Monensin Sodium

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  • Identifiers

    CAS number
    22373-78-0

    Molecular formula
    C36H61NaO11

    SMILES
    CC[C@]1(CC[C@@H](O1)[C@@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@@H](C)[C@H]([C@H](C)C(=O)[O-])OC)C)O)C)[C@H]4[C@H](C[C@@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C.[Na+]

    Safety labels

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 50.96%
    Cooling 30.62%
    Mint 28.82%
    Milky 22.23%
    Woody 22.19%
    Sweet 20.84%
    Creamy 18.69%
    Lactonic 18.06%
    Savory 17.56%
    Fresh 15.94%

     

    Flavor
    Bitter 42.61%
    Fatty 28.19%
    Sweet-like 23.65%
    Odorless 22.87%
    Metallic 22.49%
    Cedarleaf 21.88%
    Minty 21.12%
    Bouillon 21.0%
    Cauliflower 20.7%
    Mentholic 20.65%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    4.56 (weak acid)

    Molecular weight
    692.9 g/mol

    Flash point

    • 182.83 ˚C est.

  • Synonyms

    • Monensin sodium
    • 22373-78-0
    • Sodium monensin
    • Rumensin
    • Coban
    • DTXSID2045573
    • DTXCID0025573
    • NSC343257
    • Cattle Block M
    • NSC-343257
    • RefChem:57077
    • Monensin Monosodium Salt
    • Coban 60, Coban 90
    • Sweetlix Rumensin Pressed Block
    • 1,6-Dioxaspiro(4.5)decane-7-butyric acid, 2-(5-ethyltetrahydro-5-(tetrahydro-3-methyl-5-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl)-2-furyl)-2-furyl)-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, monosodium salt
    • 4-(2-(5-ethyl-5-(5-(6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl)-3-methyloxolan-2-yl)oxolan-2-yl)-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro(4.5)decan-9-yl)-3-methoxy-2-methylpentanoic acid
    • 1GS872GAFV
    • Monensin sodium salt
    • Monensin A sodium salt
    • C36H61NaO11
    • sodium (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3'-methyl-[2,2'-bioxolan]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoate
    • sodium;(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate
    • NCGC00017089-01
    • CAS-22373-78-0
    • MLS002153986
    • Monensin (sodium) (Standard)
    • orb1309997
    • orb3025311
    • SCHEMBL4057708
    • HY-N0150R
    • MSK7602
    • HMS2097E18
    • HMS3714E18
    • HY-N0150
    • Tox21_110771
    • Tox21_113191
    • HB4882
    • MSK7602-100M
    • s2324
    • AKOS025147337
    • MSK7602-1000M
    • AM26044
    • AS-0826
    • CCG-220748
    • EBC-615942
    • SMR001233320
    • CS-0007881
    • M2573
    • E78700
    • Monensin sodium 100 microg/mL in Acetonitrile
    • Monensin sodium salt Solution in Methanol, 1000ug/mL
    • Monensin sodium salt Solution in Methanol, 100ug/mL
    • Sodium (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3'-methyl[2,2'-bioxolan]-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoate
    • sodium;(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methyl-pentanoate
    • 22373-78-0

  • Applications

    Monensin sodium is mainly used in animal agriculture as a veterinary feed additive to prevent and control coccidiosis in poultry, and as a feed additive for ruminants to modulate rumen fermentation and improve feed efficiency. In scientific settings it is regarded as an ionophore antibiotic used in laboratory studies to evaluate cation transport mechanisms and effects on gut microbiota. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 184.56
    methanol 348.15
    isopropanol 68.91
    water 1.33
    ethyl acetate 97.25
    n-propanol 158.0
    acetone 165.35
    n-butanol 75.06
    acetonitrile 52.62
    DMF 570.82
    toluene 22.72
    isobutanol 60.72
    1,4-dioxane 179.94
    methyl acetate 102.39
    THF 463.23
    2-butanone 137.07
    n-pentanol 48.66
    sec-butanol 51.95
    n-hexane 0.57
    ethylene glycol 76.87
    NMP 782.56
    cyclohexane 0.81
    DMSO 581.98
    n-butyl acetate 33.82
    n-octanol 16.59
    chloroform 197.03
    n-propyl acetate 44.51
    acetic acid 686.69
    dichloromethane 185.65
    cyclohexanone 185.77
    propylene glycol 118.71
    isopropyl acetate 52.27
    DMAc 560.36
    2-ethoxyethanol 240.63
    isopentanol 31.2
    n-heptane 0.47
    ethyl formate 97.22
    1,2-dichloroethane 87.41
    n-hexanol 24.36
    2-methoxyethanol 456.26
    isobutyl acetate 24.04
    tetrachloromethane 19.93
    n-pentyl acetate 45.41
    transcutol 215.68
    n-heptanol 21.69
    ethylbenzene 7.85
    MIBK 39.13
    2-propoxyethanol 197.73
    tert-butanol 32.17
    MTBE 22.05
    2-butoxyethanol 123.02
    propionic acid 181.98
    o-xylene 11.14
    formic acid 418.4
    diethyl ether 38.92
    m-xylene 11.66
    p-xylene 7.92
    chlorobenzene 40.7
    dimethyl carbonate 119.72
    n-octane 0.25
    formamide 354.33
    cyclopentanone 365.27
    2-pentanone 94.42
    anisole 35.49
    cyclopentyl methyl ether 88.43
    gamma-butyrolactone 520.23
    1-methoxy-2-propanol 281.33
    pyridine 177.82
    3-pentanone 68.91
    furfural 347.74
    n-dodecane 0.22
    diethylene glycol 166.08
    diisopropyl ether 5.37
    tert-amyl alcohol 30.57
    acetylacetone 146.07
    n-hexadecane 0.25
    acetophenone 59.38
    methyl propionate 130.87
    isopentyl acetate 28.46
    trichloroethylene 262.55
    n-nonanol 16.64
    cyclohexanol 37.85
    benzyl alcohol 65.69
    2-ethylhexanol 9.47
    isooctanol 13.61
    dipropyl ether 13.75
    1,2-dichlorobenzene 36.4
    ethyl lactate 51.27
    propylene carbonate 191.67
    n-methylformamide 399.52
    2-pentanol 24.97
    n-pentane 0.75
    1-propoxy-2-propanol 86.5
    1-methoxy-2-propyl acetate 84.09
    2-(2-methoxypropoxy) propanol 68.53
    mesitylene 4.51
    ε-caprolactone 234.84
    p-cymene 4.36
    epichlorohydrin 434.19
    1,1,1-trichloroethane 54.83
    2-aminoethanol 187.99
    morpholine-4-carbaldehyde 575.14
    sulfolane 592.35
    2,2,4-trimethylpentane 0.49
    2-methyltetrahydrofuran 142.49
    n-hexyl acetate 47.99
    isooctane 0.27
    2-(2-butoxyethoxy)ethanol 100.21
    sec-butyl acetate 25.7
    tert-butyl acetate 41.18
    decalin 0.64
    glycerin 205.15
    diglyme 191.97
    acrylic acid 239.32
    isopropyl myristate 9.8
    n-butyric acid 202.84
    acetyl acetate 86.72
    di(2-ethylhexyl) phthalate 23.92
    ethyl propionate 42.21
    nitromethane 660.33
    1,2-diethoxyethane 37.75
    benzonitrile 39.28
    trioctyl phosphate 15.84
    1-bromopropane 29.66
    gamma-valerolactone 793.68
    n-decanol 8.9
    triethyl phosphate 19.06
    4-methyl-2-pentanol 10.53
    propionitrile 40.8
    vinylene carbonate 210.52
    1,1,2-trichlorotrifluoroethane 411.69
    DMS 49.7
    cumene 4.36
    2-octanol 9.52
    2-hexanone 42.09
    octyl acetate 20.77
    limonene 6.35
    1,2-dimethoxyethane 161.04
    ethyl orthosilicate 15.55
    tributyl phosphate 14.58
    diacetone alcohol 83.11
    N,N-dimethylaniline 22.14
    acrylonitrile 79.66
    aniline 56.63
    1,3-propanediol 207.19
    bromobenzene 34.79
    dibromomethane 89.37
    1,1,2,2-tetrachloroethane 159.75
    2-methyl-cyclohexyl acetate 25.89
    tetrabutyl urea 22.31
    diisobutyl methanol 3.92
    2-phenylethanol 43.18
    styrene 9.82
    dioctyl adipate 26.06
    dimethyl sulfate 230.66
    ethyl butyrate 27.47
    methyl lactate 154.71
    butyl lactate 52.32
    diethyl carbonate 18.76
    propanediol butyl ether 103.81
    triethyl orthoformate 22.79
    p-tert-butyltoluene 4.13
    methyl 4-tert-butylbenzoate 64.77
    morpholine 294.41
    tert-butylamine 8.12
    n-dodecanol 4.73
    dimethoxymethane 324.43
    ethylene carbonate 152.35
    cyrene 134.83
    2-ethoxyethyl acetate 93.9
    2-ethylhexyl acetate 20.54
    1,2,4-trichlorobenzene 56.25
    4-methylpyridine 124.68
    dibutyl ether 8.34
    2,6-dimethyl-4-heptanol 3.92
    DEF 150.2
    dimethyl isosorbide 114.09
    tetrachloroethylene 107.97
    eugenol 64.46
    triacetin 87.54
    span 80 67.71
    1,4-butanediol 78.35
    1,1-dichloroethane 65.07
    2-methyl-1-pentanol 25.71
    methyl formate 251.77
    2-methyl-1-butanol 41.52
    n-decane 0.51
    butyronitrile 33.09
    3,7-dimethyl-1-octanol 10.75
    1-chlorooctane 4.61
    1-chlorotetradecane 1.17
    n-nonane 0.4
    undecane 0.31
    tert-butylcyclohexane 0.47
    cyclooctane 0.33
    cyclopentanol 89.0
    tetrahydropyran 95.75
    tert-amyl methyl ether 21.36
    2,5,8-trioxanonane 105.08
    1-hexene 3.53
    2-isopropoxyethanol 104.77
    2,2,2-trifluoroethanol 256.84
    methyl butyrate 57.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction