Monolaurin

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  • Identifiers

    CAS number
    27215-38-9

    Molecular formula
    C15H30O4

    SMILES
    CCCCCCCCCCCC(=O)OCC(CO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fatty 61.97%
    Waxy 53.22%
    Oily 50.49%
    Odorless 35.63%
    Buttery 35.08%
    Creamy 32.06%
    Fruity 31.09%
    Peach 31.08%
    Sweet 29.16%
    Lactonic 28.46%

     

    Flavor
    Waxy 58.85%
    Oily 43.83%
    Fatty 43.33%
    Mild 37.82%
    Sweet 34.61%
    Soapy 34.47%
    Fruity 33.23%
    Creamy 32.19%
    Odorless 29.45%
    Bland 28.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    6.73 (neutral)

    Molecular weight
    274.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    372°C

    Flash point

    • 178.08 ˚C est.

  • Synonyms

    • Monolaurin
    • GLYCERYL LAURATE
    • Glycerol monolaurate
    • 27215-38-9
    • Monolauroylglycerin
    • Glycerin monolaurate
    • Cithrol GML
    • Dodecanoic acid, monoester with 1,2,3-propanetriol
    • Laurin, mono-
    • Glycerox L 8
    • Aldo MLD
    • Monoglycerol laurate
    • Grindtek ML 90
    • Monomuls L 90
    • Dimodan ML 90
    • Imwitor 312
    • Sunsoft 750
    • Sunsoft 757
    • Monomuls 90L12
    • Monododecanoyl glycerol
    • Tegin L 90
    • Lauric acid monoglyceride
    • Poem M 300
    • M 300
    • Y98611C087
    • Monolauroyal Glycerol
    • LAURACIDIN
    • RefChem:926088
    • GlyTouCan:G17003ES
    • RIKEMAL M 300
    • RYLO-MG 12
    • MONOMULS 90-45
    • ELECTROSTRIPPER TS 14B
    • DENON 2659
    • DTXSID8051469
    • Mi Deurium Antibacterial Wet Wipes
    • G17003ES
    • 248-337-4
    • Glycerine monolaurate
    • NSC-4837
    • NSC4837
    • 2,3-Dihydroxypropyl dodecanoate
    • 142-18-7
    • 1-Monolaurin
    • Lauricidin
    • Glyceryl monolaurate
    • Glycerol 1-laurate
    • 1-Monolauroyl-rac-glycerol
    • 1-Glyceryl laurate
    • 1-Lauroyl-rac-glycerol
    • 1-Monododecanoylglycerol
    • Laurin, 1-mono-
    • DL-alpha-Laurin
    • Glycerin 1-monolaurate
    • Glycerol 1-monolaurate
    • Lauric acid 1-monoglyceride
    • Dodecanoic acid, 2,3-dihydroxypropyl ester
    • 2,3-Dihydroxypropyl laurate
    • Glyceryl monododecanoate
    • .alpha.-monolaurin
    • 1-monolauroylglycerol
    • MFCD00037815
    • 3-Dodecanoyloxy-1,2-propanediol
    • (+-)-Glyceryl 1-monododecanoate
    • Dodecanoic acid alpha-monoglyceride
    • C15H30O4
    • glyceryl 1-laurate
    • (+-)-2,3-Dihydroxypropyl dodecanoate
    • 40738-26-9
    • Glycerol .alpha.-monolaurate
    • WR963Y5QYW
    • 1-Monododecanoyl-rac-glycerol
    • GLYCEROL MONODODECANOATE
    • DTXSID5041275
    • Lauric acid .alpha.-monoglyceride
    • alpha-Monolaurin
    • 1-Monolaurin;1-Lauroyl-rac-glycerol
    • Dodecanoic acid .alpha.-monoglyceride
    • NSC698570
    • NSC-698570
    • NCGC00164528-01
    • DTXCID3021275
    • Glucerol alpha-monolaurate
    • CAS-142-18-7
    • Lauric acid alpha-monoglyceride
    • Glycerol 1-dodecanoate
    • EINECS 205-526-6
    • Glycerol alpha-monolaurate
    • UNII-WR963Y5QYW
    • Lauricidin R
    • rac-1-monolaurin
    • MG 12:0
    • Hodag GML
    • Lauricidin 802
    • Lauricidin 812
    • 1-dodecanoylglycerol
    • Lauric acid, monoester with glycerol
    • rac-1-lauroylglycerol
    • Aldo MLD-K-FG
    • rac-1-dodecanoylglycerol
    • AI3-03482
    • rac-1-monolauroylglycerol
    • UNII:WR963Y5QYW
    • EC 205-526-6
    • Glycerol monolaurate (VAN)
    • Glycerol .alpha.-dodecanoate
    • SCHEMBL16042
    • MLS004773952
    • 2,3-Dihydroxypropyl laurate #
    • CHEMBL510533
    • orb1299426
    • CHEBI:75539
    • CHEBI:75543
    • GLYCEROL 1-MONODODECANOATE
    • MSK2015
    • 1-Lauroyl-rac-glycerol, >=99%
    • UNII-Y98611C087
    • 1,2,3-Propanetriol 1-dodecanoate
    • MAG 12:0
    • NSC 4837
    • rac-2,3-dihydroxypropyl dodecanoate
    • EINECS 248-337-4
    • Tox21_112159
    • Tox21_300759
    • (.+/-.)-Glyceryl 1-monododecanoate
    • AKOS016005827
    • Dodecanoic acid,3-dihydroxypropyl ester
    • 142-18-7

  • Applications

    Monolaurin (CAS 27215-38-9) is the monoglyceride of lauric acid. It is used as an emulsifier, surfactant, and stabilizer in cosmetics and personal care products, improving texture and dispersion in creams, lotions, and sunscreen formulations. Owing to its antimicrobial properties, it is often evaluated as an antimicrobial additive in cosmetics and household cleaning products. In food processing, it serves as an emulsifier and stabilizer in selected food systems (dairy, bakery, confectionery). In industrial manufacturing, it functions as a surfactant and processing aid in coatings and printing inks, improving dispersion and film formation. In pharmaceuticals, it is explored as an excipient in topical formulations with potential antimicrobial activity. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 391.71
    methanol 800.66
    isopropanol 310.85
    water 0.18
    ethyl acetate 396.32
    n-propanol 276.73
    acetone 531.97
    n-butanol 255.06
    acetonitrile 168.23
    DMF 680.13
    toluene 59.92
    isobutanol 223.92
    1,4-dioxane 382.06
    methyl acetate 254.3
    THF 919.41
    2-butanone 343.47
    n-pentanol 199.92
    sec-butanol 245.17
    n-hexane 10.33
    ethylene glycol 44.93
    NMP 606.19
    cyclohexane 37.92
    DMSO 2052.88
    n-butyl acetate 312.35
    n-octanol 89.98
    chloroform 340.42
    n-propyl acetate 415.75
    acetic acid 395.74
    dichloromethane 417.5
    cyclohexanone 727.96
    propylene glycol 105.67
    isopropyl acetate 335.97
    DMAc 650.73
    2-ethoxyethanol 500.56
    isopentanol 294.6
    n-heptane 9.96
    ethyl formate 219.27
    1,2-dichloroethane 409.54
    n-hexanol 144.9
    2-methoxyethanol 701.45
    isobutyl acetate 241.76
    tetrachloromethane 62.25
    n-pentyl acetate 275.95
    transcutol 1459.68
    n-heptanol 99.03
    ethylbenzene 51.66
    MIBK 316.73
    2-propoxyethanol 352.84
    tert-butanol 509.04
    MTBE 311.45
    2-butoxyethanol 293.94
    propionic acid 254.51
    o-xylene 70.48
    formic acid 138.75
    diethyl ether 209.77
    m-xylene 64.51
    p-xylene 73.93
    chlorobenzene 110.86
    dimethyl carbonate 92.62
    n-octane 6.09
    formamide 275.07
    cyclopentanone 764.09
    2-pentanone 403.87
    anisole 147.06
    cyclopentyl methyl ether 358.28
    gamma-butyrolactone 761.18
    1-methoxy-2-propanol 573.48
    pyridine 260.09
    3-pentanone 227.54
    furfural 554.36
    n-dodecane 4.59
    diethylene glycol 250.9
    diisopropyl ether 77.84
    tert-amyl alcohol 359.86
    acetylacetone 550.48
    n-hexadecane 5.45
    acetophenone 221.81
    methyl propionate 270.27
    isopentyl acetate 300.45
    trichloroethylene 600.34
    n-nonanol 80.82
    cyclohexanol 310.91
    benzyl alcohol 153.6
    2-ethylhexanol 110.84
    isooctanol 97.54
    dipropyl ether 129.63
    1,2-dichlorobenzene 139.55
    ethyl lactate 170.18
    propylene carbonate 394.28
    n-methylformamide 311.52
    2-pentanol 190.37
    n-pentane 7.57
    1-propoxy-2-propanol 293.11
    1-methoxy-2-propyl acetate 307.32
    2-(2-methoxypropoxy) propanol 218.22
    mesitylene 53.78
    ε-caprolactone 614.79
    p-cymene 45.31
    epichlorohydrin 710.09
    1,1,1-trichloroethane 275.01
    2-aminoethanol 155.03
    morpholine-4-carbaldehyde 573.79
    sulfolane 1142.37
    2,2,4-trimethylpentane 12.04
    2-methyltetrahydrofuran 508.09
    n-hexyl acetate 272.76
    isooctane 8.4
    2-(2-butoxyethoxy)ethanol 363.01
    sec-butyl acetate 250.96
    tert-butyl acetate 406.38
    decalin 20.5
    glycerin 183.41
    diglyme 813.34
    acrylic acid 167.09
    isopropyl myristate 78.31
    n-butyric acid 522.52
    acetyl acetate 253.33
    di(2-ethylhexyl) phthalate 81.48
    ethyl propionate 276.83
    nitromethane 785.98
    1,2-diethoxyethane 335.94
    benzonitrile 167.91
    trioctyl phosphate 65.0
    1-bromopropane 157.72
    gamma-valerolactone 1013.43
    n-decanol 52.06
    triethyl phosphate 112.31
    4-methyl-2-pentanol 130.25
    propionitrile 144.43
    vinylene carbonate 292.23
    1,1,2-trichlorotrifluoroethane 591.19
    DMS 173.04
    cumene 45.56
    2-octanol 74.25
    2-hexanone 306.38
    octyl acetate 101.31
    limonene 83.51
    1,2-dimethoxyethane 735.54
    ethyl orthosilicate 112.27
    tributyl phosphate 91.04
    diacetone alcohol 485.08
    N,N-dimethylaniline 110.74
    acrylonitrile 174.75
    aniline 108.73
    1,3-propanediol 315.3
    bromobenzene 114.75
    dibromomethane 251.45
    1,1,2,2-tetrachloroethane 588.88
    2-methyl-cyclohexyl acetate 187.36
    tetrabutyl urea 120.25
    diisobutyl methanol 74.32
    2-phenylethanol 126.57
    styrene 63.12
    dioctyl adipate 152.27
    dimethyl sulfate 230.55
    ethyl butyrate 237.64
    methyl lactate 174.16
    butyl lactate 241.41
    diethyl carbonate 138.34
    propanediol butyl ether 278.07
    triethyl orthoformate 165.84
    p-tert-butyltoluene 45.06
    methyl 4-tert-butylbenzoate 208.2
    morpholine 645.98
    tert-butylamine 219.22
    n-dodecanol 36.74
    dimethoxymethane 391.0
    ethylene carbonate 284.67
    cyrene 233.44
    2-ethoxyethyl acetate 351.29
    2-ethylhexyl acetate 204.78
    1,2,4-trichlorobenzene 171.05
    4-methylpyridine 244.57
    dibutyl ether 140.97
    2,6-dimethyl-4-heptanol 74.32
    DEF 473.74
    dimethyl isosorbide 394.25
    tetrachloroethylene 378.89
    eugenol 188.25
    triacetin 319.52
    span 80 203.87
    1,4-butanediol 117.68
    1,1-dichloroethane 259.7
    2-methyl-1-pentanol 200.01
    methyl formate 182.88
    2-methyl-1-butanol 228.6
    n-decane 9.2
    butyronitrile 196.63
    3,7-dimethyl-1-octanol 99.06
    1-chlorooctane 58.29
    1-chlorotetradecane 17.66
    n-nonane 8.81
    undecane 6.0
    tert-butylcyclohexane 16.35
    cyclooctane 10.72
    cyclopentanol 327.59
    tetrahydropyran 503.78
    tert-amyl methyl ether 214.91
    2,5,8-trioxanonane 455.84
    1-hexene 54.84
    2-isopropoxyethanol 344.72
    2,2,2-trifluoroethanol 140.86
    methyl butyrate 472.79

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction