Nitric Oxide

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  • Identifiers

    CAS number
    10102-43-9

    Molecular formula
    NO

    SMILES
    [N]=O

    Safety labels

    Oxidizer
    Oxidizer

    Compressed Gas
    Compressed Gas

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 93.16%
    Pungent 24.59%
    Sharp 21.1%
    Burnt 16.14%
    Bitter 15.7%
    Sour 15.62%
    Ethereal 11.01%
    Fermented 10.05%
    Caramellic 9.8%
    Malty 9.68%

     

    Flavor
    Odorless 56.81%
    Pungent 37.07%
    Bitter 30.43%
    Vinegar 26.41%
    Rotten 26.23%
    Formyl 25.76%
    Mustard 24.56%
    Sulfur 21.48%
    Decomposing cabbage 20.66%
    Mousy 19.49%

     

    Odor impact est.
    Low

    Odor threshold

    • Odor Threshold Low: 0.29 [ppm]. Odor Threshold High: 0.97 [ppm]. Odor thresholds from HSDB
    • Low odor threshold 0.3600 mg/cu m; High odor threshold 1.2000 mg/cu m

  • Properties

    XLogP3-AA
    0.2

    pKa est.
    4.59 (weak acid)

    Molecular weight
    30.006 g/mol

    Melting point expt.

    • -262.5 °F (EPA, 1998)
    • -163.6 °C
    • -263 °F

    Boiling point

    • -241.1 °F at 760 mmHg (EPA, 1998)
    • -151.7 °C
    • -151.74 °C
    • -151.8 °C
    • -241 °F

    Flash point

    • 65.77 ˚C est.

    Solubility expt.

    • 5 % (NIOSH, 2024)
    • 94900 mg/L
    • 7.38 ml/ 100 ml water at 0 °C; 4.6 ml/ 100 ml water at 20 °C; 2.37 ml/ 100 ml water at 60 °C
    • 3.4 CC/100 CC SULFURIC ACID
    • 26.6 CC/100 CC ALCOHOL
    • SOL IN CARBON DISULFIDE, IRON SULFATE
    • Solubility in water, ml/100ml at 0 °C: 7.4
    • 5%

  • Synonyms

    • nitric oxide
    • nitrogen monoxide
    • Mononitrogen monoxide
    • INOmax
    • 10102-43-9
    • Nitrosyl radical
    • Amidogen, oxo-
    • Nitrogen oxide (NO)
    • nitrosyl
    • Nitric oxide trimer
    • monoxyde d'azote
    • nitrogen monooxide
    • oxoazanyl
    • Inovent
    • oxyde azotique
    • oxyde nitrique
    • oxido nitrico
    • Stickstoffmonoxid
    • monoxido de nitrogeno
    • EDRF
    • Stickstoff(II)-oxid
    • oxido de nitrogeno(II)
    • oxidonitrogen(.)
    • GENOSYL
    • CCRIS 4319
    • CHEBI:16480
    • HSDB 1246
    • OHM-11771
    • 31C4KY9ESH
    • [NO]
    • (.)NO
    • endothelium-derived relaxing factor
    • NO(.)
    • (NO)(.)
    • Oxide, Nitric
    • NITRIC OXIDE (MART.)
    • NITRIC OXIDE [MART.]
    • (NO)
    • Monoxide, Mononitrogen
    • NITRIC OXIDE (EP MONOGRAPH)
    • NITRIC OXIDE [EP MONOGRAPH]
    • Endogenous Nitrate Vasodilator
    • Nitrogen(II) oxide
    • Nitrate Vasodilator, Endogenous
    • Vasodilator, Endogenous Nitrate
    • Endothelium-Derived Nitric Oxide
    • INOmax (TN)
    • Nitric Oxide, Endothelium Derived
    • Nitric Oxide, Endothelium-Derived
    • Ulspira
    • Ntric Oxide
    • Nitric Oxide, Zinc
    • NOW st
    • Noxivent 101
    • Noxivent 102
    • OHM 11771
    • NOXIVENT
    • Nitric oxide, 98.5%
    • Nitric Oxide, Glutathione
    • NITRIC OXIDE (NO)
    • NITRIC OXIDE [MI]
    • Nitric oxide (JAN/USAN)
    • NITRIC OXIDE [JAN]
    • NITRIC OXIDE [HSDB]
    • NITRIC OXIDE [VANDF]
    • DTXCID90938
    • NITRIC OXIDE [WHO-DD]
    • CHEMBL1200689
    • NITRIC OXIDE [EMA EPAR]
    • Nitric Oxide, Zinc, Glutathione
    • Nitric Oxide, Vitamin D3, Zinc
    • Nitric Oxide, Zinc, Vitamin D3
    • Nitric Oxide, Sophoricoside, Zinc
    • NITRIC OXIDE [ORANGE BOOK]
    • Nitric Oxide, Niacinamide, Adenosine
    • DB00435
    • Nitric Oxide, Vitamin D3, Glutathione
    • Nitric Oxide, Zinc, N-Acetylglucosamine
    • Nitric Oxide, Niacinamide, Adenosine, Zinc
    • C00533
    • D00074
    • NO DENTAL CARE (Improves gum disease, gum health, breath)
    • NO Care (Helps improve matabolic disorder, Lettuce fermented powder)
    • Bio NO V Plus (Helps improve matabolic disorder, Bean sprout powder)
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    • Bio NO more Menopause (Helps improve menopouse and Immunity, Soybean fermented powder)
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    • Dr. GNO Warming Gel (Provides sense of heating and pain relieft, Fermented Cabbage Extract)
    • Dr. NOtatione Pet care (Helps improve metabolic disorder, Cabbage fermented powder)
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    • Top NO Care Ultra (Helps improve matabolic disorder, Lettuce fermented powder)
    • 233-271-0
    • Bio NO Brain Care (Helps improve Brain blood flow and body temperature, Fermented Garlic powder)
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    • Dr. GNO All-Care 100 (Brightening, Wrinckle care, and Moisturizing effect, Pain relief, Acne Treatment, Fermented Cabbage Extract)
    • Dr. GNO All-Care 50 (Brightening, Wrinckle care, and Moisturizing effect, Pain relief, Acne Treatment, Fermented Cabbage Extract)
    • Dr. GNO CLEANSER (Helps cleanse sensitive skin, clears skin troubles, especially acne, fermented cabbage extract, mesoporous silica nanoparticle, zinc)
    • Dr. GNO Concentrated Ampoule (Wound recovery, Burn wound recovery, Acne Treatment, Fermented Lettuce Extract Concentrate)
    • Dr. GNO Cooling Gel (Provides sense of cooling and pain relief, Acne Treatment, Fermented Cabbage Extract)
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    • Dr. GNO Essence (Brightening, Wrinckle care, and Moisturizing effect, Acne treatment, Fermented Lettuce Extract)
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    • Dr. GNO Refreshing Mist (For skin care, and dry skin, safe to use it in the eye, Acne treatment, Fermented Sunflower seed Extract)
    • Dr. NO I (Wound recovery, Burn wound recovery, Acne Treatment, Fermented Lettuce Extract Concentrate)
    • Dr. NO II (Wound recovery, Burn wound recovery, Acne Treatmentm Fermented Lettuce Extract Concentrate)
    • IBSIBD NO 180 Start (Helps improve intestinal healthy and immunity, Lettuce and Soybean fermented powder)
    • NO MORE DRIP FOR NOSE COMFORT (Relieves nasal congestion, sinus congestion, rehydrate nasal passages, allergy relief, concentrated lettuce fermentation)
    • NO more Eye Pain (Relieves dryness of the eye, Protects against irritaion of the eye) redness of the eye, Concentrated Cabbage fermentation solubles)

  • Applications

    Nitric Oxide (CAS 10102-43-9) is primarily encountered as an industrially relevant reactive gas and intermediate in several applications. In large-scale manufacturing, it serves as a key intermediate in the Ostwald process for nitric acid production, where NO is oxidized to NO2 and ultimately to HNO3. In chemical synthesis, NO acts as a nitrosylating agent and a source of nitroso groups, enabling the preparation of metal nitrosyl complexes and various organic nitroso compounds. In coordination chemistry and catalysis, metal nitrosyl complexes derived from NO are studied as catalysts and functional materials. In biochemical research, NO is widely explored as a signaling molecule; related NO donors and controlled-release systems are used in laboratory investigations to study signaling pathways. These uses are primarily in laboratory-scale synthesis, catalysis, and research contexts, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 52.01
    methanol 106.65
    isopropanol 36.96
    water 74.88
    ethyl acetate 11.27
    n-propanol 33.73
    acetone 38.42
    n-butanol 25.84
    acetonitrile 27.85
    DMF 390.3
    toluene 2.44
    isobutanol 23.81
    1,4-dioxane 37.76
    methyl acetate 23.04
    THF 40.02
    2-butanone 21.93
    n-pentanol 18.58
    sec-butanol 25.21
    n-hexane 0.87
    ethylene glycol 70.04
    NMP 179.07
    cyclohexane 1.06
    DMSO 241.79
    n-butyl acetate 7.78
    n-octanol 8.55
    chloroform 4.27
    n-propyl acetate 8.69
    acetic acid 62.28
    dichloromethane 7.04
    cyclohexanone 21.83
    propylene glycol 43.44
    isopropyl acetate 6.7
    DMAc 219.2
    2-ethoxyethanol 45.62
    isopentanol 20.2
    n-heptane 1.28
    ethyl formate 19.3
    1,2-dichloroethane 7.86
    n-hexanol 11.1
    2-methoxyethanol 93.19
    isobutyl acetate 5.23
    tetrachloromethane 1.7
    n-pentyl acetate 6.74
    transcutol 60.77
    n-heptanol 8.08
    ethylbenzene 1.61
    MIBK 8.74
    2-propoxyethanol 30.54
    tert-butanol 41.24
    MTBE 15.55
    2-butoxyethanol 20.14
    propionic acid 38.86
    o-xylene 3.79
    formic acid 95.14
    diethyl ether 12.22
    m-xylene 2.7
    p-xylene 2.43
    chlorobenzene 2.96
    dimethyl carbonate 20.07
    n-octane 0.57
    formamide 105.83
    cyclopentanone 32.54
    2-pentanone 14.07
    anisole 8.57
    cyclopentyl methyl ether 14.61
    gamma-butyrolactone 43.64
    1-methoxy-2-propanol 55.84
    pyridine 21.31
    3-pentanone 11.93
    furfural 47.22
    n-dodecane 0.6
    diethylene glycol 43.8
    diisopropyl ether 3.39
    tert-amyl alcohol 30.11
    acetylacetone 14.68
    n-hexadecane 0.62
    acetophenone 10.16
    methyl propionate 19.34
    isopentyl acetate 6.76
    trichloroethylene 9.37
    n-nonanol 7.56
    cyclohexanol 15.77
    benzyl alcohol 11.91
    2-ethylhexanol 6.42
    isooctanol 6.45
    dipropyl ether 7.15
    1,2-dichlorobenzene 3.61
    ethyl lactate 11.64
    propylene carbonate 18.15
    n-methylformamide 124.44
    2-pentanol 14.74
    n-pentane 1.36
    1-propoxy-2-propanol 20.47
    1-methoxy-2-propyl acetate 11.76
    2-(2-methoxypropoxy) propanol 22.8
    mesitylene 2.29
    ε-caprolactone 19.88
    p-cymene 2.53
    epichlorohydrin 29.74
    1,1,1-trichloroethane 3.45
    2-aminoethanol 70.08
    morpholine-4-carbaldehyde 121.92
    sulfolane 67.3
    2,2,4-trimethylpentane 1.18
    2-methyltetrahydrofuran 23.04
    n-hexyl acetate 8.91
    isooctane 0.77
    2-(2-butoxyethoxy)ethanol 26.83
    sec-butyl acetate 4.84
    tert-butyl acetate 7.89
    decalin 0.71
    glycerin 72.09
    diglyme 49.05
    acrylic acid 49.38
    isopropyl myristate 4.12
    n-butyric acid 24.24
    acetyl acetate 6.35
    di(2-ethylhexyl) phthalate 6.88
    ethyl propionate 8.09
    nitromethane 90.73
    1,2-diethoxyethane 12.3
    benzonitrile 9.97
    trioctyl phosphate 5.55
    1-bromopropane 3.88
    gamma-valerolactone 55.51
    n-decanol 6.02
    triethyl phosphate 5.8
    4-methyl-2-pentanol 8.49
    propionitrile 18.58
    vinylene carbonate 19.36
    1,1,2-trichlorotrifluoroethane 42.97
    DMS 10.54
    cumene 1.91
    2-octanol 5.6
    2-hexanone 9.54
    octyl acetate 6.23
    limonene 3.85
    1,2-dimethoxyethane 58.06
    ethyl orthosilicate 5.27
    tributyl phosphate 5.71
    diacetone alcohol 20.45
    N,N-dimethylaniline 11.32
    acrylonitrile 30.82
    aniline 11.23
    1,3-propanediol 52.74
    bromobenzene 1.72
    dibromomethane 3.79
    1,1,2,2-tetrachloroethane 9.39
    2-methyl-cyclohexyl acetate 5.72
    tetrabutyl urea 10.44
    diisobutyl methanol 4.55
    2-phenylethanol 8.73
    styrene 2.12
    dioctyl adipate 7.58
    dimethyl sulfate 40.88
    ethyl butyrate 7.01
    methyl lactate 27.78
    butyl lactate 10.03
    diethyl carbonate 5.69
    propanediol butyl ether 23.85
    triethyl orthoformate 6.48
    p-tert-butyltoluene 2.54
    methyl 4-tert-butylbenzoate 13.25
    morpholine 55.3
    tert-butylamine 18.41
    n-dodecanol 4.75
    dimethoxymethane 71.49
    ethylene carbonate 14.63
    cyrene 22.43
    2-ethoxyethyl acetate 10.89
    2-ethylhexyl acetate 5.13
    1,2,4-trichlorobenzene 4.86
    4-methylpyridine 20.13
    dibutyl ether 5.13
    2,6-dimethyl-4-heptanol 4.55
    DEF 45.83
    dimethyl isosorbide 24.28
    tetrachloroethylene 7.57
    eugenol 16.26
    triacetin 11.43
    span 80 17.35
    1,4-butanediol 28.9
    1,1-dichloroethane 4.57
    2-methyl-1-pentanol 14.23
    methyl formate 71.13
    2-methyl-1-butanol 20.58
    n-decane 0.79
    butyronitrile 15.08
    3,7-dimethyl-1-octanol 7.06
    1-chlorooctane 2.27
    1-chlorotetradecane 1.34
    n-nonane 0.74
    undecane 0.67
    tert-butylcyclohexane 0.8
    cyclooctane 0.48
    cyclopentanol 23.15
    tetrahydropyran 17.98
    tert-amyl methyl ether 13.3
    2,5,8-trioxanonane 39.12
    1-hexene 2.61
    2-isopropoxyethanol 26.0
    2,2,2-trifluoroethanol 37.38
    methyl butyrate 12.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction