Methylsilanol ascorbate

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  • Identifiers

    CAS number
    187991-39-5

    Molecular formula
    C7H12O8Si

    SMILES
    C[Si](O)(O)OC[C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 68.74%
    Sweet 32.87%
    Clean 21.73%
    Savory 19.02%
    Caramellic 17.7%
    Milky 17.48%
    Alcoholic 15.56%
    Bitter 15.37%
    Sharp 15.19%
    Creamy 14.8%

     

    Flavor
    Odorless 60.37%
    Very mild 33.88%
    Bitter 31.22%
    Sweet-like 27.3%
    Bland 26.1%
    Mild 25.73%
    Yeast 21.05%
    Very slight 20.62%
    Cotton candy 19.63%
    Extremely sweet 19.51%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.68 (neutral)

    Molecular weight
    252.25 g/mol

    Flash point

    • 217.62 ˚C est.

  • Synonyms

    • Methylsilanol ascorbate
    • UNII-46Z5D1I0IS
    • 46Z5D1I0IS
    • 187991-39-5
    • L-Ascorbic acid, 6-O-(dihydroxymethylsilyl)-
    • DTXSID00172130
    • RefChem:158312
    • DTXCID8094621
    • METHYLSILANOL ASCORBATE [INCI]
    • orb1739381
    • Q27258969
    • (5R)-5-[(1S)-2-{[Dihydroxy(methyl)silyl]oxy}-1-hydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
    • 187991-39-5

  • Applications

    In cosmetics and personal care, Methylsilanol ascorbate (CAS 187991-39-5) is viewed as a stabilized derivative of ascorbic acid and an antioxidant, commonly evaluated to improve the stability of vitamin C in formulations and extend product shelf life; in the chemicals and polymers sector, it can serve as an intermediate or stabilizer for silicone- and silanol-containing systems, enhancing compatibility between organic and inorganic phases; in coatings and inks, it may be used as a functional additive to improve oxidation resistance and compatibility with silica-based coatings; in adhesives, it can act as a functional additive to improve bonding between siloxane components and the resin matrix; and in industrial manufacturing, it may be used as a stabilizer or intermediate relevant to formulations requiring ascorbate stability and siloxane structures.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.65
    methanol 36.82
    isopropanol 7.52
    water 412.9
    ethyl acetate 1.94
    n-propanol 6.2
    acetone 12.61
    n-butanol 4.29
    acetonitrile 1.9
    DMF 204.79
    toluene 1.09
    isobutanol 2.64
    1,4-dioxane 8.85
    methyl acetate 1.79
    THF 24.66
    2-butanone 2.62
    n-pentanol 2.77
    sec-butanol 4.11
    n-hexane 0.47
    ethylene glycol 109.32
    NMP 99.49
    cyclohexane 1.41
    DMSO 272.82
    n-butyl acetate 1.57
    n-octanol 3.1
    chloroform 0.38
    n-propyl acetate 1.48
    acetic acid 17.52
    dichloromethane 0.62
    cyclohexanone 5.41
    propylene glycol 46.68
    isopropyl acetate 2.12
    DMAc 94.4
    2-ethoxyethanol 49.24
    isopentanol 3.27
    n-heptane 1.52
    ethyl formate 4.09
    1,2-dichloroethane 1.03
    n-hexanol 3.84
    2-methoxyethanol 122.79
    isobutyl acetate 0.5
    tetrachloromethane 0.37
    n-pentyl acetate 1.55
    transcutol 22.87
    n-heptanol 4.12
    ethylbenzene 0.62
    MIBK 3.73
    2-propoxyethanol 30.92
    tert-butanol 13.66
    MTBE 2.16
    2-butoxyethanol 16.24
    propionic acid 4.77
    o-xylene 1.56
    formic acid 200.22
    diethyl ether 3.12
    m-xylene 1.32
    p-xylene 0.65
    chlorobenzene 0.24
    dimethyl carbonate 8.44
    n-octane 0.72
    formamide 203.88
    cyclopentanone 13.57
    2-pentanone 4.68
    anisole 1.74
    cyclopentyl methyl ether 9.06
    gamma-butyrolactone 17.05
    1-methoxy-2-propanol 67.97
    pyridine 3.31
    3-pentanone 2.67
    furfural 17.84
    n-dodecane 0.37
    diethylene glycol 86.01
    diisopropyl ether 1.59
    tert-amyl alcohol 6.72
    acetylacetone 10.35
    n-hexadecane 0.4
    acetophenone 2.43
    methyl propionate 4.37
    isopentyl acetate 1.19
    trichloroethylene 0.91
    n-nonanol 3.1
    cyclohexanol 5.14
    benzyl alcohol 3.17
    2-ethylhexanol 1.99
    isooctanol 2.46
    dipropyl ether 4.04
    1,2-dichlorobenzene 0.34
    ethyl lactate 7.18
    propylene carbonate 5.42
    n-methylformamide 62.43
    2-pentanol 3.78
    n-pentane 0.74
    1-propoxy-2-propanol 16.78
    1-methoxy-2-propyl acetate 5.53
    2-(2-methoxypropoxy) propanol 13.65
    mesitylene 1.24
    ε-caprolactone 4.59
    p-cymene 1.0
    epichlorohydrin 7.44
    1,1,1-trichloroethane 0.33
    2-aminoethanol 72.34
    morpholine-4-carbaldehyde 69.22
    sulfolane 56.3
    2,2,4-trimethylpentane 0.24
    2-methyltetrahydrofuran 5.6
    n-hexyl acetate 2.01
    isooctane 0.22
    2-(2-butoxyethoxy)ethanol 18.61
    sec-butyl acetate 0.9
    tert-butyl acetate 3.87
    decalin 0.33
    glycerin 177.19
    diglyme 32.03
    acrylic acid 8.57
    isopropyl myristate 1.21
    n-butyric acid 4.47
    acetyl acetate 1.58
    di(2-ethylhexyl) phthalate 1.65
    ethyl propionate 1.87
    nitromethane 27.8
    1,2-diethoxyethane 3.4
    benzonitrile 0.98
    trioctyl phosphate 1.85
    1-bromopropane 0.48
    gamma-valerolactone 25.85
    n-decanol 2.54
    triethyl phosphate 1.91
    4-methyl-2-pentanol 2.46
    propionitrile 1.17
    vinylene carbonate 3.84
    1,1,2-trichlorotrifluoroethane 21.47
    DMS 1.66
    cumene 0.53
    2-octanol 2.29
    2-hexanone 1.56
    octyl acetate 1.81
    limonene 1.45
    1,2-dimethoxyethane 31.79
    ethyl orthosilicate 1.79
    tributyl phosphate 1.39
    diacetone alcohol 16.81
    N,N-dimethylaniline 3.43
    acrylonitrile 2.56
    aniline 2.52
    1,3-propanediol 46.25
    bromobenzene 0.19
    dibromomethane 0.43
    1,1,2,2-tetrachloroethane 1.45
    2-methyl-cyclohexyl acetate 1.73
    tetrabutyl urea 3.93
    diisobutyl methanol 2.0
    2-phenylethanol 3.34
    styrene 0.5
    dioctyl adipate 1.73
    dimethyl sulfate 25.7
    ethyl butyrate 2.05
    methyl lactate 21.25
    butyl lactate 3.97
    diethyl carbonate 1.31
    propanediol butyl ether 14.35
    triethyl orthoformate 2.5
    p-tert-butyltoluene 1.15
    methyl 4-tert-butylbenzoate 6.2
    morpholine 15.4
    tert-butylamine 5.05
    n-dodecanol 2.03
    dimethoxymethane 62.09
    ethylene carbonate 2.85
    cyrene 23.65
    2-ethoxyethyl acetate 2.58
    2-ethylhexyl acetate 0.87
    1,2,4-trichlorobenzene 0.48
    4-methylpyridine 2.42
    dibutyl ether 1.46
    2,6-dimethyl-4-heptanol 2.0
    DEF 14.48
    dimethyl isosorbide 21.82
    tetrachloroethylene 1.38
    eugenol 8.96
    triacetin 3.27
    span 80 9.64
    1,4-butanediol 20.5
    1,1-dichloroethane 0.37
    2-methyl-1-pentanol 1.66
    methyl formate 35.83
    2-methyl-1-butanol 2.57
    n-decane 0.61
    butyronitrile 1.19
    3,7-dimethyl-1-octanol 1.83
    1-chlorooctane 0.84
    1-chlorotetradecane 0.48
    n-nonane 0.66
    undecane 0.46
    tert-butylcyclohexane 0.21
    cyclooctane 1.05
    cyclopentanol 8.73
    tetrahydropyran 3.74
    tert-amyl methyl ether 2.89
    2,5,8-trioxanonane 29.63
    1-hexene 0.57
    2-isopropoxyethanol 17.19
    2,2,2-trifluoroethanol 21.44
    methyl butyrate 2.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction