N-Myristoylethanolamine

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  • Identifiers

    CAS number
    142-58-5

    Molecular formula
    C16H33NO2

    SMILES
    CCCCCCCCCCCCCC(=O)NCCO

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Waxy 36.06%
    Fatty 33.71%
    Savory 33.28%
    Meaty 32.58%
    Odorless 32.39%
    Fishy 31.28%
    Oily 28.71%
    Citrus 26.56%
    Fresh 26.43%
    Animal 24.94%

     

    Flavor
    Fatty 39.91%
    Mild 34.75%
    Odorless 34.05%
    Waxy 33.13%
    Bland 32.86%
    Faint 26.34%
    Fat 25.45%
    Oily 25.11%
    Slightly waxy 23.53%
    Bay oil 22.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    7.41 (neutral)

    Molecular weight
    271.44 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    391°C

    Flash point

    • 187.06 ˚C est.

  • Synonyms

    • 142-58-5
    • N-(2-HYDROXYETHYL)TETRADECANAMIDE
    • N-myristoylethanolamine
    • Tetradecanamide, N-(2-hydroxyethyl)-
    • Comperlan MM
    • Schercomid MME
    • Loramine MY 228
    • Myristyl monoethanolamide
    • Myristoyl monoethanolamide
    • 6CYG57WXZ0
    • Monoethanolamine myristic acid condensate
    • DTXSID0042452
    • RefChem:825500
    • DTXCID8022452
    • N-(2-Hydroxyethyl)myristamide
    • Myristic monoethanolamide
    • Myristamide MEA
    • myristoyl ethanolamide
    • Myristoyl-EA
    • Myristoyl-ethanolamine
    • N-(Tetradecanoyl)-ethanolamine
    • tetradecanoyl ethanolamide
    • CHEMBL5277451
    • UNII-6CYG57WXZ0
    • N-(tetradecanoyl)ethanolamine
    • HSDB 5640
    • EINECS 205-546-5
    • MFCD02670245
    • N-(myristoyl)ethanolamine
    • N-tetradecanoylethanolamine
    • SCHEMBL308261
    • GTPL5221
    • orb2813649
    • CHEBI:85262
    • NAE14:0
    • JHIXEZNTXMFXEK-UHFFFAOYSA-N
    • N-(2-hydroxyethyl)-tetradecanamide
    • NAE 14:0
    • BDBM50408838
    • LMFA08040042
    • AKOS002676442
    • AM 3165
    • BS-15372
    • HY-119723
    • CS-0077862
    • NS00013870
    • A10816
    • N-(2-HYDROXYETHYL)TETRADECANAMIDE [HSDB]
    • TETRADECANOIC ACID (2-HYDROXY-ETHYL)-AMIDE
    • Q27083876
    • 142-58-5

  • Applications

    N-Myristoylethanolamine (CAS 142-58-5) is primarily used as a lipid amide intermediate and as a research subject in endocannabinoid-like signaling studies. In cosmetics and personal care, it may be explored as a lipophilic emollient or skin-conditioning component in lipid-based formulations. In pharmaceutical research, it is commonly employed as a reference compound and precursor for the synthesis of related N-acyl ethanolamides and other bioactive lipids. In industrial manufacturing, it can serve as a building block for amide derivatives and is occasionally used as an analytical standard for methods targeting N-acyl ethanolamides.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 141.82
    methanol 244.84
    isopropanol 143.56
    water 0.06
    ethyl acetate 178.94
    n-propanol 139.33
    acetone 182.11
    n-butanol 147.59
    acetonitrile 68.04
    DMF 346.71
    toluene 44.71
    isobutanol 123.22
    1,4-dioxane 193.38
    methyl acetate 115.16
    THF 581.99
    2-butanone 184.78
    n-pentanol 115.08
    sec-butanol 126.4
    n-hexane 14.85
    ethylene glycol 13.13
    NMP 447.29
    cyclohexane 43.79
    DMSO 727.08
    n-butyl acetate 248.49
    n-octanol 66.69
    chloroform 329.13
    n-propyl acetate 270.32
    acetic acid 147.27
    dichloromethane 339.16
    cyclohexanone 524.57
    propylene glycol 41.66
    isopropyl acetate 188.07
    DMAc 400.78
    2-ethoxyethanol 230.85
    isopentanol 176.64
    n-heptane 13.63
    ethyl formate 120.27
    1,2-dichloroethane 275.71
    n-hexanol 99.72
    2-methoxyethanol 294.08
    isobutyl acetate 180.93
    tetrachloromethane 77.34
    n-pentyl acetate 249.71
    transcutol 743.62
    n-heptanol 72.17
    ethylbenzene 40.24
    MIBK 204.25
    2-propoxyethanol 214.99
    tert-butanol 226.8
    MTBE 185.26
    2-butoxyethanol 199.55
    propionic acid 121.32
    o-xylene 50.95
    formic acid 40.96
    diethyl ether 123.95
    m-xylene 44.05
    p-xylene 60.37
    chlorobenzene 96.01
    dimethyl carbonate 42.49
    n-octane 6.76
    formamide 71.66
    cyclopentanone 519.23
    2-pentanone 221.17
    anisole 99.89
    cyclopentyl methyl ether 254.2
    gamma-butyrolactone 483.49
    1-methoxy-2-propanol 263.18
    pyridine 191.18
    3-pentanone 142.21
    furfural 362.19
    n-dodecane 4.42
    diethylene glycol 113.67
    diisopropyl ether 54.1
    tert-amyl alcohol 182.76
    acetylacetone 256.69
    n-hexadecane 5.31
    acetophenone 150.82
    methyl propionate 127.32
    isopentyl acetate 235.45
    trichloroethylene 423.34
    n-nonanol 63.4
    cyclohexanol 202.1
    benzyl alcohol 94.13
    2-ethylhexanol 85.33
    isooctanol 76.03
    dipropyl ether 132.07
    1,2-dichlorobenzene 124.5
    ethyl lactate 105.67
    propylene carbonate 277.91
    n-methylformamide 136.95
    2-pentanol 107.14
    n-pentane 9.34
    1-propoxy-2-propanol 209.0
    1-methoxy-2-propyl acetate 205.64
    2-(2-methoxypropoxy) propanol 146.78
    mesitylene 37.59
    ε-caprolactone 420.36
    p-cymene 39.97
    epichlorohydrin 441.94
    1,1,1-trichloroethane 237.93
    2-aminoethanol 58.03
    morpholine-4-carbaldehyde 351.33
    sulfolane 794.97
    2,2,4-trimethylpentane 11.68
    2-methyltetrahydrofuran 358.79
    n-hexyl acetate 220.91
    isooctane 7.14
    2-(2-butoxyethoxy)ethanol 230.31
    sec-butyl acetate 182.54
    tert-butyl acetate 239.76
    decalin 19.23
    glycerin 71.36
    diglyme 485.31
    acrylic acid 79.67
    isopropyl myristate 65.92
    n-butyric acid 302.12
    acetyl acetate 118.33
    di(2-ethylhexyl) phthalate 65.94
    ethyl propionate 184.4
    nitromethane 262.54
    1,2-diethoxyethane 244.7
    benzonitrile 128.32
    trioctyl phosphate 52.73
    1-bromopropane 154.52
    gamma-valerolactone 659.98
    n-decanol 40.97
    triethyl phosphate 97.98
    4-methyl-2-pentanol 78.92
    propionitrile 88.87
    vinylene carbonate 201.57
    1,1,2-trichlorotrifluoroethane 363.52
    DMS 110.94
    cumene 36.29
    2-octanol 58.54
    2-hexanone 226.39
    octyl acetate 85.02
    limonene 73.07
    1,2-dimethoxyethane 429.03
    ethyl orthosilicate 99.77
    tributyl phosphate 71.69
    diacetone alcohol 263.68
    N,N-dimethylaniline 78.77
    acrylonitrile 95.05
    aniline 75.35
    1,3-propanediol 127.6
    bromobenzene 102.91
    dibromomethane 227.89
    1,1,2,2-tetrachloroethane 442.41
    2-methyl-cyclohexyl acetate 161.46
    tetrabutyl urea 102.4
    diisobutyl methanol 59.97
    2-phenylethanol 90.24
    styrene 50.68
    dioctyl adipate 119.32
    dimethyl sulfate 118.56
    ethyl butyrate 203.58
    methyl lactate 84.32
    butyl lactate 183.79
    diethyl carbonate 111.28
    propanediol butyl ether 165.88
    triethyl orthoformate 151.64
    p-tert-butyltoluene 38.65
    methyl 4-tert-butylbenzoate 158.59
    morpholine 343.1
    tert-butylamine 122.51
    n-dodecanol 28.75
    dimethoxymethane 172.08
    ethylene carbonate 191.17
    cyrene 161.86
    2-ethoxyethyl acetate 259.69
    2-ethylhexyl acetate 179.96
    1,2,4-trichlorobenzene 142.28
    4-methylpyridine 183.06
    dibutyl ether 134.08
    2,6-dimethyl-4-heptanol 59.97
    DEF 291.59
    dimethyl isosorbide 279.34
    tetrachloroethylene 299.3
    eugenol 139.95
    triacetin 224.41
    span 80 143.78
    1,4-butanediol 50.08
    1,1-dichloroethane 208.35
    2-methyl-1-pentanol 119.45
    methyl formate 79.63
    2-methyl-1-butanol 140.25
    n-decane 9.81
    butyronitrile 132.76
    3,7-dimethyl-1-octanol 72.72
    1-chlorooctane 55.7
    1-chlorotetradecane 16.16
    n-nonane 9.29
    undecane 6.07
    tert-butylcyclohexane 16.29
    cyclooctane 10.17
    cyclopentanol 207.04
    tetrahydropyran 328.5
    tert-amyl methyl ether 144.63
    2,5,8-trioxanonane 275.72
    1-hexene 58.58
    2-isopropoxyethanol 179.48
    2,2,2-trifluoroethanol 60.72
    methyl butyrate 309.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction