Nitrogen tetroxide

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  • Identifiers

    CAS number
    10544-72-6

    Molecular formula
    N2O4

    SMILES
    [N+](=O)([N+](=O)[O-])[O-]

    Safety labels

    Oxidizer
    Oxidizer

    Compressed Gas
    Compressed Gas

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 64.82%
    Caramellic 33.56%
    Sweet 32.15%
    Burnt 25.85%
    Sour 25.24%
    Buttery 23.85%
    Sharp 20.66%
    Fatty 18.84%
    Creamy 18.35%
    Ethereal 16.68%

     

    Flavor
    Odorless 58.34%
    Very mild 27.98%
    Bitter 25.3%
    Nutty 22.95%
    Mild 20.92%
    Caramellic 20.83%
    Yeast 20.13%
    Sour 19.8%
    Bread crust 19.38%
    Bland 19.3%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    5.99 (weak acid)

    Molecular weight
    92.011 g/mol

    Melting point expt.

    • 11.8 °F (USCG, 1999)
    • -9.3 °C

    Boiling point

    • 70.1 °F at 760 mmHg (USCG, 1999)
    • 21.15 °C

    Flash point

    • 83.02 ˚C est.

    Solubility expt.

    • Reacts with water

  • Synonyms

    • Dinitrogen tetroxide
    • NITROGEN TETROXIDE
    • Dinitrogen tetraoxide
    • 10544-72-6
    • Nitrogen oxide (N2O4)
    • Di-nitrogen dioxide
    • Nitrogen dioxide, di-
    • HSDB 1067
    • UNII-M9APC3P75A
    • EINECS 234-126-4
    • UN1067
    • bis(dioxidonitrogen)(N--N)
    • M9APC3P75A
    • CHEBI:29803
    • DINITROGEN TETROXIDE [MI]
    • NITROGEN TETROXIDE [HSDB]
    • DTXSID00893116
    • EC 234-126-4
    • Nitrogen tetraoxide
    • NITROGEN TETROXIDE, (LIQUID)
    • NITROGEN TETROXIDE, [LIQUID]
    • Nitrogen oxide NO2
    • NITROGEN PEROXIDE (DINITROGEN TETROXIDE)
    • NITROGEN PEROXIDE {DINITROGEN TETROXIDE}
    • RCRA waste no. P078
    • N2O4
    • Peroxyde d'azote
    • Tetroxyde d'azote
    • Nitrogen tetroxide 10% by volume
    • Distickstofftetroxid
    • tetraoxyde de diazote
    • Nitrogen dioxide, di
    • Nitrogen peroxide liquid
    • tetraoxido de dinitrogeno
    • OXIDES OF NITROGEN
    • O2NNO2
    • Tetroxyde d'azote (French)
    • RED OXIDE OF NITROGEN
    • WFPZPJSADLPSON-UHFFFAOYSA-N
    • [N(NO2)O2]
    • DTXCID501323062
    • Dinitrogen tetroxide [UN1067] [Poison gas]
    • Q382984
    • NITROGEN DIOXIDE/DINITROGEN TETROXIDE MIXTURE

  • Applications

    Nitrogen tetroxide (CAS 10544-72-6) is a strong oxidizer widely used as the oxidizer component in bipropellant rocket propulsion, pairing with fuels such as hydrazine derivatives in space launch and defense applications. In industrial manufacturing, it serves as a high-level oxidizing agent in controlled chemical syntheses and processing steps, including NOx generation in research and development workflows. In research contexts, it is used as a source of nitrogen oxides (NOx) for laboratory studies, process development, and calibration of NOx measurement equipment, and it can act as an intermediate toward the production of other nitrogen oxide species in specialized pipelines and test environments to simulate oxidizer-rich conditions. All applications are conducted under strict safety protocols and regulatory controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 19.48
    methanol 40.6
    isopropanol 10.87
    water 23.74
    ethyl acetate 5.78
    n-propanol 11.57
    acetone 20.68
    n-butanol 7.87
    acetonitrile 13.87
    DMF 128.69
    toluene 1.22
    isobutanol 6.52
    1,4-dioxane 14.38
    methyl acetate 12.05
    THF 18.86
    2-butanone 13.88
    n-pentanol 5.47
    sec-butanol 8.77
    n-hexane 0.75
    ethylene glycol 30.0
    NMP 110.18
    cyclohexane 2.22
    DMSO 349.52
    n-butyl acetate 4.37
    n-octanol 4.54
    chloroform 2.94
    n-propyl acetate 3.66
    acetic acid 24.2
    dichloromethane 6.59
    cyclohexanone 13.59
    propylene glycol 13.12
    isopropyl acetate 2.97
    DMAc 113.97
    2-ethoxyethanol 22.3
    isopentanol 5.58
    n-heptane 2.08
    ethyl formate 9.6
    1,2-dichloroethane 8.64
    n-hexanol 4.85
    2-methoxyethanol 45.87
    isobutyl acetate 1.31
    tetrachloromethane 1.07
    n-pentyl acetate 3.46
    transcutol 31.37
    n-heptanol 3.96
    ethylbenzene 0.92
    MIBK 3.18
    2-propoxyethanol 14.87
    tert-butanol 11.51
    MTBE 6.1
    2-butoxyethanol 9.49
    propionic acid 15.17
    o-xylene 2.18
    formic acid 50.67
    diethyl ether 7.0
    m-xylene 1.14
    p-xylene 1.01
    chlorobenzene 1.16
    dimethyl carbonate 7.28
    n-octane 0.97
    formamide 81.18
    cyclopentanone 16.64
    2-pentanone 7.12
    anisole 2.63
    cyclopentyl methyl ether 6.51
    gamma-butyrolactone 23.23
    1-methoxy-2-propanol 23.17
    pyridine 11.67
    3-pentanone 8.27
    furfural 22.26
    n-dodecane 0.66
    diethylene glycol 22.91
    diisopropyl ether 1.78
    tert-amyl alcohol 9.41
    acetylacetone 7.77
    n-hexadecane 0.7
    acetophenone 4.74
    methyl propionate 10.24
    isopentyl acetate 2.97
    trichloroethylene 6.09
    n-nonanol 4.13
    cyclohexanol 8.25
    benzyl alcohol 5.19
    2-ethylhexanol 3.3
    isooctanol 2.94
    dipropyl ether 5.03
    1,2-dichlorobenzene 1.41
    ethyl lactate 5.91
    propylene carbonate 7.52
    n-methylformamide 54.96
    2-pentanol 5.12
    n-pentane 1.57
    1-propoxy-2-propanol 10.7
    1-methoxy-2-propyl acetate 6.11
    2-(2-methoxypropoxy) propanol 10.99
    mesitylene 1.05
    ε-caprolactone 12.12
    p-cymene 1.85
    epichlorohydrin 16.12
    1,1,1-trichloroethane 1.59
    2-aminoethanol 24.93
    morpholine-4-carbaldehyde 56.54
    sulfolane 59.25
    2,2,4-trimethylpentane 0.64
    2-methyltetrahydrofuran 11.02
    n-hexyl acetate 4.21
    isooctane 0.33
    2-(2-butoxyethoxy)ethanol 13.79
    sec-butyl acetate 1.82
    tert-butyl acetate 2.83
    decalin 0.58
    glycerin 28.1
    diglyme 26.14
    acrylic acid 19.54
    isopropyl myristate 2.12
    n-butyric acid 9.44
    acetyl acetate 3.03
    di(2-ethylhexyl) phthalate 2.57
    ethyl propionate 3.71
    nitromethane 44.82
    1,2-diethoxyethane 6.82
    benzonitrile 3.9
    trioctyl phosphate 2.83
    1-bromopropane 3.89
    gamma-valerolactone 26.03
    n-decanol 3.27
    triethyl phosphate 3.33
    4-methyl-2-pentanol 2.54
    propionitrile 8.52
    vinylene carbonate 7.22
    1,1,2-trichlorotrifluoroethane 23.41
    DMS 5.06
    cumene 0.89
    2-octanol 2.85
    2-hexanone 3.99
    octyl acetate 3.11
    limonene 3.24
    1,2-dimethoxyethane 23.29
    ethyl orthosilicate 2.91
    tributyl phosphate 2.88
    diacetone alcohol 8.72
    N,N-dimethylaniline 4.5
    acrylonitrile 14.96
    aniline 4.6
    1,3-propanediol 20.21
    bromobenzene 0.75
    dibromomethane 4.33
    1,1,2,2-tetrachloroethane 7.15
    2-methyl-cyclohexyl acetate 2.95
    tetrabutyl urea 6.34
    diisobutyl methanol 2.73
    2-phenylethanol 4.18
    styrene 1.05
    dioctyl adipate 3.91
    dimethyl sulfate 21.39
    ethyl butyrate 4.23
    methyl lactate 13.98
    butyl lactate 5.06
    diethyl carbonate 2.92
    propanediol butyl ether 9.74
    triethyl orthoformate 3.78
    p-tert-butyltoluene 1.73
    methyl 4-tert-butylbenzoate 6.41
    morpholine 25.08
    tert-butylamine 6.29
    n-dodecanol 2.71
    dimethoxymethane 26.93
    ethylene carbonate 6.0
    cyrene 12.85
    2-ethoxyethyl acetate 5.0
    2-ethylhexyl acetate 2.4
    1,2,4-trichlorobenzene 2.07
    4-methylpyridine 7.24
    dibutyl ether 3.4
    2,6-dimethyl-4-heptanol 2.73
    DEF 25.15
    dimethyl isosorbide 13.0
    tetrachloroethylene 5.87
    eugenol 7.24
    triacetin 5.72
    span 80 7.46
    1,4-butanediol 10.17
    1,1-dichloroethane 2.84
    2-methyl-1-pentanol 3.73
    methyl formate 30.5
    2-methyl-1-butanol 5.68
    n-decane 1.0
    butyronitrile 5.78
    3,7-dimethyl-1-octanol 3.08
    1-chlorooctane 1.88
    1-chlorotetradecane 1.0
    n-nonane 1.02
    undecane 0.8
    tert-butylcyclohexane 0.39
    cyclooctane 0.97
    cyclopentanol 10.08
    tetrahydropyran 9.08
    tert-amyl methyl ether 6.37
    2,5,8-trioxanonane 21.21
    1-hexene 1.39
    2-isopropoxyethanol 10.68
    2,2,2-trifluoroethanol 16.16
    methyl butyrate 5.71

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction