Methyltrimethoxysilane

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  • Identifiers

    CAS number
    1185-55-3

    Molecular formula
    C4H12O3Si

    SMILES
    CO[Si](C)(OC)OC

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Ethereal 60.47%
    Fresh 39.16%
    Alcoholic 36.32%
    Fruity 35.69%
    Odorless 30.81%
    Sweet 28.66%
    Green 25.67%
    Sharp 25.05%
    Fermented 23.24%
    Earthy 22.44%

     

    Flavor
    Green 71.65%
    Sweet 65.74%
    Ether 42.5%
    Fruity 40.78%
    Earthy 40.66%
    Vegetable 35.06%
    Sharp 34.87%
    Bitter 34.08%
    Fruit 32.08%
    Alcohol 30.73%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    11.93 (strong base)

    Molecular weight
    136.22 g/mol

    Flash point

    • 11.49 ˚C est.

  • Synonyms

    • Methyltrimethoxysilane
    • Trimethoxy(methyl)silane
    • 1185-55-3
    • Trimethoxymethylsilane
    • Silane, trimethoxymethyl-
    • Z 6070
    • 0HI0D71MCI
    • DTXSID3027370
    • GLASCA B
    • NSC-93883
    • SILQUEST A 1630
    • DTXCID407370
    • DOW CORNING 7-5300 FILM-IN-PLACE COATING
    • DOW CORNING (R) 7-5310 FILM-IN-PLACE BASE
    • RefChem:818737
    • 214-685-0
    • Union carbide A-163
    • SILANE, METHYLTRIMETHOXY-
    • MFCD00008342
    • methyl-trimethoxysilane
    • S11825
    • Silane A-163
    • Dynasylan MTMS
    • C4H12O3Si
    • 25498-03-7
    • methyl trimethoxysilane
    • EINECS 214-685-0
    • CM9100
    • NSC 93883
    • 25498-02-6
    • UNII-0HI0D71MCI
    • methyltrimetoxysilane
    • methyltrimethoxy silane
    • trimethoxy-methyl-silane
    • EC 214-685-0
    • CH3Si(OCH3)3
    • Trimethoxymethylsilane, 95%
    • Trimethoxymethylsilane, 98%
    • Methyltrimethoxysilane (MTM)
    • SCHEMBL35033
    • SCHEMBL768328
    • (TRIMETHOXYSILYL)METHANE
    • CHEMBL3182654
    • SCHEMBL15194700
    • 1,1,1-trimethoxy-1-silaethane
    • BFXIKLCIZHOAAZ-UHFFFAOYSA-
    • NSC93883
    • WLN: 1O-SI-1&O1&O1
    • Tox21_200453
    • MFCD00081866
    • AKOS008901240
    • NCGC00248627-01
    • NCGC00258007-01
    • LS-13028
    • CAS-1185-55-3
    • DB-030050
    • M0660
    • NS00044808
    • ST51037340
    • E75871
    • EN300-218612
    • METHYLSILICON TRIMETHOXIDE (MESI(OME)3)
    • Trimethoxymethylsilane, purum, >=98.0% (GC)
    • Trimethoxymethylsilane, deposition grade, >=98%
    • A804054
    • Q21099559
    • InChI=1/C4H12O3Si/c1-5-8(4,6-2)7-3/h1-4H3
    • 1185-55-3

  • Applications

    Methyltrimethoxysilane (CAS 1185-55-3) is widely used as a silane coupling agent and crosslinking precursor in coatings, adhesives, sealants, and silicone resins. Through hydrolysis and condensation, it forms Si–O–Si networks while introducing a methyl group that promotes adhesion to inorganic substrates such as glass, metal, and concrete and improves moisture resistance and durability. It serves as a reactive intermediate in sol–gel processes to produce organically modified silica (ORMOSIL) and hybrid coatings with hydrophobic or weather-resistant surfaces. It can also be employed as a building block for silicone-based polymers used in electronics encapsulation and protective coatings, and as a surface modifier to tailor interfacial properties in composites and adhesives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1869.72
    methanol 3080.98
    isopropanol 1331.24
    water 758.18
    ethyl acetate 424.75
    n-propanol 1441.56
    acetone 505.12
    n-butanol 1284.41
    acetonitrile 577.28
    DMF 992.33
    toluene 177.1
    isobutanol 862.94
    1,4-dioxane 885.73
    methyl acetate 443.48
    THF 1205.83
    2-butanone 482.95
    n-pentanol 678.24
    sec-butanol 1233.99
    n-hexane 137.88
    ethylene glycol 650.31
    NMP 757.32
    cyclohexane 237.45
    DMSO 830.04
    n-butyl acetate 193.23
    n-octanol 298.67
    chloroform 1841.46
    n-propyl acetate 217.21
    acetic acid 1383.97
    dichloromethane 1266.38
    cyclohexanone 542.12
    propylene glycol 744.1
    isopropyl acetate 253.76
    DMAc 791.61
    2-ethoxyethanol 1179.07
    isopentanol 675.06
    n-heptane 149.85
    ethyl formate 469.31
    1,2-dichloroethane 562.58
    n-hexanol 464.81
    2-methoxyethanol 2038.06
    isobutyl acetate 118.72
    tetrachloromethane 585.28
    n-pentyl acetate 234.49
    transcutol 753.39
    n-heptanol 390.06
    ethylbenzene 88.53
    MIBK 198.86
    2-propoxyethanol 734.09
    tert-butanol 1202.22
    MTBE 678.58
    2-butoxyethanol 594.2
    propionic acid 780.54
    o-xylene 149.52
    formic acid 1598.32
    diethyl ether 882.56
    m-xylene 118.13
    p-xylene 121.07
    chlorobenzene 217.95
    dimethyl carbonate 153.66
    n-octane 63.8
    formamide 1580.77
    cyclopentanone 602.05
    2-pentanone 393.35
    anisole 216.24
    cyclopentyl methyl ether 563.4
    gamma-butyrolactone 639.58
    1-methoxy-2-propanol 1143.3
    pyridine 522.02
    3-pentanone 303.51
    furfural 567.65
    n-dodecane 32.11
    diethylene glycol 598.64
    diisopropyl ether 211.56
    tert-amyl alcohol 1082.22
    acetylacetone 236.78
    n-hexadecane 33.3
    acetophenone 174.91
    methyl propionate 360.45
    isopentyl acetate 155.58
    trichloroethylene 836.61
    n-nonanol 258.79
    cyclohexanol 799.2
    benzyl alcohol 255.19
    2-ethylhexanol 229.57
    isooctanol 272.42
    dipropyl ether 320.25
    1,2-dichlorobenzene 208.59
    ethyl lactate 170.28
    propylene carbonate 305.32
    n-methylformamide 988.1
    2-pentanol 781.79
    n-pentane 266.12
    1-propoxy-2-propanol 454.8
    1-methoxy-2-propyl acetate 188.69
    2-(2-methoxypropoxy) propanol 223.95
    mesitylene 85.46
    ε-caprolactone 473.04
    p-cymene 95.37
    epichlorohydrin 742.48
    1,1,1-trichloroethane 606.33
    2-aminoethanol 1257.77
    morpholine-4-carbaldehyde 697.34
    sulfolane 606.03
    2,2,4-trimethylpentane 108.33
    2-methyltetrahydrofuran 876.99
    n-hexyl acetate 244.68
    isooctane 58.8
    2-(2-butoxyethoxy)ethanol 353.28
    sec-butyl acetate 154.03
    tert-butyl acetate 253.96
    decalin 63.58
    glycerin 908.47
    diglyme 711.51
    acrylic acid 627.63
    isopropyl myristate 89.07
    n-butyric acid 899.62
    acetyl acetate 203.13
    di(2-ethylhexyl) phthalate 83.4
    ethyl propionate 197.45
    nitromethane 1059.5
    1,2-diethoxyethane 300.26
    benzonitrile 211.2
    trioctyl phosphate 77.39
    1-bromopropane 504.8
    gamma-valerolactone 720.93
    n-decanol 169.28
    triethyl phosphate 114.06
    4-methyl-2-pentanol 306.33
    propionitrile 512.0
    vinylene carbonate 295.37
    1,1,2-trichlorotrifluoroethane 725.03
    DMS 103.63
    cumene 75.54
    2-octanol 262.04
    2-hexanone 227.48
    octyl acetate 126.78
    limonene 151.91
    1,2-dimethoxyethane 922.48
    ethyl orthosilicate 133.69
    tributyl phosphate 74.7
    diacetone alcohol 315.07
    N,N-dimethylaniline 191.8
    acrylonitrile 481.64
    aniline 384.39
    1,3-propanediol 1402.04
    bromobenzene 185.4
    dibromomethane 922.24
    1,1,2,2-tetrachloroethane 833.57
    2-methyl-cyclohexyl acetate 156.4
    tetrabutyl urea 95.83
    diisobutyl methanol 145.09
    2-phenylethanol 217.54
    styrene 107.75
    dioctyl adipate 105.48
    dimethyl sulfate 207.43
    ethyl butyrate 186.57
    methyl lactate 266.69
    butyl lactate 187.12
    diethyl carbonate 122.23
    propanediol butyl ether 345.38
    triethyl orthoformate 181.28
    p-tert-butyltoluene 99.53
    methyl 4-tert-butylbenzoate 218.94
    morpholine 1244.88
    tert-butylamine 915.86
    n-dodecanol 119.05
    dimethoxymethane 761.3
    ethylene carbonate 277.89
    cyrene 241.68
    2-ethoxyethyl acetate 235.28
    2-ethylhexyl acetate 135.18
    1,2,4-trichlorobenzene 237.54
    4-methylpyridine 439.91
    dibutyl ether 196.12
    2,6-dimethyl-4-heptanol 145.09
    DEF 540.51
    dimethyl isosorbide 279.92
    tetrachloroethylene 669.75
    eugenol 214.27
    triacetin 175.05
    span 80 227.56
    1,4-butanediol 543.94
    1,1-dichloroethane 673.65
    2-methyl-1-pentanol 423.87
    methyl formate 529.92
    2-methyl-1-butanol 769.64
    n-decane 64.26
    butyronitrile 575.59
    3,7-dimethyl-1-octanol 200.97
    1-chlorooctane 150.21
    1-chlorotetradecane 54.39
    n-nonane 68.6
    undecane 42.19
    tert-butylcyclohexane 64.76
    cyclooctane 101.47
    cyclopentanol 869.98
    tetrahydropyran 880.84
    tert-amyl methyl ether 552.6
    2,5,8-trioxanonane 396.45
    1-hexene 225.5
    2-isopropoxyethanol 577.92
    2,2,2-trifluoroethanol 732.75
    methyl butyrate 269.72

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction