N-Cyclohexanoyl tyramine

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  • Identifiers

    CAS number
    727732-91-4

    Molecular formula
    C15H21NO2

    SMILES
    C1CCC(CC1)C(=O)NCCC2=CC=C(C=C2)O

    Safety labels

  • Odor profile

    Fragrance
    Meaty 39.03%
    Savory 37.84%
    Cooling 37.03%
    Odorless 33.51%
    Animal 30.4%
    Cheesy 28.52%
    Fishy 26.33%
    Roasted 25.69%
    Mint 25.14%
    Spicy 24.67%

     

    Flavor
    Odorless 33.56%
    Mild 32.46%
    Fruity 31.79%
    Bitter 29.23%
    Sweet 22.95%
    Animal 21.64%
    Orange blossom 20.91%
    Herbal 20.8%
    Orange flower 20.66%
    Petitgrain 20.65%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    9.21 (weak base)

    Molecular weight
    247.33 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    434°C

    Flash point

    • 193.29 ˚C est.

  • Synonyms

    • N-Cyclohexanoyl tyramine
    • Actowhite CT247
    • UNII-NW9L0542MA
    • NW9L0542MA
    • N-Cyclohexanoyl tyramine [INCI]
    • Cyclohexanecarboxamide, N-(2-(4-hydroxyphenyl)ethyl)-
    • 727732-91-4
    • AKOS005811803
    • Q27285073
    • 727732-91-4

  • Applications

    N-Cyclohexanoyl tyramine (CAS 727732-91-4) is primarily regarded as a fragrance-related intermediate and odorant component, serving as a building block for tyramine-derived aroma compounds in perfumery. It may be used in cosmetics and personal care formulations as a fragrance ingredient or scent booster, and can function as an industrial synthesis intermediate for developing organic compounds. Additionally, it has potential as a functionalized amide for polymer or plastics-related applications, or as a component in coatings and cleaning products where controlled aroma is desirable, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 71.19
    methanol 142.02
    isopropanol 41.82
    water 0.08
    ethyl acetate 61.86
    n-propanol 53.71
    acetone 113.09
    n-butanol 50.46
    acetonitrile 32.8
    DMF 145.05
    toluene 16.69
    isobutanol 27.12
    1,4-dioxane 138.31
    methyl acetate 53.84
    THF 194.28
    2-butanone 86.65
    n-pentanol 34.98
    sec-butanol 26.12
    n-hexane 0.49
    ethylene glycol 9.35
    NMP 63.35
    cyclohexane 0.82
    DMSO 356.07
    n-butyl acetate 50.68
    n-octanol 11.35
    chloroform 153.79
    n-propyl acetate 48.58
    acetic acid 82.87
    dichloromethane 119.6
    cyclohexanone 111.74
    propylene glycol 22.86
    isopropyl acetate 41.84
    DMAc 192.58
    2-ethoxyethanol 93.62
    isopentanol 46.37
    n-heptane 0.58
    ethyl formate 40.93
    1,2-dichloroethane 102.64
    n-hexanol 33.66
    2-methoxyethanol 156.0
    isobutyl acetate 31.42
    tetrachloromethane 7.35
    n-pentyl acetate 27.11
    transcutol 448.11
    n-heptanol 17.84
    ethylbenzene 10.47
    MIBK 46.6
    2-propoxyethanol 95.91
    tert-butanol 51.28
    MTBE 33.11
    2-butoxyethanol 55.57
    propionic acid 46.73
    o-xylene 13.52
    formic acid 37.07
    diethyl ether 29.45
    m-xylene 14.3
    p-xylene 14.05
    chlorobenzene 34.21
    dimethyl carbonate 23.25
    n-octane 0.45
    formamide 72.41
    cyclopentanone 143.29
    2-pentanone 69.01
    anisole 35.12
    cyclopentyl methyl ether 40.76
    gamma-butyrolactone 144.02
    1-methoxy-2-propanol 106.54
    pyridine 86.13
    3-pentanone 42.41
    furfural 131.89
    n-dodecane 0.58
    diethylene glycol 81.83
    diisopropyl ether 7.4
    tert-amyl alcohol 32.46
    acetylacetone 92.57
    n-hexadecane 0.68
    acetophenone 43.35
    methyl propionate 44.97
    isopentyl acetate 47.04
    trichloroethylene 211.82
    n-nonanol 12.9
    cyclohexanol 29.59
    benzyl alcohol 39.55
    2-ethylhexanol 17.83
    isooctanol 16.24
    dipropyl ether 14.33
    1,2-dichlorobenzene 36.15
    ethyl lactate 28.59
    propylene carbonate 69.35
    n-methylformamide 65.75
    2-pentanol 23.1
    n-pentane 0.3
    1-propoxy-2-propanol 59.6
    1-methoxy-2-propyl acetate 62.05
    2-(2-methoxypropoxy) propanol 58.54
    mesitylene 8.8
    ε-caprolactone 82.54
    p-cymene 8.63
    epichlorohydrin 191.35
    1,1,1-trichloroethane 44.51
    2-aminoethanol 33.37
    morpholine-4-carbaldehyde 103.79
    sulfolane 167.74
    2,2,4-trimethylpentane 1.0
    2-methyltetrahydrofuran 65.2
    n-hexyl acetate 32.85
    isooctane 0.84
    2-(2-butoxyethoxy)ethanol 94.58
    sec-butyl acetate 31.42
    tert-butyl acetate 46.56
    decalin 1.39
    glycerin 46.83
    diglyme 177.86
    acrylic acid 41.38
    isopropyl myristate 13.39
    n-butyric acid 81.52
    acetyl acetate 37.61
    di(2-ethylhexyl) phthalate 20.01
    ethyl propionate 33.81
    nitromethane 152.19
    1,2-diethoxyethane 78.67
    benzonitrile 41.31
    trioctyl phosphate 12.8
    1-bromopropane 23.78
    gamma-valerolactone 178.33
    n-decanol 10.02
    triethyl phosphate 20.57
    4-methyl-2-pentanol 19.91
    propionitrile 31.41
    vinylene carbonate 60.45
    1,1,2-trichlorotrifluoroethane 115.3
    DMS 34.33
    cumene 9.01
    2-octanol 9.67
    2-hexanone 49.52
    octyl acetate 17.35
    limonene 11.11
    1,2-dimethoxyethane 140.49
    ethyl orthosilicate 20.04
    tributyl phosphate 16.66
    diacetone alcohol 68.28
    N,N-dimethylaniline 24.48
    acrylonitrile 46.12
    aniline 35.13
    1,3-propanediol 69.14
    bromobenzene 30.0
    dibromomethane 56.98
    1,1,2,2-tetrachloroethane 165.25
    2-methyl-cyclohexyl acetate 31.93
    tetrabutyl urea 22.22
    diisobutyl methanol 12.0
    2-phenylethanol 36.61
    styrene 13.04
    dioctyl adipate 24.47
    dimethyl sulfate 48.57
    ethyl butyrate 34.69
    methyl lactate 36.39
    butyl lactate 34.11
    diethyl carbonate 24.82
    propanediol butyl ether 51.0
    triethyl orthoformate 27.52
    p-tert-butyltoluene 8.21
    methyl 4-tert-butylbenzoate 41.12
    morpholine 145.48
    tert-butylamine 20.34
    n-dodecanol 7.61
    dimethoxymethane 104.97
    ethylene carbonate 51.02
    cyrene 54.66
    2-ethoxyethyl acetate 56.86
    2-ethylhexyl acetate 32.12
    1,2,4-trichlorobenzene 42.69
    4-methylpyridine 59.13
    dibutyl ether 16.0
    2,6-dimethyl-4-heptanol 12.0
    DEF 59.55
    dimethyl isosorbide 89.18
    tetrachloroethylene 87.51
    eugenol 45.77
    triacetin 46.97
    span 80 44.06
    1,4-butanediol 24.6
    1,1-dichloroethane 60.46
    2-methyl-1-pentanol 33.82
    methyl formate 44.78
    2-methyl-1-butanol 31.18
    n-decane 0.89
    butyronitrile 38.72
    3,7-dimethyl-1-octanol 15.81
    1-chlorooctane 5.87
    1-chlorotetradecane 2.7
    n-nonane 0.65
    undecane 0.69
    tert-butylcyclohexane 1.39
    cyclooctane 0.38
    cyclopentanol 28.88
    tetrahydropyran 77.62
    tert-amyl methyl ether 23.05
    2,5,8-trioxanonane 109.75
    1-hexene 4.68
    2-isopropoxyethanol 60.47
    2,2,2-trifluoroethanol 26.37
    methyl butyrate 52.36

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction