N-Palmitoylglycine

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  • Identifiers

    CAS number
    2441-41-0

    Molecular formula
    C18H35NO3

    SMILES
    CCCCCCCCCCCCCCCC(=O)NCC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 43.38%
    Waxy 42.39%
    Odorless 38.31%
    Savory 34.15%
    Meaty 33.23%
    Oily 26.13%
    Milky 24.18%
    Citrus 23.43%
    Fishy 22.5%
    Animal 21.52%

     

    Flavor
    Fatty 40.73%
    Odorless 39.22%
    Bland 35.76%
    Mild 35.59%
    Waxy 31.93%
    Faint 28.46%
    Oily 24.33%
    Slightly waxy 23.54%
    Fat 23.51%
    Bay oil 22.66%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.5

    pKa est.
    7.2 (neutral)

    Molecular weight
    313.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    374°C

    Flash point

    • 221.89 ˚C est.

  • Synonyms

    • N-Palmitoylglycine
    • 2441-41-0
    • 2-(hexadecanoylamino)acetic acid
    • N-Palmitoyl glycine
    • N-HEXADECANOYLGLYCINE
    • Elmiric acid
    • N-(1-Oxohexadecyl)glycine
    • N-hexadecanoyl-glycine
    • M6V3RIU5KI
    • Glycine, N-(1-oxohexadecyl)-
    • N-Ethanoyl-Hexadecanamide
    • CHEBI:39540
    • DTXSID40179163
    • RefChem:927307
    • DTXCID70101654
    • 627-023-4
    • Palmitoylglycine
    • palmitoyl glycine
    • palmitoyl-glycine
    • PALGLY
    • MFCD00153471
    • 2-hexadecanamidoacetic acid
    • C18H35NO3
    • UNII-M6V3RIU5KI
    • Glycine,N-(1-oxohexadecyl)-
    • N-palmitoyl-Gly
    • hexadecanoylglycine
    • n-palmitoyl-glycine
    • Pal-Gly-OH
    • TIMECODE
    • PALMITOILGLICINA
    • 2-Palmitamidoacetic Acid
    • N-palmitoylglycine (NPG)
    • N-palmitoylglycine, powder
    • EC 627-023-4
    • N-(1-oxooctadecyl)-Glycine
    • SCHEMBL515102
    • CHEMBL226117
    • orb1693057
    • BDBM212439
    • HMS3604M20
    • PalGly, >=98% (HPLC), solid
    • LMFA08020079
    • AKOS021983458
    • DB03440
    • FP49073
    • HY-W074890
    • NCGC00161199-02
    • BS-27751
    • SY277780
    • DB-255909
    • CS-0111614
    • NS00070468
    • ST50976886
    • D76997
    • F493041
    • Q27094364
    • 2441-41-0

  • Applications

    N-Palmitoylglycine (CAS 2441-41-0) is a fatty acyl glycine amide used as an intermediate in organic synthesis and as a surface-active agent. In industry, it may be employed as a surfactant/emulsifier in cosmetics and personal care formulations and in household cleaning products; it can serve as a processing aid or additive in polymers and coatings; it is evaluated as a lipid-like intermediate for pharmaceutical research and development; and, subject to local regulations and formulation limits, it may function as a building block for specialty chemical syntheses in industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.37
    methanol 21.47
    isopropanol 12.89
    water 0.04
    ethyl acetate 15.47
    n-propanol 12.66
    acetone 21.14
    n-butanol 12.09
    acetonitrile 6.55
    DMF 88.29
    toluene 7.21
    isobutanol 11.23
    1,4-dioxane 27.74
    methyl acetate 17.61
    THF 119.43
    2-butanone 26.87
    n-pentanol 15.44
    sec-butanol 13.6
    n-hexane 1.9
    ethylene glycol 2.14
    NMP 178.22
    cyclohexane 3.27
    DMSO 182.38
    n-butyl acetate 34.57
    n-octanol 13.44
    chloroform 56.3
    n-propyl acetate 40.26
    acetic acid 22.89
    dichloromethane 57.95
    cyclohexanone 89.99
    propylene glycol 6.88
    isopropyl acetate 24.22
    DMAc 200.85
    2-ethoxyethanol 45.81
    isopentanol 18.44
    n-heptane 1.39
    ethyl formate 15.25
    1,2-dichloroethane 44.5
    n-hexanol 12.42
    2-methoxyethanol 41.75
    isobutyl acetate 31.12
    tetrachloromethane 11.43
    n-pentyl acetate 47.22
    transcutol 208.88
    n-heptanol 13.17
    ethylbenzene 9.42
    MIBK 31.82
    2-propoxyethanol 41.99
    tert-butanol 28.98
    MTBE 26.8
    2-butoxyethanol 48.57
    propionic acid 18.14
    o-xylene 11.21
    formic acid 8.88
    diethyl ether 10.19
    m-xylene 8.81
    p-xylene 14.28
    chlorobenzene 15.26
    dimethyl carbonate 9.72
    n-octane 1.13
    formamide 17.25
    cyclopentanone 107.51
    2-pentanone 24.15
    anisole 22.78
    cyclopentyl methyl ether 40.52
    gamma-butyrolactone 99.43
    1-methoxy-2-propanol 46.15
    pyridine 31.06
    3-pentanone 21.01
    furfural 80.98
    n-dodecane 0.81
    diethylene glycol 22.86
    diisopropyl ether 7.34
    tert-amyl alcohol 30.12
    acetylacetone 46.64
    n-hexadecane 0.94
    acetophenone 41.11
    methyl propionate 17.48
    isopentyl acetate 43.96
    trichloroethylene 78.27
    n-nonanol 14.24
    cyclohexanol 20.85
    benzyl alcohol 20.54
    2-ethylhexanol 12.63
    isooctanol 14.99
    dipropyl ether 15.59
    1,2-dichlorobenzene 23.38
    ethyl lactate 24.46
    propylene carbonate 58.95
    n-methylformamide 23.19
    2-pentanol 9.89
    n-pentane 0.95
    1-propoxy-2-propanol 41.13
    1-methoxy-2-propyl acetate 47.65
    2-(2-methoxypropoxy) propanol 56.44
    mesitylene 8.23
    ε-caprolactone 83.55
    p-cymene 9.0
    epichlorohydrin 90.7
    1,1,1-trichloroethane 40.46
    2-aminoethanol 8.31
    morpholine-4-carbaldehyde 105.13
    sulfolane 250.9
    2,2,4-trimethylpentane 2.19
    2-methyltetrahydrofuran 60.35
    n-hexyl acetate 48.16
    isooctane 1.26
    2-(2-butoxyethoxy)ethanol 72.18
    sec-butyl acetate 32.44
    tert-butyl acetate 49.59
    decalin 3.81
    glycerin 14.7
    diglyme 146.86
    acrylic acid 14.65
    isopropyl myristate 16.01
    n-butyric acid 33.39
    acetyl acetate 16.75
    di(2-ethylhexyl) phthalate 20.41
    ethyl propionate 26.58
    nitromethane 42.62
    1,2-diethoxyethane 49.15
    benzonitrile 20.53
    trioctyl phosphate 14.18
    1-bromopropane 19.79
    gamma-valerolactone 156.32
    n-decanol 9.11
    triethyl phosphate 26.53
    4-methyl-2-pentanol 11.06
    propionitrile 8.27
    vinylene carbonate 38.57
    1,1,2-trichlorotrifluoroethane 91.4
    DMS 29.84
    cumene 9.85
    2-octanol 11.01
    2-hexanone 39.38
    octyl acetate 20.35
    limonene 13.76
    1,2-dimethoxyethane 96.19
    ethyl orthosilicate 26.96
    tributyl phosphate 19.89
    diacetone alcohol 65.01
    N,N-dimethylaniline 24.26
    acrylonitrile 10.64
    aniline 11.9
    1,3-propanediol 15.13
    bromobenzene 16.41
    dibromomethane 35.68
    1,1,2,2-tetrachloroethane 91.66
    2-methyl-cyclohexyl acetate 41.98
    tetrabutyl urea 32.78
    diisobutyl methanol 10.96
    2-phenylethanol 18.67
    styrene 9.95
    dioctyl adipate 33.83
    dimethyl sulfate 38.24
    ethyl butyrate 33.33
    methyl lactate 19.65
    butyl lactate 44.17
    diethyl carbonate 20.68
    propanediol butyl ether 45.4
    triethyl orthoformate 33.0
    p-tert-butyltoluene 9.28
    methyl 4-tert-butylbenzoate 53.81
    morpholine 47.78
    tert-butylamine 16.4
    n-dodecanol 6.23
    dimethoxymethane 30.89
    ethylene carbonate 31.95
    cyrene 65.04
    2-ethoxyethyl acetate 57.85
    2-ethylhexyl acetate 34.05
    1,2,4-trichlorobenzene 32.42
    4-methylpyridine 31.82
    dibutyl ether 23.12
    2,6-dimethyl-4-heptanol 10.96
    DEF 49.63
    dimethyl isosorbide 116.85
    tetrachloroethylene 53.97
    eugenol 49.65
    triacetin 63.58
    span 80 44.77
    1,4-butanediol 8.36
    1,1-dichloroethane 29.08
    2-methyl-1-pentanol 21.17
    methyl formate 14.41
    2-methyl-1-butanol 15.9
    n-decane 1.74
    butyronitrile 11.35
    3,7-dimethyl-1-octanol 15.79
    1-chlorooctane 10.44
    1-chlorotetradecane 3.21
    n-nonane 1.56
    undecane 1.11
    tert-butylcyclohexane 3.36
    cyclooctane 1.16
    cyclopentanol 26.56
    tetrahydropyran 35.51
    tert-amyl methyl ether 26.43
    2,5,8-trioxanonane 94.13
    1-hexene 7.01
    2-isopropoxyethanol 38.52
    2,2,2-trifluoroethanol 12.96
    methyl butyrate 49.45

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction