Myristoyl Hexapeptide-16

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  • Identifiers

    CAS number
    959610-54-9

    Molecular formula
    C47H91N9O8

    SMILES
    CCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 52.89%
    Savory 40.72%
    Cooling 39.96%
    Fishy 34.13%
    Meaty 28.13%
    Mint 22.29%
    Animal 21.02%
    Oily 18.32%
    Cheesy 17.26%
    Milky 16.79%

     

    Flavor
    Bitter 44.92%
    Odorless 43.73%
    Bland 37.45%
    Mild 23.95%
    Sweet-like 19.92%
    Cedarleaf 19.07%
    Nitrile 18.86%
    Oriental 18.54%
    Slightly waxy 17.98%
    Faint 17.98%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    8.68 (weak base)

    Molecular weight
    910.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2058°C

    Flash point

    • 318.95 ˚C est.

  • Synonyms

    • Myristoyl Hexapeptide-16
    • 959610-54-9
    • Myristoyl Hexapeptide-16 (acetate)
    • orb1943035
    • HY-P5235
    • DA-55800
    • CS-0863809
    • (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-4-methyl-2-(tetradecanoylamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]hexanoic acid
    • 959610-54-9

  • Applications

    Myristoyl Hexapeptide-16, CAS 959610-54-9, is used primarily in cosmetics and personal care as a peptide active ingredient to support skin conditioning and surface texture in formulations. In practice, it is commonly included in products such as serums, day and night creams, and masks to enhance a smooth feel and uniform surface appearance. It is also considered a component in cosmetic formulation development, helping optimize peptide delivery properties and the performance of the delivery system within formulas. Additionally, with its peptide nature, it may function as a signaling element in skin-care systems to interact with epidermal cells at the surface, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.47
    methanol 27.52
    isopropanol 7.58
    water 4.49
    ethyl acetate 8.37
    n-propanol 9.83
    acetone 16.9
    n-butanol 6.33
    acetonitrile 4.82
    DMF 38.73
    toluene 2.83
    isobutanol 5.91
    1,4-dioxane 15.5
    methyl acetate 10.65
    THF 29.18
    2-butanone 13.15
    n-pentanol 6.56
    sec-butanol 6.75
    n-hexane 0.67
    ethylene glycol 16.23
    NMP 122.87
    cyclohexane 0.78
    DMSO 69.75
    n-butyl acetate 5.8
    n-octanol 2.43
    chloroform 7.26
    n-propyl acetate 6.98
    acetic acid 86.69
    dichloromethane 7.38
    cyclohexanone 24.97
    propylene glycol 19.44
    isopropyl acetate 6.22
    DMAc 79.83
    2-ethoxyethanol 28.82
    isopentanol 4.5
    n-heptane 0.43
    ethyl formate 10.12
    1,2-dichloroethane 6.83
    n-hexanol 3.59
    2-methoxyethanol 40.67
    isobutyl acetate 3.82
    tetrachloromethane 3.37
    n-pentyl acetate 5.82
    transcutol 63.94
    n-heptanol 3.36
    ethylbenzene 1.97
    MIBK 4.75
    2-propoxyethanol 19.97
    tert-butanol 6.4
    MTBE 3.65
    2-butoxyethanol 18.35
    propionic acid 22.06
    o-xylene 2.9
    formic acid 74.53
    diethyl ether 3.71
    m-xylene 2.05
    p-xylene 2.86
    chlorobenzene 3.06
    dimethyl carbonate 11.77
    n-octane 0.3
    formamide 55.87
    cyclopentanone 36.14
    2-pentanone 9.28
    anisole 3.96
    cyclopentyl methyl ether 10.2
    gamma-butyrolactone 48.36
    1-methoxy-2-propanol 26.19
    pyridine 13.24
    3-pentanone 9.05
    furfural 43.06
    n-dodecane 0.16
    diethylene glycol 26.84
    diisopropyl ether 1.24
    tert-amyl alcohol 6.92
    acetylacetone 18.41
    n-hexadecane 0.17
    acetophenone 8.88
    methyl propionate 11.24
    isopentyl acetate 5.15
    trichloroethylene 13.06
    n-nonanol 2.62
    cyclohexanol 7.36
    benzyl alcohol 7.6
    2-ethylhexanol 2.23
    isooctanol 2.45
    dipropyl ether 3.0
    1,2-dichlorobenzene 3.21
    ethyl lactate 9.64
    propylene carbonate 24.21
    n-methylformamide 25.49
    2-pentanol 3.81
    n-pentane 0.51
    1-propoxy-2-propanol 13.68
    1-methoxy-2-propyl acetate 12.4
    2-(2-methoxypropoxy) propanol 15.92
    mesitylene 1.22
    ε-caprolactone 30.05
    p-cymene 1.09
    epichlorohydrin 27.25
    1,1,1-trichloroethane 5.7
    2-aminoethanol 20.4
    morpholine-4-carbaldehyde 68.14
    sulfolane 108.39
    2,2,4-trimethylpentane 0.31
    2-methyltetrahydrofuran 15.44
    n-hexyl acetate 5.43
    isooctane 0.13
    2-(2-butoxyethoxy)ethanol 24.25
    sec-butyl acetate 5.03
    tert-butyl acetate 6.16
    decalin 0.48
    glycerin 47.27
    diglyme 36.7
    acrylic acid 29.99
    isopropyl myristate 1.75
    n-butyric acid 19.57
    acetyl acetate 10.27
    di(2-ethylhexyl) phthalate 3.37
    ethyl propionate 6.61
    nitromethane 54.78
    1,2-diethoxyethane 8.86
    benzonitrile 4.21
    trioctyl phosphate 2.68
    1-bromopropane 2.62
    gamma-valerolactone 74.05
    n-decanol 1.86
    triethyl phosphate 4.82
    4-methyl-2-pentanol 1.99
    propionitrile 3.48
    vinylene carbonate 18.56
    1,1,2-trichlorotrifluoroethane 54.0
    DMS 9.66
    cumene 1.42
    2-octanol 1.99
    2-hexanone 8.28
    octyl acetate 3.16
    limonene 1.62
    1,2-dimethoxyethane 22.16
    ethyl orthosilicate 4.15
    tributyl phosphate 3.33
    diacetone alcohol 15.73
    N,N-dimethylaniline 4.27
    acrylonitrile 5.46
    aniline 6.58
    1,3-propanediol 22.1
    bromobenzene 2.25
    dibromomethane 4.35
    1,1,2,2-tetrachloroethane 13.6
    2-methyl-cyclohexyl acetate 5.37
    tetrabutyl urea 5.7
    diisobutyl methanol 1.06
    2-phenylethanol 5.12
    styrene 1.91
    dioctyl adipate 3.97
    dimethyl sulfate 33.6
    ethyl butyrate 5.46
    methyl lactate 21.43
    butyl lactate 11.67
    diethyl carbonate 3.72
    propanediol butyl ether 22.43
    triethyl orthoformate 5.68
    p-tert-butyltoluene 1.07
    methyl 4-tert-butylbenzoate 9.99
    morpholine 23.52
    tert-butylamine 2.42
    n-dodecanol 1.3
    dimethoxymethane 18.46
    ethylene carbonate 15.39
    cyrene 28.63
    2-ethoxyethyl acetate 12.38
    2-ethylhexyl acetate 3.95
    1,2,4-trichlorobenzene 5.86
    4-methylpyridine 10.01
    dibutyl ether 2.25
    2,6-dimethyl-4-heptanol 1.06
    DEF 17.39
    dimethyl isosorbide 21.19
    tetrachloroethylene 11.49
    eugenol 9.37
    triacetin 13.77
    span 80 12.87
    1,4-butanediol 12.98
    1,1-dichloroethane 4.68
    2-methyl-1-pentanol 5.31
    methyl formate 23.38
    2-methyl-1-butanol 5.25
    n-decane 0.29
    butyronitrile 2.98
    3,7-dimethyl-1-octanol 1.73
    1-chlorooctane 1.0
    1-chlorotetradecane 0.43
    n-nonane 0.28
    undecane 0.21
    tert-butylcyclohexane 0.35
    cyclooctane 0.33
    cyclopentanol 13.71
    tetrahydropyran 9.32
    tert-amyl methyl ether 4.03
    2,5,8-trioxanonane 24.81
    1-hexene 1.6
    2-isopropoxyethanol 17.08
    2,2,2-trifluoroethanol 46.13
    methyl butyrate 9.21

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction