N-Carbamoylputrescine

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  • Identifiers

    CAS number
    6851-51-0

    Molecular formula
    C5H13N3O

    SMILES
    C(CCNC(=O)N)CN

    Safety labels

  • Odor profile

    Fragrance
    Fishy 68.5%
    Odorless 51.9%
    Cheesy 40.11%
    Ripe 33.46%
    Meaty 32.09%
    Savory 30.88%
    Animal 25.16%
    Cooling 21.63%
    Pungent 19.17%
    Cooked 17.83%

     

    Flavor
    Odorless 47.19%
    Mild 30.32%
    Sulfury 25.07%
    Faint 23.0%
    Bland 22.44%
    Sulfurous 20.9%
    Fishy 20.32%
    Glue 19.97%
    Sweet-like 19.63%
    Bloody 19.58%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.1

    pKa est.
    6.59 (neutral)

    Molecular weight
    131.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    357°C

    Flash point

    • 145.74 ˚C est.

  • Synonyms

    • N-carbamoylputrescine
    • (4-aminobutyl)urea
    • 6851-51-0
    • 4-aminobutylurea
    • Urea, (4-aminobutyl)-
    • Q40BOH7F84
    • CHEBI:17902
    • DTXSID10218639
    • RefChem:163080
    • DTXCID10141130
    • Urea, N-(4-aminobutyl)-
    • 1-(4-aminobutyl)urea
    • UNII-Q40BOH7F84
    • (4-aminobutyl)-Urea
    • N-(4-Aminobutyl)urea
    • SCHEMBL1332569
    • SCHEMBL7963432
    • AKOS005067098
    • C00436
    • EN300-146691
    • Q3869317
    • 6851-51-0

  • Applications

    N-Carbamoylputrescine (CAS 6851-51-0) is commonly used as an intermediate in organic synthesis, functioning as a protected diamine derivative that can be deprotected to furnish putrescine in multi-step sequences. It also serves as a building block in polymer and materials chemistry, enabling incorporation into polyamine-containing polymers and used as a precursor for crosslinking or functionalization after appropriate modification. The compound is also evaluated in research settings as a precursor for pharmaceutical and agricultural intermediates and as a reference material for polyamine chemistry and related biological processes. Its use is typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.12
    methanol 59.89
    isopropanol 0.8
    water 2312.17
    ethyl acetate 0.54
    n-propanol 2.57
    acetone 1.18
    n-butanol 1.22
    acetonitrile 0.83
    DMF 24.85
    toluene 0.28
    isobutanol 1.66
    1,4-dioxane 0.88
    methyl acetate 0.63
    THF 4.55
    2-butanone 0.64
    n-pentanol 1.06
    sec-butanol 0.83
    n-hexane 0.14
    ethylene glycol 132.52
    NMP 109.87
    cyclohexane 0.17
    DMSO 112.3
    n-butyl acetate 1.58
    n-octanol 0.52
    chloroform 0.83
    n-propyl acetate 0.68
    acetic acid 155.42
    dichloromethane 0.71
    cyclohexanone 4.5
    propylene glycol 59.73
    isopropyl acetate 0.5
    DMAc 26.45
    2-ethoxyethanol 8.29
    isopentanol 1.26
    n-heptane 0.16
    ethyl formate 5.23
    1,2-dichloroethane 0.46
    n-hexanol 2.13
    2-methoxyethanol 25.29
    isobutyl acetate 0.57
    tetrachloromethane 1.16
    n-pentyl acetate 0.83
    transcutol 11.91
    n-heptanol 1.25
    ethylbenzene 0.2
    MIBK 0.7
    2-propoxyethanol 11.6
    tert-butanol 1.82
    MTBE 0.29
    2-butoxyethanol 6.21
    propionic acid 33.08
    o-xylene 0.63
    formic acid 700.2
    diethyl ether 0.11
    m-xylene 0.47
    p-xylene 0.38
    chlorobenzene 0.53
    dimethyl carbonate 2.32
    n-octane 0.05
    formamide 277.79
    cyclopentanone 10.78
    2-pentanone 0.48
    anisole 0.54
    cyclopentyl methyl ether 1.57
    gamma-butyrolactone 25.99
    1-methoxy-2-propanol 7.13
    pyridine 2.05
    3-pentanone 0.61
    furfural 48.29
    n-dodecane 0.03
    diethylene glycol 36.49
    diisopropyl ether 0.12
    tert-amyl alcohol 2.34
    acetylacetone 2.34
    n-hexadecane 0.03
    acetophenone 1.86
    methyl propionate 1.14
    isopentyl acetate 1.79
    trichloroethylene 1.4
    n-nonanol 0.51
    cyclohexanol 2.09
    benzyl alcohol 2.39
    2-ethylhexanol 1.28
    isooctanol 1.03
    dipropyl ether 0.51
    1,2-dichlorobenzene 0.89
    ethyl lactate 4.58
    propylene carbonate 16.11
    n-methylformamide 38.06
    2-pentanol 0.41
    n-pentane 0.07
    1-propoxy-2-propanol 5.71
    1-methoxy-2-propyl acetate 3.47
    2-(2-methoxypropoxy) propanol 7.19
    mesitylene 0.48
    ε-caprolactone 6.46
    p-cymene 0.57
    epichlorohydrin 3.71
    1,1,1-trichloroethane 0.53
    2-aminoethanol 85.82
    morpholine-4-carbaldehyde 33.22
    sulfolane 97.28
    2,2,4-trimethylpentane 0.11
    2-methyltetrahydrofuran 1.6
    n-hexyl acetate 0.9
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 7.37
    sec-butyl acetate 0.43
    tert-butyl acetate 1.07
    decalin 0.13
    glycerin 192.31
    diglyme 9.89
    acrylic acid 72.21
    isopropyl myristate 0.39
    n-butyric acid 15.81
    acetyl acetate 1.73
    di(2-ethylhexyl) phthalate 2.93
    ethyl propionate 0.68
    nitromethane 42.31
    1,2-diethoxyethane 0.57
    benzonitrile 1.54
    trioctyl phosphate 1.6
    1-bromopropane 0.14
    gamma-valerolactone 23.88
    n-decanol 0.37
    triethyl phosphate 2.15
    4-methyl-2-pentanol 0.56
    propionitrile 0.71
    vinylene carbonate 15.01
    1,1,2-trichlorotrifluoroethane 48.33
    DMS 2.13
    cumene 0.3
    2-octanol 0.47
    2-hexanone 0.56
    octyl acetate 0.64
    limonene 0.7
    1,2-dimethoxyethane 3.59
    ethyl orthosilicate 1.7
    tributyl phosphate 1.89
    diacetone alcohol 5.17
    N,N-dimethylaniline 1.03
    acrylonitrile 2.43
    aniline 1.91
    1,3-propanediol 28.52
    bromobenzene 0.34
    dibromomethane 0.41
    1,1,2,2-tetrachloroethane 1.49
    2-methyl-cyclohexyl acetate 2.29
    tetrabutyl urea 2.64
    diisobutyl methanol 0.71
    2-phenylethanol 2.85
    styrene 0.21
    dioctyl adipate 1.26
    dimethyl sulfate 15.01
    ethyl butyrate 1.37
    methyl lactate 13.69
    butyl lactate 4.33
    diethyl carbonate 1.34
    propanediol butyl ether 9.7
    triethyl orthoformate 1.69
    p-tert-butyltoluene 0.57
    methyl 4-tert-butylbenzoate 4.68
    morpholine 1.79
    tert-butylamine 0.78
    n-dodecanol 0.28
    dimethoxymethane 2.37
    ethylene carbonate 8.61
    cyrene 19.33
    2-ethoxyethyl acetate 1.44
    2-ethylhexyl acetate 1.34
    1,2,4-trichlorobenzene 1.32
    4-methylpyridine 1.4
    dibutyl ether 0.19
    2,6-dimethyl-4-heptanol 0.71
    DEF 2.77
    dimethyl isosorbide 13.83
    tetrachloroethylene 3.01
    eugenol 6.74
    triacetin 3.23
    span 80 8.31
    1,4-butanediol 13.81
    1,1-dichloroethane 0.21
    2-methyl-1-pentanol 1.21
    methyl formate 26.04
    2-methyl-1-butanol 1.56
    n-decane 0.05
    butyronitrile 0.61
    3,7-dimethyl-1-octanol 0.67
    1-chlorooctane 0.12
    1-chlorotetradecane 0.06
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.12
    cyclooctane 0.08
    cyclopentanol 5.87
    tetrahydropyran 0.43
    tert-amyl methyl ether 0.46
    2,5,8-trioxanonane 9.72
    1-hexene 0.18
    2-isopropoxyethanol 3.37
    2,2,2-trifluoroethanol 83.35
    methyl butyrate 1.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction