N-(2-((2-hydroxyethyl)amino)ethyl)stearamide

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  • Identifiers

    CAS number
    141-21-9

    Molecular formula
    C22H46N2O2

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)NCCNCCO

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fishy 40.43%
    Waxy 37.17%
    Odorless 34.27%
    Savory 32.76%
    Meaty 31.63%
    Fatty 28.23%
    Oily 27.49%
    Animal 27.03%
    Cooling 23.52%
    Fresh 21.03%

     

    Flavor
    Bland 36.86%
    Odorless 36.71%
    Mild 33.46%
    Fatty 29.23%
    Faint 27.48%
    Waxy 23.84%
    Slightly waxy 22.52%
    Bay oil 21.32%
    Delicate 21.14%
    Beer 20.09%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.8

    pKa est.
    7.91 (neutral)

    Molecular weight
    370.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    373°C

    Flash point

    • 225.75 ˚C est.

  • Synonyms

    • 141-21-9
    • Stearamidoethyl ethanolamine
    • Octadecanamide, N-[2-[(2-hydroxyethyl)amino]ethyl]-
    • N-[2-[(2-Hydroxyethyl)amino]ethyl]stearamide
    • N-(Ethoxyaminoethyl)stearamide
    • HSDB 6125
    • 8XMG7HCY8D
    • Stearic N-(aminoethyl)ethanolamide
    • N-(2-((2-Hydroxyethyl)amino)ethyl)stearamide
    • N-Stearoyl-N'-(2-hydroxyethyl)ethylenediamine
    • EINECS 205-469-7
    • Ethanolaminoethyl stearamide
    • N-(2-Hydroxyethyl)-N'-octadecanoylethylenediamine
    • n-{2-[(2-hydroxyethyl)amino]ethyl}octadecanamide
    • Ethanol, 2-(2-stearamidoethylamino)-
    • Octadecanamide, N-(2-((2-hydroxyethyl)amino)ethyl)-
    • DTXSID9059703
    • N-Stearoyl-N'-(beta-hydroxyethyl)ethylenediamine
    • N-[2-[(2-Hydroxyethyl)amino]ethyl]octadecanamide
    • N-(2-HYDROXYETHYL)-N'-STEAROYLETHYLENEDIAMINE
    • N-(2-((2-Hydroxyethyl)amino)ethyl)octadecanamide
    • N-STEAROYL-N'-(.BETA.-HYDROXYETHYL)ETHYLENEDIAMINE
    • N-(2-HYDROXYETHYL)-N'-STEAROYLETHYLENEDIAMINE [HSDB]
    • RefChem:824247
    • octadecanamide, n-2-(2-hydroxyethyl)aminoethyl-
    • DTXCID5034567
    • Ethanol, 2(2stearamidoethylamino)
    • NStearoylN'(2hydroxyethyl)ethylenediamine
    • N(2((2Hydroxyethyl)amino)ethyl)stearamide
    • STEARAMIDOETHYL ETHANOLAMINE [INCI]
    • NStearoylN'(betahydroxyethyl)ethylenediamine
    • N(2Hydroxyethyl)N'octadecanoylethylenediamine
    • N(2((2Hydroxyethyl)amino)ethyl)octadecanamide
    • Octadecanamide, N(2((2hydroxyethyl)amino)ethyl)
    • N-[2-(2-hydroxyethylamino)ethyl]octadecanamide
    • UNII-8XMG7HCY8D
    • Octadecanamide,N-[2-[(2-hydroxyethyl)amino]ethyl]-
    • SCHEMBL5418052
    • N-stearoyl-N'-hydroxyethyl ethylene diamine
    • NS00014109
    • N-[2-(2-hydroxyethyl)aminoethyl]octadecanamide
    • Q27271163
    • 141-21-9

  • Applications

    N-(2-((2-hydroxyethyl)amino)ethyl)stearamide (CAS 141-21-9) is a fatty‑amide derivative with amphiphilic character that is commonly used as a surfactant and conditioning aid in cosmetics and personal care, helping to stabilize emulsions, improve texture, and provide slip in creams, lotions, shampoos, and cleaners. It may also serve as a processing aid or lubricity additive in polymer and plastics formulation, reducing friction during extrusion or molding. In coatings and inks, it can function as a surfactant or dispersant to improve pigment dispersion and film formation. It may be employed in cleaning formulations as a surfactant. Additionally, it can act as an intermediate or precursor in chemical synthesis or formulation development, enabling further functionalization. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.94
    methanol 11.44
    isopropanol 2.47
    water 0.55
    ethyl acetate 8.17
    n-propanol 4.38
    acetone 7.75
    n-butanol 4.64
    acetonitrile 2.78
    DMF 30.85
    toluene 4.11
    isobutanol 4.25
    1,4-dioxane 14.73
    methyl acetate 6.85
    THF 48.68
    2-butanone 9.99
    n-pentanol 5.42
    sec-butanol 4.28
    n-hexane 1.03
    ethylene glycol 1.73
    NMP 117.21
    cyclohexane 3.75
    DMSO 67.73
    n-butyl acetate 15.48
    n-octanol 9.45
    chloroform 44.32
    n-propyl acetate 17.61
    acetic acid 21.13
    dichloromethane 38.32
    cyclohexanone 55.52
    propylene glycol 3.27
    isopropyl acetate 10.43
    DMAc 83.46
    2-ethoxyethanol 18.06
    isopentanol 6.24
    n-heptane 1.58
    ethyl formate 9.6
    1,2-dichloroethane 22.47
    n-hexanol 5.08
    2-methoxyethanol 18.14
    isobutyl acetate 13.28
    tetrachloromethane 12.76
    n-pentyl acetate 30.98
    transcutol 110.74
    n-heptanol 9.42
    ethylbenzene 4.3
    MIBK 12.19
    2-propoxyethanol 17.93
    tert-butanol 6.13
    MTBE 6.57
    2-butoxyethanol 31.14
    propionic acid 12.3
    o-xylene 6.44
    formic acid 13.34
    diethyl ether 3.43
    m-xylene 4.65
    p-xylene 6.55
    chlorobenzene 9.5
    dimethyl carbonate 6.05
    n-octane 1.1
    formamide 17.13
    cyclopentanone 55.8
    2-pentanone 10.14
    anisole 8.82
    cyclopentyl methyl ether 23.92
    gamma-butyrolactone 64.8
    1-methoxy-2-propanol 16.22
    pyridine 17.82
    3-pentanone 10.63
    furfural 61.07
    n-dodecane 0.7
    diethylene glycol 12.28
    diisopropyl ether 2.87
    tert-amyl alcohol 9.17
    acetylacetone 19.84
    n-hexadecane 0.8
    acetophenone 20.55
    methyl propionate 9.71
    isopentyl acetate 18.61
    trichloroethylene 48.83
    n-nonanol 10.11
    cyclohexanol 14.08
    benzyl alcohol 9.75
    2-ethylhexanol 7.06
    isooctanol 9.95
    dipropyl ether 9.2
    1,2-dichlorobenzene 15.31
    ethyl lactate 15.29
    propylene carbonate 41.86
    n-methylformamide 13.28
    2-pentanol 3.68
    n-pentane 0.63
    1-propoxy-2-propanol 19.61
    1-methoxy-2-propyl acetate 22.85
    2-(2-methoxypropoxy) propanol 30.65
    mesitylene 4.55
    ε-caprolactone 55.72
    p-cymene 5.68
    epichlorohydrin 40.35
    1,1,1-trichloroethane 24.08
    2-aminoethanol 4.94
    morpholine-4-carbaldehyde 61.06
    sulfolane 161.58
    2,2,4-trimethylpentane 1.42
    2-methyltetrahydrofuran 26.41
    n-hexyl acetate 27.58
    isooctane 0.65
    2-(2-butoxyethoxy)ethanol 40.04
    sec-butyl acetate 14.25
    tert-butyl acetate 19.84
    decalin 2.33
    glycerin 10.44
    diglyme 88.44
    acrylic acid 12.35
    isopropyl myristate 8.69
    n-butyric acid 20.72
    acetyl acetate 10.44
    di(2-ethylhexyl) phthalate 13.78
    ethyl propionate 13.64
    nitromethane 27.85
    1,2-diethoxyethane 22.41
    benzonitrile 10.49
    trioctyl phosphate 9.44
    1-bromopropane 8.39
    gamma-valerolactone 86.4
    n-decanol 6.23
    triethyl phosphate 19.81
    4-methyl-2-pentanol 4.23
    propionitrile 4.03
    vinylene carbonate 32.41
    1,1,2-trichlorotrifluoroethane 69.94
    DMS 16.91
    cumene 4.7
    2-octanol 7.56
    2-hexanone 14.31
    octyl acetate 11.65
    limonene 8.74
    1,2-dimethoxyethane 35.16
    ethyl orthosilicate 20.03
    tributyl phosphate 13.0
    diacetone alcohol 27.53
    N,N-dimethylaniline 10.76
    acrylonitrile 5.47
    aniline 7.16
    1,3-propanediol 7.35
    bromobenzene 9.62
    dibromomethane 21.45
    1,1,2,2-tetrachloroethane 55.45
    2-methyl-cyclohexyl acetate 23.99
    tetrabutyl urea 19.98
    diisobutyl methanol 5.71
    2-phenylethanol 9.78
    styrene 4.34
    dioctyl adipate 20.8
    dimethyl sulfate 24.02
    ethyl butyrate 19.83
    methyl lactate 12.64
    butyl lactate 32.17
    diethyl carbonate 12.89
    propanediol butyl ether 29.35
    triethyl orthoformate 24.2
    p-tert-butyltoluene 5.54
    methyl 4-tert-butylbenzoate 35.6
    morpholine 24.47
    tert-butylamine 4.12
    n-dodecanol 4.28
    dimethoxymethane 12.42
    ethylene carbonate 26.52
    cyrene 42.31
    2-ethoxyethyl acetate 36.61
    2-ethylhexyl acetate 16.76
    1,2,4-trichlorobenzene 20.33
    4-methylpyridine 14.5
    dibutyl ether 12.73
    2,6-dimethyl-4-heptanol 5.71
    DEF 25.25
    dimethyl isosorbide 63.54
    tetrachloroethylene 45.1
    eugenol 32.93
    triacetin 48.06
    span 80 27.83
    1,4-butanediol 4.33
    1,1-dichloroethane 13.51
    2-methyl-1-pentanol 7.53
    methyl formate 9.31
    2-methyl-1-butanol 6.6
    n-decane 1.55
    butyronitrile 4.9
    3,7-dimethyl-1-octanol 9.04
    1-chlorooctane 7.32
    1-chlorotetradecane 2.21
    n-nonane 1.4
    undecane 0.97
    tert-butylcyclohexane 1.82
    cyclooctane 1.35
    cyclopentanol 15.4
    tetrahydropyran 18.85
    tert-amyl methyl ether 9.73
    2,5,8-trioxanonane 54.02
    1-hexene 2.67
    2-isopropoxyethanol 14.21
    2,2,2-trifluoroethanol 17.51
    methyl butyrate 21.72

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction