N-Acetyl-D-glucosamine-6-phosphate disodium salt

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  • Identifiers

    CAS number
    102029-88-9

    Molecular formula
    C8H16NNaO9P

    SMILES
    CC(=O)NC1C(C(C(OC1O)COP(=O)(O)O)O)O.[Na]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 83.97%
    Savory 25.19%
    Sweet 20.49%
    Cooling 18.59%
    Meaty 17.11%
    Milky 17.0%
    Bitter 15.78%
    Alcoholic 14.85%
    Clean 14.58%
    Cooked 13.97%

     

    Flavor
    Odorless 66.82%
    Bitter 30.23%
    Very mild 29.31%
    Mild 26.96%
    Bland 26.71%
    Sweet-like 26.3%
    Yeast 22.42%
    Very slight 20.73%
    Sour 20.36%
    Formyl 20.25%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.62 (neutral)

    Molecular weight
    324.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2010°C

    Flash point

    • 320.2 ˚C est.

  • Synonyms

    • 102029-88-9
    • N-Acetyl-D-glucosamine 6-phosphate sodium salt
    • N-Acetyl-D-glucosamine-6-phosphate disodium salt
    • D-Glucopyranose, 2-(acetylamino)-2-deoxy-, 6-(dihydrogen phosphate), disodium salt (9CI)
    • MSK168104Na
    • AKOS037647626
    • AS-74299
    • [(5-acetamido-3,4,6-trihydroxyoxan-2-yl)methoxy]phosphonic acid sodium hydride
    • 102029-88-9

  • Applications

    N-Acetyl-D-glucosamine-6-phosphate disodium salt (CAS 102029-88-9) is primarily employed as a biochemical reagent and intermediate in nucleotide-sugar biosynthesis, serving as a precursor toward UDP-N-acetylglucosamine in research and biotechnological applications. It can act as a substrate or reference standard in enzymatic assays of hexosamine-pathway enzymes (for example GlmS and GlmM) and in analytical method development. It is used as a building block for the synthesis of chitin/chitosan derivatives and other glycopolymer materials in polymer, coatings, and materials research. It serves as a reference standard and reagent in analytical chemistry (HPLC/LC-MS) for quantification of GlcNAc-6-P related metabolites. It may be used as a starting point for in vitro pathways to produce UDP-GlcNAc and related glycosyl donors in pharmaceutical and biotechnology contexts.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.24
    methanol 0.98
    isopropanol 0.16
    water 137.66
    ethyl acetate 0.06
    n-propanol 0.15
    acetone 0.28
    n-butanol 0.11
    acetonitrile 0.1
    DMF 9.15
    toluene 0.08
    isobutanol 0.08
    1,4-dioxane 0.56
    methyl acetate 0.07
    THF 0.64
    2-butanone 0.1
    n-pentanol 0.07
    sec-butanol 0.13
    n-hexane 0.05
    ethylene glycol 4.78
    NMP 12.43
    cyclohexane 0.19
    DMSO 24.69
    n-butyl acetate 0.09
    n-octanol 0.13
    chloroform 0.02
    n-propyl acetate 0.05
    acetic acid 1.53
    dichloromethane 0.04
    cyclohexanone 0.41
    propylene glycol 1.67
    isopropyl acetate 0.06
    DMAc 6.64
    2-ethoxyethanol 1.43
    isopentanol 0.09
    n-heptane 0.15
    ethyl formate 0.16
    1,2-dichloroethane 0.05
    n-hexanol 0.16
    2-methoxyethanol 4.41
    isobutyl acetate 0.02
    tetrachloromethane 0.04
    n-pentyl acetate 0.07
    transcutol 1.38
    n-heptanol 0.2
    ethylbenzene 0.05
    MIBK 0.1
    2-propoxyethanol 1.28
    tert-butanol 0.32
    MTBE 0.07
    2-butoxyethanol 0.78
    propionic acid 0.25
    o-xylene 0.16
    formic acid 27.24
    diethyl ether 0.12
    m-xylene 0.09
    p-xylene 0.06
    chlorobenzene 0.01
    dimethyl carbonate 0.47
    n-octane 0.06
    formamide 19.3
    cyclopentanone 0.55
    2-pentanone 0.12
    anisole 0.08
    cyclopentyl methyl ether 0.45
    gamma-butyrolactone 0.68
    1-methoxy-2-propanol 2.18
    pyridine 0.24
    3-pentanone 0.14
    furfural 1.57
    n-dodecane 0.02
    diethylene glycol 5.08
    diisopropyl ether 0.06
    tert-amyl alcohol 0.24
    acetylacetone 0.37
    n-hexadecane 0.03
    acetophenone 0.16
    methyl propionate 0.16
    isopentyl acetate 0.07
    trichloroethylene 0.05
    n-nonanol 0.14
    cyclohexanol 0.35
    benzyl alcohol 0.15
    2-ethylhexanol 0.12
    isooctanol 0.12
    dipropyl ether 0.25
    1,2-dichlorobenzene 0.02
    ethyl lactate 0.32
    propylene carbonate 0.29
    n-methylformamide 2.52
    2-pentanol 0.1
    n-pentane 0.05
    1-propoxy-2-propanol 0.79
    1-methoxy-2-propyl acetate 0.29
    2-(2-methoxypropoxy) propanol 0.84
    mesitylene 0.09
    ε-caprolactone 0.33
    p-cymene 0.09
    epichlorohydrin 0.2
    1,1,1-trichloroethane 0.02
    2-aminoethanol 2.23
    morpholine-4-carbaldehyde 5.97
    sulfolane 5.43
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.24
    n-hexyl acetate 0.08
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 1.09
    sec-butyl acetate 0.03
    tert-butyl acetate 0.12
    decalin 0.04
    glycerin 14.56
    diglyme 2.29
    acrylic acid 0.58
    isopropyl myristate 0.05
    n-butyric acid 0.19
    acetyl acetate 0.09
    di(2-ethylhexyl) phthalate 0.1
    ethyl propionate 0.07
    nitromethane 1.77
    1,2-diethoxyethane 0.16
    benzonitrile 0.06
    trioctyl phosphate 0.1
    1-bromopropane 0.03
    gamma-valerolactone 1.58
    n-decanol 0.11
    triethyl phosphate 0.17
    4-methyl-2-pentanol 0.07
    propionitrile 0.05
    vinylene carbonate 0.25
    1,1,2-trichlorotrifluoroethane 1.9
    DMS 0.11
    cumene 0.04
    2-octanol 0.11
    2-hexanone 0.06
    octyl acetate 0.07
    limonene 0.12
    1,2-dimethoxyethane 1.43
    ethyl orthosilicate 0.16
    tributyl phosphate 0.08
    diacetone alcohol 0.74
    N,N-dimethylaniline 0.22
    acrylonitrile 0.11
    aniline 0.18
    1,3-propanediol 1.41
    bromobenzene 0.01
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.08
    2-methyl-cyclohexyl acetate 0.12
    tetrabutyl urea 0.27
    diisobutyl methanol 0.12
    2-phenylethanol 0.18
    styrene 0.03
    dioctyl adipate 0.07
    dimethyl sulfate 1.85
    ethyl butyrate 0.11
    methyl lactate 1.15
    butyl lactate 0.23
    diethyl carbonate 0.08
    propanediol butyl ether 0.8
    triethyl orthoformate 0.19
    p-tert-butyltoluene 0.09
    methyl 4-tert-butylbenzoate 0.42
    morpholine 0.76
    tert-butylamine 0.15
    n-dodecanol 0.09
    dimethoxymethane 2.13
    ethylene carbonate 0.19
    cyrene 1.8
    2-ethoxyethyl acetate 0.12
    2-ethylhexyl acetate 0.06
    1,2,4-trichlorobenzene 0.04
    4-methylpyridine 0.16
    dibutyl ether 0.08
    2,6-dimethyl-4-heptanol 0.12
    DEF 0.75
    dimethyl isosorbide 1.57
    tetrachloroethylene 0.11
    eugenol 0.57
    triacetin 0.17
    span 80 0.52
    1,4-butanediol 0.6
    1,1-dichloroethane 0.01
    2-methyl-1-pentanol 0.06
    methyl formate 1.68
    2-methyl-1-butanol 0.09
    n-decane 0.05
    butyronitrile 0.05
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.05
    1-chlorotetradecane 0.02
    n-nonane 0.05
    undecane 0.03
    tert-butylcyclohexane 0.02
    cyclooctane 0.12
    cyclopentanol 0.42
    tetrahydropyran 0.22
    tert-amyl methyl ether 0.13
    2,5,8-trioxanonane 2.13
    1-hexene 0.04
    2-isopropoxyethanol 0.48
    2,2,2-trifluoroethanol 2.44
    methyl butyrate 0.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
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Rinse-off products applied to the hair with some hand contact
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Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
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Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction