Monoethyl phthalate

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  • Identifiers

    CAS number
    2306-33-4

    Molecular formula
    C10H10O4

    SMILES
    CCOC(=O)C1=CC=CC=C1C(=O)O

    Safety labels

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 54.95%
    Phenolic 41.63%
    Balsamic 34.84%
    Floral 34.13%
    Animal 29.6%
    Grape 29.4%
    Burnt 28.99%
    Sour 28.3%
    Aromatic 28.2%
    Winey 27.17%

     

    Flavor
    Sweet 38.21%
    Balsam 37.81%
    Odorless 37.55%
    Faint 34.49%
    Wintergreen 32.23%
    Powdery 31.08%
    Grape 29.9%
    Mild 29.41%
    Fruity 28.13%
    Strawberry 27.99%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    5.65 (weak acid)

    Molecular weight
    194.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    314°C

    Flash point

    • 161.35 ˚C est.

  • Synonyms

    • Monoethyl phthalate
    • 2306-33-4
    • 2-(Ethoxycarbonyl)benzoic acid
    • Phthalic acid, monoethyl ester
    • 2-ethoxycarbonylbenzoic acid
    • Ethyl 2-Carboxybenzoate
    • phthalic acid monoethyl ester
    • 1,2-Benzenecarboxylic acid, monoethyl ester
    • 1,2-Benzenedicarboxylic acid, monoethyl ester
    • BRN 1956404
    • AI3-02249
    • 2-(Ethoxycarbonyl)benzoate
    • ETHYL PHTHALATE MONO
    • DTXSID3052696
    • CHEBI:70973
    • 4-09-00-03171 (Beilstein Handbook Reference)
    • monoethylphthalate
    • mono-ethyl phthalate
    • 14C-monoethyl phthalate
    • mEtP
    • 1,2-Benzenedicarboxylic acid, 1-ethyl ester; 1,2-Benzenedicarboxylic acid, monoethyl ester (9CI); Phthalic acid, ethyl ester (6CI,7CI); Phthalic acid, monoethyl ester (8CI); Ethyl 2-carboxybenzoate; Monoethyl phthalate
    • starbld0016608
    • NKH4WF48DS
    • A1D6Y
    • SCHEMBL50234
    • 1,2-BENZENEDICARBOXYLIC ACDI,1-ETHYL ESTER
    • DTXCID7031294
    • 2-(Ethoxycarbonyl)benzoic acid #
    • AKOS006240211
    • FM26060
    • AS-86381
    • DA-65596
    • HY-133668
    • 1,2-Benzenedicarboxylic acid, 1-ethyl ester
    • CS-0128494
    • NS00010914
    • F70724
    • Q26840768
    • Ethyl 2-carboxybenzoate;Phthalic acid monoethyl ester;1,2-Benzenedicarboxylic acid monoethyl ester

  • Applications

    Monoethyl phthalate (CAS 2306-33-4) is the monoester of phthalic acid and ethanol, commonly regarded as an intermediate in the synthesis of phthalate plasticizers and specialty polymers; it is used as an intermediate in esterification to produce phthalate derivatives employed in plastics, coatings, and adhesives; in addition, MEP is used in analytical applications as a reference standard for assessing phthalate exposure in humans and the environment; it is also studied as a degradation product or impurity that can appear in phthalate-containing formulations and during polymer processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 138.9
    methanol 206.72
    isopropanol 91.44
    water 0.29
    ethyl acetate 66.66
    n-propanol 103.45
    acetone 164.68
    n-butanol 85.73
    acetonitrile 96.56
    DMF 1368.92
    toluene 90.21
    isobutanol 62.04
    1,4-dioxane 182.6
    methyl acetate 136.0
    THF 218.2
    2-butanone 179.41
    n-pentanol 63.92
    sec-butanol 111.09
    n-hexane 2.34
    ethylene glycol 42.75
    NMP 614.63
    cyclohexane 3.46
    DMSO 826.82
    n-butyl acetate 68.33
    n-octanol 29.83
    chloroform 124.66
    n-propyl acetate 51.32
    acetic acid 68.95
    dichloromethane 196.92
    cyclohexanone 179.06
    propylene glycol 29.13
    isopropyl acetate 36.62
    DMAc 824.7
    2-ethoxyethanol 124.32
    isopentanol 70.97
    n-heptane 1.54
    ethyl formate 52.7
    1,2-dichloroethane 218.74
    n-hexanol 56.66
    2-methoxyethanol 241.52
    isobutyl acetate 20.96
    tetrachloromethane 12.88
    n-pentyl acetate 41.99
    transcutol 170.86
    n-heptanol 30.46
    ethylbenzene 48.34
    MIBK 50.81
    2-propoxyethanol 109.78
    tert-butanol 137.79
    MTBE 91.15
    2-butoxyethanol 63.17
    propionic acid 62.13
    o-xylene 65.26
    formic acid 57.48
    diethyl ether 84.89
    m-xylene 48.59
    p-xylene 48.72
    chlorobenzene 73.0
    dimethyl carbonate 66.09
    n-octane 1.32
    formamide 189.72
    cyclopentanone 232.47
    2-pentanone 105.47
    anisole 97.46
    cyclopentyl methyl ether 95.28
    gamma-butyrolactone 246.91
    1-methoxy-2-propanol 141.92
    pyridine 206.78
    3-pentanone 96.73
    furfural 209.18
    n-dodecane 1.88
    diethylene glycol 98.1
    diisopropyl ether 15.06
    tert-amyl alcohol 147.87
    acetylacetone 90.16
    n-hexadecane 2.2
    acetophenone 93.59
    methyl propionate 114.46
    isopentyl acetate 53.59
    trichloroethylene 306.78
    n-nonanol 28.13
    cyclohexanol 76.1
    benzyl alcohol 90.42
    2-ethylhexanol 31.25
    isooctanol 23.78
    dipropyl ether 24.74
    1,2-dichlorobenzene 72.79
    ethyl lactate 33.62
    propylene carbonate 83.14
    n-methylformamide 312.93
    2-pentanol 56.98
    n-pentane 2.27
    1-propoxy-2-propanol 65.24
    1-methoxy-2-propyl acetate 61.32
    2-(2-methoxypropoxy) propanol 64.8
    mesitylene 23.56
    ε-caprolactone 134.71
    p-cymene 20.51
    epichlorohydrin 303.98
    1,1,1-trichloroethane 75.55
    2-aminoethanol 79.27
    morpholine-4-carbaldehyde 311.84
    sulfolane 380.02
    2,2,4-trimethylpentane 2.95
    2-methyltetrahydrofuran 155.82
    n-hexyl acetate 58.49
    isooctane 1.56
    2-(2-butoxyethoxy)ethanol 78.93
    sec-butyl acetate 30.88
    tert-butyl acetate 51.76
    decalin 5.32
    glycerin 53.68
    diglyme 156.38
    acrylic acid 70.95
    isopropyl myristate 21.29
    n-butyric acid 55.82
    acetyl acetate 33.13
    di(2-ethylhexyl) phthalate 26.55
    ethyl propionate 48.53
    nitromethane 207.91
    1,2-diethoxyethane 63.04
    benzonitrile 80.63
    trioctyl phosphate 20.6
    1-bromopropane 87.47
    gamma-valerolactone 249.38
    n-decanol 22.07
    triethyl phosphate 31.0
    4-methyl-2-pentanol 28.36
    propionitrile 88.9
    vinylene carbonate 81.52
    1,1,2-trichlorotrifluoroethane 152.05
    DMS 61.61
    cumene 25.91
    2-octanol 23.2
    2-hexanone 64.13
    octyl acetate 30.97
    limonene 28.48
    1,2-dimethoxyethane 213.98
    ethyl orthosilicate 27.88
    tributyl phosphate 22.09
    diacetone alcohol 89.93
    N,N-dimethylaniline 74.83
    acrylonitrile 141.62
    aniline 118.27
    1,3-propanediol 96.3
    bromobenzene 72.01
    dibromomethane 125.84
    1,1,2,2-tetrachloroethane 223.67
    2-methyl-cyclohexyl acetate 38.36
    tetrabutyl urea 36.59
    diisobutyl methanol 18.96
    2-phenylethanol 66.89
    styrene 59.4
    dioctyl adipate 33.17
    dimethyl sulfate 151.2
    ethyl butyrate 38.88
    methyl lactate 61.03
    butyl lactate 36.28
    diethyl carbonate 32.22
    propanediol butyl ether 49.49
    triethyl orthoformate 30.39
    p-tert-butyltoluene 19.55
    methyl 4-tert-butylbenzoate 64.48
    morpholine 241.44
    tert-butylamine 62.19
    n-dodecanol 16.74
    dimethoxymethane 250.75
    ethylene carbonate 60.44
    cyrene 78.43
    2-ethoxyethyl acetate 60.31
    2-ethylhexyl acetate 43.38
    1,2,4-trichlorobenzene 95.72
    4-methylpyridine 231.26
    dibutyl ether 28.29
    2,6-dimethyl-4-heptanol 18.96
    DEF 222.37
    dimethyl isosorbide 104.9
    tetrachloroethylene 133.25
    eugenol 68.47
    triacetin 51.71
    span 80 44.0
    1,4-butanediol 37.44
    1,1-dichloroethane 113.38
    2-methyl-1-pentanol 62.58
    methyl formate 157.27
    2-methyl-1-butanol 83.5
    n-decane 2.79
    butyronitrile 68.48
    3,7-dimethyl-1-octanol 27.93
    1-chlorooctane 18.77
    1-chlorotetradecane 8.24
    n-nonane 2.26
    undecane 2.25
    tert-butylcyclohexane 4.19
    cyclooctane 1.36
    cyclopentanol 73.41
    tetrahydropyran 121.11
    tert-amyl methyl ether 95.87
    2,5,8-trioxanonane 110.52
    1-hexene 20.35
    2-isopropoxyethanol 73.16
    2,2,2-trifluoroethanol 35.2
    methyl butyrate 68.95

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction