monoisopropanolamide

Overview IFRA Request a quote

  • Identifiers

    CAS number
    111-05-7

    Molecular formula
    C21H41NO2

    SMILES
    CCCCCCCC/C=C\CCCCCCCC(=O)NCC(C)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fatty 41.0%
    Meaty 39.56%
    Waxy 37.74%
    Savory 34.87%
    Oily 31.78%
    Citrus 29.9%
    Odorless 26.12%
    Fishy 25.79%
    Fresh 25.49%
    Herbal 25.23%

     

    Flavor
    Fatty 29.23%
    Faint 28.96%
    Mild 28.87%
    Bland 28.78%
    Waxy 25.95%
    Odorless 25.34%
    Slightly waxy 22.54%
    Delicate 21.59%
    Herbal 21.38%
    Bay oil 21.16%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.8

    pKa est.
    7.85 (neutral)

    Molecular weight
    339.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    416°C

    Flash point

    • 205.4 ˚C est.

  • Synonyms

    • N-(2-Hydroxypropyl)oleamide
    • 111-05-7
    • Oleic monoisopropanolamide
    • Oleamide MIPA
    • Oleic acid isopropanolamide
    • 9-Octadecenamide, N-(2-hydroxypropyl)-, (Z)-
    • 9-Octadecenamide, N-(2-hydroxypropyl)-, (9Z)-
    • MACKAMIDE OP
    • 63Y91GM18S
    • OLEOYL ISOPROPANOLAMIDE
    • OLEYLMONOISOPROPANOLAMIDE
    • DTXSID90883304
    • OLEAMIDE, N-(2-HYDROXYPROPYL)-
    • RefChem:856525
    • OLEAMIDE MIPA [INCI]
    • DTXCID001022843
    • (9Z)-N-(2-Hydroxypropyl)-9-octadecenamide
    • 203-828-2
    • (Z)-N-(2-hydroxypropyl)octadec-9-enamide
    • Oleic acid monoisopropanolamide
    • UNII-63Y91GM18S
    • EINECS 203-828-2
    • N-(2-Hydroxypropyl)-9-octadecenamide
    • (9Z)-N-(2-hydroxypropyl)octadec-9-enamide
    • EC 203-828-2
    • SCHEMBL4096417
    • UDZAXLGLNUMCRX-KHPPLWFESA-N
    • Monoisopropanolamine oleic acid amide
    • AT24304
    • 9-Octadecenamide, N-(2-hydroxypropyl)-
    • NS00006863
    • Q27263662
    • 111-05-7

  • Applications

    Oleic monoisopropanolamide (CAS 111-05-7) is a fatty amide used primarily as a nonionic surfactant and emulsifier in a range of formulations. In cosmetics and personal care, it acts as a mild surfactant, emulsifier, and conditioning agent; in household cleaning products, it serves as a surfactant and wetting agent to improve dispersion and foaming; in industrial manufacturing, it is used as a surface-active agent and emulsifier for latex, coatings, and adhesive/ink systems; in polymers/plastics, it can function as a processing aid and emulsifier to improve dispersion and compatibility of components; in coatings and inks, it serves as a dispersant and stabilizer to stabilize formulations and improve film formation.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 34.56
    methanol 52.98
    isopropanol 29.44
    water 0.04
    ethyl acetate 59.62
    n-propanol 33.06
    acetone 58.16
    n-butanol 42.14
    acetonitrile 13.99
    DMF 92.7
    toluene 21.85
    isobutanol 31.33
    1,4-dioxane 90.03
    methyl acetate 39.51
    THF 264.66
    2-butanone 68.59
    n-pentanol 41.74
    sec-butanol 38.1
    n-hexane 6.33
    ethylene glycol 2.71
    NMP 184.25
    cyclohexane 22.35
    DMSO 205.36
    n-butyl acetate 83.22
    n-octanol 39.26
    chloroform 153.65
    n-propyl acetate 100.95
    acetic acid 47.08
    dichloromethane 140.46
    cyclohexanone 216.25
    propylene glycol 10.5
    isopropyl acetate 71.73
    DMAc 246.04
    2-ethoxyethanol 90.03
    isopentanol 57.85
    n-heptane 6.61
    ethyl formate 35.59
    1,2-dichloroethane 102.59
    n-hexanol 36.71
    2-methoxyethanol 81.95
    isobutyl acetate 75.12
    tetrachloromethane 33.86
    n-pentyl acetate 118.86
    transcutol 488.2
    n-heptanol 37.7
    ethylbenzene 23.31
    MIBK 88.37
    2-propoxyethanol 89.41
    tert-butanol 59.97
    MTBE 73.7
    2-butoxyethanol 104.03
    propionic acid 34.24
    o-xylene 26.8
    formic acid 12.79
    diethyl ether 42.14
    m-xylene 21.95
    p-xylene 32.28
    chlorobenzene 38.54
    dimethyl carbonate 18.0
    n-octane 3.82
    formamide 18.68
    cyclopentanone 182.2
    2-pentanone 79.96
    anisole 54.02
    cyclopentyl methyl ether 110.9
    gamma-butyrolactone 150.0
    1-methoxy-2-propanol 86.32
    pyridine 70.53
    3-pentanone 60.24
    furfural 122.2
    n-dodecane 2.77
    diethylene glycol 39.0
    diisopropyl ether 21.76
    tert-amyl alcohol 66.14
    acetylacetone 100.91
    n-hexadecane 3.27
    acetophenone 77.85
    methyl propionate 44.85
    isopentyl acetate 96.92
    trichloroethylene 171.9
    n-nonanol 39.88
    cyclohexanol 77.04
    benzyl alcohol 42.04
    2-ethylhexanol 37.22
    isooctanol 39.81
    dipropyl ether 53.92
    1,2-dichlorobenzene 50.76
    ethyl lactate 47.17
    propylene carbonate 96.34
    n-methylformamide 28.24
    2-pentanol 33.53
    n-pentane 3.93
    1-propoxy-2-propanol 88.65
    1-methoxy-2-propyl acetate 97.02
    2-(2-methoxypropoxy) propanol 96.62
    mesitylene 19.0
    ε-caprolactone 181.48
    p-cymene 20.93
    epichlorohydrin 169.73
    1,1,1-trichloroethane 102.15
    2-aminoethanol 13.1
    morpholine-4-carbaldehyde 151.82
    sulfolane 285.25
    2,2,4-trimethylpentane 7.1
    2-methyltetrahydrofuran 159.65
    n-hexyl acetate 118.62
    isooctane 3.68
    2-(2-butoxyethoxy)ethanol 140.07
    sec-butyl acetate 78.68
    tert-butyl acetate 105.92
    decalin 12.02
    glycerin 19.95
    diglyme 297.92
    acrylic acid 22.76
    isopropyl myristate 37.52
    n-butyric acid 90.13
    acetyl acetate 42.95
    di(2-ethylhexyl) phthalate 40.42
    ethyl propionate 69.04
    nitromethane 73.28
    1,2-diethoxyethane 127.63
    benzonitrile 42.51
    trioctyl phosphate 28.87
    1-bromopropane 55.65
    gamma-valerolactone 252.69
    n-decanol 24.72
    triethyl phosphate 50.22
    4-methyl-2-pentanol 31.96
    propionitrile 21.84
    vinylene carbonate 67.48
    1,1,2-trichlorotrifluoroethane 147.6
    DMS 48.73
    cumene 21.25
    2-octanol 30.2
    2-hexanone 99.31
    octyl acetate 47.06
    limonene 35.56
    1,2-dimethoxyethane 193.73
    ethyl orthosilicate 55.92
    tributyl phosphate 37.62
    diacetone alcohol 120.63
    N,N-dimethylaniline 49.26
    acrylonitrile 20.44
    aniline 29.88
    1,3-propanediol 31.64
    bromobenzene 41.31
    dibromomethane 90.54
    1,1,2,2-tetrachloroethane 190.6
    2-methyl-cyclohexyl acetate 84.79
    tetrabutyl urea 58.99
    diisobutyl methanol 28.83
    2-phenylethanol 41.45
    styrene 25.02
    dioctyl adipate 68.26
    dimethyl sulfate 48.26
    ethyl butyrate 80.16
    methyl lactate 32.9
    butyl lactate 94.35
    diethyl carbonate 44.0
    propanediol butyl ether 89.91
    triethyl orthoformate 75.66
    p-tert-butyltoluene 20.64
    methyl 4-tert-butylbenzoate 97.77
    morpholine 137.84
    tert-butylamine 35.34
    n-dodecanol 16.83
    dimethoxymethane 67.05
    ethylene carbonate 63.51
    cyrene 99.89
    2-ethoxyethyl acetate 135.6
    2-ethylhexyl acetate 77.19
    1,2,4-trichlorobenzene 64.4
    4-methylpyridine 71.88
    dibutyl ether 70.99
    2,6-dimethyl-4-heptanol 28.83
    DEF 110.98
    dimethyl isosorbide 177.7
    tetrachloroethylene 124.81
    eugenol 84.99
    triacetin 126.48
    span 80 91.67
    1,4-butanediol 14.58
    1,1-dichloroethane 76.65
    2-methyl-1-pentanol 55.34
    methyl formate 19.72
    2-methyl-1-butanol 50.34
    n-decane 6.29
    butyronitrile 34.83
    3,7-dimethyl-1-octanol 42.02
    1-chlorooctane 30.52
    1-chlorotetradecane 9.33
    n-nonane 5.78
    undecane 3.87
    tert-butylcyclohexane 9.34
    cyclooctane 5.71
    cyclopentanol 62.41
    tetrahydropyran 142.7
    tert-amyl methyl ether 69.2
    2,5,8-trioxanonane 172.36
    1-hexene 21.02
    2-isopropoxyethanol 79.0
    2,2,2-trifluoroethanol 18.53
    methyl butyrate 113.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction