Octafluorocyclobutane

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  • Identifiers

    CAS number
    115-25-3

    Molecular formula
    C4F8

    SMILES
    C1(C(C(C1(F)F)(F)F)(F)F)(F)F

    Safety labels

    Compressed Gas
    Compressed Gas

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 65.98%
    Fishy 22.14%
    Woody 18.98%
    Sweet 18.97%
    Cooling 16.96%
    Savory 13.54%
    Burnt 12.85%
    Animal 12.82%
    Clean 12.36%
    Balsamic 12.26%

     

    Flavor
    Bitter 33.18%
    Odorless 32.64%
    Sweet-like 19.69%
    Bland 18.79%
    Bouillon 18.45%
    Bloody 18.18%
    Rotten 18.17%
    Nitrile 18.1%
    Glue 17.87%
    Scallion 17.85%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    4.97 (weak acid)

    Molecular weight
    200.03 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    -8°C

    Melting point expt.

    • -41.4 °C

    Flash point

    • -34.34 ˚C est.

    Solubility expt.

    • 0.0236 mg/mL at 25 °C

  • Synonyms

    • Octafluorocyclobutane
    • PERFLUOROCYCLOBUTANE
    • 115-25-3
    • Cyclooctafluorobutane
    • Freon C-318
    • Propellant C318
    • Freon C 318
    • freon c318
    • FC-C 318
    • R-C 318
    • V9P1D0A21K
    • E946
    • DTXSID9041811
    • CHEBI:31007
    • RefChem:167720
    • FKWC 318
    • FLON C 318
    • FRON C 318
    • DTXCID7021811
    • FC 318
    • C 318
    • R 318
    • 204-075-2
    • 1,1,2,2,3,3,4,4-Octafluorocyclobutane
    • Halocarbon C-138
    • Cyclobutane, octafluoro-
    • Freon 318
    • Cyclobutane, 1,1,2,2,3,3,4,4-octafluoro-
    • MFCD00040334
    • EINECS 204-075-2
    • UN1976
    • UNII-V9P1D0A21K
    • octafluoro-cyclobutane
    • Propellant C 318
    • Fluorocarbon C-318
    • Cyclobutane,1,1,2,2,3,3,4,4-octafluoro-
    • SCHEMBL24521
    • CHEMBL444147
    • OCTAFLUOROCYCLOBUTANE [MI]
    • Perfluorocyclobutane (PFC C-318)
    • R C318
    • SBB092541
    • AKOS015853421
    • UN 1976
    • C318
    • E 946
    • E-946
    • NS00009691
    • O0204
    • 1,1,2,2,3,3,4,4-Octafluoro-Cyclobutane
    • 1,1,2,2,3,3,4,4-Octafluorocyclobutane #
    • Octafluorocyclobutane, or Refrigerant gas R C318
    • Q413079
    • Octafluorocyclobutane, or Refrigerant gas R C318 [UN1976] [Nonflammable gas]
    • 25510-99-0
    • 115-25-3

  • Applications

    Octafluorocyclobutane (CAS 115-25-3) is primarily used as a fluorinated process gas in electronics manufacturing, where it participates in plasma etching and in chemical vapor deposition to form fluorocarbon films that protect surfaces and control etch profiles; it also serves as a coating precursor for fluorinated, wear- and chemical-resistant films on metals, plastics, and optical components; in polymer/plastics processing, it is evaluated for surface fluorination and modification to lower surface energy and improve chemical resistance; overall, its applications are driven by specific process conditions and regulatory requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 40.74
    methanol 77.72
    isopropanol 31.09
    water 16.23
    ethyl acetate 21.29
    n-propanol 31.63
    acetone 51.25
    n-butanol 23.54
    acetonitrile 45.35
    DMF 190.48
    toluene 6.43
    isobutanol 22.77
    1,4-dioxane 31.12
    methyl acetate 29.74
    THF 73.6
    2-butanone 39.4
    n-pentanol 17.83
    sec-butanol 26.46
    n-hexane 4.04
    ethylene glycol 44.75
    NMP 200.94
    cyclohexane 6.11
    DMSO 422.66
    n-butyl acetate 16.61
    n-octanol 11.33
    chloroform 19.03
    n-propyl acetate 17.28
    acetic acid 36.01
    dichloromethane 24.89
    cyclohexanone 35.06
    propylene glycol 38.93
    isopropyl acetate 15.46
    DMAc 186.59
    2-ethoxyethanol 51.07
    isopentanol 19.29
    n-heptane 6.52
    ethyl formate 24.25
    1,2-dichloroethane 21.9
    n-hexanol 16.74
    2-methoxyethanol 82.53
    isobutyl acetate 8.62
    tetrachloromethane 5.38
    n-pentyl acetate 9.95
    transcutol 67.59
    n-heptanol 9.65
    ethylbenzene 5.8
    MIBK 18.22
    2-propoxyethanol 47.68
    tert-butanol 31.25
    MTBE 19.78
    2-butoxyethanol 23.2
    propionic acid 31.49
    o-xylene 9.15
    formic acid 54.47
    diethyl ether 23.74
    m-xylene 6.51
    p-xylene 6.44
    chlorobenzene 4.51
    dimethyl carbonate 24.59
    n-octane 2.57
    formamide 103.93
    cyclopentanone 54.09
    2-pentanone 28.46
    anisole 12.45
    cyclopentyl methyl ether 31.11
    gamma-butyrolactone 63.36
    1-methoxy-2-propanol 65.75
    pyridine 27.55
    3-pentanone 29.12
    furfural 46.51
    n-dodecane 1.88
    diethylene glycol 56.51
    diisopropyl ether 9.14
    tert-amyl alcohol 27.44
    acetylacetone 30.2
    n-hexadecane 2.0
    acetophenone 20.01
    methyl propionate 32.84
    isopentyl acetate 12.36
    trichloroethylene 21.99
    n-nonanol 11.19
    cyclohexanol 23.25
    benzyl alcohol 16.46
    2-ethylhexanol 11.82
    isooctanol 7.69
    dipropyl ether 21.76
    1,2-dichlorobenzene 5.19
    ethyl lactate 25.71
    propylene carbonate 28.62
    n-methylformamide 90.79
    2-pentanol 18.82
    n-pentane 5.98
    1-propoxy-2-propanol 36.65
    1-methoxy-2-propyl acetate 26.89
    2-(2-methoxypropoxy) propanol 33.92
    mesitylene 5.4
    ε-caprolactone 33.94
    p-cymene 7.99
    epichlorohydrin 44.1
    1,1,1-trichloroethane 10.79
    2-aminoethanol 48.51
    morpholine-4-carbaldehyde 102.85
    sulfolane 125.14
    2,2,4-trimethylpentane 2.92
    2-methyltetrahydrofuran 37.34
    n-hexyl acetate 12.74
    isooctane 2.01
    2-(2-butoxyethoxy)ethanol 35.02
    sec-butyl acetate 11.32
    tert-butyl acetate 16.61
    decalin 2.85
    glycerin 58.68
    diglyme 56.15
    acrylic acid 34.71
    isopropyl myristate 7.53
    n-butyric acid 24.88
    acetyl acetate 13.5
    di(2-ethylhexyl) phthalate 7.95
    ethyl propionate 19.79
    nitromethane 81.82
    1,2-diethoxyethane 20.23
    benzonitrile 13.02
    trioctyl phosphate 7.59
    1-bromopropane 15.59
    gamma-valerolactone 63.72
    n-decanol 9.13
    triethyl phosphate 15.7
    4-methyl-2-pentanol 11.7
    propionitrile 31.27
    vinylene carbonate 22.17
    1,1,2-trichlorotrifluoroethane 52.46
    DMS 16.19
    cumene 5.36
    2-octanol 7.05
    2-hexanone 19.4
    octyl acetate 9.36
    limonene 12.29
    1,2-dimethoxyethane 62.15
    ethyl orthosilicate 13.96
    tributyl phosphate 9.44
    diacetone alcohol 32.47
    N,N-dimethylaniline 18.67
    acrylonitrile 40.36
    aniline 13.78
    1,3-propanediol 39.37
    bromobenzene 3.51
    dibromomethane 19.02
    1,1,2,2-tetrachloroethane 24.49
    2-methyl-cyclohexyl acetate 15.66
    tetrabutyl urea 18.43
    diisobutyl methanol 10.09
    2-phenylethanol 15.27
    styrene 5.52
    dioctyl adipate 12.76
    dimethyl sulfate 47.96
    ethyl butyrate 19.79
    methyl lactate 41.96
    butyl lactate 16.9
    diethyl carbonate 14.46
    propanediol butyl ether 25.87
    triethyl orthoformate 17.09
    p-tert-butyltoluene 7.77
    methyl 4-tert-butylbenzoate 20.26
    morpholine 52.26
    tert-butylamine 23.21
    n-dodecanol 7.44
    dimethoxymethane 68.84
    ethylene carbonate 19.85
    cyrene 48.21
    2-ethoxyethyl acetate 14.06
    2-ethylhexyl acetate 10.7
    1,2,4-trichlorobenzene 7.78
    4-methylpyridine 21.81
    dibutyl ether 10.91
    2,6-dimethyl-4-heptanol 10.09
    DEF 55.44
    dimethyl isosorbide 52.48
    tetrachloroethylene 16.23
    eugenol 21.28
    triacetin 20.71
    span 80 22.9
    1,4-butanediol 23.43
    1,1-dichloroethane 14.21
    2-methyl-1-pentanol 14.11
    methyl formate 53.64
    2-methyl-1-butanol 20.03
    n-decane 2.89
    butyronitrile 23.21
    3,7-dimethyl-1-octanol 10.13
    1-chlorooctane 5.74
    1-chlorotetradecane 3.29
    n-nonane 2.79
    undecane 2.27
    tert-butylcyclohexane 2.35
    cyclooctane 3.25
    cyclopentanol 32.15
    tetrahydropyran 25.24
    tert-amyl methyl ether 21.47
    2,5,8-trioxanonane 48.04
    1-hexene 7.53
    2-isopropoxyethanol 30.71
    2,2,2-trifluoroethanol 31.1
    methyl butyrate 24.08

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction