N-ethyl-2-pyrrolidone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    2687-91-4

    Molecular formula
    C6H11NO

    SMILES
    CCN1CCCC1=O

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Nutty 45.85%
    Roasted 38.92%
    Popcorn 35.91%
    Burnt 34.74%
    Fishy 33.31%
    Caramellic 30.81%
    Sweet 30.1%
    Musty 23.95%
    Spicy 22.51%
    Mint 22.08%

     

    Flavor
    Bitter 31.78%
    Minty 27.02%
    Roasted 26.05%
    Leaves 21.33%
    Others 21.27%
    Fenugreek 21.05%
    Alkaline 20.98%
    Lovage 20.94%
    Shrimp 20.92%
    Cauliflower 20.77%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    7.63 (neutral)

    Molecular weight
    113.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    209°C

    Flash point

    • 79.94 ˚C est.

  • Synonyms

    • 2687-91-4
    • 1-ETHYL-2-PYRROLIDINONE
    • N-Ethyl-2-pyrrolidone
    • Ethyl pyrrolidone
    • DTXSID3044413
    • H0229SX1CW
    • DTXCID1024413
    • RefChem:596395
    • 220-250-6
    • 1-Ethylpyrrolidin-2-one
    • 1-Ethyl-2-pyrrolidone
    • N-Ethylpyrrolidone
    • Pyrrolidinone, 1-ethyl-
    • 2-Pyrrolidinone, 1-ethyl-
    • N-Ethylpyrrolidinone
    • n-ethyl-2-pyrrolidinone
    • MFCD00003199
    • NCGC00160611-01
    • CAS-2687-91-4
    • BRN 0107971
    • EINECS 220-250-6
    • UNII-H0229SX1CW
    • n-ethyl-pyrrolidone
    • Agsol Ex 2
    • N-Ethyl-2-azapentanone
    • Ethyl-pyrrolidone (NEP)
    • N-ETHYLBUTYROLACTAM
    • 1-Ethyl-pyrrolidin-2-one
    • EC 220-250-6
    • SCHEMBL18635
    • 5-21-06-00328 (Beilstein Handbook Reference)
    • MLS004734624
    • CHEMBL12221
    • SCHEMBL510427
    • SCHEMBL649628
    • orb3030435
    • SCHEMBL1199960
    • SCHEMBL3239145
    • 1-Ethyl-2-pyrrolidone, 98%
    • SCHEMBL17294453
    • SCHEMBL28956340
    • 1-ethyl-2-pyrrolidinone, 98%
    • ETHYLAZACYCLOPENTAN-2-ONE
    • CHEBI:173690
    • Tox21_111935
    • Tox21_302140
    • EBC-50116
    • N-ETHYL-.GAMMA.-BUTYROLACTAM
    • N-ETHYL-.ALPHA.-PYRROLIDINONE
    • AKOS015915384
    • MSK14924-100M
    • Tox21_111935_1
    • CS-W013650
    • MSK14924-1000M
    • NCGC00160611-02
    • NCGC00160611-03
    • NCGC00255747-01
    • AS-12228
    • SMR001561581
    • DB-047038
    • DB-371554
    • E0358
    • NS00003410
    • A10865
    • SBI-0653916.0001
    • EN300-7375258
    • F492381
    • BRD-K08288352-001-03-6
    • N-Ethyl-2-pyrrolidone Solution in Methanol, 100ug/mL
    • Q27279388
    • N-Ethyl-2-pyrrolidone Solution in Methanol, 1000ug/mL
    • Z1255438420
    • InChI=1/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H
    • 2-pyrrolidinone, 1-ethyl-;1-ethylpyrrolidin-2-one;2-pyrrolidinone, 1-ethyl- 1-ethylpyrrolidin-2-one
    • 2687-91-4

  • Applications

    N-ethyl-2-pyrrolidone (CAS 2687-91-4) is a polar aprotic solvent widely used as a processing solvent for coatings, inks, and adhesives, and for polymer processing such as polyurethanes and acrylic resins. It is employed as a cleaning and surface-preparation solvent in industrial manufacturing, particularly for electronics and semiconductor applications involving surface cleaning and residue removal. NEP is also used as a solvent and processing aid in the production of specialty polymers and composites, and can serve as an intermediate in the synthesis of specialty chemicals.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1508.75
    methanol 3074.59
    isopropanol 761.26
    water 127.4
    ethyl acetate 359.6
    n-propanol 912.57
    acetone 607.84
    n-butanol 673.44
    acetonitrile 979.85
    DMF 818.74
    toluene 216.37
    isobutanol 590.49
    1,4-dioxane 571.66
    methyl acetate 390.7
    THF 770.97
    2-butanone 444.77
    n-pentanol 464.45
    sec-butanol 569.27
    n-hexane 32.67
    ethylene glycol 426.29
    NMP 824.53
    cyclohexane 40.18
    DMSO 833.4
    n-butyl acetate 234.04
    n-octanol 124.7
    chloroform 2454.73
    n-propyl acetate 188.39
    acetic acid 2155.37
    dichloromethane 2333.86
    cyclohexanone 580.1
    propylene glycol 335.99
    isopropyl acetate 196.26
    DMAc 523.42
    2-ethoxyethanol 618.11
    isopentanol 469.81
    n-heptane 17.07
    ethyl formate 432.64
    1,2-dichloroethane 756.31
    n-hexanol 273.17
    2-methoxyethanol 1031.01
    isobutyl acetate 119.92
    tetrachloromethane 356.83
    n-pentyl acetate 181.19
    transcutol 1056.14
    n-heptanol 134.07
    ethylbenzene 89.09
    MIBK 174.94
    2-propoxyethanol 453.7
    tert-butanol 515.49
    MTBE 295.09
    2-butoxyethanol 273.03
    propionic acid 794.35
    o-xylene 130.39
    formic acid 1633.97
    diethyl ether 319.31
    m-xylene 124.98
    p-xylene 136.48
    chlorobenzene 508.52
    dimethyl carbonate 95.66
    n-octane 8.47
    formamide 1349.51
    cyclopentanone 716.62
    2-pentanone 301.34
    anisole 215.33
    cyclopentyl methyl ether 301.96
    gamma-butyrolactone 903.94
    1-methoxy-2-propanol 503.88
    pyridine 852.97
    3-pentanone 212.97
    furfural 1028.12
    n-dodecane 8.54
    diethylene glycol 433.06
    diisopropyl ether 71.85
    tert-amyl alcohol 440.86
    acetylacetone 294.09
    n-hexadecane 9.55
    acetophenone 210.04
    methyl propionate 258.77
    isopentyl acetate 191.54
    trichloroethylene 1658.02
    n-nonanol 104.44
    cyclohexanol 378.52
    benzyl alcohol 308.91
    2-ethylhexanol 128.4
    isooctanol 110.27
    dipropyl ether 97.88
    1,2-dichlorobenzene 399.52
    ethyl lactate 110.79
    propylene carbonate 418.98
    n-methylformamide 889.92
    2-pentanol 332.58
    n-pentane 42.47
    1-propoxy-2-propanol 245.23
    1-methoxy-2-propyl acetate 181.23
    2-(2-methoxypropoxy) propanol 197.68
    mesitylene 72.1
    ε-caprolactone 510.37
    p-cymene 61.72
    epichlorohydrin 873.26
    1,1,1-trichloroethane 718.1
    2-aminoethanol 755.62
    morpholine-4-carbaldehyde 622.5
    sulfolane 743.96
    2,2,4-trimethylpentane 26.6
    2-methyltetrahydrofuran 619.93
    n-hexyl acetate 226.5
    isooctane 16.13
    2-(2-butoxyethoxy)ethanol 299.25
    sec-butyl acetate 121.08
    tert-butyl acetate 168.65
    decalin 23.8
    glycerin 424.91
    diglyme 486.92
    acrylic acid 820.75
    isopropyl myristate 68.77
    n-butyric acid 834.97
    acetyl acetate 272.95
    di(2-ethylhexyl) phthalate 100.06
    ethyl propionate 141.87
    nitromethane 1515.78
    1,2-diethoxyethane 253.02
    benzonitrile 514.6
    trioctyl phosphate 59.46
    1-bromopropane 452.62
    gamma-valerolactone 775.2
    n-decanol 71.18
    triethyl phosphate 75.39
    4-methyl-2-pentanol 164.63
    propionitrile 607.63
    vinylene carbonate 464.02
    1,1,2-trichlorotrifluoroethane 671.64
    DMS 162.82
    cumene 70.76
    2-octanol 89.72
    2-hexanone 195.6
    octyl acetate 94.57
    limonene 86.51
    1,2-dimethoxyethane 478.42
    ethyl orthosilicate 71.33
    tributyl phosphate 81.85
    diacetone alcohol 215.5
    N,N-dimethylaniline 144.91
    acrylonitrile 806.91
    aniline 445.49
    1,3-propanediol 780.93
    bromobenzene 473.61
    dibromomethane 1264.11
    1,1,2,2-tetrachloroethane 987.58
    2-methyl-cyclohexyl acetate 121.89
    tetrabutyl urea 97.56
    diisobutyl methanol 67.12
    2-phenylethanol 227.25
    styrene 137.87
    dioctyl adipate 108.22
    dimethyl sulfate 164.27
    ethyl butyrate 141.05
    methyl lactate 155.27
    butyl lactate 138.61
    diethyl carbonate 99.09
    propanediol butyl ether 236.98
    triethyl orthoformate 98.45
    p-tert-butyltoluene 55.52
    methyl 4-tert-butylbenzoate 167.1
    morpholine 707.05
    tert-butylamine 341.93
    n-dodecanol 50.6
    dimethoxymethane 333.72
    ethylene carbonate 339.45
    cyrene 199.66
    2-ethoxyethyl acetate 244.95
    2-ethylhexyl acetate 145.19
    1,2,4-trichlorobenzene 472.17
    4-methylpyridine 741.08
    dibutyl ether 111.39
    2,6-dimethyl-4-heptanol 67.12
    DEF 353.68
    dimethyl isosorbide 282.44
    tetrachloroethylene 788.41
    eugenol 198.71
    triacetin 187.41
    span 80 184.51
    1,4-butanediol 356.17
    1,1-dichloroethane 892.32
    2-methyl-1-pentanol 346.5
    methyl formate 518.75
    2-methyl-1-butanol 490.15
    n-decane 14.31
    butyronitrile 588.12
    3,7-dimethyl-1-octanol 122.52
    1-chlorooctane 67.69
    1-chlorotetradecane 25.25
    n-nonane 13.26
    undecane 10.65
    tert-butylcyclohexane 24.42
    cyclooctane 12.26
    cyclopentanol 526.08
    tetrahydropyran 460.45
    tert-amyl methyl ether 207.17
    2,5,8-trioxanonane 313.49
    1-hexene 131.21
    2-isopropoxyethanol 336.71
    2,2,2-trifluoroethanol 601.44
    methyl butyrate 221.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction