N1,N3-Bis(2,2,6,6-tetramethylpiperidin-4-YL)isophthalamide

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  • Identifiers

    CAS number
    42774-15-2

    Molecular formula
    C26H42N4O2

    SMILES
    CC1(CC(CC(N1)(C)C)NC(=O)C2=CC(=CC=C2)C(=O)NC3CC(NC(C3)(C)C)(C)C)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 47.71%
    Cooling 32.15%
    Animal 26.12%
    Savory 25.11%
    Roasted 23.34%
    Meaty 22.21%
    Mint 21.72%
    Cooked 19.12%
    Fishy 17.35%
    Bitter 16.53%

     

    Flavor
    Bitter 50.68%
    Odorless 25.3%
    Fruity 22.63%
    Mild 21.63%
    Cedarleaf 20.82%
    Sandalwood 20.09%
    Heather 19.92%
    Fir 19.68%
    Orange flower 19.56%
    Broom 19.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    9.14 (weak base)

    Molecular weight
    442.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    452°C

    Flash point

    • 224.01 ˚C est.

  • Synonyms

    • 42774-15-2
    • N1,N3-Bis(2,2,6,6-tetramethylpiperidin-4-yl)isophthalamide
    • N,N'-BIS(2,2,6,6-TETRAMETHYL-4-PIPERIDINYL)-1,3-BENZENEDICARBOXAMIDE
    • 1,3-Benzenedicarboxamide, N,N'-bis(2,2,6,6-tetramethyl-4-piperidinyl)-
    • ZJD6FK539H
    • N,N'-Bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide
    • NYLOSTAB S-EED
    • DTXSID3068417
    • EC 419-710-0
    • 1,3-Benzenedicarboxamide, N1,N3-bis(2,2,6,6-tetramethyl-4-piperidinyl)-
    • n,n'-bis(2,2,6,6-tetramethyl-4-piperidinyl)isophthalamide
    • RefChem:831304
    • DTXCID2040159
    • 419-710-0
    • MFCD09751152
    • C26H42N4O2
    • 1-N,3-N-bis(2,2,6,6-tetramethylpiperidin-4-yl)benzene-1,3-dicarboxamide
    • N1,N3-bis(2,2,6,6-tetramethylpiperidin-4-yl)benzene-1,3-dicarboxamide
    • UNII-ZJD6FK539H
    • SCHEMBL310763
    • OYNOCRWQLLIRON-UHFFFAOYSA-N
    • AKOS022173010
    • DS-7146
    • SY316622
    • B6154
    • CS-0162605
    • NS00006860
    • D83388
    • 774B152
    • N1,N3-Bis(2,2,6,6-tetramethyl-4-piperidyl)isophthalamide
    • N,N'-BIS(2,2,6,6-TETRAMETHYL-4-PIPERIDINYL) ISOPHTHALAMIDE
    • N1,N3-bis(2,2,6,6-tetramethyl-4-piperidyl)benzene-1,3-dicarboxamide
    • N~1~,N~3~-Bis(2,2,6,6-tetramethylpiperidin-4-yl)benzene-1,3-dicarboxamide
    • 42774-15-2

  • Applications

    N1,N3-Bis(2,2,6,6-tetramethylpiperidin-4-YL)isophthalamide (CAS 42774-15-2) is a bis derivative of isophthalamide bearing two hindered amine moieties, designed as a HALS type stabilizer for polymer systems to suppress photooxidative degradation. In practical formulations it is used in polymers/plastics and coatings/inks to extend aging resistance under light and heat, and may be incorporated into adhesive formulations and packaging materials to improve stability, with a role as a stabilizer or radical scavenger rather than a crosslinking agent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 44.15
    methanol 78.27
    isopropanol 16.9
    water 6.16
    ethyl acetate 66.43
    n-propanol 39.44
    acetone 49.68
    n-butanol 22.93
    acetonitrile 20.96
    DMF 277.98
    toluene 14.99
    isobutanol 24.87
    1,4-dioxane 25.82
    methyl acetate 81.59
    THF 133.33
    2-butanone 70.16
    n-pentanol 17.4
    sec-butanol 22.6
    n-hexane 1.04
    ethylene glycol 25.54
    NMP 877.48
    cyclohexane 0.75
    DMSO 121.25
    n-butyl acetate 43.0
    n-octanol 9.5
    chloroform 127.01
    n-propyl acetate 48.61
    acetic acid 306.01
    dichloromethane 106.82
    cyclohexanone 81.89
    propylene glycol 52.27
    isopropyl acetate 38.65
    DMAc 556.33
    2-ethoxyethanol 75.3
    isopentanol 15.45
    n-heptane 0.96
    ethyl formate 56.38
    1,2-dichloroethane 45.16
    n-hexanol 15.68
    2-methoxyethanol 131.08
    isobutyl acetate 35.61
    tetrachloromethane 15.9
    n-pentyl acetate 38.55
    transcutol 141.14
    n-heptanol 13.67
    ethylbenzene 4.57
    MIBK 26.74
    2-propoxyethanol 104.95
    tert-butanol 12.73
    MTBE 12.97
    2-butoxyethanol 65.11
    propionic acid 156.98
    o-xylene 9.89
    formic acid 238.94
    diethyl ether 14.0
    m-xylene 12.2
    p-xylene 6.94
    chlorobenzene 20.25
    dimethyl carbonate 90.1
    n-octane 0.38
    formamide 204.36
    cyclopentanone 189.0
    2-pentanone 48.52
    anisole 13.24
    cyclopentyl methyl ether 58.7
    gamma-butyrolactone 424.89
    1-methoxy-2-propanol 108.2
    pyridine 65.09
    3-pentanone 46.75
    furfural 248.61
    n-dodecane 0.2
    diethylene glycol 60.5
    diisopropyl ether 4.05
    tert-amyl alcohol 21.06
    acetylacetone 73.51
    n-hexadecane 0.22
    acetophenone 35.17
    methyl propionate 127.48
    isopentyl acetate 35.64
    trichloroethylene 174.04
    n-nonanol 9.27
    cyclohexanol 20.25
    benzyl alcohol 26.17
    2-ethylhexanol 10.22
    isooctanol 11.26
    dipropyl ether 13.87
    1,2-dichlorobenzene 20.07
    ethyl lactate 54.34
    propylene carbonate 192.42
    n-methylformamide 195.2
    2-pentanol 13.11
    n-pentane 0.98
    1-propoxy-2-propanol 69.21
    1-methoxy-2-propyl acetate 92.53
    2-(2-methoxypropoxy) propanol 57.67
    mesitylene 4.61
    ε-caprolactone 145.86
    p-cymene 4.82
    epichlorohydrin 234.68
    1,1,1-trichloroethane 44.45
    2-aminoethanol 60.91
    morpholine-4-carbaldehyde 310.85
    sulfolane 468.49
    2,2,4-trimethylpentane 0.91
    2-methyltetrahydrofuran 71.69
    n-hexyl acetate 38.0
    isooctane 0.38
    2-(2-butoxyethoxy)ethanol 57.73
    sec-butyl acetate 30.19
    tert-butyl acetate 33.39
    decalin 0.6
    glycerin 100.22
    diglyme 113.87
    acrylic acid 176.98
    isopropyl myristate 7.23
    n-butyric acid 118.17
    acetyl acetate 48.54
    di(2-ethylhexyl) phthalate 19.99
    ethyl propionate 45.48
    nitromethane 327.18
    1,2-diethoxyethane 19.39
    benzonitrile 21.28
    trioctyl phosphate 12.21
    1-bromopropane 18.41
    gamma-valerolactone 345.07
    n-decanol 5.16
    triethyl phosphate 22.42
    4-methyl-2-pentanol 7.54
    propionitrile 21.16
    vinylene carbonate 163.3
    1,1,2-trichlorotrifluoroethane 343.01
    DMS 59.84
    cumene 3.82
    2-octanol 7.33
    2-hexanone 31.12
    octyl acetate 14.02
    limonene 6.23
    1,2-dimethoxyethane 52.44
    ethyl orthosilicate 19.13
    tributyl phosphate 15.44
    diacetone alcohol 60.58
    N,N-dimethylaniline 13.99
    acrylonitrile 40.36
    aniline 32.04
    1,3-propanediol 52.69
    bromobenzene 16.03
    dibromomethane 50.47
    1,1,2,2-tetrachloroethane 115.37
    2-methyl-cyclohexyl acetate 29.75
    tetrabutyl urea 20.38
    diisobutyl methanol 3.83
    2-phenylethanol 25.63
    styrene 4.57
    dioctyl adipate 17.84
    dimethyl sulfate 207.93
    ethyl butyrate 34.38
    methyl lactate 128.31
    butyl lactate 56.74
    diethyl carbonate 21.2
    propanediol butyl ether 57.05
    triethyl orthoformate 26.65
    p-tert-butyltoluene 4.83
    methyl 4-tert-butylbenzoate 64.47
    morpholine 70.08
    tert-butylamine 5.26
    n-dodecanol 2.83
    dimethoxymethane 108.3
    ethylene carbonate 105.45
    cyrene 95.43
    2-ethoxyethyl acetate 78.23
    2-ethylhexyl acetate 30.17
    1,2,4-trichlorobenzene 38.65
    4-methylpyridine 61.16
    dibutyl ether 5.86
    2,6-dimethyl-4-heptanol 3.83
    DEF 101.52
    dimethyl isosorbide 115.83
    tetrachloroethylene 76.25
    eugenol 52.08
    triacetin 88.9
    span 80 48.38
    1,4-butanediol 21.12
    1,1-dichloroethane 43.75
    2-methyl-1-pentanol 13.41
    methyl formate 139.42
    2-methyl-1-butanol 22.96
    n-decane 0.5
    butyronitrile 16.37
    3,7-dimethyl-1-octanol 7.76
    1-chlorooctane 3.72
    1-chlorotetradecane 0.85
    n-nonane 0.48
    undecane 0.3
    tert-butylcyclohexane 0.72
    cyclooctane 0.42
    cyclopentanol 44.07
    tetrahydropyran 23.93
    tert-amyl methyl ether 20.66
    2,5,8-trioxanonane 61.51
    1-hexene 4.01
    2-isopropoxyethanol 49.46
    2,2,2-trifluoroethanol 188.39
    methyl butyrate 58.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction