Monosodium malate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    58214-38-3

    Molecular formula
    C4H5NaO5

    SMILES
    C(C(C(=O)O)O)C(=O)[O-].[Na+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 67.38%
    Sour 36.06%
    Caramellic 34.6%
    Buttery 29.06%
    Sweet 26.73%
    Sharp 23.16%
    Burnt 21.69%
    Winey 21.14%
    Milky 20.71%
    Clean 20.22%

     

    Flavor
    Odorless 73.23%
    Very mild 37.96%
    Sour 36.78%
    Mild 27.34%
    Caramellic 25.34%
    Yeast 22.75%
    Bland 22.71%
    Acidic 22.59%
    Sweet-like 21.84%
    Faint 20.58%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.33 (weak acid)

    Molecular weight
    156.07 g/mol

    Flash point

    • 141.79 ˚C est.

  • Synonyms

    • monosodium malate
    • Sodium hydrogen malate
    • 58214-38-3
    • sodium hydrogen dl-malate
    • UNII-VJ2LXD23XD
    • VJ2LXD23XD
    • EINECS 261-169-6
    • Butanedioic acid, hydroxy-, monosodium salt
    • 57467-17-1
    • INS NO.350(I)
    • DTXSID70905053
    • MALIC ACID MONOSODIUM SALT
    • INS-350(I)
    • E-350(I)
    • DL-Malic acid monosodium salt
    • Butanedioic acid, 2-hydroxy-, sodium salt (1:1)
    • DOJOZCIMYABYPO-UHFFFAOYSA-M
    • DTXCID001334159
    • DB-256113
    • F77967
    • Q27291856
    • 261-169-6

  • Applications

    Monosodium malate (CAS 58214-38-3) is commonly used as an acidity regulator and buffering agent in foods and beverages to control pH and stabilize flavors; it also acts as a chelating agent in cleaning products and detergents, improving metal ion sequestration and cleaning performance. In cosmetics and personal care, it functions as a pH adjuster and stabilizer, and its chelating properties help enhance formulation stability. It may be employed in pharmaceutical formulations as a buffering component and excipient. In industrial manufacturing and polymer processing, it can serve as a processing aid and stabilizer, helping manage viscosity and metal-catalyzed degradation. It is also used in coatings and inks to regulate acidity and chelate metal ions, improving compatibility and color stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1165.82
    methanol 2321.83
    isopropanol 705.33
    water 1974.53
    ethyl acetate 56.63
    n-propanol 767.32
    acetone 557.14
    n-butanol 534.8
    acetonitrile 226.29
    DMF 2497.85
    toluene 22.67
    isobutanol 357.61
    1,4-dioxane 489.78
    methyl acetate 164.59
    THF 611.4
    2-butanone 249.07
    n-pentanol 248.5
    sec-butanol 441.75
    n-hexane 14.33
    ethylene glycol 1144.25
    NMP 602.07
    cyclohexane 20.51
    DMSO 2665.51
    n-butyl acetate 19.13
    n-octanol 48.75
    chloroform 22.07
    n-propyl acetate 43.49
    acetic acid 256.09
    dichloromethane 62.78
    cyclohexanone 115.52
    propylene glycol 582.73
    isopropyl acetate 27.89
    DMAc 1209.06
    2-ethoxyethanol 948.29
    isopentanol 291.18
    n-heptane 10.14
    ethyl formate 244.56
    1,2-dichloroethane 108.92
    n-hexanol 81.74
    2-methoxyethanol 2073.34
    isobutyl acetate 10.74
    tetrachloromethane 11.3
    n-pentyl acetate 16.64
    transcutol 318.12
    n-heptanol 49.14
    ethylbenzene 19.37
    MIBK 48.62
    2-propoxyethanol 260.14
    tert-butanol 674.33
    MTBE 174.17
    2-butoxyethanol 154.72
    propionic acid 155.33
    o-xylene 29.23
    formic acid 977.59
    diethyl ether 206.34
    m-xylene 16.24
    p-xylene 17.52
    chlorobenzene 8.22
    dimethyl carbonate 101.34
    n-octane 4.88
    formamide 1590.28
    cyclopentanone 190.45
    2-pentanone 146.14
    anisole 85.24
    cyclopentyl methyl ether 121.1
    gamma-butyrolactone 185.68
    1-methoxy-2-propanol 736.62
    pyridine 115.07
    3-pentanone 87.31
    furfural 194.85
    n-dodecane 3.37
    diethylene glycol 436.52
    diisopropyl ether 24.09
    tert-amyl alcohol 406.3
    acetylacetone 84.56
    n-hexadecane 3.39
    acetophenone 49.44
    methyl propionate 100.9
    isopentyl acetate 13.12
    trichloroethylene 45.9
    n-nonanol 43.04
    cyclohexanol 147.35
    benzyl alcohol 106.12
    2-ethylhexanol 27.82
    isooctanol 29.24
    dipropyl ether 50.28
    1,2-dichlorobenzene 7.82
    ethyl lactate 54.98
    propylene carbonate 45.86
    n-methylformamide 1422.55
    2-pentanol 189.81
    n-pentane 25.5
    1-propoxy-2-propanol 112.4
    1-methoxy-2-propyl acetate 28.69
    2-(2-methoxypropoxy) propanol 106.1
    mesitylene 11.99
    ε-caprolactone 91.23
    p-cymene 8.0
    epichlorohydrin 311.07
    1,1,1-trichloroethane 18.68
    2-aminoethanol 1271.01
    morpholine-4-carbaldehyde 623.6
    sulfolane 260.96
    2,2,4-trimethylpentane 5.62
    2-methyltetrahydrofuran 239.85
    n-hexyl acetate 23.7
    isooctane 3.35
    2-(2-butoxyethoxy)ethanol 164.16
    sec-butyl acetate 18.32
    tert-butyl acetate 34.33
    decalin 5.76
    glycerin 836.06
    diglyme 376.12
    acrylic acid 147.59
    isopropyl myristate 10.64
    n-butyric acid 117.03
    acetyl acetate 18.88
    di(2-ethylhexyl) phthalate 13.89
    ethyl propionate 40.98
    nitromethane 544.39
    1,2-diethoxyethane 70.01
    benzonitrile 29.14
    trioctyl phosphate 13.18
    1-bromopropane 53.31
    gamma-valerolactone 318.64
    n-decanol 32.82
    triethyl phosphate 15.88
    4-methyl-2-pentanol 58.8
    propionitrile 157.45
    vinylene carbonate 52.11
    1,1,2-trichlorotrifluoroethane 163.7
    DMS 18.24
    cumene 13.52
    2-octanol 27.08
    2-hexanone 70.7
    octyl acetate 17.35
    limonene 11.77
    1,2-dimethoxyethane 1090.42
    ethyl orthosilicate 16.06
    tributyl phosphate 12.01
    diacetone alcohol 123.95
    N,N-dimethylaniline 86.92
    acrylonitrile 181.45
    aniline 67.15
    1,3-propanediol 1111.68
    bromobenzene 5.42
    dibromomethane 39.17
    1,1,2,2-tetrachloroethane 50.63
    2-methyl-cyclohexyl acetate 12.84
    tetrabutyl urea 33.12
    diisobutyl methanol 17.27
    2-phenylethanol 42.58
    styrene 19.44
    dioctyl adipate 17.67
    dimethyl sulfate 164.84
    ethyl butyrate 22.16
    methyl lactate 138.93
    butyl lactate 25.33
    diethyl carbonate 15.95
    propanediol butyl ether 121.2
    triethyl orthoformate 21.43
    p-tert-butyltoluene 8.18
    methyl 4-tert-butylbenzoate 43.45
    morpholine 692.98
    tert-butylamine 278.99
    n-dodecanol 24.61
    dimethoxymethane 844.91
    ethylene carbonate 51.53
    cyrene 117.39
    2-ethoxyethyl acetate 26.27
    2-ethylhexyl acetate 8.89
    1,2,4-trichlorobenzene 9.45
    4-methylpyridine 105.3
    dibutyl ether 29.15
    2,6-dimethyl-4-heptanol 17.27
    DEF 317.63
    dimethyl isosorbide 96.11
    tetrachloroethylene 44.58
    eugenol 58.56
    triacetin 20.33
    span 80 52.38
    1,4-butanediol 488.3
    1,1-dichloroethane 39.84
    2-methyl-1-pentanol 140.25
    methyl formate 913.05
    2-methyl-1-butanol 296.74
    n-decane 5.12
    butyronitrile 136.92
    3,7-dimethyl-1-octanol 26.98
    1-chlorooctane 10.72
    1-chlorotetradecane 5.34
    n-nonane 5.46
    undecane 4.04
    tert-butylcyclohexane 4.19
    cyclooctane 8.76
    cyclopentanol 236.65
    tetrahydropyran 237.11
    tert-amyl methyl ether 127.86
    2,5,8-trioxanonane 257.25
    1-hexene 32.91
    2-isopropoxyethanol 317.77
    2,2,2-trifluoroethanol 189.02
    methyl butyrate 77.78

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction