Octamethyltrisiloxane

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  • Identifiers

    CAS number
    107-51-7

    Molecular formula
    C8H24O2Si3

    SMILES
    C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Mint 32.07%
    Odorless 31.1%
    Green 27.76%
    Alcoholic 25.22%
    Camphoreous 24.56%
    Fresh 24.44%
    Ethereal 23.16%
    Fishy 22.71%
    Cooling 22.55%
    Fermented 22.03%

     

    Flavor
    Green 31.15%
    Pungent 28.86%
    Earthy 23.26%
    Mild 20.88%
    Blackberry 19.92%
    Rose acetate 19.9%
    Catty 19.84%
    Black currant 19.75%
    Cat-urine 19.51%
    Camphor 19.42%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.49 (neutral)

    Molecular weight
    236.53 g/mol

    Flash point

    • 44.35 ˚C est.

  • Synonyms

    • OCTAMETHYLTRISILOXANE
    • 107-51-7
    • Trisiloxane, octamethyl-
    • 1,1,1,3,3,5,5,5-Octamethyltrisiloxane
    • dimethyl-bis(trimethylsilyloxy)silane
    • Pentamethyl(trimethylsilyloxy)disiloxane
    • Dimethylbis(trimethylsiloxy)silane
    • 9G1ZW13R0G
    • DTXSID9040710
    • Pentamethyl(trimethylsiloxy)disiloxane
    • CHEBI:9147
    • DTXCID7020710
    • RefChem:1093790
    • 203-497-4
    • Dimethicone 350
    • MFCD00008264
    • Silicone oil PMX-200
    • S12475
    • Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-
    • MFCD00084411
    • MFCD00148360
    • 28349-86-2
    • CCRIS 3198
    • EINECS 203-497-4
    • UNII-9G1ZW13R0G
    • C8H24O2Si3
    • Dimeticone CRS
    • Ctamethyltrisiloxane
    • octamethyl-trisiloxane
    • Simethicone Impurity 6
    • dimethicone macromolecule
    • EC 203-497-4
    • Octamethyltrisiloxane, 98%
    • SCHEMBL23459
    • DMS-T01
    • DMS-T02
    • DMS-T11
    • DMS-T12
    • DMS-T15
    • DMS-T25
    • DMS-T31
    • TRISILOXANE, OCTAMETHYL
    • Dow Corning High-Vacuum Grease
    • SCHEMBL1181924
    • CHEMBL2142985
    • CHEBI:31498
    • CXQXSVUQTKDNFP-UHFFFAOYSA-
    • OCTAMETHYLTRISILOXANE [MI]
    • dimethylbis(trimethylsiloxy)siliane
    • 2,2,4,4,6,6-hexamethyl-3,5-dioxa-2,4,6-trisilaheptane
    • Dimethylbis(trimethylsilyloxy)silane
    • [(CH3)3SiO]2Si(CH3)2
    • Tox21_301002
    • CO9816
    • MFCD00134211
    • MFCD00165850
    • Silane, dimethylbis(trimethylsiloxy)-
    • AKOS015840180
    • FS-4459
    • FS34581
    • MSK001891-100M
    • Dimethylsiliconeoil;Dimethylpolysiloxane;
    • NCGC00164100-01
    • NCGC00164100-02
    • NCGC00254904-01
    • CAS-107-51-7
    • DB-040764
    • NS00041459
    • O0257
    • O9816
    • C07261
    • D91850
    • SBI-0654020.0001
    • A801717
    • Polydimethysiloxanetrimethylsiloxy terminated cSt20
    • Q2013799
    • BRD-K73201113-001-01-3
    • Octamethyltrisiloxane Solution in Methanol, 100ug/mL
    • Polydimethylsiloxane,trimethylsiloxy terminated cSt 50
    • Polydimethylsiloxane, trimethylsiloxy terminated 500cSt
    • Polydimethylsiloxane, trimethylsiloxy terminated cSt 10
    • Polydimethylsiloxanes, trimethylsiloxy terminated cSt 1.0
    • Polydimethylsiloxanes, trimethylsiloxy terminated cSt 2.0
    • Polydimethylsiloxane, trimethylsiloxy terminated 1,000cSt
    • InChI=1/C8H24O2Si3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h1-8H3
    • 107-51-7

  • Applications

    Octamethyltrisiloxane (CAS 107-51-7) is used primarily as a reactive intermediate and processing aid in organosilicon chemistry. It serves as a precursor for the synthesis of silicone oligomers and resins, enabling the formation of higher‑molecular‑weight siloxanes. It can function as a volatile solvent or diluent in coatings, inks, and adhesive formulations, aiding flow and evaporation characteristics. In cosmetics and perfumery, it may be employed as a volatile silicone solvent or carrier for fragrance oils and formulation ingredients, within regulatory limits. It is also considered as a component in cleaning formulations and industrial degreasers as a silicone solvent, and as a starting material for functionalized siloxane additives and specialty polymers.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 423.39
    methanol 533.47
    isopropanol 291.86
    water 13.35
    ethyl acetate 269.61
    n-propanol 354.66
    acetone 365.58
    n-butanol 301.46
    acetonitrile 198.91
    DMF 485.45
    toluene 237.2
    isobutanol 216.44
    1,4-dioxane 544.4
    methyl acetate 239.1
    THF 1336.07
    2-butanone 272.18
    n-pentanol 226.49
    sec-butanol 260.97
    n-hexane 165.58
    ethylene glycol 134.15
    NMP 643.25
    cyclohexane 306.23
    DMSO 453.28
    n-butyl acetate 258.54
    n-octanol 241.58
    chloroform 502.29
    n-propyl acetate 196.95
    acetic acid 282.47
    dichloromethane 424.47
    cyclohexanone 551.46
    propylene glycol 211.13
    isopropyl acetate 197.67
    DMAc 344.62
    2-ethoxyethanol 277.84
    isopentanol 188.68
    n-heptane 188.99
    ethyl formate 213.08
    1,2-dichloroethane 264.58
    n-hexanol 375.45
    2-methoxyethanol 519.11
    isobutyl acetate 143.37
    tetrachloromethane 143.06
    n-pentyl acetate 244.58
    transcutol 443.64
    n-heptanol 231.48
    ethylbenzene 121.13
    MIBK 189.35
    2-propoxyethanol 510.34
    tert-butanol 271.42
    MTBE 189.72
    2-butoxyethanol 276.59
    propionic acid 252.52
    o-xylene 143.23
    formic acid 155.34
    diethyl ether 366.81
    m-xylene 169.85
    p-xylene 141.12
    chlorobenzene 210.67
    dimethyl carbonate 140.08
    n-octane 83.2
    formamide 191.1
    cyclopentanone 684.9
    2-pentanone 294.8
    anisole 192.06
    cyclopentyl methyl ether 538.42
    gamma-butyrolactone 653.06
    1-methoxy-2-propanol 460.96
    pyridine 362.19
    3-pentanone 223.17
    furfural 468.35
    n-dodecane 53.17
    diethylene glycol 336.0
    diisopropyl ether 135.92
    tert-amyl alcohol 212.35
    acetylacetone 284.86
    n-hexadecane 58.04
    acetophenone 184.15
    methyl propionate 250.31
    isopentyl acetate 199.26
    trichloroethylene 347.75
    n-nonanol 213.61
    cyclohexanol 361.83
    benzyl alcohol 168.12
    2-ethylhexanol 216.93
    isooctanol 164.18
    dipropyl ether 322.38
    1,2-dichlorobenzene 176.94
    ethyl lactate 131.66
    propylene carbonate 372.9
    n-methylformamide 325.84
    2-pentanol 224.43
    n-pentane 167.97
    1-propoxy-2-propanol 371.46
    1-methoxy-2-propyl acetate 280.23
    2-(2-methoxypropoxy) propanol 176.9
    mesitylene 121.68
    ε-caprolactone 445.77
    p-cymene 114.87
    epichlorohydrin 425.37
    1,1,1-trichloroethane 238.17
    2-aminoethanol 247.55
    morpholine-4-carbaldehyde 504.93
    sulfolane 639.73
    2,2,4-trimethylpentane 52.77
    2-methyltetrahydrofuran 601.92
    n-hexyl acetate 306.68
    isooctane 47.73
    2-(2-butoxyethoxy)ethanol 271.63
    sec-butyl acetate 137.68
    tert-butyl acetate 202.56
    decalin 94.21
    glycerin 258.57
    diglyme 390.26
    acrylic acid 201.71
    isopropyl myristate 144.93
    n-butyric acid 327.52
    acetyl acetate 193.02
    di(2-ethylhexyl) phthalate 121.19
    ethyl propionate 185.25
    nitromethane 334.26
    1,2-diethoxyethane 245.55
    benzonitrile 191.61
    trioctyl phosphate 113.43
    1-bromopropane 260.52
    gamma-valerolactone 654.16
    n-decanol 160.93
    triethyl phosphate 111.94
    4-methyl-2-pentanol 131.15
    propionitrile 199.19
    vinylene carbonate 321.72
    1,1,2-trichlorotrifluoroethane 317.33
    DMS 185.26
    cumene 92.1
    2-octanol 188.86
    2-hexanone 206.8
    octyl acetate 180.85
    limonene 184.36
    1,2-dimethoxyethane 399.08
    ethyl orthosilicate 117.38
    tributyl phosphate 114.54
    diacetone alcohol 221.98
    N,N-dimethylaniline 163.62
    acrylonitrile 198.16
    aniline 237.1
    1,3-propanediol 294.45
    bromobenzene 203.28
    dibromomethane 360.33
    1,1,2,2-tetrachloroethane 320.38
    2-methyl-cyclohexyl acetate 204.21
    tetrabutyl urea 164.91
    diisobutyl methanol 130.49
    2-phenylethanol 242.07
    styrene 138.63
    dioctyl adipate 165.46
    dimethyl sulfate 180.84
    ethyl butyrate 202.0
    methyl lactate 203.78
    butyl lactate 201.06
    diethyl carbonate 129.09
    propanediol butyl ether 271.78
    triethyl orthoformate 169.51
    p-tert-butyltoluene 126.29
    methyl 4-tert-butylbenzoate 213.59
    morpholine 608.23
    tert-butylamine 224.7
    n-dodecanol 126.51
    dimethoxymethane 478.59
    ethylene carbonate 287.24
    cyrene 215.77
    2-ethoxyethyl acetate 233.79
    2-ethylhexyl acetate 187.12
    1,2,4-trichlorobenzene 203.7
    4-methylpyridine 338.6
    dibutyl ether 218.04
    2,6-dimethyl-4-heptanol 130.49
    DEF 290.63
    dimethyl isosorbide 373.17
    tetrachloroethylene 236.22
    eugenol 209.51
    triacetin 218.47
    span 80 253.37
    1,4-butanediol 131.54
    1,1-dichloroethane 250.98
    2-methyl-1-pentanol 146.07
    methyl formate 249.93
    2-methyl-1-butanol 188.48
    n-decane 93.51
    butyronitrile 219.12
    3,7-dimethyl-1-octanol 179.22
    1-chlorooctane 180.1
    1-chlorotetradecane 81.14
    n-nonane 98.84
    undecane 67.01
    tert-butylcyclohexane 82.65
    cyclooctane 143.13
    cyclopentanol 455.5
    tetrahydropyran 644.97
    tert-amyl methyl ether 178.19
    2,5,8-trioxanonane 297.31
    1-hexene 237.6
    2-isopropoxyethanol 188.01
    2,2,2-trifluoroethanol 118.47
    methyl butyrate 212.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction