Myricetin

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  • Identifiers

    CAS number
    529-44-2

    Molecular formula
    C15H10O8

    SMILES
    C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 70.3%
    Phenolic 49.83%
    Burnt 34.76%
    Smoky 21.9%
    Medicinal 19.79%
    Savory 17.16%
    Spicy 16.48%
    Balsamic 14.42%
    Dry 14.36%
    Bitter 14.1%

     

    Flavor
    Bitter 91.98%
    Odorless 29.11%
    Bland 22.96%
    Sweet-like 22.53%
    Mild 21.66%
    Cedarleaf 20.52%
    Eugenol 20.46%
    Rotten 20.27%
    Very strong 20.03%
    Nitrile 19.99%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.2

    pKa est.
    10.58 (weak base)

    Molecular weight
    318.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1173°C

    Melting point expt.

    • 357 °C

    Flash point

    • 271.99 ˚C est.

    Solubility expt.

    • Sparingly soluble in boiling water; soluble in alcohol. Practically insoluble in chloroform, acetic acid

  • Synonyms

    • myricetin
    • 529-44-2
    • Cannabiscetin
    • Myricetol
    • 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
    • Myricitin
    • 3,3',4',5,5',7-Hexahydroxyflavone
    • 3,5,7,3',4',5'-Hexahydroxyflavone
    • 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
    • 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
    • delphidenolon 1575
    • 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one
    • 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-
    • 76XC01FTOJ
    • NSC-407290
    • DTXSID8022400
    • FLAVONE, 3,3',4',5,5',7-HEXAHYDROXY-
    • CHEBI:18152
    • RefChem:6547
    • DTXCID002400
    • 3,4,5-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-7-one
    • 208-463-2
    • MFCD00006827
    • NSC 407290
    • NSC407290
    • CHEMBL164
    • SMR001233193
    • CCRIS 5838
    • SR-01000076005
    • EINECS 208-463-2
    • UNII-76XC01FTOJ
    • BRN 0332331
    • myricetone
    • Cannabiscetin;
    • Myrc
    • Myricetol;
    • HSDB 7682
    • 4gqr
    • Prestwick_342
    • Myricetin (Standard)
    • Spectrum_001501
    • SpecPlus_000531
    • MYRICETIN [MI]
    • MYRICETIN [HSDB]
    • Prestwick0_000465
    • Prestwick1_000465
    • Prestwick2_000465
    • Prestwick3_000465
    • Spectrum4_001272
    • Spectrum5_000692
    • Lopac-M-6760
    • Myricetin (Cannabiscetin)
    • Myricetin from Myrica cerifera leaf and bark
    • BIDD:PXR0079
    • Lopac0_000740
    • SCHEMBL19302
    • BSPBio_000570
    • KBioGR_001884
    • KBioSS_001981
    • MLS002153825
    • MLS006010718
    • BIDD:ER0142
    • DivK1c_006627
    • Myricetin, analytical standard
    • SPBio_002509
    • BPBio1_000628
    • MEGxp0_000357
    • orb1310476
    • SCHEMBL29357150
    • ACon1_000267
    • BDBM15236
    • cid_5281672
    • GTPL13074
    • KBio1_001571
    • KBio2_001981
    • KBio2_004549
    • KBio2_007117
    • MSK7402
    • 2o63
    • CHEBI: 18152
    • REGID_for_CID_5281672
    • HMS1569M12
    • HMS2096M12
    • HMS2231L04
    • HMS3262C22
    • HMS3656I05
    • Myricetin - CAS 529-44-2
    • Myricetin, >=96.0% (HPLC)
    • Myricetin, >=96.0%, crystalline
    • SAI_0014
    • TNP00286
    • Tox21_500740
    • HB0434
    • HY-15097R
    • LMPK12110001
    • STL284709
    • 3,7,3',4',5'-Hexahydroxyflavone
    • AKOS015903103
    • AC-4533
    • CCG-204825
    • CS-6221
    • DB02375
    • EBC-221043
    • FM26112
    • KS-5268
    • LP00740
    • SDCCGSBI-0050718.P003
    • SDCCGSBI-0050718.P008
    • 3,3',4',5,5',7-hexOH-Flavone
    • Flavone,3',4',5,5',7-hexahydroxy-
    • NCGC00015697-01
    • NCGC00015697-02
    • NCGC00015697-03
    • NCGC00015697-04
    • NCGC00015697-05
    • NCGC00015697-06
    • NCGC00015697-07
    • NCGC00015697-08
    • NCGC00015697-09
    • NCGC00015697-10
    • NCGC00015697-11
    • NCGC00015697-12
    • NCGC00015697-13
    • NCGC00015697-14
    • NCGC00015697-25
    • NCGC00094083-01
    • NCGC00094083-02
    • 529-44-2

  • Applications

    Myricetin (CAS 529-44-2) is used as a natural antioxidant in cosmetics and personal care formulations, helping to stabilize products and protect formulations from oxidative degradation. In food processing and beverages, it is evaluated as a natural antioxidant additive to extend shelf life and preserve color, flavor, and quality. In nutraceuticals and dietary supplements, it is studied as a polyphenol ingredient with potential nutritional support. In pharmaceutical research, it serves as a scaffold for medicinal chemistry investigations and an intermediate for flavonoid derivatives. In polymers, coatings, and inks, it can act as a natural antioxidant stabilizer for polymer systems and coatings formulations. In agriculture and plant science, it is explored in studies of plant bioactivity and defense mechanisms.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.71
    methanol 4.94
    isopropanol 1.65
    water 0.0
    ethyl acetate 1.02
    n-propanol 3.95
    acetone 0.0
    n-butanol 3.37
    acetonitrile 0.02
    DMF 11.06
    toluene 0.01
    isobutanol 1.17
    1,4-dioxane 0.5
    methyl acetate 0.39
    THF 4.3
    2-butanone 0.51
    n-pentanol 0.79
    sec-butanol 5.16
    n-hexane 0.0
    ethylene glycol 4.97
    NMP 21.04
    cyclohexane 0.0
    DMSO 30.5
    n-butyl acetate 0.77
    n-octanol 1.66
    chloroform 0.0
    n-propyl acetate 0.37
    acetic acid 0.48
    dichloromethane 0.0
    cyclohexanone 0.54
    propylene glycol 8.71
    isopropyl acetate 0.63
    DMAc 25.6
    2-ethoxyethanol 19.22
    isopentanol 2.04
    n-heptane 0.01
    ethyl formate 0.31
    1,2-dichloroethane 0.0
    n-hexanol 1.1
    2-methoxyethanol 74.24
    isobutyl acetate 0.06
    tetrachloromethane 0.0
    n-pentyl acetate 0.75
    transcutol 16.98
    n-heptanol 1.7
    ethylbenzene 0.01
    MIBK 0.35
    2-propoxyethanol 23.19
    tert-butanol 1.93
    MTBE 0.49
    2-butoxyethanol 9.54
    propionic acid 1.84
    o-xylene 0.03
    formic acid 2.58
    diethyl ether 0.26
    m-xylene 0.02
    p-xylene 0.01
    chlorobenzene 0.0
    dimethyl carbonate 0.79
    n-octane 0.01
    formamide 5.18
    cyclopentanone 1.26
    2-pentanone 0.44
    anisole 0.13
    cyclopentyl methyl ether 1.21
    gamma-butyrolactone 3.37
    1-methoxy-2-propanol 71.68
    pyridine 0.18
    3-pentanone 0.32
    furfural 1.77
    n-dodecane 0.01
    diethylene glycol 23.07
    diisopropyl ether 0.06
    tert-amyl alcohol 5.3
    acetylacetone 0.41
    n-hexadecane 0.01
    acetophenone 0.22
    methyl propionate 2.59
    isopentyl acetate 0.59
    trichloroethylene 0.0
    n-nonanol 1.72
    cyclohexanol 1.08
    benzyl alcohol 0.29
    2-ethylhexanol 0.6
    isooctanol 0.99
    dipropyl ether 0.82
    1,2-dichlorobenzene 0.0
    ethyl lactate 2.56
    propylene carbonate 0.66
    n-methylformamide 6.17
    2-pentanol 2.33
    n-pentane 0.0
    1-propoxy-2-propanol 16.05
    1-methoxy-2-propyl acetate 4.74
    2-(2-methoxypropoxy) propanol 7.7
    mesitylene 0.01
    ε-caprolactone 2.42
    p-cymene 0.05
    epichlorohydrin 0.89
    1,1,1-trichloroethane 0.0
    2-aminoethanol 13.19
    morpholine-4-carbaldehyde 14.88
    sulfolane 15.13
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 1.91
    n-hexyl acetate 1.22
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 11.81
    sec-butyl acetate 0.32
    tert-butyl acetate 0.99
    decalin 0.0
    glycerin 32.51
    diglyme 14.34
    acrylic acid 1.35
    isopropyl myristate 0.43
    n-butyric acid 2.79
    acetyl acetate 0.09
    di(2-ethylhexyl) phthalate 0.39
    ethyl propionate 0.86
    nitromethane 0.74
    1,2-diethoxyethane 1.34
    benzonitrile 0.04
    trioctyl phosphate 0.56
    1-bromopropane 0.0
    gamma-valerolactone 9.08
    n-decanol 1.05
    triethyl phosphate 0.56
    4-methyl-2-pentanol 0.7
    propionitrile 0.17
    vinylene carbonate 0.25
    1,1,2-trichlorotrifluoroethane 3.53
    DMS 0.61
    cumene 0.01
    2-octanol 1.1
    2-hexanone 0.26
    octyl acetate 0.77
    limonene 0.09
    1,2-dimethoxyethane 8.31
    ethyl orthosilicate 0.53
    tributyl phosphate 0.43
    diacetone alcohol 9.8
    N,N-dimethylaniline 0.18
    acrylonitrile 0.26
    aniline 0.15
    1,3-propanediol 22.14
    bromobenzene 0.0
    dibromomethane 0.0
    1,1,2,2-tetrachloroethane 0.0
    2-methyl-cyclohexyl acetate 0.4
    tetrabutyl urea 1.05
    diisobutyl methanol 0.4
    2-phenylethanol 0.48
    styrene 0.01
    dioctyl adipate 0.69
    dimethyl sulfate 2.46
    ethyl butyrate 0.99
    methyl lactate 11.4
    butyl lactate 2.63
    diethyl carbonate 0.36
    propanediol butyl ether 8.64
    triethyl orthoformate 1.1
    p-tert-butyltoluene 0.06
    methyl 4-tert-butylbenzoate 1.54
    morpholine 5.38
    tert-butylamine 0.32
    n-dodecanol 0.55
    dimethoxymethane 7.79
    ethylene carbonate 0.23
    cyrene 5.31
    2-ethoxyethyl acetate 1.4
    2-ethylhexyl acetate 0.36
    1,2,4-trichlorobenzene 0.01
    4-methylpyridine 0.13
    dibutyl ether 0.51
    2,6-dimethyl-4-heptanol 0.4
    DEF 5.25
    dimethyl isosorbide 7.26
    tetrachloroethylene 0.0
    eugenol 2.12
    triacetin 1.2
    span 80 4.9
    1,4-butanediol 2.54
    1,1-dichloroethane 0.0
    2-methyl-1-pentanol 0.75
    methyl formate 0.88
    2-methyl-1-butanol 3.08
    n-decane 0.02
    butyronitrile 0.14
    3,7-dimethyl-1-octanol 0.81
    1-chlorooctane 0.07
    1-chlorotetradecane 0.02
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.0
    cyclooctane 0.0
    cyclopentanol 1.71
    tetrahydropyran 0.32
    tert-amyl methyl ether 1.52
    2,5,8-trioxanonane 10.08
    1-hexene 0.01
    2-isopropoxyethanol 5.46
    2,2,2-trifluoroethanol 0.28
    methyl butyrate 0.97

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction