Mogroside IV

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  • Identifiers

    CAS number
    89590-95-4

    Molecular formula
    C54H92O24

    SMILES
    CC(CCC(C(C)(C)O)OC1C(C(C(C(O1)CO)O)O)OC2C(C(C(C(O2)CO)O)O)O)C3CCC4(C3(CC(C5(C4CC=C6C5CCC(C6(C)C)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Odorless 58.72%
    Woody 36.55%
    Sweet 33.49%
    Cooling 27.27%
    Mint 24.27%
    Spicy 23.23%
    Amber 22.12%
    Balsamic 21.58%
    Dry 20.86%
    Sandalwood 20.17%

     

    Flavor
    Bitter 46.91%
    Sweet 40.84%
    Odorless 37.08%
    Fatty 30.85%
    Sweet-like 28.42%
    Bland 23.09%
    Cedarleaf 21.12%
    Mentholic 21.11%
    Cauliflower 20.56%
    Patchouli 20.42%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.5

    pKa est.
    4.97 (weak acid)

    Molecular weight
    1125.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    3646°C

    Flash point

    • 235.66 ˚C est.

  • Synonyms

    • Mogroside IV
    • 89590-95-4
    • 2-[[6-[[17-[5-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-hydroxy-6-methylheptan-2-yl]-11-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • 2-((6-((17-(5-(4,5-dihydroxy-6-(hydroxymethyl)-3-(3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxan-2-yl)oxy-6-hydroxy-6-methylheptan-2-yl)-11-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta(a)phenanthren-3-yl)oxy)-3,4,5-trihydroxyoxan-2-yl)methoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
    • RefChem:159317
    • Mogroside IVe
    • 88915-64-4
    • SCHEMBL21980494
    • MSK40192
    • MFCD21363976
    • MM45011
    • 89590-95-4

  • Applications

    Mogroside IV is used as a natural, high-intensity sweetener in food and beverage formulations to replace sugar; it is commonly evaluated for confectionery, dairy, and bakery applications where low-calorie sweetness is desired; it may also function as a taste-modifying ingredient in flavor systems and is often considered for pharmaceutical taste masking in syrups and chewable dosage forms.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.17
    methanol 24.55
    isopropanol 0.63
    water 0.27
    ethyl acetate 1.73
    n-propanol 0.98
    acetone 4.11
    n-butanol 0.4
    acetonitrile 1.67
    DMF 47.35
    toluene 0.4
    isobutanol 0.4
    1,4-dioxane 7.76
    methyl acetate 2.37
    THF 10.85
    2-butanone 1.97
    n-pentanol 0.39
    sec-butanol 0.37
    n-hexane 0.02
    ethylene glycol 6.09
    NMP 35.88
    cyclohexane 0.04
    DMSO 53.85
    n-butyl acetate 0.8
    n-octanol 0.81
    chloroform 2.86
    n-propyl acetate 0.88
    acetic acid 22.64
    dichloromethane 2.99
    cyclohexanone 2.44
    propylene glycol 3.29
    isopropyl acetate 1.04
    DMAc 34.26
    2-ethoxyethanol 7.25
    isopentanol 0.25
    n-heptane 0.05
    ethyl formate 2.2
    1,2-dichloroethane 1.36
    n-hexanol 0.38
    2-methoxyethanol 16.23
    isobutyl acetate 0.49
    tetrachloromethane 0.38
    n-pentyl acetate 1.79
    transcutol 16.12
    n-heptanol 0.89
    ethylbenzene 0.2
    MIBK 0.76
    2-propoxyethanol 7.35
    tert-butanol 0.49
    MTBE 0.44
    2-butoxyethanol 6.38
    propionic acid 2.79
    o-xylene 0.34
    formic acid 45.1
    diethyl ether 0.79
    m-xylene 0.33
    p-xylene 0.25
    chlorobenzene 0.51
    dimethyl carbonate 6.72
    n-octane 0.04
    formamide 30.54
    cyclopentanone 6.31
    2-pentanone 1.3
    anisole 1.13
    cyclopentyl methyl ether 1.82
    gamma-butyrolactone 11.39
    1-methoxy-2-propanol 7.88
    pyridine 4.0
    3-pentanone 1.28
    furfural 15.71
    n-dodecane 0.02
    diethylene glycol 11.85
    diisopropyl ether 0.17
    tert-amyl alcohol 0.37
    acetylacetone 5.45
    n-hexadecane 0.03
    acetophenone 1.84
    methyl propionate 2.99
    isopentyl acetate 0.67
    trichloroethylene 4.54
    n-nonanol 0.84
    cyclohexanol 0.34
    benzyl alcohol 1.31
    2-ethylhexanol 0.24
    isooctanol 0.56
    dipropyl ether 0.73
    1,2-dichlorobenzene 0.65
    ethyl lactate 2.13
    propylene carbonate 3.98
    n-methylformamide 18.93
    2-pentanol 0.21
    n-pentane 0.03
    1-propoxy-2-propanol 3.78
    1-methoxy-2-propyl acetate 3.79
    2-(2-methoxypropoxy) propanol 4.81
    mesitylene 0.19
    ε-caprolactone 2.99
    p-cymene 0.21
    epichlorohydrin 8.96
    1,1,1-trichloroethane 0.68
    2-aminoethanol 5.36
    morpholine-4-carbaldehyde 39.39
    sulfolane 28.5
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 1.64
    n-hexyl acetate 1.77
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 7.31
    sec-butyl acetate 0.47
    tert-butyl acetate 1.11
    decalin 0.03
    glycerin 12.89
    diglyme 15.99
    acrylic acid 6.82
    isopropyl myristate 0.44
    n-butyric acid 1.8
    acetyl acetate 2.57
    di(2-ethylhexyl) phthalate 1.04
    ethyl propionate 0.94
    nitromethane 36.73
    1,2-diethoxyethane 2.39
    benzonitrile 1.03
    trioctyl phosphate 0.7
    1-bromopropane 0.29
    gamma-valerolactone 24.12
    n-decanol 0.48
    triethyl phosphate 0.8
    4-methyl-2-pentanol 0.16
    propionitrile 0.83
    vinylene carbonate 5.62
    1,1,2-trichlorotrifluoroethane 22.66
    DMS 2.85
    cumene 0.14
    2-octanol 0.46
    2-hexanone 0.79
    octyl acetate 0.89
    limonene 0.24
    1,2-dimethoxyethane 8.79
    ethyl orthosilicate 0.7
    tributyl phosphate 0.56
    diacetone alcohol 2.72
    N,N-dimethylaniline 1.09
    acrylonitrile 2.47
    aniline 0.81
    1,3-propanediol 3.24
    bromobenzene 0.44
    dibromomethane 1.09
    1,1,2,2-tetrachloroethane 2.95
    2-methyl-cyclohexyl acetate 0.8
    tetrabutyl urea 1.13
    diisobutyl methanol 0.17
    2-phenylethanol 1.26
    styrene 0.23
    dioctyl adipate 1.14
    dimethyl sulfate 16.57
    ethyl butyrate 0.81
    methyl lactate 7.25
    butyl lactate 2.66
    diethyl carbonate 0.63
    propanediol butyl ether 7.13
    triethyl orthoformate 1.11
    p-tert-butyltoluene 0.22
    methyl 4-tert-butylbenzoate 4.0
    morpholine 7.18
    tert-butylamine 0.15
    n-dodecanol 0.28
    dimethoxymethane 20.22
    ethylene carbonate 3.06
    cyrene 9.6
    2-ethoxyethyl acetate 5.42
    2-ethylhexyl acetate 0.53
    1,2,4-trichlorobenzene 1.04
    4-methylpyridine 1.88
    dibutyl ether 0.43
    2,6-dimethyl-4-heptanol 0.17
    DEF 3.72
    dimethyl isosorbide 9.48
    tetrachloroethylene 2.55
    eugenol 4.24
    triacetin 5.54
    span 80 4.46
    1,4-butanediol 1.58
    1,1-dichloroethane 0.66
    2-methyl-1-pentanol 0.24
    methyl formate 17.6
    2-methyl-1-butanol 0.26
    n-decane 0.06
    butyronitrile 0.46
    3,7-dimethyl-1-octanol 0.38
    1-chlorooctane 0.24
    1-chlorotetradecane 0.07
    n-nonane 0.05
    undecane 0.04
    tert-butylcyclohexane 0.02
    cyclooctane 0.03
    cyclopentanol 0.74
    tetrahydropyran 1.36
    tert-amyl methyl ether 0.44
    2,5,8-trioxanonane 10.02
    1-hexene 0.08
    2-isopropoxyethanol 3.1
    2,2,2-trifluoroethanol 10.85
    methyl butyrate 1.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction