N-Lactoyl tyramine, (+-)-

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  • Identifiers

    CAS number
    781674-18-8

    Molecular formula
    C11H15NO3

    SMILES
    CC(C(=O)NCCC1=CC=C(C=C1)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 48.91%
    Savory 40.97%
    Meaty 35.16%
    Sweet 27.27%
    Milky 24.76%
    Cooked 23.15%
    Cooling 23.02%
    Bitter 22.88%
    Roasted 20.86%
    Fishy 20.43%

     

    Flavor
    Odorless 55.0%
    Mild 39.19%
    Fruity 32.78%
    Bitter 29.43%
    Bland 23.68%
    Sweet-like 22.4%
    Sweet 21.49%
    Orange flower 20.41%
    Very mild 20.23%
    Orange blossom 19.5%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.9

    pKa est.
    8.87 (weak base)

    Molecular weight
    209.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    431°C

    Flash point

    • 205.05 ˚C est.

  • Synonyms

    • FEMA no. 4550
    • 2-Hydroxy-N-(4-hydroxyphenethyl)propanamide
    • DU72SR0368
    • Propanamide, 2-hydroxy-N-(2-(4-hydroxyphenyl)ethyl)-
    • N-LACTOYLTYRAMINE
    • RefChem:830204
    • N-Lactoyl tyramine, (+-)-
    • (+-)-N-LACTOYL TYRAMINE
    • (+/-)-N-lactoyl tyramine
    • N-Lactoyl tyramine, (+/-)-
    • UNII-DU72SR0368
    • 781674-18-8
    • SCHEMBL5060920
    • DTXSID10999411
    • NS00125593
    • 2-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanamide
    • Q27276607
    • 2-Hydroxy-N-[2-(4-hydroxyphenyl)ethyl]propanimidic acid
    • 781674-18-8

  • Applications

    N-Lactoyl tyramine, (+-), CAS 781674-18-8, is a biologically derived amide that can be used as a synthetic intermediate and a starting point for organic synthesis, and is evaluated as a fragrance ingredient or precursor for fragrance-related compounds; in perfumery it may be used as a fragrance intermediate or odorant precursor; in cosmetics and personal care it may be considered as a conjugated component or formulation-building block for product development; in medicinal chemistry it is commonly evaluated as an intermediate for library generation and downstream transformations; in plant science and agriculture it is observed as a biosynthetic metabolite or biomarker associated with stress responses and is studied in that context; and in materials science it can be explored as a building block for bio-based polymers or related materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 36.27
    methanol 141.35
    isopropanol 15.89
    water 14.4
    ethyl acetate 12.03
    n-propanol 21.97
    acetone 13.29
    n-butanol 16.0
    acetonitrile 3.4
    DMF 169.97
    toluene 1.23
    isobutanol 12.14
    1,4-dioxane 22.73
    methyl acetate 8.54
    THF 48.01
    2-butanone 10.31
    n-pentanol 10.94
    sec-butanol 14.47
    n-hexane 0.24
    ethylene glycol 90.73
    NMP 55.29
    cyclohexane 0.24
    DMSO 336.54
    n-butyl acetate 5.53
    n-octanol 4.13
    chloroform 3.0
    n-propyl acetate 5.89
    acetic acid 142.31
    dichloromethane 2.47
    cyclohexanone 20.69
    propylene glycol 71.06
    isopropyl acetate 8.27
    DMAc 244.05
    2-ethoxyethanol 115.39
    isopentanol 18.38
    n-heptane 0.3
    ethyl formate 11.42
    1,2-dichloroethane 3.15
    n-hexanol 11.92
    2-methoxyethanol 188.79
    isobutyl acetate 4.11
    tetrachloromethane 1.26
    n-pentyl acetate 4.24
    transcutol 202.83
    n-heptanol 6.68
    ethylbenzene 1.28
    MIBK 12.04
    2-propoxyethanol 51.98
    tert-butanol 48.79
    MTBE 12.08
    2-butoxyethanol 25.69
    propionic acid 38.78
    o-xylene 2.43
    formic acid 294.7
    diethyl ether 4.13
    m-xylene 2.01
    p-xylene 1.68
    chlorobenzene 1.71
    dimethyl carbonate 12.86
    n-octane 0.21
    formamide 357.85
    cyclopentanone 27.83
    2-pentanone 10.5
    anisole 7.7
    cyclopentyl methyl ether 10.57
    gamma-butyrolactone 39.07
    1-methoxy-2-propanol 84.13
    pyridine 8.33
    3-pentanone 6.68
    furfural 51.91
    n-dodecane 0.18
    diethylene glycol 101.8
    diisopropyl ether 2.24
    tert-amyl alcohol 35.71
    acetylacetone 27.0
    n-hexadecane 0.2
    acetophenone 11.06
    methyl propionate 12.84
    isopentyl acetate 8.08
    trichloroethylene 9.03
    n-nonanol 4.58
    cyclohexanol 11.31
    benzyl alcohol 13.8
    2-ethylhexanol 5.63
    isooctanol 6.09
    dipropyl ether 3.6
    1,2-dichlorobenzene 2.95
    ethyl lactate 15.12
    propylene carbonate 19.0
    n-methylformamide 81.64
    2-pentanol 8.38
    n-pentane 0.18
    1-propoxy-2-propanol 28.18
    1-methoxy-2-propyl acetate 19.47
    2-(2-methoxypropoxy) propanol 39.23
    mesitylene 1.84
    ε-caprolactone 20.56
    p-cymene 1.9
    epichlorohydrin 28.81
    1,1,1-trichloroethane 2.69
    2-aminoethanol 118.23
    morpholine-4-carbaldehyde 86.99
    sulfolane 82.46
    2,2,4-trimethylpentane 0.41
    2-methyltetrahydrofuran 15.31
    n-hexyl acetate 6.59
    isooctane 0.28
    2-(2-butoxyethoxy)ethanol 52.79
    sec-butyl acetate 4.86
    tert-butyl acetate 15.57
    decalin 0.35
    glycerin 169.71
    diglyme 83.9
    acrylic acid 47.2
    isopropyl myristate 3.44
    n-butyric acid 34.89
    acetyl acetate 10.1
    di(2-ethylhexyl) phthalate 7.75
    ethyl propionate 6.14
    nitromethane 126.68
    1,2-diethoxyethane 15.3
    benzonitrile 5.41
    trioctyl phosphate 5.13
    1-bromopropane 1.04
    gamma-valerolactone 60.21
    n-decanol 3.58
    triethyl phosphate 7.02
    4-methyl-2-pentanol 8.27
    propionitrile 3.45
    vinylene carbonate 15.68
    1,1,2-trichlorotrifluoroethane 75.46
    DMS 10.17
    cumene 1.55
    2-octanol 3.54
    2-hexanone 6.66
    octyl acetate 4.81
    limonene 2.64
    1,2-dimethoxyethane 79.25
    ethyl orthosilicate 6.61
    tributyl phosphate 6.11
    diacetone alcohol 46.16
    N,N-dimethylaniline 8.36
    acrylonitrile 7.57
    aniline 7.28
    1,3-propanediol 112.85
    bromobenzene 1.11
    dibromomethane 1.43
    1,1,2,2-tetrachloroethane 9.14
    2-methyl-cyclohexyl acetate 8.37
    tetrabutyl urea 9.37
    diisobutyl methanol 4.81
    2-phenylethanol 11.75
    styrene 1.22
    dioctyl adipate 7.67
    dimethyl sulfate 37.59
    ethyl butyrate 5.86
    methyl lactate 32.71
    butyl lactate 11.99
    diethyl carbonate 5.2
    propanediol butyl ether 32.8
    triethyl orthoformate 7.04
    p-tert-butyltoluene 2.1
    methyl 4-tert-butylbenzoate 17.92
    morpholine 37.81
    tert-butylamine 11.72
    n-dodecanol 2.78
    dimethoxymethane 52.47
    ethylene carbonate 12.25
    cyrene 37.48
    2-ethoxyethyl acetate 12.54
    2-ethylhexyl acetate 4.83
    1,2,4-trichlorobenzene 4.44
    4-methylpyridine 7.09
    dibutyl ether 2.83
    2,6-dimethyl-4-heptanol 4.81
    DEF 27.39
    dimethyl isosorbide 46.5
    tetrachloroethylene 8.71
    eugenol 21.65
    triacetin 15.88
    span 80 24.87
    1,4-butanediol 48.81
    1,1-dichloroethane 1.45
    2-methyl-1-pentanol 14.04
    methyl formate 45.55
    2-methyl-1-butanol 15.93
    n-decane 0.27
    butyronitrile 3.87
    3,7-dimethyl-1-octanol 6.14
    1-chlorooctane 1.07
    1-chlorotetradecane 0.59
    n-nonane 0.23
    undecane 0.21
    tert-butylcyclohexane 0.39
    cyclooctane 0.18
    cyclopentanol 13.44
    tetrahydropyran 7.49
    tert-amyl methyl ether 11.56
    2,5,8-trioxanonane 66.05
    1-hexene 0.85
    2-isopropoxyethanol 49.29
    2,2,2-trifluoroethanol 55.86
    methyl butyrate 9.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction