N1-(4-Aminobutyl)-1,4-butanediamine

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  • Identifiers

    CAS number
    4427-76-3

    Molecular formula
    C8H21N3

    SMILES
    C(CCNCCCCN)CN

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Fishy 88.19%
    Cheesy 52.93%
    Ripe 47.55%
    Animal 36.19%
    Odorless 32.56%
    Meaty 23.23%
    Savory 19.19%
    Pungent 15.37%
    Oily 14.43%
    Cooked 13.59%

     

    Flavor
    Ammoniacal 30.96%
    Fishy 29.54%
    Odorless 25.33%
    Meaty 21.46%
    Sulfurous 21.4%
    Glue 19.88%
    Skunky 19.86%
    Bloody 19.57%
    Bland 19.56%
    Ammonia 19.2%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    5.81 (weak acid)

    Molecular weight
    159.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    271°C

    Flash point

    • 123.72 ˚C est.

  • Synonyms

    • sym-homospermidine
    • 4427-76-3
    • 1,4-Butanediamine, N-(4-aminobutyl)-
    • N-(4-aminobutyl)-1,4-butanediamine
    • 1,6,11-triazaundecane
    • 0IJ25X1H4R
    • CHEBI:16554
    • DTXSID00196098
    • N1-(4-Aminobutyl)-1,4-butanediamine
    • RefChem:890093
    • DTXCID10118589
    • bis(4-aminobutyl)amine
    • Homospermidine
    • N1-(4-aminobutyl)butane-1,4-diamine
    • N-(4-aminobutyl)butane-1,4-diamine
    • N'-(4-aminobutyl)butane-1,4-diamine
    • 4,4'-Diaminodibutylamine
    • 1,9-diamino-5-azanonane
    • CHEMBL36119
    • MFCD20547437
    • UNII-0IJ25X1H4R
    • SCHEMBL138047
    • SCHEMBL5499049
    • 4,4'-IMINOBIS(BUTYLAMINE)
    • BDBM50032505
    • n-(4-aminobutyl)-1,4-diaminobutane
    • AKOS015855215
    • DIBUTYLAMINE, 4,4'-DIAMINO-
    • EBC-612827
    • N~1~-(4-Aminobutyl)butane-1,4-diamine
    • SY423266
    • N-(4-Aminobutyl)-1,4-butanediamine, 9CI
    • C06366
    • G66120
    • 1,4-BUTANEDIAMINE, N1-(4-AMINOBUTYL)-
    • EN300-7434636
    • Q3882311
    • 4427-76-3

  • Applications

    N1-(4-Aminobutyl)-1,4-butanediamine (CAS 4427-76-3) is a reactive diamine used primarily as a curing agent and crosslinker in polymer systems. It functions as a bifunctional building block for epoxy resins, providing amine groups that drive network formation in coatings, adhesives, and composite materials. It is also employed as a polyfunctional intermediate in the synthesis of specialty polymers and polyurethanes, enabling tailored mechanical and thermal properties. In addition, it serves as an intermediate in the manufacture of pharmaceutical and fine chemicals, and may be used in formulations of coatings, inks, and sealants to adjust cure rates and network structure. Depending on regulatory and formulation limits, it can be considered for electronics-related epoxy systems and other high-performance applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 460.72
    methanol 1363.07
    isopropanol 172.37
    water 90.02
    ethyl acetate 89.43
    n-propanol 363.29
    acetone 123.27
    n-butanol 291.14
    acetonitrile 96.63
    DMF 391.3
    toluene 19.51
    isobutanol 174.61
    1,4-dioxane 181.4
    methyl acetate 81.62
    THF 488.82
    2-butanone 82.58
    n-pentanol 126.71
    sec-butanol 121.78
    n-hexane 5.78
    ethylene glycol 399.17
    NMP 510.05
    cyclohexane 18.15
    DMSO 885.6
    n-butyl acetate 109.01
    n-octanol 29.0
    chloroform 246.08
    n-propyl acetate 63.2
    acetic acid 1450.17
    dichloromethane 169.37
    cyclohexanone 271.2
    propylene glycol 321.61
    isopropyl acetate 43.33
    DMAc 220.64
    2-ethoxyethanol 303.54
    isopentanol 128.46
    n-heptane 14.03
    ethyl formate 235.97
    1,2-dichloroethane 98.61
    n-hexanol 139.59
    2-methoxyethanol 752.23
    isobutyl acetate 35.53
    tetrachloromethane 76.52
    n-pentyl acetate 45.28
    transcutol 233.28
    n-heptanol 65.65
    ethylbenzene 6.68
    MIBK 26.31
    2-propoxyethanol 340.88
    tert-butanol 123.19
    MTBE 30.63
    2-butoxyethanol 188.98
    propionic acid 564.92
    o-xylene 13.62
    formic acid 1310.05
    diethyl ether 46.63
    m-xylene 11.84
    p-xylene 9.9
    chlorobenzene 58.11
    dimethyl carbonate 44.49
    n-octane 3.85
    formamide 915.29
    cyclopentanone 451.3
    2-pentanone 71.17
    anisole 22.19
    cyclopentyl methyl ether 147.55
    gamma-butyrolactone 721.62
    1-methoxy-2-propanol 302.2
    pyridine 201.55
    3-pentanone 50.69
    furfural 616.03
    n-dodecane 1.85
    diethylene glycol 346.7
    diisopropyl ether 8.49
    tert-amyl alcohol 91.56
    acetylacetone 82.2
    n-hexadecane 1.94
    acetophenone 39.96
    methyl propionate 99.46
    isopentyl acetate 60.91
    trichloroethylene 215.28
    n-nonanol 26.78
    cyclohexanol 183.6
    benzyl alcohol 71.26
    2-ethylhexanol 56.22
    isooctanol 38.14
    dipropyl ether 63.06
    1,2-dichlorobenzene 57.01
    ethyl lactate 86.41
    propylene carbonate 327.88
    n-methylformamide 625.27
    2-pentanol 83.8
    n-pentane 8.33
    1-propoxy-2-propanol 204.86
    1-methoxy-2-propyl acetate 94.37
    2-(2-methoxypropoxy) propanol 56.75
    mesitylene 7.97
    ε-caprolactone 265.22
    p-cymene 13.49
    epichlorohydrin 316.3
    1,1,1-trichloroethane 74.24
    2-aminoethanol 565.12
    morpholine-4-carbaldehyde 368.13
    sulfolane 783.17
    2,2,4-trimethylpentane 4.09
    2-methyltetrahydrofuran 196.1
    n-hexyl acetate 36.96
    isooctane 2.13
    2-(2-butoxyethoxy)ethanol 100.57
    sec-butyl acetate 26.64
    tert-butyl acetate 37.92
    decalin 4.42
    glycerin 538.98
    diglyme 210.15
    acrylic acid 562.44
    isopropyl myristate 11.18
    n-butyric acid 727.78
    acetyl acetate 79.32
    di(2-ethylhexyl) phthalate 28.82
    ethyl propionate 46.4
    nitromethane 800.91
    1,2-diethoxyethane 53.2
    benzonitrile 67.09
    trioctyl phosphate 24.13
    1-bromopropane 42.41
    gamma-valerolactone 562.07
    n-decanol 18.08
    triethyl phosphate 41.37
    4-methyl-2-pentanol 27.98
    propionitrile 102.72
    vinylene carbonate 268.86
    1,1,2-trichlorotrifluoroethane 631.19
    DMS 35.71
    cumene 6.28
    2-octanol 22.01
    2-hexanone 41.14
    octyl acetate 19.94
    limonene 22.25
    1,2-dimethoxyethane 200.32
    ethyl orthosilicate 40.91
    tributyl phosphate 30.72
    diacetone alcohol 85.99
    N,N-dimethylaniline 19.7
    acrylonitrile 165.7
    aniline 109.76
    1,3-propanediol 618.35
    bromobenzene 39.74
    dibromomethane 100.56
    1,1,2,2-tetrachloroethane 200.73
    2-methyl-cyclohexyl acetate 47.04
    tetrabutyl urea 33.76
    diisobutyl methanol 21.5
    2-phenylethanol 72.12
    styrene 11.66
    dioctyl adipate 25.16
    dimethyl sulfate 110.43
    ethyl butyrate 75.84
    methyl lactate 162.54
    butyl lactate 81.97
    diethyl carbonate 45.27
    propanediol butyl ether 110.76
    triethyl orthoformate 70.11
    p-tert-butyltoluene 13.73
    methyl 4-tert-butylbenzoate 45.6
    morpholine 333.06
    tert-butylamine 57.02
    n-dodecanol 13.09
    dimethoxymethane 142.89
    ethylene carbonate 233.87
    cyrene 111.56
    2-ethoxyethyl acetate 53.65
    2-ethylhexyl acetate 48.31
    1,2,4-trichlorobenzene 70.44
    4-methylpyridine 103.38
    dibutyl ether 22.82
    2,6-dimethyl-4-heptanol 21.5
    DEF 151.05
    dimethyl isosorbide 127.31
    tetrachloroethylene 224.1
    eugenol 63.9
    triacetin 52.73
    span 80 83.77
    1,4-butanediol 208.56
    1,1-dichloroethane 62.44
    2-methyl-1-pentanol 61.41
    methyl formate 368.01
    2-methyl-1-butanol 130.83
    n-decane 3.29
    butyronitrile 108.27
    3,7-dimethyl-1-octanol 22.76
    1-chlorooctane 11.3
    1-chlorotetradecane 4.16
    n-nonane 3.38
    undecane 2.27
    tert-butylcyclohexane 3.57
    cyclooctane 5.92
    cyclopentanol 333.42
    tetrahydropyran 169.11
    tert-amyl methyl ether 27.26
    2,5,8-trioxanonane 120.49
    1-hexene 15.15
    2-isopropoxyethanol 115.29
    2,2,2-trifluoroethanol 476.93
    methyl butyrate 81.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction