Methylene Chloride

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  • Identifiers

    CAS number
    75-09-2

    Molecular formula
    CH2Cl2

    SMILES
    C(Cl)Cl

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Fishy 44.37%
    Cheesy 41.26%
    Fermented 35.7%
    Oily 35.69%
    Alcoholic 35.06%
    Ripe 35.0%
    Sweet 34.55%
    Odorless 29.92%
    Fruity 28.26%
    Solvent 28.06%

     

    Flavor
    Fishy 35.07%
    Odorless 28.36%
    Ammoniacal 28.04%
    Sulfurous 23.96%
    Sulfury 21.86%
    Meaty 21.71%
    Rotten 20.22%
    Egg 19.74%
    Ammonia 19.54%
    Onion 19.52%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 1.2 [mmHg]. Odor Threshold High: 440.0 [mmHg]. Detection odor threshold from AIHA (mean = 160 ppm)
    • 205-307 ppm
    • 2.14x10+2 ppm (odor recognition in air; chemically pure sample)
    • Odor thresholds: low= 540 mg/cu m; high= 2160 mg/cu m.
    • Reported and accepted odor threshold values of dichloromethane from various air samples and sources showed concentrations ranging from 500 to 790 ug/cu m, unreviewed sources reported concentrations of 0.2 to 1.4 ug/L.

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    7.39 (neutral)

    Molecular weight
    84.93 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -142.1 °F (NTP, 1992)
    • -95 °C
    • -96.8 °C
    • -97 °C
    • -139 °F

    Boiling point

    • 103.6 °F at 760 mmHg (NTP, 1992)
    • 39.75 °C at 760 mm Hg
    • 40 °C
    • 104 °F

    Flash point

    • 7.89 ˚C est.

    Solubility expt.

    • 10 to 50 mg/mL at 70 °F (NTP, 1992)
    • In water, 13,200 mg/L at 25 °C
    • In water, 13,000 mg/L at 25 °C
    • Miscible with alcohol, ether, dimethylformamide
    • Miscible with ethanol; soluble in carbon tetrachloride
    • 13 mg/mL at 25 °C
    • Solubility in water, g/100ml at 20 °C: 1.3 (moderate)
    • 2%

  • Synonyms

    • DICHLOROMETHANE
    • Methylene chloride
    • 75-09-2
    • Methylene dichloride
    • Methane, dichloro-
    • Methylene bichloride
    • Methane dichloride
    • Solaesthin
    • Solmethine
    • Narkotil
    • Freon 30
    • Aerothene MM
    • Metylenu chlorek
    • Chlorure de methylene
    • Dichlormethan
    • Metaclen
    • Soleana VDA
    • Khladon 30
    • CH2Cl2
    • F 30 (chlorocarbon)
    • Methylenum chloratum
    • R30 (refrigerant)
    • RCRA waste number U080
    • Caswell No. 568
    • dichloro-methane
    • NCI-C50102
    • R 30
    • HCC 30
    • Chloride, Methylene
    • Bichloride, Methylene
    • Dichloride, Methylene
    • HSDB 66
    • CCRIS 392
    • dichlormethane
    • Methoklone
    • Methylenchlorid
    • Salesthin
    • NSC 406122
    • DTXSID0020868
    • UN 1593
    • dichloro methane
    • Chlorodorm D
    • F 30
    • EINECS 200-838-9
    • UNII-588X2YUY0A
    • EPA Pesticide Chemical Code 042004
    • BRN 1730800
    • 588X2YUY0A
    • CHEBI:15767
    • AI3-01773
    • Methylene chloride [NF]
    • NSC-406122
    • Dichloromethane, HPLC Grade
    • DTXCID40868
    • EC 200-838-9
    • 4-01-00-00035 (Beilstein Handbook Reference)
    • MFCD00000881
    • NSC406122
    • Methylene chloride (NF)
    • DICHLOROMETHANE (IARC)
    • DICHLOROMETHANE [IARC]
    • DICHLOROMETHANE (MART.)
    • DICHLOROMETHANE [MART.]
    • METHYLENE CHLORIDE (II)
    • METHYLENE CHLORIDE [II]
    • Dichloromethane(Methylene Chloride)
    • Metylenu chlorek [Polish]
    • METHYLENE CHLORIDE (EP MONOGRAPH)
    • METHYLENE CHLORIDE [EP MONOGRAPH]
    • Methylene chloride; Dichloromethane; DCM
    • MFCD00000882
    • Chlorure de methylene [French]
    • Dichloromethane (Methylene Chloride)
    • UN1593
    • DICHLOROMETHANE, NF
    • RCRA waste no. U080
    • DICHLOROMETHANE, ACS
    • dichioromethane
    • dichlormetane
    • dichloromeihane
    • dichlorometan
    • dichlorometane
    • dichloromethan
    • dichoromethane
    • dicloromethane
    • methylenchoride
    • metylenchloride
    • Driverit
    • Nevolin
    • dichlor-methane
    • dichlorometliane
    • dichlorornethane
    • dicliloromethane
    • methylenchloride
    • methylenechlorid
    • methYIenechlorid
    • di-chloromethane
    • dichloromethane-
    • methlyenechloride
    • methylenechloride
    • methlene chloride
    • methyene chloride
    • methylen chloride
    • methylene chlorie
    • methylene cloride
    • metylene chloride
    • Methylene choride
    • mehtylene chloride
    • methlyene chloride
    • methylene,chloride
    • methylene-chloride
    • dichloro -methane
    • dichloro- methane
    • methylenedichloride
    • Distillex DS3
    • Dichloromethane, ACS reagent, >=99.5%, contains 40-150 ppm amylene as stabilizer
    • M-clean D
    • methyl ene chloride
    • MeCl2
    • methylene di chloride
    • N,N-methylenechloride
    • dichloromethane radical
    • Methylene chloride ACS
    • Cl2CH2
    • H2CCl2
    • Dichloromethane, anhydrous
    • Dichloromethane, for HPLC
    • NCIMech_000221

  • Applications

    Methylene chloride (CAS 75-09-2) is widely used as a solvent in industrial and cleaning applications, including paint stripping and coatings removal; degreasing and cleaning of metal parts and precision electronic components; formulation solvent for coatings, inks, and adhesives; processing solvent in polymer and plastics manufacturing; and as an extraction/purification solvent in pharmaceutical and botanical/natural-product processing, with use governed by local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 139.17
    methanol 145.35
    isopropanol 114.68
    water 9.23
    ethyl acetate 165.73
    n-propanol 113.05
    acetone 406.46
    n-butanol 123.14
    acetonitrile 273.81
    DMF 561.11
    toluene 179.96
    isobutanol 94.37
    1,4-dioxane 365.6
    methyl acetate 200.89
    THF 458.7
    2-butanone 244.02
    n-pentanol 89.91
    sec-butanol 105.91
    n-hexane 52.57
    ethylene glycol 61.57
    NMP 626.64
    cyclohexane 148.23
    DMSO 629.63
    n-butyl acetate 175.34
    n-octanol 85.41
    chloroform 570.38
    n-propyl acetate 138.87
    acetic acid 311.88
    dichloromethane 506.9
    cyclohexanone 424.44
    propylene glycol 50.72
    isopropyl acetate 113.82
    DMAc 451.79
    2-ethoxyethanol 146.02
    isopentanol 102.63
    n-heptane 92.66
    ethyl formate 137.67
    1,2-dichloroethane 328.92
    n-hexanol 103.71
    2-methoxyethanol 229.13
    isobutyl acetate 94.08
    tetrachloromethane 196.86
    n-pentyl acetate 122.38
    transcutol 395.53
    n-heptanol 74.34
    ethylbenzene 86.87
    MIBK 122.26
    2-propoxyethanol 163.3
    tert-butanol 149.84
    MTBE 151.59
    2-butoxyethanol 119.09
    propionic acid 131.24
    o-xylene 136.24
    formic acid 118.28
    diethyl ether 186.83
    m-xylene 113.43
    p-xylene 133.8
    chlorobenzene 237.75
    dimethyl carbonate 97.17
    n-octane 35.28
    formamide 179.78
    cyclopentanone 452.38
    2-pentanone 210.31
    anisole 164.77
    cyclopentyl methyl ether 257.52
    gamma-butyrolactone 384.53
    1-methoxy-2-propanol 162.84
    pyridine 425.73
    3-pentanone 190.08
    furfural 427.3
    n-dodecane 24.24
    diethylene glycol 140.79
    diisopropyl ether 75.94
    tert-amyl alcohol 122.76
    acetylacetone 251.42
    n-hexadecane 27.27
    acetophenone 188.07
    methyl propionate 151.03
    isopentyl acetate 137.38
    trichloroethylene 620.1
    n-nonanol 76.94
    cyclohexanol 196.18
    benzyl alcohol 127.79
    2-ethylhexanol 95.11
    isooctanol 65.37
    dipropyl ether 173.29
    1,2-dichlorobenzene 224.71
    ethyl lactate 67.84
    propylene carbonate 194.52
    n-methylformamide 209.08
    2-pentanol 95.95
    n-pentane 63.46
    1-propoxy-2-propanol 157.57
    1-methoxy-2-propyl acetate 145.15
    2-(2-methoxypropoxy) propanol 123.68
    mesitylene 83.85
    ε-caprolactone 274.23
    p-cymene 98.66
    epichlorohydrin 343.94
    1,1,1-trichloroethane 381.56
    2-aminoethanol 79.16
    morpholine-4-carbaldehyde 471.51
    sulfolane 504.76
    2,2,4-trimethylpentane 34.18
    2-methyltetrahydrofuran 331.65
    n-hexyl acetate 136.38
    isooctane 23.69
    2-(2-butoxyethoxy)ethanol 154.11
    sec-butyl acetate 92.39
    tert-butyl acetate 128.49
    decalin 49.18
    glycerin 85.48
    diglyme 348.36
    acrylic acid 155.46
    isopropyl myristate 73.15
    n-butyric acid 160.9
    acetyl acetate 139.01
    di(2-ethylhexyl) phthalate 65.27
    ethyl propionate 114.68
    nitromethane 448.37
    1,2-diethoxyethane 207.72
    benzonitrile 210.44
    trioctyl phosphate 52.59
    1-bromopropane 208.58
    gamma-valerolactone 429.91
    n-decanol 61.74
    triethyl phosphate 86.7
    4-methyl-2-pentanol 59.82
    propionitrile 155.91
    vinylene carbonate 197.23
    1,1,2-trichlorotrifluoroethane 318.8
    DMS 119.59
    cumene 67.13
    2-octanol 62.93
    2-hexanone 157.51
    octyl acetate 85.28
    limonene 153.15
    1,2-dimethoxyethane 299.48
    ethyl orthosilicate 87.83
    tributyl phosphate 62.92
    diacetone alcohol 142.44
    N,N-dimethylaniline 155.92
    acrylonitrile 211.45
    aniline 180.63
    1,3-propanediol 108.83
    bromobenzene 249.9
    dibromomethane 397.04
    1,1,2,2-tetrachloroethane 481.15
    2-methyl-cyclohexyl acetate 114.73
    tetrabutyl urea 108.98
    diisobutyl methanol 81.06
    2-phenylethanol 123.11
    styrene 126.24
    dioctyl adipate 100.96
    dimethyl sulfate 184.46
    ethyl butyrate 154.36
    methyl lactate 87.86
    butyl lactate 90.1
    diethyl carbonate 104.28
    propanediol butyl ether 108.01
    triethyl orthoformate 122.6
    p-tert-butyltoluene 95.42
    methyl 4-tert-butylbenzoate 150.07
    morpholine 356.26
    tert-butylamine 112.49
    n-dodecanol 54.15
    dimethoxymethane 252.61
    ethylene carbonate 162.17
    cyrene 148.83
    2-ethoxyethyl acetate 142.77
    2-ethylhexyl acetate 128.67
    1,2,4-trichlorobenzene 258.87
    4-methylpyridine 355.4
    dibutyl ether 133.93
    2,6-dimethyl-4-heptanol 81.06
    DEF 301.02
    dimethyl isosorbide 227.57
    tetrachloroethylene 407.47
    eugenol 141.57
    triacetin 146.16
    span 80 127.39
    1,4-butanediol 56.24
    1,1-dichloroethane 310.77
    2-methyl-1-pentanol 80.01
    methyl formate 172.8
    2-methyl-1-butanol 98.61
    n-decane 37.62
    butyronitrile 165.77
    3,7-dimethyl-1-octanol 81.83
    1-chlorooctane 88.99
    1-chlorotetradecane 46.22
    n-nonane 40.15
    undecane 28.72
    tert-butylcyclohexane 39.87
    cyclooctane 56.48
    cyclopentanol 201.2
    tetrahydropyran 343.08
    tert-amyl methyl ether 137.19
    2,5,8-trioxanonane 246.45
    1-hexene 99.9
    2-isopropoxyethanol 115.25
    2,2,2-trifluoroethanol 150.52
    methyl butyrate 154.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction