N-Methyl-N-vinylacetamide

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  • Identifiers

    CAS number
    3195-78-6

    Molecular formula
    C5H9NO

    SMILES
    CC(=O)N(C)C=C

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Pungent 40.58%
    Odorless 26.96%
    Green 25.41%
    Cheesy 23.94%
    Roasted 23.3%
    Burnt 23.25%
    Fishy 22.57%
    Radish 22.02%
    Earthy 21.33%
    Metallic 20.83%

     

    Flavor
    Cooked 25.74%
    Fruity 25.39%
    Pungent 24.15%
    Nutty 23.42%
    Onion 23.16%
    Roasted 22.9%
    Mustard 22.1%
    Matches 21.25%
    Mousy 20.55%
    Acrid 20.52%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.2

    pKa est.
    6.44 (neutral)

    Molecular weight
    99.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    172°C

    Flash point

    • 46.32 ˚C est.

  • Synonyms

    • N-Methyl-N-vinylacetamide
    • 3195-78-6
    • N-Vinyl-N-methylacetamide
    • N-Ethenyl-N-methylacetamide
    • ACETAMIDE, N-METHYL-N-VINYL-
    • N-Vinylmethylacetamide
    • N-Methylvinylacetamide
    • GL7LDW4PGB
    • UNII-GL7LDW4PGB
    • BRN 1743331
    • EINECS 221-698-5
    • DTXSID4052003
    • 3-04-00-00442 (Beilstein Handbook Reference)
    • RefChem:7902
    • DTXCID2030566
    • 221-698-5
    • Acetamide, N-ethenyl-N-methyl-
    • N-Methyl-N-vinyl-acetamide
    • MFCD00008687
    • n-methyl-n-vinyl acetamide
    • N-vinyl-N-methyl acetamide
    • Acetamide, N-methyl-N-vinyl- (6CI,7CI,8CI); N-Ethenyl-N-methylacetamide; N-Vinyl-N-methylacetamide
    • SCHEMBL35307
    • N-Ethenyl-N-methyl-acetamide
    • PNLUGRYDUHRLOF-UHFFFAOYSA-
    • N-Methyl-N-vinylacetamide, 98%
    • MSK158327
    • AKOS015898951
    • FM25912
    • SY107327
    • DB-030203
    • A5757
    • NS00022046
    • D78236
    • EN300-7580049
    • F235676
    • Q27279162
    • N-Methyl-N-vinylacetamide 100 microg/mL in Acetonitrile
    • InChI=1/C5H9NO/c1-4-6(3)5(2)7/h4H,1H2,2-3H3
    • 3195-78-6

  • Applications

    N-Methyl-N-vinylacetamide (CAS number: 3195-78-6) is primarily used as a vinyl monomer in polymer synthesis, enabling the introduction of polar amide functionality into copolymers and hydrogel networks. It is commonly evaluated for applications in water-treatment polymers and as a flocculation and viscosity-modifying agent, leveraging its hydrophilicity and hydrogen-bonding capacity. It can be copolymerized with other vinyl monomers to form specialty coatings and inks with enhanced adhesion and moisture resistance, and serves as an intermediate or comonomer in adhesive formulations to adjust tack and film-forming properties. The compound may also be used to produce hydrogels for biomedical or agricultural applications requiring controlled swelling. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 323.23
    methanol 522.96
    isopropanol 221.8
    water 79.65
    ethyl acetate 74.72
    n-propanol 232.29
    acetone 126.1
    n-butanol 181.41
    acetonitrile 175.78
    DMF 280.72
    toluene 51.66
    isobutanol 167.93
    1,4-dioxane 149.26
    methyl acetate 107.19
    THF 191.52
    2-butanone 128.79
    n-pentanol 110.65
    sec-butanol 204.1
    n-hexane 17.68
    ethylene glycol 87.44
    NMP 308.25
    cyclohexane 16.04
    DMSO 179.31
    n-butyl acetate 29.07
    n-octanol 28.67
    chloroform 255.48
    n-propyl acetate 27.69
    acetic acid 211.99
    dichloromethane 264.67
    cyclohexanone 133.38
    propylene glycol 92.16
    isopropyl acetate 35.75
    DMAc 313.24
    2-ethoxyethanol 135.61
    isopentanol 113.6
    n-heptane 7.04
    ethyl formate 82.01
    1,2-dichloroethane 126.18
    n-hexanol 59.18
    2-methoxyethanol 276.98
    isobutyl acetate 18.44
    tetrachloromethane 62.66
    n-pentyl acetate 29.34
    transcutol 194.63
    n-heptanol 28.78
    ethylbenzene 23.13
    MIBK 36.66
    2-propoxyethanol 93.97
    tert-butanol 187.11
    MTBE 100.71
    2-butoxyethanol 53.33
    propionic acid 141.85
    o-xylene 46.68
    formic acid 208.75
    diethyl ether 101.35
    m-xylene 32.44
    p-xylene 36.69
    chlorobenzene 69.76
    dimethyl carbonate 20.49
    n-octane 3.39
    formamide 239.6
    cyclopentanone 153.78
    2-pentanone 76.9
    anisole 52.5
    cyclopentyl methyl ether 86.0
    gamma-butyrolactone 162.76
    1-methoxy-2-propanol 156.35
    pyridine 158.9
    3-pentanone 70.61
    furfural 188.67
    n-dodecane 2.74
    diethylene glycol 81.29
    diisopropyl ether 17.59
    tert-amyl alcohol 180.66
    acetylacetone 56.83
    n-hexadecane 2.95
    acetophenone 51.07
    methyl propionate 67.83
    isopentyl acetate 29.34
    trichloroethylene 205.12
    n-nonanol 26.9
    cyclohexanol 112.62
    benzyl alcohol 65.25
    2-ethylhexanol 31.17
    isooctanol 23.9
    dipropyl ether 25.0
    1,2-dichlorobenzene 60.23
    ethyl lactate 22.69
    propylene carbonate 71.12
    n-methylformamide 194.69
    2-pentanol 96.51
    n-pentane 20.9
    1-propoxy-2-propanol 52.59
    1-methoxy-2-propyl acetate 34.0
    2-(2-methoxypropoxy) propanol 56.35
    mesitylene 17.63
    ε-caprolactone 112.26
    p-cymene 14.69
    epichlorohydrin 176.4
    1,1,1-trichloroethane 122.18
    2-aminoethanol 182.29
    morpholine-4-carbaldehyde 211.96
    sulfolane 165.81
    2,2,4-trimethylpentane 10.81
    2-methyltetrahydrofuran 181.93
    n-hexyl acetate 40.39
    isooctane 4.15
    2-(2-butoxyethoxy)ethanol 70.02
    sec-butyl acetate 21.66
    tert-butyl acetate 34.49
    decalin 8.66
    glycerin 115.48
    diglyme 107.24
    acrylic acid 116.01
    isopropyl myristate 15.91
    n-butyric acid 133.06
    acetyl acetate 36.9
    di(2-ethylhexyl) phthalate 22.81
    ethyl propionate 31.32
    nitromethane 235.34
    1,2-diethoxyethane 52.35
    benzonitrile 75.07
    trioctyl phosphate 13.59
    1-bromopropane 97.29
    gamma-valerolactone 191.44
    n-decanol 19.07
    triethyl phosphate 18.54
    4-methyl-2-pentanol 38.25
    propionitrile 129.21
    vinylene carbonate 72.91
    1,1,2-trichlorotrifluoroethane 138.04
    DMS 31.84
    cumene 18.54
    2-octanol 21.74
    2-hexanone 42.25
    octyl acetate 21.41
    limonene 22.27
    1,2-dimethoxyethane 140.8
    ethyl orthosilicate 19.13
    tributyl phosphate 17.86
    diacetone alcohol 58.9
    N,N-dimethylaniline 45.07
    acrylonitrile 141.27
    aniline 103.59
    1,3-propanediol 186.5
    bromobenzene 57.79
    dibromomethane 168.4
    1,1,2,2-tetrachloroethane 157.39
    2-methyl-cyclohexyl acetate 28.55
    tetrabutyl urea 25.75
    diisobutyl methanol 15.74
    2-phenylethanol 44.24
    styrene 30.35
    dioctyl adipate 24.82
    dimethyl sulfate 41.46
    ethyl butyrate 25.75
    methyl lactate 44.09
    butyl lactate 26.74
    diethyl carbonate 17.61
    propanediol butyl ether 46.0
    triethyl orthoformate 22.3
    p-tert-butyltoluene 13.64
    methyl 4-tert-butylbenzoate 44.09
    morpholine 219.05
    tert-butylamine 123.34
    n-dodecanol 14.05
    dimethoxymethane 89.62
    ethylene carbonate 54.28
    cyrene 60.84
    2-ethoxyethyl acetate 41.02
    2-ethylhexyl acetate 23.99
    1,2,4-trichlorobenzene 79.71
    4-methylpyridine 160.1
    dibutyl ether 27.72
    2,6-dimethyl-4-heptanol 15.74
    DEF 118.99
    dimethyl isosorbide 80.7
    tetrachloroethylene 122.18
    eugenol 46.64
    triacetin 37.88
    span 80 45.11
    1,4-butanediol 69.36
    1,1-dichloroethane 147.45
    2-methyl-1-pentanol 88.77
    methyl formate 99.01
    2-methyl-1-butanol 145.94
    n-decane 4.68
    butyronitrile 120.5
    3,7-dimethyl-1-octanol 28.41
    1-chlorooctane 17.16
    1-chlorotetradecane 7.09
    n-nonane 4.42
    undecane 3.45
    tert-butylcyclohexane 8.79
    cyclooctane 4.65
    cyclopentanol 140.73
    tetrahydropyran 130.31
    tert-amyl methyl ether 88.54
    2,5,8-trioxanonane 85.24
    1-hexene 46.04
    2-isopropoxyethanol 71.37
    2,2,2-trifluoroethanol 90.33
    methyl butyrate 46.21

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction